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Offlineblueberrybenzos
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Psilocybe Cyanescens Surprisingly Potent?
    #27069429 - 12/03/20 07:37 AM (3 years, 1 month ago)

So to start this off, i’m an 18 year old living in Washington, i’ve been tripping for 2 years but i made a decision to stop buying from people due to bad trips. I said that i would only trip if the mushrooms found me. long story short i’ve had 2 unsuccessful years of hunting. until now that is. my sister invited me to a park that i’ve checked for shrooms before and decided i would have no luck. i went to walk the dogs with her and i stumbled across a fat patch of Psilocybe Cyanescens. I identified the little bugger and ate one as a taste test while i dry the others. 45 minutes later i start seeing the walls shift around and i became very confused? I ate one singular Cyanescen!!

anyways, before i knew it i was tripping my balls off, i’m guessing it was because it was fresh but this actually felt stronger than my 5 gram trip from a mix of Cubensis and Azurescens. this trip was about 2 days ago and i’m still so confused. it was an amazing trip that ended with an ego death but i just came on here to see if anyone knows why i got such a strong effect.

My guess is that my prior trips had altered my brain chemistry. the reason i think this is because i did some unknown acid which i’m pretty sure was 25i-Nbome (some shitty dealer told me it was real) and it was a complete horror trip. ever since that trip i haven’t been able to enjoy weed the same way that i used to and i began having strange fears, paranoia and anxiety. i mean i’m not complaining that i need less to trip now and it seems like this cyan trip healed me from all the things that 25i cursed me with. anyways i was just extremely curious. so that’s my story. mush love ☮️


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Offlineholofractal
Woodlover experimentalist
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Registered: 10/14/18
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: blueberrybenzos] * 2
    #27069466 - 12/03/20 07:52 AM (3 years, 1 month ago)

Fresh wood lovers are extremely potent, they should be treated with care. Usually 1.5/2g of dried cyans is enough, almost too much for me. Although I am getting older and these days have less reasons to indulge, once in awhile the shrooms are calling my name. There's a place and time for everything.

I hear what you mean with weed. One trip changed it all for me. I really would like to know what's up with that. I tripped on shrooms, it went south after smoking and to this day, 6 years later, no substance will give me anxiety quite like weed. Just irrational stuff that I know to be false, thinking of things about myself that are exaggerated. You know, some of it may be true, but to the extent that weed makes me "feel" these things is a bit much.

25i is a nasty drug. Be careful what you buy, if it's bitter it's a spitter.


--------------------
Woodlover lover!
I am open to questions about wood lovers, I don't know everything, but if you like my posts and have a question, feel free to ask in a PM
I do a lot of indoor experiments. I, one day, WILL figure out a surefire method for indoor woodlovers. Nothing is impossible.

Indoor Woodlover experimentation Journal
Indoor woodlover information - condensed
Indoor azurescens :laugh:


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OfflineImmortalZodd
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: holofractal]
    #27069627 - 12/03/20 09:13 AM (3 years, 1 month ago)

I have had a similar experience after dosing an research chem of some kind and then smoking weed a few days afterwards.


After smoking I immediately went into a downward spiral and proceeded to have a bad mental trip, in which I needed the support of a friend of mine to drive me home so that I could ride it out in bed. I had never had an experience like that before from smoking bud and I have never had it since, thus leading me to believe that there was some kind of neurological interaction going on with my recently dosed brain.


I can't personally affirm the potency of the cyan you ingested but I can confirm that there can be a different interactions when RCs are involved, at least according to my own experiences.


--------------------
...the illegality of cannabis is outrageous, an impediment to full utilization of a drug which helps produce the serenity and insight, sensitivity and fellowship so desperately needed in this increasingly mad and dangerous world.

Carl Sagan


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OfflinePandemoon
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: ImmortalZodd]
    #27069751 - 12/03/20 10:40 AM (3 years, 1 month ago)

Did the blotter numb your tongue & mouth for 10 minutes, or tasted like a strong peppermint? If yes then it was most likely some kind of 25x-nBOME.
If it was tasteless it was probably just LSD.

