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Offlinebullethead454
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Registered: 07/15/07
Posts: 100
Last seen: 1 month, 23 days
Can't seem to "trip"
    #28684251 - 03/02/24 05:41 PM (3 months, 25 days ago)

So, I tried taking 3.5g (dried) p.cubensis mushrooms (in a tea), and nothing noticeable happened.

I tried taking 5g (dried) p.cubensis the next day (straight up), and nothing noticeable happened.

I waited a couple of days and did 4g (dried) of small pins (in a tea); nothing.

I tried 3.5g (dried) large caps and stems a day or so later (in a tea, but at all mushrooms too/didn't strain); nothing.

The first time I did mushrooms were out of a cow field next to my house (trip report: https://www.shroomery.org/2897/AHHHHHHHH), and it was about 40-50 large fresh p.cubensis.

Over the past few years, every time I do a grow and try my bounty, I am let down.

Should I be taking more? Most people say 3.5+ is a macro-dose/higher level trip, but not for me apparently.

Would my tolerance be so high from 20 years ago, or is it likely the spores I'm getting are bs? I'm also over 200lbs right now, and I take some medications (I don't think any are SSRIs).

I wouldn't have a problem taking more, but I feel like I'm just wasting them and my time.

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OfflineLSDreamer
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Re: Can't seem to "trip" [Re: bullethead454]
    #28684467 - 03/02/24 09:08 PM (3 months, 25 days ago)

What meds do you take?


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InvisibleItsLinkNotZelda
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Re: Can't seem to "trip" [Re: LSDreamer] * 1
    #28684523 - 03/02/24 10:12 PM (3 months, 25 days ago)

Were these all mushrooms that you grew yourself? Have you had anyone else try them? It could be the way you are drying them and losing potency. Maybe try some fresh one's next time, I don't know how much fresh ones you will have to eat, but I do know that it'll have to be much more than 3.5. Or you could try getting some mushrooms from someone else and see if they work a little better.

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OfflineBasicTek
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Re: Can't seem to "trip" [Re: ItsLinkNotZelda]
    #28684527 - 03/02/24 10:19 PM (3 months, 25 days ago)

I got back into shrooms late in 2022, between December 2022 and February 2023 I was able to trip daily or every other day with almost no tolerance build up. The cubes I was getting were grown by a friend, from my limited experience with shroom varieties (probably only cubes) very consistent and pretty strong. I was getting a trip equivalent to what I took 1g-6g every time I took em. I did as many as 8g a night later in 2023 up to 3 nights in a row and had pretty equivalent trips, so don't think most of what I read about tolerance is true especially after a long period of time.

Do you have anyone else that can try em to test? I had several friends trip on the cubes I got and all had similar experiences (on much lower doses) and a couple that weren't very sure (novices at tripping).

I never grew my own so I can't comment on the spores try more if you don't have anyone else to test. Personally for dried cubes I like at least 5-6 for a heroic dose.

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OfflineJanus62
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Re: Can't seem to "trip" [Re: BasicTek] * 1
    #28684571 - 03/02/24 11:39 PM (3 months, 25 days ago)

Northerner's post at https://www.shroomery.org/forums/showflat.php/Number/28117277 covers a lot of the potential reasons.

In my case, when I tried my first couple of grows I got pretty much nothing.  I microdosed whilst titrating down SSRIs, but it took months for the effects of the SSRIs to finally fade.

It might be worth trying growing some Natalensis too.  They're almost as easy as cubes and were certainly my 'breakthrough', giving a really heavy hit from 3g dry.


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๐Ÿ…ƒ ๐Ÿ„ด ๐Ÿ„ฐ ๐Ÿ„ผ    ๐Ÿ„ฒ ๐Ÿ„ป ๐Ÿ„ธ ๐Ÿ„ฝ ๐Ÿ„ถ ๐Ÿ…† ๐Ÿ… ๐Ÿ„ฐ ๐Ÿ„ฟ

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Offlinebling
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Re: Can't seem to "trip" [Re: Janus62]
    #28684762 - 03/03/24 06:59 AM (3 months, 25 days ago)

I've not had this problem dosing mushrooms I grew they all seemed to be fairly potent.

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Offlinebullethead454
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Registered: 07/15/07
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Re: Can't seem to "trip" [Re: bling]
    #28684770 - 03/03/24 07:19 AM (3 months, 25 days ago)

Well, I'm drying them using a heater and fan right now. I was also using a heat lamp at some point. The air temp has been around 100F using those methods. I tried 170F in the oven, but they started to turn blue fast and kind of limp (I had the oven vented during that time). So, I decided not to do that.

I can get a dehydrator, but I haven't wanted to spend the money on that yet b/c of some other life issues (was thinking about moving and leaving all my stuff behind. So, to keep buying shit didn't make much sense).

I can try fresh. I assume 10x dry for fresh (e.g. 3.5g dry = ~35g wet). Actually, most of the trips I had were from fresh mushrooms, but like I said it was around 20 years ago and they were wild.

I have someone else that can try them, but they haven't yet.

