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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: falcon]
    #27422325 - 08/10/21 09:28 AM (2 years, 6 months ago)

Which you only would do in winds under a certain mph and only if the humidity is above a certain percentage. Otherwise you risk crowning and an out of control fire.


That I do know about from being on controlled burns.


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[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: bodhisatta] * 1
    #27422328 - 08/10/21 09:32 AM (2 years, 6 months ago)

Quote:

bodhisatta said:
Paradox your argument isn't rational at all as well you're still confusing drug resistance with vaccines. There's no vaccine resistance there's antibody resistance. If the virus mutates enough that the antibodies caused by the current vaccine no longer work we can update the vaccine. You can always make a new antibodies for new proteins. You can't always make a new antibiotic or chemical to fight bacteria or bugs.

You have failed on every level to have a meaningful point





Except the examples of viruses that develop vaccine resistance I showed you. In the public health outreaches I showed you the response was heavy vaccination in at risk population either because of exposure or because of poor health. No one would recommend everyone get a flu shot. Oh but that's a rhinovirus. It also happens win west Nile and dengus, which is why we don't have 100% vaccination rate recommendations for them, despite having vaccines for them.

Yes and this is a novel coronavirus, not just a regular virus.

I have a very meaningful argument.i would say it is you without a meaningful argument but you're not arguing with me you're just insulting me.


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[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


Edited by paradoxlost (08/10/21 09:33 AM)


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InvisiblefeeversM
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: paradoxlost]
    #27422340 - 08/10/21 09:43 AM (2 years, 6 months ago)

Quote:

paradoxlost said:
No one would recommend everyone get a flu shot. Oh but that's a rhinovirus.




Are you attempting a HamHead impersonation?


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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: feevers]
    #27422383 - 08/10/21 10:13 AM (2 years, 6 months ago)

https://science.sciencemag.org/content/early/2021/05/19/science.abh1139.full


Quote:

While several different COVID-19 vaccines have been deployed globally, a major concern is the emergence of antigenically distinct SARS-CoV-2 variants of concern (VOCs). In particular, the B.1.1.7 lineage that arose in the UK (1) and quickly became dominant, B.1.351 (also known as 501Y.V2) lineage in South Africa (2), B.1.1.28 lineage (and its descendant B.1.1.28.1, aka P.1/501Y.V3) in Brazil (3), and B.1.232/B.1.427/B.1.429 (aka CAL.20C and CAL.20A) in the United States (4) have raised serious questions about the nature, extent and consequences of antigenic drift in SARS-CoV-2. In the receptor-binding site (RBS) of the spike (S) protein receptor-binding domain (RBD), the B.1.1.7 lineage has acquired an N501Y mutation, B.1.351 and P.1 lineages share this mutation along with K417N/T and E484K, whereas the California variants have an L452R mutation that is also present in the Indian variant B.1.617 with E484Q (5). E484K has also been detected in a few B.1.1.7 genomes (1) (Fig. 1A). We therefore investigated the structural and functional consequences of such mutations on neutralizing antibodies (nAbs) isolated from COVID-19 convalescent patients, and their effect on angiotensin-converting enzyme 2 (ACE2) receptor binding.







Literally talking about how the different vaccines in different areas will require different strategies for future vaccine development regionally.


--------------------
[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: feevers]
    #27422385 - 08/10/21 10:13 AM (2 years, 6 months ago)

Quote:

feevers said:
Quote:

paradoxlost said:
No one would recommend everyone get a flu shot. Oh but that's a rhinovirus.




Are you attempting a HamHead impersonation?





Are attempting an emperor's new clothes impression?


--------------------
[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


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Offlinemorrowasted
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: paradoxlost]
    #27422392 - 08/10/21 10:17 AM (2 years, 6 months ago)

I mask up now in public despite being vaccinated


I don't know anyone vaccinated who has gotten so sick they had to be hospitalized but more and more vaccinated are definitely coming down with covid


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OfflinemndfreezeMDiscordReddit
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: morrowasted] * 2
    #27422400 - 08/10/21 10:23 AM (2 years, 6 months ago)

I never stopped wearing my mask when I rarely go out.  If the last 5 years has taught me anything, it's that people can't be trusted to make good decisions and are selfish assholes. So fuck em.


--------------------
Nothing says love like grannies prolapsed anus!

quote]Urb said:
I know... Its fucked up... Ill fix it minyana..[/quote]


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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: morrowasted]
    #27422465 - 08/10/21 10:58 AM (2 years, 6 months ago)

Quote:

morrowasted said:
I mask up now in public despite being vaccinated


I don't know anyone vaccinated who has gotten so sick they had to be hospitalized but more and more vaccinated are definitely coming down with covid





Good man.

I've known a few people who got sick from the vaccine but they were already in denial of their closeness to death so like I don't consider that anything.


--------------------
[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


Edited by paradoxlost (08/10/21 11:04 AM)


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InvisiblebodhisattaMDiscordReddit
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: paradoxlost]
    #27422509 - 08/10/21 11:32 AM (2 years, 6 months ago)

Quote:

paradoxlost said:
https://science.sciencemag.org/content/early/2021/05/19/science.abh1139.full


Quote:

While several different COVID-19 vaccines have been deployed globally, a major concern is the emergence of antigenically distinct SARS-CoV-2 variants of concern (VOCs). In particular, the B.1.1.7 lineage that arose in the UK (1) and quickly became dominant, B.1.351 (also known as 501Y.V2) lineage in South Africa (2), B.1.1.28 lineage (and its descendant B.1.1.28.1, aka P.1/501Y.V3) in Brazil (3), and B.1.232/B.1.427/B.1.429 (aka CAL.20C and CAL.20A) in the United States (4) have raised serious questions about the nature, extent and consequences of antigenic drift in SARS-CoV-2. In the receptor-binding site (RBS) of the spike (S) protein receptor-binding domain (RBD), the B.1.1.7 lineage has acquired an N501Y mutation, B.1.351 and P.1 lineages share this mutation along with K417N/T and E484K, whereas the California variants have an L452R mutation that is also present in the Indian variant B.1.617 with E484Q (5). E484K has also been detected in a few B.1.1.7 genomes (1) (Fig. 1A). We therefore investigated the structural and functional consequences of such mutations on neutralizing antibodies (nAbs) isolated from COVID-19 convalescent patients, and their effect on angiotensin-converting enzyme 2 (ACE2) receptor binding.







