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bob5

Registered: 03/01/09
Posts: 1,391
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I took 100mg harmala alkaloids 12hours ago. can i redose now?
#27141853 - 01/11/21 11:31 AM (3 years, 1 month ago) |
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I was planning a psilohuasca experience last night but i lay down while the rue was kicking in and fell asleep for 10hours. i think the maoi inhibition is defintley no longer active so i was considering redosing the harmala alkaloids (fullspectrum pure) now so that i can try psilohuasca again today.
whats the max amount of harmala alkaloids you can have in 24hours? also am i likely to get a double dose of harmala by redosing 12hours later? thanks
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kerelsk
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Re: I took 100mg harmala alkaloids 12hours ago. can i redose now? [Re: bob5]
#27141891 - 01/11/21 11:49 AM (3 years, 1 month ago) |
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You can dose them as frequently as you want, as far as I understand. Some say they have a slight degree of reverse tolerance over long periods of frequent use, others say it leads to a normal tolerance over time for them.
There's no reason this would be dangerous. Although if I dose for multiple days in a row it does feel like the harmalas build in your body so you might need a smaller dose.
Edit: I probably wouldn't exceed 500mg of harmalas in a 24 hour period, but at that point you'd probably be feeling pretty sick of harmalas anyway.
Edited by kerelsk (01/11/21 11:51 AM)
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Pandemoon
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Re: I took 100mg harmala alkaloids 12hours ago. can i redose now? [Re: kerelsk]
#27141913 - 01/11/21 12:02 PM (3 years, 1 month ago) |
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Sure you can redose now. Harmalas have a half-life of 3 to 4 hours in humans, so the initial dose is pretty much completly out of your system by now.
While 100mg is a low to medium dose to potentiate shrooms, 200mg taken at once is a standard dose to activate oral dmt.
So no need to worry, that's no high dose. 
Make sure to wait 30 to 40min between dosing the harmalas and the shrooms, for max. potentiation. Have fun and report back! 
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bob5

Registered: 03/01/09
Posts: 1,391
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Re: I took 100mg harmala alkaloids 12hours ago. can i redose now? [Re: Pandemoon]
#27141943 - 01/11/21 12:32 PM (3 years, 1 month ago) |
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heheh thanks. Shall do ! I'm getting quite fond of harmalas, interesting substance. ----------
200mg harmalas for DMT? ^^ Interesting. I had 100mg for my only oral DMT experience and the trip stopped after 1hour or something disappointing. It was going hard, and then suddenly vanished. I never got to the bottom of whether it was too low a dose of DMT or too low a dose of Harmalas.
I suspected it was too low a dose of harmalas at the time as it felt to my mind it was as if the enzymes came back online and booted the DMT out rather than the end of the trip. It was a savage drop off, similar to MDMA in it's abruptness.
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Pandemoon
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Re: I took 100mg harmala alkaloids 12hours ago. can i redose now? [Re: bob5]
#27142076 - 01/11/21 01:50 PM (3 years, 1 month ago) |
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I believe one could redose some more harmalas during an ayahuasca journey, to keep the magic going. (same with psilohuasca) 
But yes, 100mg is quite a low dose for oral dmt. I'd eat at least 150mg initially, then take 50mg more along with the dmt.
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bob5

Registered: 03/01/09
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Re: I took 100mg harmala alkaloids 12hours ago. can i redose now? [Re: Pandemoon] 2
#27143086 - 01/12/21 02:25 AM (3 years, 1 month ago) |
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well psilohuasca is a powerful medicine. i had 100mg rue alkaloids and only 1.5g cubensis. Wanting to play it safe as my last psilohuasca with 4acodmt left me in quite a dark place.
it was a difficult trip.. but im so glad i did it. there were points everything was too much and i got depressed... rue seems to have a depressant effect on me but it helps me learn from the experience of being depressed. combined with the healing nature of psylocybin its a wonderful combination.
i capusulated the rue alkaloids as yuck drinking that stuff i almost puked while drinking it last time and said to myself never again. i noticed the 'heavy stomach and gear-shift' at T+ 47 minutes from the harmalas but i waited another 10minutes before drinking the shroom tea. I figured with my pretty empty stomach the rue capsule would add 10minutes onto the onset duration versis rue tea. semmed to be about right. At T+56minutes i started feeling drunken from the rue and i backed the cold shroom tea.
im still high.. not tripping but more than an afterglow and its been over 12 hours. i think i had a 3 hour nap at some point. not much for a nights sleep but i did dose at 8pm. the peak wasnt much longer than usual interestingly. maybe 50% longer but the high has been at least double the length. youve got me curious what effect redosing rue would have mid trip. feeling very rested and peaceful this morning. i have some shit to get done.. i made a list of things i will do today, it helped me through the peak of the trip which was quite challenging. But im tempted to have some more rue afterwards. maybe up the dosage to 150mg to get a feel for what thats like with no tryptamines involved.i in preparation for ayahusca take 2 whenever that may be. B
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Pandemoon
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Re: I took 100mg harmala alkaloids 12hours ago. can i redose now? [Re: bob5]
#27143125 - 01/12/21 03:26 AM (3 years, 1 month ago) |
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Thanks for reporting backl! Glad you feel peaceful now afterwards.  Shrooms can be challenging sometimes. What was it that made the peak difficult? Too strong effects? Too much negative thoughts? Too much of a body high? It would be interesting to know.
Was the trip somehow different to a trip without harmalas? Some people say the nature of the trips change comepletly due to harmalas. I find it adds more layers the the experience. Do you concur?
My first psilohuasca journey was with 120mg of harmalas and 2.2g of cubes lemon teked. Was not difficult at all, instead I was in awe how strong and long the trip tunred out to be.
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Picaflor
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Re: I took 100mg harmala alkaloids 12hours ago. can i redose now? [Re: Pandemoon]
#27144069 - 01/12/21 03:08 PM (3 years, 1 month ago) |
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Harmine has a half-life of 20 minutes. Harmaline -- around 1.5-2 hours.
500 mg harmaline within 24 hours is not much.
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LeafRaker
nomad



Registered: 11/28/11
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Re: I took 100mg harmala alkaloids 12hours ago. can i redose now? [Re: Picaflor]
#27145142 - 01/13/21 06:23 AM (3 years, 1 month ago) |
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The difference in half-life has me wondering about so much. I thought caapi was almost entirely harmine, Syrian rue I thought was something like 2/3 harmaline. I'm guessing this explains different protocols with aya- and psilo-huasca.
Also, what's your surmise on the upper limits (and their mechanisms) for harmalas? I use more harmalas than is typically recommended for psilohuasca and have not had a serious issue, but would always like to know for harm-reduction and other improvements to the experience.
-------------------- Knowledge is finite, ignorance is infinite.
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