I am taking Lithium, Phentermine, Metformin, Olanzapine/Zyprexa, a multi-vitamin, just started Chantix, and something for hormones.

I am also using the PF tek on the grows I'm talking about, but I have a popcorn/coir monotub (B+) incubating/colonizing on day 7 now.

And I know they're not on the vendor list, but I have been buying spores from Spore Store since I started growing back in 2015/2016ish. I have heard a lot of bad stuff about them, but I always seem to get my order.

This grow I'm on the 2nd flush of Ecuador and S. African Transkei.

Edited by bullethead454 (03/03/24 07:40 AM)

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OfflineSkydoggy
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Re: Can't seem to "trip" [Re: bullethead454] * 1
    #28684793 - 03/03/24 08:07 AM (3 months, 25 days ago)

I believe that there is some risk associated with the combination of psilocybin and lithium.  Iโ€™d encourage you to read a few articles about this.

https://psychedelichealth.co.uk/2021/08/13/mixing-psychedelics-with-lithium-poses-significant-risk-of-seizures/

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OfflineNeurotech
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Re: Can't seem to "trip" [Re: Skydoggy] * 2
    #28684819 - 03/03/24 08:24 AM (3 months, 25 days ago)

Olanzapine has been used to bring people down from tripping. Any of the drugs in that class will reduce or prevent a psychedelic experience. Additionally, I would think that the condition that you need olanzapine for might be one that requires extra caution in terms of the risk with psychedelics.

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Offlinebullethead454
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Re: Can't seem to "trip" [Re: Neurotech]
    #28684830 - 03/03/24 08:34 AM (3 months, 25 days ago)

I am bi-polar and have manic episodes where I can become psychotic and/or paranoid schizophrenic. However, that's usually when I've stayed up for a day or more, which I don't do anymore.

I have had these conditions for about 20 years now as well.

I assume I would want to not take my meds on the day I want to trip, but these meds can build up in the body and would take a while to deplete.

I don't mind taking the risks, b/c they seem minimal. I used to drink heavily every day for many years, but I stopped that now 3+ years sober. The risks for drinking seem much higher to me.

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Onlinetree frog
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Re: Can't seem to "trip" [Re: Neurotech] * 1
    #28684851 - 03/03/24 08:59 AM (3 months, 25 days ago)

Quote:

Neurotech said:
Olanzapine has been used to bring people down from tripping. Any of the drugs in that class will reduce or prevent a psychedelic experience. Additionally, I would think that the condition that you need olanzapine for might be one that requires extra caution in terms of the risk with psychedelics.




Yup, it's an inverse agonist for the 5ht2a receptor.  Meaning, it's already occupying those receptors and stabilizing the inactive state (so, psilocybin both has to compete to occupy the receptor and the receptors don't want to activate even if it does).

It also has a long half life (33 hours).  Meaning, it builds up in your system over time and would take several weeks to clear (more with tapering) and possibly several more for the receptors to normalize.


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Edited by tree frog (03/03/24 09:02 AM)

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Offlinebullethead454
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Registered: 07/15/07
Posts: 100
Last seen: 1 month, 23 days
Re: Can't seem to "trip" [Re: tree frog]
    #28684860 - 03/03/24 09:11 AM (3 months, 25 days ago)

Quote:

tree frog said:
Quote:

Neurotech said:
Olanzapine has been used to bring people down from tripping. Any of the drugs in that class will reduce or prevent a psychedelic experience. Additionally, I would think that the condition that you need olanzapine for might be one that requires extra caution in terms of the risk with psychedelics.




Yup, it's an inverse agonist for the 5ht2a receptor.  Meaning, it's already occupying those receptors and stabilizing the inactive state (so, psilocybin both has to compete to occupy the receptor and the receptors don't want to activate even if it does).

It also has a long half life (33 hours).  Meaning, it builds up in your system over time and would take several weeks to clear (more with tapering) and possibly several more for the receptors to normalize.




Well, I guess I'm just wasting my time and money then. Kind of sucks. I don't want to go against my doctors, but maybe I should try staying off the Olanzapine for a month or more before I try again. We've already reduced the dosage since I started, and I only started taking it maybe a year ago. So, taking myself off isn't a huge risk.

Thanks for all the feedback.

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OfflineNaraz
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Registered: 11/23/23
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Re: Can't seem to "trip" [Re: bullethead454]
    #28684984 - 03/03/24 11:23 AM (3 months, 25 days ago)

I seem to be getting better here with tripping

My first few didn't work but it seems to be working better now


I started fasting from my meds(I take adhd stuff but no SSRIs) and while I'm light headed and weak, I realized that just makes the trip even better lol

Another thing I started doing in general is digestive enzymes. I have issues being tolerant of just normal meds so I wonder if maybe there is something I'm missing to help me disgest things right

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OnlineNorthernerM
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Re: Can't seem to "trip" [Re: Skydoggy] * 2
    #28685232 - 03/03/24 02:56 PM (3 months, 25 days ago)

Quote:

Skydoggy said:
I believe that there is some risk associated with the combination of psilocybin and lithium.  Iโ€™d encourage you to read a few articles about this.

https://psychedelichealth.co.uk/2021/08/13/mixing-psychedelics-with-lithium-poses-significant-risk-of-seizures/



Absolutely this. Lithium is one of the few drugs where psilocybin has significant contraindications.