LSD + cannabis causes extreme anxiety & paranoia. I don't smoke weed anymore on any kind of psychedelic due to that reason. At least not before or during the peak.

-


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OfflineEclipse3130
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Pandemoon]
    #27070115 - 12/03/20 01:49 PM (3 years, 1 month ago)

Depending how big the one you ate was, I think you were more so just surprised of the potency. They are generally around twice the strength as most cubensis. Fresh ones 3x.

Fresh is always super potent, dried 1.5 - 2.5g is usually equivalent to 3.5 - 7g cubes if they really are extremely potent


--------------------
"In The Material World One seeks retirement and grows Old
In The Magical World One seeks Enlightenment and grows Wiser
In The Miraculous World One seeks nothing and grows Lighter
As we all tread the Homeward Path we will explore many Realms
And one day... we will all Realize that all experiences are Simply
Different ways in which The
All-That Is
Perceives Itself"


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Invisibleopenmind
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: holofractal]
    #27071800 - 12/04/20 12:45 PM (3 years, 1 month ago)

Quote:

holofractal said:
Fresh wood lovers are extremely potent, they should be treated with care.





:yesnod:





Quote:

Eclipse3130 said:
Depending how big the one you ate was, I think you were more so just surprised of the potency. They are generally around twice the strength as most cubensis. Fresh ones 3x.

Fresh is always super potent, dried 1.5 - 2.5g is usually equivalent to 3.5 - 7g cubes if they really are extremely potent





Yea, I concur with that.

IME over the years I def find most woodlovers like cyans and allenii to be 2x to 3x the potency of any cubensis I've ate. A single dry gram of allenii I find to consistently be nearly as potent as a full 8th of cubensis, 1.2g to 1.5g of allenii usually puts me around the same place an 8th of cubes does.

And when fresh they are even more ridiculously potent....Somewhat similar to the OP's story, there's been a couple times that I've ate just one single medium sized fresh mushroom (that would weigh around 0.7g to 0.9g if dry) within a few hours after picking it, and it had me far beyond anywhere that an 8th of cubensis has taken me.

I'm very aware of how potent woodlovers can be, I've worked with mostly woodlover species over the past 7 years or so...but when eating them fresh I have certainly been caught off guard and surprised at how "far out" and ridiculous high I've been from eating just one single medium sized mushroom.



I love em' when they're fresh though!...There's is such a "zing" to fresh woodlovers other than just being more potent. I feel there's a lot more going on and more layers & depth & richness to the experience when I eat them fresh. Since they only fruit during a short window of time once a year I don't get the opportunity to do so much, only once every couple years or so. I picked some last winter but didn't get the chance to eat them while fresh...Hoping I can this time around.

Eating fresh mushrooms on the winter solstice is a tradition of mine :heart: .



but yea...woodlovers are no joke, they can be damn potent, and when fresh they have quite a zing to em'.

I still want to try azurescens, they are said to be a bit more potent than cyans or allenii. :crazy:






-OM

.


--------------------


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OfflineTyperwritermonky
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: openmind]
    #27073848 - 12/05/20 04:49 PM (3 years, 1 month ago)

25i is a terrible drug, but I'd be surprised if it "ruined your trips" unless you took a massive dose.  It's been found that 25i can actually damage the protein ligands and receptor sites and cause people to trip different forever at very high doses.  Heck, people were laying them 1mg standard per tab, and the most I ever took was like 450ug!


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OfflineAdas
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Typerwritermonky]
    #27113685 - 12/29/20 08:03 AM (3 years, 30 days ago)

Quote:

Typerwritermonky said:
It's been found that 25i can actually damage the protein ligands and receptor sites and cause people to trip different forever at very high doses.




From the perspective of someone who understands quite a bit of biology and medicine, this sounds like complete bullshit. It's just not possible as far as I know.


