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InvisibleveggieM

Registered: 07/25/04
Posts: 17,501
Forgotten Psychedelics: What Is 2C-B?
    #27537705 - 11/10/21 10:32 AM (2 years, 2 months ago)

2C-B  :yesnod: ...

Forgotten Psychedelics: What Is 2C-B?
November 9, 2021 - Psychedelic Spotlight

4-Bromo-2,5-dimethoxyphenethylamine (also known as Nexus, Erox, or 2C-B) was synthesized by a famous American pharmacologist and psychonaut, Alexander Shulgin, in 1974.

When you think of psychedelics, substances such as LSD, psilocybin, or perhaps even MDMA, immediately come to mind. The 1970s, however, was a golden age of discovery in the pharmacological world of psychedelics, leading to 2C-B.

The substance is unique: it’s understudied, its effects are unlike other psychedelics, and it’s often unheard of. Here we’ll explore the history, the effects, and the potential therapeutic application, of this unique psychedelic.

Tripping Through Time: The History of 2C-B

4-Bromo-2,5-dimethoxyphenethylamine (also known as Nexus, Erox, or 2C-B) was synthesized by a famous American pharmacologist and psychonaut, Alexander Shulgin, in 1974.

In his lifetime, Shulgin was responsible for the synthesis and discovery of over 230 novel psychoactive compounds. More than that, he was a devout psychonaut, exploring the realms of his consciousness with all of his pharmacological creations (he allegedly tripped some 10,000 times). However, 2C-B was up there as one of Shulgin’s most preferred psychedelic journeys.

In 2003, he told the Center for Cognitive Liberty and Ethics, “[2C-B] is, in my opinion, one of the most graceful, erotic, sensual, introspective compounds I have ever invented. For most people, it is a short-lived and comfortable psychedelic, with neither toxic side-effects nor next-day hang-over.”

Due to these relatively comfortable effects, 2C-B found its favor in the recreational club scene of the ’80s and ’90s. After MDMA became a Schedule I substance in the US, many people migrated to the use of 2C-B, which was relatively unknown by the DEA at the time. It was packaged and sold in sex shops, head shops, and some nightclubs from the mid-’80s to the early ’90s. Whilst it was primarily used for partying, these establishments advertised that “it would alleviate impotence, frigidity and diminished libido”.

The legal use of 2C-B came to a stop in 1995, when the DEA classed it as a Schedule I substance in the US.

Tripping on This Forgotten Psychedelic

An average dose of 2C-B is somewhere in the range of 10 and 25mg. Users will most often orally ingest 2C-B, either in a pill or ‘bomb it’ (wrapping it in a cigarette skin or piece of toilet paper) in powder form.

What makes the effects of 2C-B particularly interesting is the chemical crossroads it finds itself in. It’s classed as a phenethylamine, a chemical cousin of mescaline. Some effects are therefore similar to classic psychedelics, like LSD; open-eye visuals are commonplace, with patterns and outlines of shapes moving and undulating throughout the trip.

However, the substance also has a stimulating quality, with certain sensual aspects emerging (as Shulgin described). Much like MDMA, 2C-B takes on entactogenic properties, increasing empathy, heightening tactile sensations, and inducing euphoria.

This mish-mash of psychedelic and entactogenic effects make a 2C-B trip quite unique in its nature when compared to other well-known psychoactive substances. Some classify the effects as a cross between LSD and MDMA.

2C-B as Therapy?

The golden age of psychedelic research, the 1950s and ’60s, saw a huge number of clinical studies being conducted. However, the infamous ban on psychedelics in 1971 shut down the burgeoning field of psychedelic research. As 2C-B wasn’t even created by this time, this left no room for the drug to be officially investigated as a therapeutic substance.

The ban on psychedelics, however, led to a broad network of underground psychedelic therapy emerging. While little is publicly known about the ongoings of this underground world, Dr. Ben Sessa, a psychedelic researcher, published a paper about his conversations with the German psychiatrist Friederike Fischer. Dr. Fischer and her husband frequently used 2C-B in combination with MDMA for therapeutic purposes. They treated some 97 clients in total, until the couple’s arrest in 2009.

