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Tylerd222
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1st Time ? And SSRI discontinuation 2
#28275811 - 04/13/23 12:17 PM (9 months, 11 days ago) |
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After watching "How to change your mind" on Netflix I decided I wanted to try shrooms for the first time at 40yo. To do this I decided to grow them myself. I read tons and successfully got my first flush of GT. It weighed 250g before dehydrating. I used an air fryer that has a dehydration feature. I did 8 hours at 120f and then another 3 at 125f which made everything cracker dry. The dry weight was 27g. I then used a food processor and pureed them. There were still some stems that wouldnt puree so I dumped it all on a a cutting board and chopped it up the best I could. I then put them in a plastic bag.
I then immediately weighed out 2g poured it in some pineapple juice and drank it all. T+90m no effects, tried something similar to lemon tek just using lime juice with another 2g. T+4 hours from start- still nothing. (And I was trying really hard lol. I was relaxed, had a good set+setting, listen to a bunch of psychedelic music, watch "trippy" videos on YouTube, went outside, I even tried not thinking about it and just went on with my day) T+5h took 3 grams, lime tek again T+7h still nothing, decided to try another 3g because at this point I was getting super disappointed.
Long story short after consuming 10g between 11am and 6pm I never felt anything.
I knew SSRIs effected psilocybin but never imagined it would completely block it! I've been taking 40mg of citalopram for years. Does anyone have experience with how long they had to be off citalopram to be able to experience psilocybin? The half life is 36 hours and from what I read it would be completely out of my system 7.3 days after the last dose. That just seems too good to be true and I'm wondering for those of you that have done this what was your experience?
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goldenboy56
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Re: 1st Time ? And SSRI discontinuation [Re: Tylerd222]
#28277581 - 04/14/23 03:08 PM (9 months, 10 days ago) |
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Thats quite odd. I take ssri and while it may block it a little i def would still be tripping balls after one gram .
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Northerner
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Re: 1st Time ? And SSRI discontinuation [Re: goldenboy56] 1
#28278279 - 04/15/23 02:26 AM (9 months, 9 days ago) |
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It's not uncommon for SSRIs to completely block psilocybin. It depends on the sari, the length of use, your personal neurochemistry and other things.
My wife was immune to mushrooms when taking escitalopram but LSD still worked on her. Now she is taking fluoxetine and can trip on shrooms. Years have passed though, her chemistry is not the same. Something else to note here though is doses of 300mg and above were triggering anxiety and aggression for her until her system got used to experiencing having serotonin again.
Also, taking more and more shrooms over hours is just a waste. Tolerance develops over the first hour or so and the effect of any taken after that is significantly reduced.
I've given someone in SSRIs 15g of subs over an hour though, which is about the same as 30g of cubes, and they felt little more than a mild buzz. It's not uncommon.
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The nearest we ever come to knowing truth is when we are witness to paradox.
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Tylerd222
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Re: 1st Time ? And SSRI discontinuation [Re: Northerner]
#28282014 - 04/17/23 12:10 PM (9 months, 7 days ago) |
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Thanks for the reply. I continued to read other posts and articles here and it seems like in general SSRI meds block the tripping effects but may allow some positive mood help.
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Shuffalo
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Re: 1st Time ? And SSRI discontinuation [Re: Tylerd222]
#28286324 - 04/20/23 04:00 AM (9 months, 4 days ago) |
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Hello! I've been taking paxil (20mg) for around two years, daily. Panic disorder, anxiety, reactive depression. That's my first trip: https://www.shroomery.org/14945/A-Mind-Bending-Adventure
My experience definitely differs from yours, and I cannot be a valid example of psychedelics usage, but as a rule of thumb and from what I've read many times on the Internet, you gotta eat much more than the regular person. If heroic dose for a regular is 5-6, for you it might be 15 or even 20 gram dry. It might be less too, because it's always a roulette with potency, your own mood, SSRI in your system etc.
It is already hard even for general folk to get a steady dose (numerous reports of people who ate their "normal" entertainment dose but unknowingly got into something more than they bargained for), for people who take SSRIs it's much more harder.
For now I'm slowly getting off my SSRI, by gradually reducing the dose (1/2 of pill, then 1/4, then no pill at all) while doing microdosing daily. From 16th of April I've cancelled the SSRIs altogether. So far having somewhat mild withdrawal symptoms even considering that I'd been cancelling it very gradually.
