This article is interesting on a non cube that most who try it seem to prefer. This info on various known active compounds and the probability there are more not yet known would explain how various strains and batches of each strain, do differ in effects on individuals. Some claim that a cube is a cube differing only in levels of psilocybin and psilocin. And expectations, setting, are the reasons for any differences. This seems improbable to me. Finding the right strain grown with the right conditions to be the right medicine for each of us may take testing quite a few. Frustrating. Hoping that more states will legalize, allow people to test for what works and have valid research done. From the article: We’ve only just scratched the surface when it comes to profiling the chemical constituents of psilocybin-producing mushrooms, as evidenced by the recent detection of beta-carboline compounds in trace amounts and the recently discovered presence of various alkaloids such as baeocystin, norbaeocystin, and aeruginascin. . One study concluded that the “varied cocktail of tryptamines (serotonergic hallucinogens) in wild mushrooms could influence the medicinal effect.” Another fresh-off-the-presses research study stated that the “P. cubensis metabolome possibly contains thousands of uncharacterized compounds, at least some of which may be bioactive,” and that “our understanding of the chemical diversity of these mushrooms is largely incomplete.” Still, Psilocybe natalensis has been profiled and demonstrated antioxidant and anti-inflammatory properties. In another study, human macrophage cells were treated with magic mushroom water extracts in vitro. Four mushroom species (Panaeolus cyanescens, Psilocybe natalensis, Psilocybe cubensis, and Psilocybe cubensis A+ strain) showed anti-inflammatory effects on proinflammatory agents. There are no studies directly researching the therapeutic use of Psilocybe natalensis strains,but their anti-inflammatory effects might be helpful in some cases, such as for treatment of chronic inflammation. P. natalensis can repress the activity of cytokine proteins that initiate immune responses, such as tumor necrosis factor (TNF-α).
https://thethirdwave.co/psilocybe-natalensis-mushrooms/
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