The psychotherapeutic work conducted by the pair did not lead to any clinical conclusions about the use of 2C-B in combination with MDMA, as no quantitative data was collected about clients’ progress. However, outcomes of the therapeutic work were “overwhelmingly positive. There were no serious adverse reactions to the substances, no psychoses, no hospitalizations, and no suicides of any clients who were actively undergoing psycholytic therapy.”

Despite this, we can’t be sure of how effective this forgotten psychedelic is on specific mental health conditions (the 97 clients of Fischer’s had a range of issues). As the therapeutic effects of 2C-B are massively understudied, more controlled research should be conducted to establish the positive effects of this unique psychedelic.


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OfflineWhoManBeing
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: veggie]
    #27537787 - 11/10/21 11:36 AM (2 years, 2 months ago)



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Hip, hip... WhoRAy!!!

Eye was thinking the other day...  ahh, thinking never done me no good.



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OfflineLittleman

Registered: 10/01/06
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: WhoManBeing] * 1
    #27537947 - 11/10/21 01:38 PM (2 years, 2 months ago)

yeah.... 'forgotten'  :lol:


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"Well Right after the 4th hit he was so far gone he puked all over him self. He had no clue that he threw up on him self and was finger painting in it on his stomach."
- Mudnpool

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Subaeruginosa-Weraroa-Semilanceata
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Invisibletyrannicalrex
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: veggie]
    #27537954 - 11/10/21 01:45 PM (2 years, 2 months ago)

I still have never tried it! I want to so badly!


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InvisibleInvisible_Woe

Registered: 05/25/07
Posts: 11,707
Loc: Mabase
Re: Forgotten Psychedelics: What Is 2C-B? [Re: tyrannicalrex]
    #27538060 - 11/10/21 03:16 PM (2 years, 2 months ago)

Funny way for one to realize their time is no longer. Back in my day 2-cb was novel :oldman: :lol:


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These are not the answers you should be questioning.


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Invisibletyrannicalrex
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: Invisible_Woe] * 1
    #27538068 - 11/10/21 03:25 PM (2 years, 2 months ago)

I remember seeing it at a gas pipe head shop in dallas way back in the 90's. It was sold a "shrooms" and was put on regular button mushrooms. Then it was something like "Bees" or something like that and it was OTC, then went under the counter, then gone. I had tried that herbal "E" shit and was really disappointed so I never tried the B's.:sad:


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OfflineSugabearcrisp
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: Invisible_Woe]
    #27538071 - 11/10/21 03:30 PM (2 years, 2 months ago)

2c-b is awesome. Psychedelic champagne, all sparkle and neon :awehigh:

It also does make sex pretty awesome at a 5-7mg  dose, which is why it was sold as such.


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InvisibleButtFace
Registered: 08/06/08
Posts: 1,546
Re: Forgotten Psychedelics: What Is 2C-B? *DELETED* [Re: Sugabearcrisp]
    #27538153 - 11/10/21 04:40 PM (2 years, 2 months ago)

Post deleted by ButtFace

Reason for deletion:


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OfflineSugabearcrisp
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: ButtFace] * 2
    #27538245 - 11/10/21 05:44 PM (2 years, 2 months ago)

Saying LSD is naturally occurring is a stretch, you'd only experience ergotism from the natural source.

Further 2c-b can be synthed from natural anise oil and probably other natural sources https://chemistry.mdma.ch/hiveboard/novel/000475637.html

Anyways what the article gets wrong is that 2c-b's stimulant effect is not really surprising as the phenethylamine class includes amphetamines and MDxx. Such a wild class of drugs, with potency's that vary by factors of 10.


