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Offlinesmalltalk_canceled
Babnik
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Re: A note on mushrooms and potency [Re: Ashtray161] * 1
    #27508808 - 10/18/21 09:08 AM (2 years, 3 months ago)

"Wood lovers such as Psilocybe azurescens are confirmed to contain a compound called aeruginascin that may be responsible for a condition termed “woodlovers paralysis.” Trace amounts of aeruginascin.."


Maybe this part needs a update, don't we today think that aeruginascin is the good/ bad trip regulator ? Or?


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InvisiblePastywhyteMDiscord
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Re: A note on mushrooms and potency [Re: smalltalk_canceled] * 1
    #27508930 - 10/18/21 10:55 AM (2 years, 3 months ago)

I’m not sure the results on it being a good/bad trip regulator are in the can unless you have a link I could have a look at. But certainly a lot has happened in the 15 months that have passed since I wrote the OP. Hard to believe that much time has passed. I will definitely be giving the whole thing a going over soon.


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OfflineRedRH
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Re: A note on mushrooms and potency [Re: Pastywhyte] * 2
    #27618303 - 01/14/22 09:32 AM (2 years, 14 days ago)

I agree with the OP's post 100% and found it very informative.

I bought a freeze drier for my emergency food storage and am using it for my shrooms. I store the freeze dried shrooms in mylar bags sealed with an O2 absorber packet. If shrooms are like all my other freeze dried produce, then there is very little loss of nutrients and actives. I have tried both air dried and FD'd doses and can state subjectively that there is a noticeable difference in strength, but that again, is just a subjective opinion as I am not equipped to determine active amounts of compounds present. Even if one dehydrates their product, storage in mylar bags with an O2 absorber and storage temp control will go a long way in preserving the actives over time in my opinion. Light, temperature, and oxygen exposure are the factors I focus on mitigating.


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OfflineSeaSalt
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Re: A note on mushrooms and potency [Re: Pastywhyte] * 1
    #27621499 - 01/16/22 06:28 PM (2 years, 11 days ago)

This information is extremely valuable.
Both me and a friend wonder why our friends who weigh 2 to 3x our weight achieve results at .05 to 1.5 gm P. Cube & PE and we don't.
I've never ingested any psychoactive fungi in my life (I'm 60) and needed more than 2.0(dried) to achieve anything close to the effect of others. After later discussion between recipients, I found that two of us were prescribed the same anti seizure drug. One of us at 2x the strength of the other. Both of us require higher doses than those who aren't prescribed any anti-depressants or anti-seizure medication.


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OfflineSpaceBaby
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Registered: 11/01/20
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Re: A note on mushrooms and potency [Re: SeaSalt] * 1
    #27621521 - 01/16/22 06:56 PM (2 years, 11 days ago)

Quote:

SeaSalt said:
This information is extremely valuable.
Both me and a friend wonder why our friends who weigh 2 to 3x our weight achieve results at .05 to 1.5 gm P. Cube & PE and we don't.
I've never ingested any psychoactive fungi in my life (I'm 60) and needed more than 2.0(dried) to achieve anything close to the effect of others. After later discussion between recipients, I found that two of us were prescribed the same anti seizure drug. One of us at 2x the strength of the other. Both of us require higher doses than those who aren't prescribed any anti-depressants or anti-seizure medication.




You need 2HTA receptors to be abailable. SSRIs and other serotonin-targeted psych meds are blockers, e.g.cymbalta, mirtazipine/ Also calcium-channel blockers blcokd psychedlics [and erections].

Also, alcoholics require approximately a 2x dose over non-alkies. I usually do around 4g cubes to get low L2.


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OfflineLSDCubed
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Re: A note on mushrooms and potency [Re: SpaceBaby] * 1
    #27641412 - 02/01/22 06:59 PM (1 year, 11 months ago)

Did anyone try the Miraculix home test kit for Psilocybin?


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OfflineStrawberry1
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Re: Temps and Potential [Re: LSDCubed] * 1
    #27656055 - 02/12/22 06:56 AM (1 year, 11 months ago)

Following this thread :smile:


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OfflineFredbare
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Re: Temps and Potential [Re: Strawberry1] * 1
    #27666697 - 02/20/22 04:25 PM (1 year, 11 months ago)

Great information. I had an oz of dry chopped in an air tight loose 80% potency in 6 months. Oxygen exposure was the only offender. Dessicated employed..gel,coco, alcohol seem to be reliable anti oxygen seals..


