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OfflinePsilocybe Catalyst
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Need help identifying what nullifies my psilocybin experience!
    #27120733 - 01/01/21 04:35 PM (3 years, 27 days ago)

I currently take two medicines.

#1 - Gabapentin - I take this for nerve pain, and back problems. I take 1800mg a day, everyday. I had taken this medicine at a lower dose, during previous mushroom trips with no noticeable differences in my trip. Not sure if this could be causing the mushrooms to be nullified or not.

#2 - Kratom - This I also take for pain, several times a day. It's a herbal supplement that works good with my back pain and gives me some energy. I take anywhere from 6-7 grams a dose. I dose it 3-4 times a day, everyday.

I like to take mushrooms for my depression. I find that if I take them about every month or so, my depression doesn't flare up too badly, and is much easier to deal with. However, the last 4-5 trips, I haven't gotten much out of them. I take 3.5-4 grams each time. I feel the come up on them, like I normally do. After the come up though, it just does nothing. I feel spaced out like normal, but no euphoria, and no introspection at all. No visuals usually either.

I'm DESPERATE to find out what is going on. I rely on mushrooms for my depression, and have no other solution. Please, if you even THINK that you might know what's going on, help me. I have tried skipping my gabapentin dose for the day, until after I trip. Doesn't work. I've also tried skipping Kratom until afterwards. Doesn't work either. Any and all advice will be greatly appreciated. Thanks.


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OfflineDr. Delban
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Psilocybe Catalyst]
    #27120744 - 01/01/21 04:45 PM (3 years, 27 days ago)

How often do you take mush? Maybe you've build up tolerance?


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OfflinePsilocybe Catalyst
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Dr. Delban]
    #27120749 - 01/01/21 04:47 PM (3 years, 27 days ago)

Sorry, should have clarified that in my post...

I take mushrooms about once every 5 or 6 weeks usually. The last trip, was last week. That was the first time I tripped in about 3 or 4 months, because I ran out. I don't do any other drugs besides a little weed once and a while. At least outside of the prescription gabapentin, and kratom supplement for pain.


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Offlinetacodude
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Psilocybe Catalyst] * 1
    #27120753 - 01/01/21 04:50 PM (3 years, 27 days ago)

Most likely the gabapentin because it works in the same receptor area as benzos even though it does not hit the same specific receptors


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InvisibleLeafRaker
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Psilocybe Catalyst] * 1
    #27120775 - 01/01/21 05:04 PM (3 years, 27 days ago)

Am I right you were working with a new source of mush last time? It bears repeating that there' much variation in mush and that might be at issue here.


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OfflinePsilocybe Catalyst
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Re: Need help identifying what nullifies my psilocybin experience! [Re: LeafRaker]
    #27120961 - 01/01/21 06:55 PM (3 years, 27 days ago)

So, it's been a problem for the last 4 or 5 times i've taken mushies. I took Golden Teachers this last time, but the times before that, let's say 3 times before that, I was taking Burma. Burma that was fresh, much like these golden teachers. They worked at first, but I feel like slowly stopped working as well for me over a couple of months. I think maybe Gabapentin is my best guess at why they don't work as well.

Does anyone know how long i'd have to stop taking gabapentin to get the magic back?


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OfflinePsilocybe Catalyst
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Re: Need help identifying what nullifies my psilocybin experience! [Re: tacodude]
    #27120967 - 01/01/21 07:00 PM (3 years, 27 days ago)

So, let's assume it is in fact the gabapentin. What are my options? Can I increase my dose of mushies to overpower the gabapentin? It has a very small half life, so I could potentially have it out of my system entirely within 2 days of not taking it at all. I'd rather just take a larger dose though, if possible.


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InvisibleLeafRaker
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Psilocybe Catalyst]
    #27120981 - 01/01/21 07:10 PM (3 years, 27 days ago)

Hmm. I've never had gabapentin, but I know some folks who have and it does seemed to pervade a lot of things, but is highly variable. In particular dose and timing might help.

Also, if you have a fairly consistent source, I'd wonder about trying to titrate your doses upwards. I'd start with maybe 25-30% more than I've done before and then possibly adding about 25% more each time. Some of us (like me!) just seem to need more so it might not be a gabapentin issue.


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Knowledge is finite, ignorance is infinite.


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OfflineRise against
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Re: Need help identifying what nullifies my psilocybin experience! [Re: LeafRaker]
    #27121085 - 01/01/21 08:20 PM (3 years, 27 days ago)

Interesting, I also take 1800mg of gabapentin. I haven't really noticed it affecting my trips but everybody is different I guess. What dose of mushrooms do you take? I typically dose pretty high when I do trip.


Edited by Rise against (01/01/21 08:21 PM)


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InvisibleLeafRaker
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Rise against]
    #27121099 - 01/01/21 08:28 PM (3 years, 27 days ago)

For true journeys, I like 5g+ of things like Ovoids or more like 3g+ of things like psilocybe cyans, those species are probably 10% to 60% stronger than cubes. I like microdosing and museum/concert doses equivalent to 1g cubes or so, but the middle area between that and serious journeys has an uncomfortable 'neither fish nor fowl' feeling for me.


