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TH-E
Grandma



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Long term, daily consumption of psilocybin mushrooms
#27085980 - 12/12/20 03:27 PM (3 years, 1 month ago) |
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Im sure similar questions have been asked before but I'm having trouble finding what I'm looking for on the forum or online and I would like to hear some fresh takes and discussion! A lot of the information I did find were studies on the long term benefits of singular or infrequent psilocybin experiences or on weekly micro dosing but...
Whats happens if you take psilocybin mushrooms every day for, let's say, a year?
Are there any long term studies on the effects of regular(daily) high dosing of psilocybin?
Does psilocybin or any of the other active chemicals in psychedelic mushrooms affect your body in other ways (like metabolically) even after you build a tolerance?
Is there a certain amount of psilocybin that your body can't produce a gradual tolerance to? And If you have a tolerance and don't get the psychoactive effects but are taking psilocybin at high doses how does it affect you, are there any studies on this?
Are there any people or cultures out there that eat some sort psychedelic plant or fungi as a staple in their diet and therefore immune to the psychoactive effects but receive nutritional or other benefits from it?
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LeafRaker
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Re: Long term, daily consumption of psilocybin mushrooms [Re: TH-E]
#27086190 - 12/12/20 05:58 PM (3 years, 1 month ago) |
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I'm almost positive there are not studies on this. Most questions in any area are unstudied. And these substances are not the subject of large amounts of study, anyway.
Some individuals have tried such things, though. A frequent, but not necessarily universal, response is that there's a diminution in positive effects, but an accumulation in negative ones. Just remember this isn't likely a new idea and even those who evangelize for psilocybin mushrooms recommend breaks.
-------------------- Knowledge is finite, ignorance is infinite.
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PrimalSoup
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Re: Long term, daily consumption of psilocybin mushrooms [Re: TH-E] 1
#27086431 - 12/12/20 08:59 PM (3 years, 1 month ago) |
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Quote:
TH-E said: Im sure similar questions have been asked before but I'm having trouble finding what I'm looking for on the forum or online and I would like to hear some fresh takes and discussion! A lot of the information I did find were studies on the long term benefits of singular or infrequent psilocybin experiences or on weekly micro dosing but...
Whats happens if you take psilocybin mushrooms every day for, let's say, a year?
Are there any long term studies on the effects of regular(daily) high dosing of psilocybin?
Does psilocybin or any of the other active chemicals in psychedelic mushrooms affect your body in other ways (like metabolically) even after you build a tolerance?
Is there a certain amount of psilocybin that your body can't produce a gradual tolerance to? And If you have a tolerance and don't get the psychoactive effects but are taking psilocybin at high doses how does it affect you, are there any studies on this?
Are there any people or cultures out there that eat some sort psychedelic plant or fungi as a staple in their diet and therefore immune to the psychoactive effects but receive nutritional or other benefits from it?
I've dosed semidaily (3-5 days a week) several times for up to a few months at a time. This was with tea from fresh, and dosages adjusted to compensate for tolerance, so that the day's trip would start with strong visuals and proceed normally after that. This takes about a 50% increase each successive day, up to about 5 x baseline dosage (i.e., tops out at 250 g fresh), at which point tolerance stops increasing. So it basically takes a shitload of mushrooms to do this.
But it works, with no downside, other that blunted affect when going off them, which is pretty much expected - lasts for a few days at most.
This isn't a study, just what I've done in pursuit of other goals (research and writing).
You have to have the time, place, and space to do this right, if you want to do it.
There are no studies SFAIK, why would there be? 
You may be asking about daily dosing of like a few grams (dried) though, with no increase for tolerance. There are at least a few people here who've done that to. I'm thinking about it as well as an alternative to microdosing, with possible greater benefits...
TL;DR No downside other than growing a lot of shrooms. YMMV of course.
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Rise against
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Re: Long term, daily consumption of psilocybin mushrooms [Re: PrimalSoup]
#27086438 - 12/12/20 09:09 PM (3 years, 1 month ago) |
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Tolerance stops at 250g of fresh mushrooms? That is a lot of mushrooms
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4HO-DMT


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Re: Long term, daily consumption of psilocybin mushrooms [Re: PrimalSoup]
#27086458 - 12/12/20 09:42 PM (3 years, 1 month ago) |
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Quote:
PrimalSoup said: ... This takes about a 50% increase each successive day, up to about 5 x baseline dosage (i.e., tops out at 250 g fresh), at which point tolerance stops increasing. So it basically takes a shitload of mushrooms to do this...