Around 300-400mg daily, #2 capsules. It's hard to estimate the exact fill of capsules because I have no equipment so did everything manually and by hand, so the contents of capsules might differ a lot.
Psylo definitely helps, but I have mood swings, anxiety and slight panic attacks — surely it's something to work with for a long time after. Good things is that without paxil I actually started FEELING something. On paxil it felt like living your life behind a glass screen: you don't get depressed or anxious (much) but you also don't get to be happy, angry, affectionate etc.
Upd some hours later. One more thing: if you decide to ween off ssri, do it gradually and very slowly. Withdrawal syndrome will make you hate your life because how miserable and broken you will feel: google the ssri discontinuation, there are many helpful tips and relatable experience. And one more — don’t drop your SSRI because you want shrooming. Drop them only if you and your psychiatrist recognize that you will be better off them.
Edited by Shuffalo (04/20/23 03:00 PM)
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Tylerd222
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Re: 1st Time ? And SSRI discontinuation [Re: Shuffalo]
#28287436 - 04/20/23 09:53 PM (9 months, 3 days ago) |
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Thanks for the post! Tons of great thoughts. I was kinda thinking 10 to 15g might be what I need too just scared because I don't want to have a bad first trip. I've been thinking I might obtain some emergency xanax to take if it finally worked. The crazy thing about all this is that I've been taking these medications so long that I don't even think I need them anymore. The only reason I've continued taking them for the last 10 years or so is because of SSRI discontinuation/withdrawal. I'm on about the same timeline as you are for getting off SSRI. Wanting to take Mushrooms gave me a purpose to get off. I tapered to half a pill for about five days, quarter pill for five days, eighth pill for three days and have now had none for 4 or 5 days. I read and found that fish oil pills are supposed to help with the brain zaps (which is the only symptom I get) and I'd say its reduced them by 80 to 90%. I started taking them 3 or 4 days ago. 2000mg that include 600mg of omega 3 I also found that understanding what brain zaps are made it easier too. (Think about how a kid might get scared from a loud thunderstorm but an adult understands what it is and isn't scared) Lastly, I've also been wondering if the macrodosing I've been doing has been doing something with the serotonin making the SSRI withdrawal easy.
I took 3.5g followed by 3.5g at T+1:00 yesterday and would say I was probably at a 2 out of 10 for intoxication. I was watching TV and noticed more texture and colors were a little more vivid (but nothing that couldn't be done by adjusting the sharpness and color settings on the TV)
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Shuffalo
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Re: 1st Time ? And SSRI discontinuation [Re: Tylerd222]
#28287610 - 04/21/23 04:43 AM (9 months, 3 days ago) |
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Even in minuscule doses, it seems to help with withdrawal drawbacks. All in all, SSRI and shrooms influence serotonin levels, so it is natural that discountinuation+shrooms should be at least little bit more manageable than the flat discontinuation.
I, for one, have various mild issues with it: irregular random dizziness, brain fog, sometimes pain in various random bodyparts, nausea (rare one) and a humongous increase in appetite. I wonder what would it feel if I hadn't been microdosing.
If I were you I would wait at least one or even two weeks with normal, trip doses. Let the SSRI leave your body, and don't forget that it can turn out much more than you bargained the mush for. Psychedelics can make or break your mind in various dosages.
Edited by Shuffalo (04/21/23 04:44 AM)
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wizardsjeffery
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Re: 1st Time ? And SSRI discontinuation [Re: Shuffalo]
#28287815 - 04/21/23 08:06 AM (9 months, 3 days ago) |
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My girlfriend is on mood stabilizers, 2.5g gave her just a very light high. Same dose to me, weighing a hundred pounds more had me good.
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Tylerd222
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Re: 1st Time ? And SSRI discontinuation [Re: Tylerd222]
#28287990 - 04/21/23 10:36 AM (9 months, 3 days ago) |
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Yep I think smartest would be to wait a week or two and try some from the second flush. I'll keep you guys updated!
Before I even started growing I was tapering off ADHD stimulants. I don't think I really have ADHD, maybe but the stimulants just allow me to accomplish more during a day. I think once I'm off everything I'm going to honestly retest myself. I couldn't find any reports of stimulants blocking psilocybin, have u seen any?
