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Offlinequillip
Spiritual Void
Registered: 10/20/20
Posts: 35
Last seen: 2 years, 7 months
4-HO-MET, DPT and MAOIs?
    #27071761 - 12/04/20 12:27 PM (3 years, 2 months ago)

Hello, this is more of a curiosity question at this point, but I was just wondering if these two RCs (in salt form) require a MAOI to be orally active? There doesn't seem to be anything online suggesting they do, but I figured it could be because the average person taking RCs doesn't feel the need to point that out...


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smash that default network yo (but do it carefully)


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Offlinejesusfish
Naive Tripper
Male

Registered: 09/17/20
Posts: 72
Loc: Wisconsin Flag
Last seen: 2 years, 6 months
Re: 4-HO-MET, DPT and MAOIs? [Re: quillip]
    #27071919 - 12/04/20 01:35 PM (3 years, 2 months ago)

4-HO-MET shouldn't need one because the 4-hydroxy group should protect the molecule from the monoamine oxidase enzymes that break down DMT.

According to erowid DPT is "weakly" orally active, so I would assume it needs an MAOI to be fully active


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LOVE


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OfflineSleepyE
DMT is metaphysical
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Registered: 07/21/08
Posts: 8,760
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Re: 4-HO-MET, DPT and MAOIs? [Re: jesusfish]
    #27080940 - 12/09/20 06:16 PM (3 years, 2 months ago)

i tried oral dpt without maoi and it didnt work


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My Drawingzz
Draw DMT!

Trip Report: SHROOMS DMT---- My Youtube Psychedelic Channel


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OfflineNature Boy
Stranger than most
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Registered: 07/09/07
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Re: 4-HO-MET, DPT and MAOIs? [Re: SleepyE]
    #27081024 - 12/09/20 07:02 PM (3 years, 2 months ago)

I have experience with DPT.  In fact, I have most all of an entire gram sitting in a safe for probably 3 years, virtually untouched.
I refer to it as DMT's poorer cousin.  You can insufflate it, or vaporize.  it's nasty either way...much longer acting than DMT.  I'd have to refer to my encrypted notes to say much more (different computer)as I haven't been inclined to use it for a long time.  IIRC, it is a bit stimulating, and gave me a lot of muscle fasiculations at the modest dose that I felt I did not want to exceed.

If you search this site you will undoubtedly find my reports on the substance if you wish to learn more.


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All submitted posts under this user name are works of pure fiction or outright lies.  Any information, statement, or assertion contained therein should be considered pure unadulterated bullshit.  Note well:  Sorry, but I do not answer PM's unless you are a long-time trusted friend.  If you have a question, ask it in the appropriate thread.

                                                                               


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OfflineSleepyE
DMT is metaphysical
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Registered: 07/21/08
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Re: 4-HO-MET, DPT and MAOIs? [Re: Nature Boy]
    #27081057 - 12/09/20 07:19 PM (3 years, 2 months ago)

my hcl was a bit reddish/powdery, my buddy gave me a large bag full of different RC's both tryptamine and phenylethylamine since i he was finally able to try actual dmt, so i dont know the quality or age of the product.

i tried insulfflate it mostly, it seemed unpleasant to smoke, and its bad up the nose but i got used to it with a grapefruit chase

i was expecting OBE's possibly but never achieved that, though im not sure how pure it was, i remember i was insufflating 60mg+ a dose maybe more it was so long ago.
though it had some really great tribal patterning on the walls, very fun to watch


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My Drawingzz
Draw DMT!

Trip Report: SHROOMS DMT---- My Youtube Psychedelic Channel


Edited by SleepyE (12/10/20 11:18 AM)


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OfflineNature Boy
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Registered: 07/09/07
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Re: 4-HO-MET, DPT and MAOIs? [Re: SleepyE] * 1
    #27081602 - 12/10/20 05:29 AM (3 years, 2 months ago)

Yikes!  You can't vaporize DPT hcl! - or at least you shouldn't try!  You need to convert it to freebase (like DMT) first.  See this post and trip report:

https://www.shroomery.org/forums/showflat.php/Number/25177134#25177134


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All submitted posts under this user name are works of pure fiction or outright lies.  Any information, statement, or assertion contained therein should be considered pure unadulterated bullshit.  Note well:  Sorry, but I do not answer PM's unless you are a long-time trusted friend.  If you have a question, ask it in the appropriate thread.

                                                                               


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OfflineSleepyE
DMT is metaphysical
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Registered: 07/21/08
Posts: 8,760
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Re: 4-HO-MET, DPT and MAOIs? [Re: Nature Boy]
    #27081971 - 12/10/20 11:13 AM (3 years, 2 months ago)

yeah i didnt try smoking the hcl, just insufflation. nice il check it out! i have a Canadian vendor that i get my 4-aco-dmt and 1p-lsd from and i believe they have dpt in stock as well, was planning on trying it again soon. would be interesting to compare to the other batch i tried



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My Drawingzz
Draw DMT!

Trip Report: SHROOMS DMT---- My Youtube Psychedelic Channel


Edited by SleepyE (12/10/20 11:15 AM)


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OfflinePandemoon
Ἧeẍeᾐmeḭsṫeŗ ͛
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Registered: 01/28/14
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Re: 4-HO-MET, DPT and MAOIs? [Re: SleepyE]
    #27083618 - 12/11/20 08:48 AM (3 years, 2 months ago)

4-HO-MET doesn't require any MAOI, it's totally active on it's own. Be carefull, it's pretty potent in doses around 20 to 30 mg already. :thumbup:

I have no experience with DPT. :shrug:

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OfflineSleepyE
DMT is metaphysical
Male User Gallery


Registered: 07/21/08
Posts: 8,760
Loc: Ontario, Canada, Flag
Last seen: 3 days, 18 hours
Re: 4-HO-MET, DPT and MAOIs? [Re: Pandemoon]
    #27083622 - 12/11/20 08:52 AM (3 years, 2 months ago)

oddly enough i remember when i had 4-ho-met and i tried potentiating with maoi and didnt seem to have an effect


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My Drawingzz
Draw DMT!

Trip Report: SHROOMS DMT---- My Youtube Psychedelic Channel


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