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koods
Ribbit



Registered: 05/26/11
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Asante] 1
#27309661 - 05/15/21 10:03 AM (2 years, 8 months ago) |
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You’re gonna feel like a dog turd tomorrow
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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Mr.GuessWork
Stranger

Registered: 03/30/13
Posts: 4,563
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: koods]
#27309672 - 05/15/21 10:14 AM (2 years, 8 months ago) |
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the peace of mind is worth it though. I got my second dose a while back, and it's nice to be able to look some maskless jerk in the eyes and know that his stupid ass won't be able to kill me just by breathing.
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koods
Ribbit



Registered: 05/26/11
Posts: 106,308
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Mr.GuessWork]
#27309678 - 05/15/21 10:18 AM (2 years, 8 months ago) |
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Yeah I’m done. Two weeks since the second moderna.
It just blows me away that on a site where people take drugs they ordered from China off the dark web, we’d have people complaining about the unknowns in a vaccine. I guess you can’t expect the highest level of common sense in a community of recreational drug users.
Edited by koods (05/15/21 10:21 AM)
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LeafRaker
nomad



Registered: 11/28/11
Posts: 718
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Mr.GuessWork]
#27309705 - 05/15/21 10:55 AM (2 years, 8 months ago) |
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Quote:
Mr.GuessWork said: the peace of mind is worth it though. I got my second dose a while back, and it's nice to be able to look some maskless jerk in the eyes and know that his stupid ass won't be able to kill me just by breathing.
You can feel a lot more secure he's not going to do you in, though he still might hurt you some.
Lots more work to do, unfortunately.
-------------------- Knowledge is finite, ignorance is infinite.
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Asante
Mage


Registered: 02/06/02
Posts: 86,958
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: koods]
#27309769 - 05/15/21 12:01 PM (2 years, 8 months ago) |
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Quote:
koods said: You’re gonna feel like a dog turd tomorrow
` Noted and fully prepared for with all sorts of creature comforts bought in advance. Even cranked up the thermostat and popped a valium. Aloha Asante 
If people wonder what a makeshift vaccination site from our GGD (infectious diseases org) looks like:

They commandeered the Event Hall of a center and turned it into a well organized mass vaccination site.
Our country has 17.5 million people and this week they are going to shoot a million vaccines.
Finally its getting on steam.
The vaccination experience was very pleasant because the medical people werent in bureacracy mode but in expedience mode. I arrived at the site 25 minutes too early, no consequence, they prcessed the minimum of information, the medical ones for safety, and omitted to even view half the documents I had to bring, the government ones which had no bearing on safety.
They welcomingly were all about getting it into you, you on the waiting chair and healthy out the door as fast as possible.
It was a very positive experience
One of the medics said: "as for adverse reports that AstraZeneca was a big mess, Moderna has far less adverse reports and we barely hear any about this Pfizer at all."
There was a 15 minute of sitting to check for problems but including that, I do believe I was out the door in 20 min flat.
Hat off to the GGD (our CDC) for the highly professional efficiency, I'm rather strict about the quality of medical care as I know a thing or two about it and saw some very big medical failures, including leading to my mother's death, and the GGD did everything right. Well set up, everyone "in the zone", they were chewing up the masses and could handle more capacity than they had at the time.
Quote:
koods said: It just blows me away that on a site where people take drugs they ordered from China off the dark web, we’d have people complaining about the unknowns in a vaccine.
Highly engineered vaccine with ingredients list available online: "theres no telling whats in it, can't risk it."
Bonnaroo: *sticks wet finger in baggie , sucks it and swallows "This is molly, right?"
-------------------- Omnicyclion.org higher knowledge starts here
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Asante
Mage


Registered: 02/06/02
Posts: 86,958
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Asante]
#27309827 - 05/15/21 12:43 PM (2 years, 8 months ago) |
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Pfizer is looking into a third dose of vaccine as a booster dose "it may increase antibodies a further 10-20x higher"
Moderna tests booster doses specific against the South African variant
I will be having 2 Pfizer after my 1 AstraZeneca so I'm looking into the effects of mixing vaccines and adding a third dose.
It seems promising, but using different vaccines is associated with greater incidence of side effects.
Logically however, greater incidence of sode effects triggers an even stronger immune response because immune response to a degree is incventivized by distress caused by the invader
-------------------- Omnicyclion.org higher knowledge starts here
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koods
Ribbit