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OfflineFailboat
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: Sugabearcrisp]
    #27538316 - 11/10/21 07:12 PM (2 years, 2 months ago)

I tried to get some off the silk road once. Never showed and I got 50% refund which was just enough for a sheet of 25c-nbome :crazy2:


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InvisibleInvisible_Woe

Registered: 05/25/07
Posts: 11,707
Loc: Mabase
Re: Forgotten Psychedelics: What Is 2C-B? [Re: tyrannicalrex]
    #27538444 - 11/10/21 09:07 PM (2 years, 2 months ago)

Quote:

tyrannicalrex said:
I remember seeing it at a gas pipe head shop in dallas way back in the 90's. It was sold a "shrooms" and was put on regular button mushrooms. Then it was something like "Bees" or something like that and it was OTC, then went under the counter, then gone. I had tried that herbal "E" shit and was really disappointed so I never tried the B's.:sad:




"E" as in 2c-e?

Ime 2c-e and 2c-i were quite similar. 2c-b being a lot less intense and far superior. 2c-e is very much worth doing.

Also.. don't snort 2c-e or -i :mmmkay:


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Invisibletyrannicalrex
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: Invisible_Woe]
    #27538468 - 11/10/21 09:29 PM (2 years, 2 months ago)

"herbal ecstasy" it had a big E on the box. I already snorted 2c-e a long time ago, yeah it was very painful, but subsided quickly. I only snorted it once to experience it. I still have a half gram somewhere. Didn't like 2c-I.


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InvisibleHolybullshit
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: ButtFace]
    #27538816 - 11/11/21 05:56 AM (2 years, 2 months ago)

Depending on which synthetic's you are talking about, you aren't "buggering" yourself up any more with them than you would with something "natural". A molecule is a molecule, it doesn't know it's inside a mushroom or a cactus.


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OfflineFailboat
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: Holybullshit]
    #27539203 - 11/11/21 12:16 PM (2 years, 2 months ago)

That's cool if it's 100% pure... and then still a lot of shit shouldn't be snorted raw... you know what, don't snort things.

Funny that you should describe the 2c-b,e,i that way because it's just like that with the nbome series :rofl: the suspected 25i-nbome gave me an eye twitch for a while I swear. 25c-nbome was much more mild and developed tolerance quuck personally.


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Invisibletyrannicalrex
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: Failboat]
    #27539301 - 11/11/21 01:25 PM (2 years, 2 months ago)

I snort 3fa and 2fa when I do it.:shrug:


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OfflineFailboat
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: tyrannicalrex]
    #27539448 - 11/11/21 03:05 PM (2 years, 2 months ago)

Do you dissolve it first? I would advocate intranasal mist over insufflation of powders. I'm on a no fun zone ride and so I reccomend the healthy choice of not snorting things.

I mean if we're gonna get wild let's fucking do it man, ya know.:smoker: But no needles for me!


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Invisibletyrannicalrex
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: Failboat]
    #27539513 - 11/11/21 04:06 PM (2 years, 2 months ago)

no, just small bumps maybe 5-10mg at a time. I use a saline rinse after the night is done though.


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OfflineFailboat
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: tyrannicalrex]
    #27539520 - 11/11/21 04:13 PM (2 years, 2 months ago)

Why not just do regular amp?


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Invisibletyrannicalrex
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: Failboat]
    #27539544 - 11/11/21 04:30 PM (2 years, 2 months ago)

Short time it actually works and less intense. I can sleep later on, plus I don't fuck with speed freaks/speed anymore so those rc's are right where I like it. I originally bought them to enhance mdma or 5-mapb.


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OfflineschmutzenS
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: tyrannicalrex]
    #27540523 - 11/12/21 12:46 PM (2 years, 2 months ago)

Ketamine and 2fdck both make me sneeze like crazy followed by a bloody nose a couple days later.  The nasal mist sounds nice but doubt that I could the dosages that I want up there.  Done with needles.  Might go to strictly boofing. :shrug:


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OfflineFailboat
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Re: Forgotten Psychedelics: What Is 2C-B? [Re: schmutzen] * 1
    #27540583 - 11/12/21 01:29 PM (2 years, 2 months ago)

Sounds like you should stop doing drugs and go see an ENT. Septum perforations aren't fun and there's all kinds of other more common problems you might be suffering from that can be treated.

I used to snort 3-10g ket daily. Purity varies even though some people claim it's not cut. :rolleyes: Anyway I wish I had used nasal solutions. You can make it quite concentrated and it works more efficiently so less is more.


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