Literally talking about how the different vaccines in different areas will require different strategies for future vaccine development regionally.



If you read the entire article the solution is to fast track vaccination of people. And develop new vaccines as needed


--------------------
:whyyy:


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InvisiblebodhisattaMDiscordReddit
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: bodhisatta]
    #27422511 - 08/10/21 11:34 AM (2 years, 6 months ago)

Especially because the drift is happening in unvaccinated people especially immunocompromised people where the virus lingers for longer


--------------------
:whyyy:


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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: bodhisatta]
    #27422512 - 08/10/21 11:35 AM (2 years, 6 months ago)

Quote:

bodhisatta said:
Especially because the drift is happening in unvaccinated people especially immunocompromised people where the virus lingers for longer





So the drift is a thing. Cool thanks for agreeing with me. You guys are saying this doesn't happen. It clearly does.


--------------------
[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: paradoxlost]
    #27422515 - 08/10/21 11:37 AM (2 years, 6 months ago)

New question: which vaccine should I get and is it better or worse there are more then one vaccine going around


If you are a person who things in black and white, please don't answer.


--------------------
[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: paradoxlost]
    #27422523 - 08/10/21 11:42 AM (2 years, 6 months ago)

Mutations will still appear as long as the virus continues to replicate within hosts, as a matter of mere probabilities. So far, selective pressures toward the virus might have given rise to variants with a fitness advantage based on infection, replication, or transmission efficiency, although potential evasion from antibodies—like the one observed in McCarthy’s paper—might result as a by-product or due to immune pressure within an individual during chronic COVID-19. As the population becomes less naive to the virus through natural infection or vaccination, the selective pressure to escape acquired immune responses will be higher and will force the virus to find a way. Variants with antigenic drift would introduce antigenic novelty and enable reinfection, as happens with influenza A, whose hemagglutinin protein requires a very small number of mutations to evade pre-existing immunity.


https://www.nature.com/articles/s41392-021-00601-8






This would seem to indicate that so far , varients that evolved from immunocompromised and vaccinated people are more virulent or contagious


--------------------
[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: paradoxlost]
    #27422527 - 08/10/21 11:50 AM (2 years, 6 months ago)

https://github.com/jbloomlab/CoV_229E_antigenic_drift


Here is the modeling software for the antigenetic drift of sars-cov2


--------------------
[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


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InvisibleCrazy_Horse
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: koods]
    #27422530 - 08/10/21 11:52 AM (2 years, 6 months ago)

All of Indiana’s 92 counties deemed ‘high’ or ‘substantial’ risk for COVID transmission, according to CDC :cheer:


--------------------


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Invisiblechopstick
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: paradoxlost]
    #27422532 - 08/10/21 11:53 AM (2 years, 6 months ago)

Mass vaccinations correlated with spike in heart attacks in Israel

https://twitter.com/RanIsraeli/status/1425002893116166144


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InvisibleCrazy_Horse
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: chopstick]
    #27422535 - 08/10/21 11:55 AM (2 years, 6 months ago)

Glad I don't live in Isreal.


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InvisibleAsante
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: morrowasted] * 1
    #27422537 - 08/10/21 11:57 AM (2 years, 6 months ago)

Quote:

morrowasted said:
I mask up now in public despite being vaccinated


I don't know anyone vaccinated who has gotten so sick they had to be hospitalized but more and more vaccinated are definitely coming down with covid





:uhoh:


Thats a bad sign right there, coming from you.


--------------------
Omnicyclion.org
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Offlineparadoxlost
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Asante] * 1
    #27422553 - 08/10/21 12:09 PM (2 years, 6 months ago)

Quote:

Asante said:
Quote:

morrowasted said:
I mask up now in public despite being vaccinated


I don't know anyone vaccinated who has gotten so sick they had to be hospitalized but more and more vaccinated are definitely coming down with covid





:uhoh:


Thats a bad sign right there, coming from you.





Yea but he will never apologize for calling me cringy and saying I don't understand the processes that are occuring. I would say I 100% understand them, moreso then you, or koods, or boddhivista, or qman333 or anyone else who either called me retarded or insinuated as such.



People didn't get smarter all of a sudden when science became the new religion. All people are looking for an ideology that allows them to not have to think every waking second of their life so they can go around on autopilot. News flash. Life is supposed to be constant work. If it's not, you're going to wrong way


--------------------
[quote]koods said:
Asante, I don’t think we should have any sympathy and should celebrate the deaths of antivax/antimask activists. They are responsible for far more American deaths than al Qaeda ever was. Every time one of them dies ther movement of death is weakened.ut[/quote]

[quote]koods said:
Chasing variants with vaccines is a dumb idea[/quote]


Edited by paradoxlost (08/10/21 12:12 PM)


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Offlinekoods
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: paradoxlost]
    #27422558 - 08/10/21 12:13 PM (2 years, 6 months ago)

Quote:

paradoxlost said:
New question: which vaccine should I get and is it better or worse there are more then one vaccine going around


If you are a person who things in black and white, please don't answer.



Moderna or Pfizer for sure.

Wait six weeks between doses for maximum effect


--------------------
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