Solid
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PrimalSoup
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Re: Long term, daily consumption of psilocybin mushrooms [Re: Rise against]
#27086465 - 12/12/20 09:58 PM (3 years, 1 month ago) |
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Quote:
Rise against said: Tolerance stops at 250g of fresh mushrooms? That is a lot of mushrooms 
That is indeed. It's why I grow PE strains primarily, gets it down to about 150 g fresh.
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Rise against
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Re: Long term, daily consumption of psilocybin mushrooms [Re: PrimalSoup]
#27086479 - 12/12/20 10:27 PM (3 years, 1 month ago) |
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Quote:
PrimalSoup said:
Quote:
Rise against said: Tolerance stops at 250g of fresh mushrooms? That is a lot of mushrooms 
That is indeed. It's why I grow PE strains primarily, gets it down to about 150 g fresh. 
What motivates you to dose this way? Do you just like to trip or do you find benefits to taking these doses often?
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PrimalSoup
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Re: Long term, daily consumption of psilocybin mushrooms [Re: Rise against]
#27087216 - 12/13/20 12:38 PM (3 years, 1 month ago) |
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It's what it takes to do the stuff I've been doing with it. Writing, it vastly enhances creativity - I can narrate stories/books and actually see (in minds eye and visuals) what is happening in the story, like an excellent movie that I'm just describing. This is done in the dark BTW while recording it for later transcription.
The research project is another sort of thing, investigating timeline transfer of information (music mostly) and working on how to capture what is heard without suppressing the trip effects. It also points towards some fascinating fundamental physics that is incredibly hard to wrap one's mind around me, but looks promising. I've written some of it up in threads and journal posts (which also link threads).
If the stars align I can get into this stuff (daily megadosing) maybe once a year, but have averaged less than that due just to the demands of doing it. 
And I don't really trip much any other way anymore, which is mostly why I'm interested now in daily doses around a gram or two, to find out what that does as well. There was another thread on daily dosing a while back (which I can't find), and what you'd expect (as opposed to microdosing where there's no obvious effect) consuming a marginally effective dose daily is quickly modified by tolerance. But if the effects of microdosing scale with the dosage then regular daily dosing should show more results. Don't really know, have tried it yet.
I got into back-to-back trips long ago when I found it much more useful for personal progress and stuff like that then sporadic one-offs. Other people have found similar benefits.
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TH-E
Grandma



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Re: Long term, daily consumption of psilocybin mushrooms [Re: PrimalSoup]
#27088281 - 12/14/20 05:44 AM (3 years, 1 month ago) |
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This is really cool! Thanks for sharing your experience experimenting with this. I'm really just curious rather than thinking about doing such myself but I have experimented with something in-between micro dosing and mildly dosing in an attempt to bolster my creative juices, specifically for writing. I am horribly unproductive and unfocused WHILE feeling the mushroom effects but super focused and creative AFTER the effects dissipate and I'm left with that sort of euphoric mushroom "hangover". The only thing I found that helps focus my attention when I first start tripping is to exercise and get the blood really pumping. I guess part of my thinking is that maybe I could tap into that euphoric after effect without the full on trip if I have a tolerance and took higher doses but it sounds like that would be no different than a low dose with a tolerance.
Have you ever taken Kratom? Kratom has multiple active alkaloids and if you take it in low doses one effects you much like caffeine but if you take enough another active sort of outweighs the effect of that caffeine-like alkaloid and you feel more of an opiate sensation. I was wondering if there might be anything similar happening with mushrooms when taking high enough doses with a tolerance
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PrimalSoup
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Re: Long term, daily consumption of psilocybin mushrooms [Re: TH-E]
#27089003 - 12/14/20 02:58 PM (3 years, 1 month ago) |
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I don't get different sensations from mushrooms with a tolerance, honestly. The trip remains the same... 
The cool thing about writing with mushrooms (and I started doing that years before I actually did the daily dosing part of it) is the way it gets you all the way to prolific. I'd struggled a lot with that, and being slow means it takes a lot longer to get to the same sort of result. Narrating while tripping daily (about an hour or so) just gets the stuff pouring out, and all the difficulties of ordinary approaches (at a keyboard) disappear. That and the focus.
I will say it took some practice though. I used to do the writing in the afterglow primarily, and the focus is good there too, but nothing compared to what happens in the full trip (about an hour in generally). I would wait for the visuals to subside and the album I had on for the comeup to end and then it was straight to work - day after day, week after week. Got through many short stories (the warmup) and over a dozen books in a science fiction series that way.
And this was over a couple of years, although the work of editing and finishing remains. Previous novels (to get to finished) occupied more like 5 years at best, which is not really a commercial speed.
I think what the mushrooms do is blow out all the inhibitions and blocks, letting you just focus on the work itself.
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if you stand too close to the machine it'll start to eat youPrimal's simple tested teks and projects: Wheat Prep 2.0 Acidic Tea Tek Potency Project!
Edited by PrimalSoup (12/14/20 03:26 PM)
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