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Knowledge is finite, ignorance is infinite.


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OfflinePsilocybe Catalyst
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Rise against]
    #27121399 - 01/02/21 12:41 AM (3 years, 26 days ago)

Right now I have Golden Teachers. Typically I take no less than 3.5 grams. Lately, like I said, i've gotten nothing but the come up. So when I take them next time, i'm going to try 4.5 grams. I love taking higher doses anyways, so I'll give it a shot and see what happens. I'll report back and let you guys know how it goes. Probably tomorrow or Sunday. Either way, thanks for the advice. Hopefully this post can help someone else in the future if nothing else.


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OfflinePandemoon
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Psilocybe Catalyst]
    #27121574 - 01/02/21 06:15 AM (3 years, 26 days ago)

I heard regular kratom use can diminish psychedelic effects, too.

-


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OfflinePrimalSoup
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Psilocybe Catalyst]
    #27122848 - 01/02/21 08:59 PM (3 years, 26 days ago)

Quote:

Psilocybe Catalyst said:
So, it's been a problem for the last 4 or 5 times i've taken mushies. I took Golden Teachers this last time, but the times before that, let's say 3 times before that, I was taking Burma. Burma that was fresh, much like these golden teachers. They worked at first, but I feel like slowly stopped working as well for me over a couple of months. I think maybe Gabapentin is my best guess at why they don't work as well.

Does anyone know how long i'd have to stop taking gabapentin to get the magic back?





Where are you getting them?  Are you growing them?  Either way the actual potency can vary independent of the strain - and with mushrooms if you don't have enough you get the comeup effects but not much of the trip effects.

A quick search doesn't show any sort of disaffect for Gabapentin and classical psychedelics. :cookiemonster:


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OfflinePsilocybe Catalyst
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Re: Need help identifying what nullifies my psilocybin experience! [Re: PrimalSoup]
    #27129386 - 01/05/21 10:04 PM (3 years, 23 days ago)

I grow them. When I took them, they were dried and stored the day before I took them. They are Golden Teachers this time. I took 3.5 grams, which is usually enough. I don't know. Might try to trip again this weekend, just not sure what to change before I do.


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OfflinePrimalSoup
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Psilocybe Catalyst]
    #27129413 - 01/05/21 10:31 PM (3 years, 22 days ago)

OK.  So are they multi spore or isolates?  Might try taking them fresh first though in case the drying has some effect, as its possible to screw that up too.  Or make tea for best results and still being able to blend fruits for potency.


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OnlineschmutzenS
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Re: Need help identifying what nullifies my psilocybin experience! [Re: PrimalSoup]
    #27130179 - 01/06/21 11:36 AM (3 years, 22 days ago)

Eat an orange immediately after eating the mushrooms.


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OfflineDr. Delban
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Re: Need help identifying what nullifies my psilocybin experience! [Re: schmutzen]
    #27130252 - 01/06/21 12:14 PM (3 years, 22 days ago)

Quote:

namaste said:
Eat an orange immediately after eating the mushrooms.




Eat a bowl of blackcurrants.

OR

3 heaped tablespoons of RAW cacao powder


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Invisibleopenmind
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Re: Need help identifying what nullifies my psilocybin experience! [Re: Pandemoon]
    #27130513 - 01/06/21 01:37 PM (3 years, 22 days ago)

Quote:

LeafRaker said:
Am I right you were working with a new source of mush last time? It bears repeating that there' much variation in mush and that might be at issue here.





That's what I'm thinking....

If the OP is working with a different "batch" or source of mushrooms than they have been, then perhaps the newest mushrooms they're working with just aren't as potent as the others :shrug: .





Quote:

Rise against said:
Interesting, I also take 1800mg of gabapentin. I haven't really noticed it affecting my trips but everybody is different I guess.





I'm not too familiar with the drug or its mechanism of action, but I haven't heard anything about it dulling down psychedelics from others that take it.





Quote:

Pandemoon said:
I heard regular kratom use can diminish psychedelic effects, too.

-





I've been taking kratom daily for 8+ years now and have had it in my system pretty much every time I've tripped since then, I haven't noticed it dulling down my trips at all.

I have seen a few folks online claim it prevents them from tripping or dulls down the trip, but that's not how it goes for myself or anyone else I know that takes kratom.






-OM

.


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OfflineTyperwritermonky
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Re: Need help identifying what nullifies my psilocybin experience! [Re: openmind]
    #27136684 - 01/09/21 12:47 AM (3 years, 19 days ago)

Gabapentin can definitely slightly dull a psychedelic experience, but moreso of that how alcohol would effect the experience.  It works on regulating calcium ion channels and doesn't exert GABA action directly.. just skip your gabapentin dosage, and at the end of the trip take your dosage.  You can take 1/4 the dosage to ensure no anxiety or body issues from not having the medication.


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