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Offlineeve69
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Registered: 04/30/03
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Re: Looking for opinions and insight on my semi-"intense" trip [Re: redgreenvines]
    #28596601 - 12/24/23 01:23 PM (1 month, 3 days ago)

shrooms work on 5ht1a 5ht2a serotonin receptors also the other monoamines dopamine and norepinephrine.  the 5hts work antagonistically - the 2 receptor downgrades the 1 receptor, at first. in the same way that ssri drugs take a month to work because of that downgrade.it must become desensitized. so shrooms happen very quickly though so you experience really too much to make sense of and the flood of norephinephrine makes you very very wide awake and so the subtle brain chages are inescapable.


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