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OfflineBillyboy2
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Re: A note on mushrooms and potency [Re: Pastywhyte] * 1
    #27706396 - 03/24/22 01:02 AM (1 year, 10 months ago)

Hey guys new here, I’ve just bought 7 grams of what I’ve been told are dried (subs) but I’m a little sketched out knowing that there is poisonous mushrooms that are similar and easily mixed up with, is there possibly any ways to identify subs from galerina when they are dried out? Any feedback would be greatly appreciated. Cheers


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InvisiblePastywhyteMDiscord
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Re: A note on mushrooms and potency [Re: Billyboy2] * 3
    #27706783 - 03/24/22 10:48 AM (1 year, 10 months ago)

Quote:

Billyboy2 said:
Hey guys new here, I’ve just bought 7 grams of what I’ve been told are dried (subs) but I’m a little sketched out knowing that there is poisonous mushrooms that are similar and easily mixed up with, is there possibly any ways to identify subs from galerina when they are dried out? Any feedback would be greatly appreciated. Cheers




You would be better off asking ID questions here MHID with photos of said fruits. Also it’s very different to identify dried fungi. The easy way to tell a galerina is they have brown spores so look at those. But personally I would avoid buying wild collections from people you don’t implicitly trust, especially given how easy it is to grow them.


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InvisibleTheConfluence
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Re: Temps and Potential [Re: Pastywhyte] * 1
    #27710355 - 03/27/22 09:53 AM (1 year, 9 months ago)

21 grams of fresh Cyanesence is nothing like 21 grams of fresh cubenses.


This is the best science project.


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When two people dream the same dream, it ceases to be an illusion.


Philip K. Dick
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Edited by TheConfluence (03/27/22 09:54 AM)


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Offlineamanituser
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Re: Temps and Potential [Re: TheConfluence] * 1
    #27713392 - 03/29/22 08:17 PM (1 year, 9 months ago)

Is wood lover's paralysis kind of like extreme time dilation where you feel like you were frozen in time after having not moved for like 2 seconds?


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InvisibleAshtray161
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Re: Temps and Potential [Re: amanituser] * 1
    #27716074 - 04/01/22 05:13 AM (1 year, 9 months ago)

Quote:

amanituser said:
Is wood lover's paralysis kind of like extreme time dilation where you feel like you were frozen in time after having not moved for like 2 seconds?




More like a DMT style literally cant move type of thing


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OfflineBroom
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Re: A note on mushrooms and potency [Re: Pastywhyte]
    #27798463 - 05/29/22 11:38 PM (1 year, 7 months ago)

nice post/ read. thanks


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OfflineBrownEyedMan
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Re: A note on mushrooms and potency [Re: mistermushly]
    #27873583 - 07/23/22 12:02 AM (1 year, 6 months ago)

Note: This study shows that freezing results in the greatest loss of potency. Your experience shows that there was a lot of potency in your shrooms to begin with.

Note this is a direct link to the study pdf from Oregon.gov

https://www.oregon.gov/oha/PH/PREVENTIONWELLNESS/Documents/Stability%20of%20Psilocybin%20and%20Analogs.pdf

Here’s the abstract:

Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Prague 6–Dejvice, Czech Republic
2Department of Brain Electrophysiology, National Institute of Mental Health, Klecany, Czech Republic
3Institute of Geology of the Czech Academy of Sciences, Prague 6, Czech Republic
4Nuclear Physics Institute of the Czech Academy of Sciences, Husinec, Czech Republic
5Department of Organic Chemistry, University of Chemistry and Technology Prague, Prague 6–Dejvice, Czech Republic
6Department of Experimental Neurobiology, National Institute of Mental Health, Klecany, Czech Republic
Correspondence
Martin Kuchař, University of Chemistry and Technology Prague, Technická 3, 166
28 Prague 6–Dejvice, Czech Republic. Email: martin.kuchar@vscht.cz
Funding information
Czech Academy of Sciences, Grant/Award Numbers: RVO61389005, RVO67985831; Ministry of the Interior of the Czech Republic, Grant/Award Number: MV0/VI20172020056
1 | INTRODUCTION
Psychoactive mushrooms have been used as entheogens during tran- scendental ceremonies by Mexican inhabitants, mainly by shamans, for thousands of years. Mushrooms used for religious and spiritual rituals are called “magic mushrooms.”1–3 There are many mushroom species that contain high levels of tryptamines.
  Abstract
Psilocybin, psilocin, baeocystin, norbaeocystin, and aeruginascin are tryptamines structurally similar to the neurotransmitter serotonin. Psilocybin and its pharmacolog- ically active metabolite psilocin in particular are known for their psychoactive effects. These substances typically occur in most species of the genus Psilocybe (Fungi, Strophariaceae). Even the sclerotia of some of these fungi known as “magic truffles” are of growing interest in microdosing due to them improving cognitive function studies. In addition to microdosing studies, psilocybin has also been applied in clinical studies, but only its pure form has been administrated so far. Moreover, the determi- nation of tryptamine alkaloids is used in forensic analysis.
In this study, freshly cultivated fruit bodies of Psilocybe cubensis were used for monitoring stability (including storage and processing conditions of fruiting bodies). Furthermore, mycelium and the individual parts of the fruiting bodies (caps, stipes, and basidiospores) were also examined. The concentration of tryptamines in final extracts was analyzed using ultra-high-performance liquid chromatography coupled with mass spectrometry. No tryptamines were detected in the basidiospores, and only psilocin was present at 0.47 wt.% in the mycelium. The stipes contained approx- imately half the amount of tryptamine alkaloids (0.52 wt.%) than the caps (1.03 wt. %); however, these results were not statistically significant, as the concentration of tryptamines in individual fruiting bodies is highly variable. The storage conditions showed that the highest degradation of tryptamines was seen in fresh mushrooms stored at −80C, and the lowest decay was seen in dried biomass stored in the dark at room temperature.
KEYWORDS
LC-MS, mushrooms, psilocybin, stability, tryptamines


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InvisiblePastywhyteMDiscord
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Re: A note on mushrooms and potency [Re: BrownEyedMan]
    #27873927 - 07/23/22 09:37 AM (1 year, 6 months ago)

A lot of good science being done lately. I definitely remember reading that paper when it came out and feeling that it matched my personal observations. Nice share :rockon:


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OfflineBasicjane
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Re: A note on mushrooms and potency [Re: Pastywhyte]
    #27876154 - 07/25/22 03:48 AM (1 year, 6 months ago)

This was an awesome read! Thanks for the info :smile:


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OfflineBill_Bumpskin
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Re: A note on mushrooms and potency [Re: Pastywhyte]
    #27883112 - 07/30/22 04:28 PM (1 year, 5 months ago)

I know this thread is about two years old…but thank the good lord above that someone finally said cubes aren’t just cubes, and drying in a dehydrator doesn’t degrade potency. I was so fed up with hearing this for so many years. I swear people just made stuff up tor the hell of it.


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Offlinemistermushly

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Re: A note on mushrooms and potency [Re: Bill_Bumpskin]
    #27883146 - 07/30/22 04:59 PM (1 year, 5 months ago)

Trying to decipher the scientific study BrownEyedMan posted (here) in practical application terms.

Quite a few few very significant take-aways in this study, which I hope some more scholarly person can confirm - thinking of maybe you Pasty : )

My personal approach is using a dehydrator at around 150F, storing in airtight mason Jars, and storing in the dark around 75F. Usually they are left whole but sometimes ground into a powder...

... so If I'm reading the study correctly, dried mushrooms that are stored in airtight containers will lose 75% of there potency within 15 months?
Whoah!!... that doesn't seem like it's aligned with my experience though I am far from an expert as I am more of a grower than a taker - and of course I lack the equipment and knowlege to test the compounds.

Also another interesting fact, if I'm reading it right, drying mushrooms at room temperatures ( rather than a dehydrator ) maintains more of their potency?

:whatdoyouthink:


Edited by mistermushly (07/30/22 05:52 PM)


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InvisiblePastywhyteMDiscord
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Re: A note on mushrooms and potency [Re: mistermushly] * 1
    #27883207 - 07/30/22 05:51 PM (1 year, 5 months ago)

Right off the hop I noticed they don’t discuss how they cultivated the mushrooms. Many times these studies ignore the impact of specific genetics on potency. I’ve seen more than a few that used MS syringes and even kits which of course throws all the results into doubt. The fact that they don’t say how they produced the fruits kinda makes me want to disregard everything in this study. While the names of those involved are impressive contributors in mycology, I’ve seen these kind of mistakes before from academics who are sometimes surprised to learn that their controls were less than they believed.

It sometimes irks me how the “legit” community ignores the understanding that we in the underground have known for years and years. I’m not in a position to do much of this work myself so it drives me nuts when the outcomes of such well intentioned efforts are undermined by such simple ignorance of the organism.


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