Registered: 05/26/11
Posts: 106,308
Loc: Maryland/DC Burbs
Last seen: 2 hours, 55 minutes
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Asante]
#27309833 - 05/15/21 12:56 PM (2 years, 8 months ago) |
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All the vaccines use the exact same genetic code from the original Chinese RNA sequence to make the spike protein, so I’m not sure mixing vaccines has any value to increase the variety of antibodies. Unless they change the formula for the variants.
What’s amazing about the moderna and probably the Pfizer is they invented their vaccines without ever having the actual virus on hand. They just used the string of letters published in the Chinese paper.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
Edited by koods (05/15/21 12:59 PM)
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koods
Ribbit



Registered: 05/26/11
Posts: 106,308
Loc: Maryland/DC Burbs
Last seen: 2 hours, 55 minutes
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: koods] 1
#27309840 - 05/15/21 01:04 PM (2 years, 8 months ago) |
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Maryland dropped the mask mandate yesterday. Most stores it’s still mandatory but restaurants are packed and nobody is wearing masks except the staff. We have an extremely high vaccination rate around here. Middle and high schools are starting vaccination clinics for students 😎
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
Edited by koods (05/15/21 01:06 PM)
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koods
Ribbit



Registered: 05/26/11
Posts: 106,308
Loc: Maryland/DC Burbs
Last seen: 2 hours, 55 minutes
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: koods]
#27309862 - 05/15/21 01:30 PM (2 years, 8 months ago) |
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Meanwhile in India they had a stampede today to get remdesivir
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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Asante
Mage


Registered: 02/06/02
Posts: 86,958
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: koods]
#27309898 - 05/15/21 01:59 PM (2 years, 8 months ago) |
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Quote:
koods said: Maryland dropped the mask mandate yesterday. Most stores it’s still mandatory but restaurants are packed and nobody is wearing masks except the staff. We have an extremely high vaccination rate around here. Middle and high schools are starting vaccination clinics for students 😎
I hope it works out, I'm really happy for you guys!
The developing world will slide of straight into Hell though
It may be shocking how fast estimates will rise to 6 million, the Shoah, or 10 million, the Congolese holocaust. From there on up, WWI at 40M, WWII at 75M and the Spanish flu at 100M.
-------------------- Omnicyclion.org higher knowledge starts here
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LeafRaker
nomad



Registered: 11/28/11
Posts: 718
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: koods]
#27309961 - 05/15/21 03:18 PM (2 years, 8 months ago) |
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I've heard of credible entities looking into combinations of vaccines.
For one if the RNA is similar, brand loyalty might be unnecessary and that would make it easier to vaccinate people.
There's also some consideration of the possibility that mixing vaccines might improve response.
-------------------- Knowledge is finite, ignorance is infinite.
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LeafRaker
nomad



Registered: 11/28/11
Posts: 718
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Asante]
#27309965 - 05/15/21 03:22 PM (2 years, 8 months ago) |
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And the developing world's hell is very likely to have reverberations into our comfortable first-world bubbles. Interesting times, I'm afraid.
-------------------- Knowledge is finite, ignorance is infinite.
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Asante
Mage


Registered: 02/06/02
Posts: 86,958
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: LeafRaker] 2
#27310122 - 05/15/21 05:13 PM (2 years, 8 months ago) |
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Mixing Covid-19 vaccines tied to more side effects, early UK data suggests -- The researchers found that people who got different vaccines had more side effects following the second dose, with feverishness reported by 34% of those who received the AstraZeneca vaccine first and Pfizer vaccine second, compared with 10% of those given the AstraZeneca vaccine for both doses.
I maintain: stronger side effects = stronger immune response.
Right now my injection site is sore like it got knuckle-punched. There is a bit of feverishness, I'm sweaty mild so far.
I told the nurse "Stick it deep! I don't want to miss a microliter!" "Thats how I like it.." she said, fitting the syringe with a longer needle, "most are scared or complain." She jabbed it with skill. "As I see it you may just have saved my life, thank you!"
-------------------- Omnicyclion.org higher knowledge starts here
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koods
Ribbit



