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Hi, so I've previously taken lower dose recreational trips and I'm looking to take a medicinal trip to help with my depression, anxiety, and PTSD. The dose of psilocybin I've seen in studies is 20mg/70kg and I'm a large dude... About 127kg, but I'm having a hard time gauging how many grams I would need. I know the best one could come to is an average amount psilocybin in mushrooms. Would I need more than a couple 1/8ths?
20mg/70kg is a very high dose for the average person. You'd want to take about 6 dried grams of p. cubensis to meet this dose. being larger will impact metabolism so this could be an ideal dose, but there are other factors that influence metabolism as well - 6 grams could be too high of a dose.
My best advice would be to go up in increments of +1 to +1.5 grams on top of what you've had experience with prior until you reach your ideal effects. This depends somewhat on what the doses of your "lower dose recreational trips" were - I'd caution against jumping from say 2 grams to 6 grams for example.
Keep in mind that the doses described in most studies use synthetic psilocybin that has been measured precisely whereas cubensis can vary to some degree so you likely won't hit the mark perfectly. On top of this, there are contextual differences when taking psilocybin medicinally at home versus in a therapy room with 2 trained psychotherapists. You can mimic the therapy setting for a similar experience, but if you dose too high in the therapy room, there are very strict safety precautions to respond appropriately; these can be hard to meet at home. I'd advise being somewhat more conservative about the dose for this reason.
In my opinion, 6 grams would be a high dose for a beginner. I am an average weight, experienced psychonaut and 6 gram trips can kick my ass. I like an eighth for a solid trip. 6 may be the perfect dose for you, however. If you have taken mushrooms before, what amount was considered a low dose for you at that time? Point being, don't jump from 1 gram to 6. Best wishes and safe travels man
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