Really you need to ask yourself whether all these risks are worth it OP.


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The nearest we ever come to knowing truth is when we are witness to paradox.

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Offlinebullethead454
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Registered: 07/15/07
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Last seen: 1 month, 23 days
Re: Can't seem to "trip" [Re: Northerner]
    #28686052 - 03/04/24 10:18 AM (3 months, 24 days ago)

Quote:

Northerner said:
Quote:

Skydoggy said:
I believe that there is some risk associated with the combination of psilocybin and lithium.  Iโ€™d encourage you to read a few articles about this.

https://psychedelichealth.co.uk/2021/08/13/mixing-psychedelics-with-lithium-poses-significant-risk-of-seizures/



Absolutely this. Lithium is one of the few drugs where psilocybin has significant contraindications.

Really you need to ask yourself whether all these risks are worth it OP.




I've been taking mushrooms while on Lithium for the past 8 years. So, that is why I don't have any serious concerns about it. I'm not saying something couldn't happen, but it is highly unlikely.

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Invisibleloladoreen
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Re: Can't seem to "trip" [Re: bullethead454]
    #28686063 - 03/04/24 10:30 AM (3 months, 24 days ago)

https://genesight.com/product/

Find out what you need to take and see if you can get off some of what you are taking.
Or
You may be taking what you need and nothing needs to change.

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Onlinetree frog
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Re: Can't seem to "trip" [Re: bullethead454]
    #28686116 - 03/04/24 11:21 AM (3 months, 24 days ago)

Quote:

bullethead454 said:
Quote:

Northerner said:
Quote:

Skydoggy said:
I believe that there is some risk associated with the combination of psilocybin and lithium.  Iโ€™d encourage you to read a few articles about this.

https://psychedelichealth.co.uk/2021/08/13/mixing-psychedelics-with-lithium-poses-significant-risk-of-seizures/



Absolutely this. Lithium is one of the few drugs where psilocybin has significant contraindications.

Really you need to ask yourself whether all these risks are worth it OP.




I've been taking mushrooms while on Lithium for the past 8 years. So, that is why I don't have any serious concerns about it. I'm not saying something couldn't happen, but it is highly unlikely.




But it might be the antipsychotic that's preventing the drug interaction between the lithium and the psychedelics. If the antipsychotic is blocking the 5Ht2a receptor and it's this receptor that's interacting with the lithium, then taking the antipsychotic out of the equation might give you seizures when you trip.

And all of that said it could be your drying method.  In addition to anything the drugs you're on are doing which they are blocking the effects to some degree for sure.  As well as potentially having dangerous drug interactions. Your drying method isn't great and I think that's why someone suggested trying some fresh.  And it could just be your grow, inoculated some spores for a buddy and those mushrooms were all super weak consistently so I don't know.


--------------------

Edited by tree frog (03/04/24 11:30 AM)

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Offlinebullethead454
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Re: Can't seem to "trip" [Re: tree frog]
    #28686385 - 03/04/24 04:34 PM (3 months, 23 days ago)

Quote:

tree frog said:

But it might be the antipsychotic that's preventing the drug interaction between the lithium and the psychedelics. If the antipsychotic is blocking the 5Ht2a receptor and it's this receptor that's interacting with the lithium, then taking the antipsychotic out of the equation might give you seizures when you trip.

And all of that said it could be your drying method.  In addition to anything the drugs you're on are doing which they are blocking the effects to some degree for sure.  As well as potentially having dangerous drug interactions. Your drying method isn't great and I think that's why someone suggested trying some fresh.  And it could just be your grow, inoculated some spores for a buddy and those mushrooms were all super weak consistently so I don't know.




I can understand why you say that, but I only started the antipsychotic about a year ago. I don't really want to get off the Lithium, because if something psychotic happens to me I can always fall back on taking my meds.

I should see how someone else reacts to them to get a real sense of what's going on.

I tried 11.5g fresh (~1.2g dry) yesterday while having abstained from the olanzapine for a day, but nothing still. I think I have to wait about a month of abstaining from it, based on what has been said already.

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OfflineBardy
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Re: Can't seem to "trip" [Re: bullethead454] * 1
    #28686512 - 03/04/24 05:48 PM (3 months, 23 days ago)

Only saying this because I donโ€™t think itโ€™s been said yet in this thread, but if youโ€™re the type of person who can have psychotic episodes off your meds then mushrooms might not be good for you. Just putting that out there, Iโ€™m sure youโ€™ve already considered this.

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Onlinetree frog
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Re: Can't seem to "trip" [Re: bullethead454]
    #28686656 - 03/04/24 08:02 PM (3 months, 23 days ago)

Quote:

bullethead454 said:
I should see how someone else reacts to them to get a real sense of what's going on.




I thought that might be the case with the lithium, still be careful.  There are a lot of factors that can go into seizure thresholds that can sneak up on you and it not happening yet doesn't mean it won't.

And, I think what I quoted is a smart next step.


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