Registered: 05/26/11
Posts: 106,308
Loc: Maryland/DC Burbs
Last seen: 2 hours, 55 minutes
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: LeafRaker]
#27310153 - 05/15/21 05:44 PM (2 years, 8 months ago) |
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Quote:
LeafRaker said: I've heard of credible entities looking into combinations of vaccines.
For one if the RNA is similar, brand loyalty might be unnecessary and that would make it easier to vaccinate people.
There's also some consideration of the possibility that mixing vaccines might improve response.
The code that makes the spike protein is the same, but the adjuvants and method of makkkg the protein are different. Moderna and Pfizer are pretty damn close and only differ in the exact composition of the lipid coating.
The antibodies that would be produced with all the vaccines are the same.
One thing I didn’t realize about the way the antibodies are made that explains why variants are not killing the immunity is antibodies match up to only a random part of the protein - sometimes as few as six amino acids - not the entire thing so some antibodies don’t even use the parts of the protein where the mutations are located
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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koods
Ribbit



Registered: 05/26/11
Posts: 106,308
Loc: Maryland/DC Burbs
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Asante] 2
#27310157 - 05/15/21 05:47 PM (2 years, 8 months ago) |
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Quote:
Asante said: Mixing Covid-19 vaccines tied to more side effects, early UK data suggests -- The researchers found that people who got different vaccines had more side effects following the second dose, with feverishness reported by 34% of those who received the AstraZeneca vaccine first and Pfizer vaccine second, compared with 10% of those given the AstraZeneca vaccine for both doses.
I maintain: stronger side effects = stronger immune response.
Right now my injection site is sore like it got knuckle-punched. There is a bit of feverishness, I'm sweaty mild so far.
I told the nurse "Stick it deep! I don't want to miss a microliter!" "Thats how I like it.." she said, fitting the syringe with a longer needle, "most are scared or complain." She jabbed it with skill. "As I see it you may just have saved my life, thank you!" 
Probably because the Pfizer is a superior product
One problem with the AZ is that people can develop antibodies for the adenovirus vector, then with the second shot you body starts attacking that before it can do its magic
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
Edited by koods (05/15/21 05:49 PM)
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Asante
Mage


Registered: 02/06/02
Posts: 86,958
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: koods]
#27310647 - 05/16/21 02:40 AM (2 years, 8 months ago) |
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Quote:
One problem with the AZ is that people can develop antibodies for the adenovirus vector, then with the second shot you body starts attacking that before it can do its magic
Oooh nasty!
Quote:
Probably because the Pfizer is a superior product
It is. This morning, a little off, but less than last night. Main complaint is the painful injection site but I'm not complaining. Nowhere near the mess I got with AZ.
I believe that because I had such a massive adverse response to AZ, my immune system got mobilized to the utmost and that because of it, the follow up shot of Pfizer so far is benign.
This Pfizer feels like a "regular vaccine" in terms of sickness, not the extravaganza of AZ.
If you got any choice in the matter, get Pfizer.
-------------------- Omnicyclion.org higher knowledge starts here
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morrowasted
Worldwide Stepper


Registered: 10/30/09
Posts: 31,378
Loc: House of Mirrors
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Asante]
#27310747 - 05/16/21 06:17 AM (2 years, 8 months ago) |
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Dont speak too soon. The side effects may yet kick in. Takes up to 24hrs to really get going in some people. Usually more like 12 to 18.
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Asante
Mage


Registered: 02/06/02
Posts: 86,958
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: morrowasted]
#27310764 - 05/16/21 06:42 AM (2 years, 8 months ago) |
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OK, I'm willing to suffer them, within reason.
Its just about 23 hours after the shot now.
Lets see what develops.
-------------------- Omnicyclion.org higher knowledge starts here
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morrowasted
Worldwide Stepper


Registered: 10/30/09
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: Asante]
#27310772 - 05/16/21 06:50 AM (2 years, 8 months ago) |
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Oh yeah you may in the clear then. Glad you managed to get some security. You deserve it
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Asante
Mage


Registered: 02/06/02
Posts: 86,958
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Re: COVID-19 aka. SARS-CoV-2 - Main Thread on the Novel Coronavirus Pandemic PART 2 (Second Wave 2020-2021 season) [Re: morrowasted] 1
#27310776 - 05/16/21 06:52 AM (2 years, 8 months ago) |
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I'm a Shroomery Admin, I'm an essential worker
-------------------- Omnicyclion.org higher knowledge starts here
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