How about Buorenorphine/Naloxone? From what I've read that work on dopamine.
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Shuffalo
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Re: 1st Time ? And SSRI discontinuation [Re: Shuffalo]
#28303694 - 05/02/23 03:35 PM (8 months, 23 days ago) |
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How's it going for you, friend?
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Cubes2gourmet


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Re: 1st Time ? And SSRI discontinuation [Re: Shuffalo]
#28303704 - 05/02/23 03:43 PM (8 months, 23 days ago) |
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My wife has mild trips taking sari and 2 grams
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MadSeasonStudent
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Re: 1st Time ? And SSRI discontinuation [Re: Cubes2gourmet]
#28304632 - 05/03/23 08:50 AM (8 months, 22 days ago) |
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I was on SSRI medication for a few years. And I took 10 hits of LSD and nothing happened. This other medication I was taking I stopped taking for about 6 days and took 3 drops of lsd and it worked just fine. My friend he’s on Lexapro and says he can do psychedelics and breaks through just fine. I’m good without the medication anyways. I usually take -1-2 drops every 3rd day. I have bad migraines and this really seems to work well for what I need it to do.
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BlakkSkrollz
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Re: 1st Time ? And SSRI discontinuation [Re: Tylerd222]
#28313116 - 05/09/23 06:09 PM (8 months, 15 days ago) |
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When I was on Effexor I had this problem. A mighty dose of 7g (dried) of cubes would barely get me there during that time. Now I take Zoloft & trip just fine.
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Mycoangelo13
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Re: 1st Time ? And SSRI discontinuation [Re: Tylerd222]
#28321755 - 05/16/23 09:52 AM (8 months, 9 days ago) |
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Interesting. . . a couple people I know say they do not feel anything from shrooms no matter the dosage. . . both take SSRi's. Good to know. . . thanks for the thread
-------------------- A day truly wasted is one in which you learn nothing. . .
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Tylerd222
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Re: 1st Time ? And SSRI discontinuation [Re: Mycoangelo13]
#28335620 - 05/26/23 01:54 PM (7 months, 30 days ago) |
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Just wanted to update everyone. Been off SSRIs for 6 weeks and still nothing off shrooms. I did try some LSD and have had some mild trips. Brighter colors, wavy/moving lines in stuff like wood grain. It also made me feel really happy (I think euphoric is the right term) and for a couple of the trips everything was funny. Here's a couple examples 1. Someone asked me what's the difference in the flavor of different skittles? Mind blown...is there a difference...how would you even describe that. You probably get what I'm explaining. 2. I really like drinking cold distilled water and a friend was asking me to see if I could taste the difference between tap water and distilled and I was hysterically laughing because it was so easy for me.
I was still able to function totally fine though which is either my misconception about tripping or explains how mild it was. One of the trips I was even at work and no one questioned anything I did.
I think my thought so far on tripping and SSRIs is that everyone's brain chemistry is different and each prescription you take is a variable in the tripping equation along with how your brain likes specific drugs like how mine seems to trip off LSD but not off Psilocybin.
But don't worry fellow mycologists I have 7 grain bags colonizing and one tub about to start fruiting so I'll try a mushroom trip again in about a month.
One last thing, I fully agree that one of the issues might be that I'm tying to do too much tripping too often and that could be contributing to the problem. (19 tabs of LSD total over the last month along with a 4g mush trial and 2g mush combined with 2 tabs)
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newaccounts
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Re: 1st Time ? And SSRI discontinuation [Re: Tylerd222]
#28357986 - 06/13/23 06:15 AM (7 months, 12 days ago) |
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I was on wellbutrin for four months and mirtazapine for seveb months. Quit wellbutrin 4 months before my first trip and mirtazapine exactly one month before. I did trip but suspect that my chemistry was still effected by the mirtazapine. I think depending on how long you have been on an antidepressant the longer it will take until it doesnt interfere in a trip.
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Ythan
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Re: 1st Time ? And SSRI discontinuation [Re: Tylerd222]
#28358514 - 06/13/23 02:00 PM (7 months, 12 days ago) |
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I recently came across an interesting study which confirmed that SSRIs do attenuate the effects of psilocybin, and found that they continue to do so for 3–6 months after discontinuation.
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