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InvisiblePsychoReactive
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Adas]
    #27116647 - 12/30/20 04:13 PM (3 years, 29 days ago)

Most wood loving muushrooms dominate cubensis and the likes. Psilocybe subaeruginosa and cyanenscens will be a heavy experience at large 2.5 grams dose.


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OfflineTyperwritermonky
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Registered: 01/19/12
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Adas]
    #27117062 - 12/30/20 08:37 PM (3 years, 28 days ago)

Quote:

Adas said:
Quote:

Typerwritermonky said:
It's been found that 25i can actually damage the protein ligands and receptor sites and cause people to trip different forever at very high doses.




From the perspective of someone who understands quite a bit of biology and medicine, this sounds like complete bullshit. It's just not possible as far as I know.




There are seriously dozens of articles on legit medical journals.  25i was made for a full agonist chemical to test serotonin pushes.  Overdoses cause serotonin toxidrome or even worse serotonin syndrome, which is absolute damage and reconfigurations of the serotonin receptors.  So yeah, getting either the toxidrome or syndrome will damage your serotonin receptors.

https://www.journalmc.org/index.php/JMC/article/view/2811/2154

This one goes over the extensive cellular toxicity of 25iNBOME in particular.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054380/



And then empirically, many users who have had 25i overdoses/heavy experiences that were negative have discussed that they find many drugs such as weed, or other psychedelics, to have affected them differently from before and after the 25i experience in question.  Considering the cellular toxicity, and chance for serotonin toxidrome - I would personally say that 25i can damage cellular receptor sites for a long time, if not permanently depending on the severity of overdose (see the kid from the journalmc article).

I'm not saying that the OP has that, I know nothing of his experience.  I am merely just suggesting it's a possibility.  Regardless, yes woodlovers are very potent and I am very happy to hear you feel that the mushroom trip healed the damage caused by 25i.


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OfflineLoaded Shaman
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Eclipse3130]
    #27117357 - 12/31/20 12:28 AM (3 years, 28 days ago)

Quote:

Eclipse3130 said:
Depending how big the one you ate was, I think you were more so just surprised of the potency. They are generally around twice the strength as most cubensis. Fresh ones 3x.

Fresh is always super potent, dried 1.5 - 2.5g is usually equivalent to 3.5 - 7g cubes if they really are extremely potent




I came into this thread to say this!


--------------------



"Real knowledge is to know the extent of one’s ignorance." — Confucius


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OfflineAdas
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Typerwritermonky]
    #27118700 - 12/31/20 03:56 PM (3 years, 28 days ago)

Quote:

Typerwritermonky said:
Quote:

Adas said:
Quote:

Typerwritermonky said:
It's been found that 25i can actually damage the protein ligands and receptor sites and cause people to trip different forever at very high doses.




From the perspective of someone who understands quite a bit of biology and medicine, this sounds like complete bullshit. It's just not possible as far as I know.




There are seriously dozens of articles on legit medical journals.  25i was made for a full agonist chemical to test serotonin pushes.  Overdoses cause serotonin toxidrome or even worse serotonin syndrome, which is absolute damage and reconfigurations of the serotonin receptors.  So yeah, getting either the toxidrome or syndrome will damage your serotonin receptors.

https://www.journalmc.org/index.php/JMC/article/view/2811/2154

This one goes over the extensive cellular toxicity of 25iNBOME in particular.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054380/



And then empirically, many users who have had 25i overdoses/heavy experiences that were negative have discussed that they find many drugs such as weed, or other psychedelics, to have affected them differently from before and after the 25i experience in question.  Considering the cellular toxicity, and chance for serotonin toxidrome - I would personally say that 25i can damage cellular receptor sites for a long time, if not permanently depending on the severity of overdose (see the kid from the journalmc article).

I'm not saying that the OP has that, I know nothing of his experience.  I am merely just suggesting it's a possibility.  Regardless, yes woodlovers are very potent and I am very happy to hear you feel that the mushroom trip healed the damage caused by 25i.




I've looked at them, but neither mentions actual nerotoxicity at the receptor level. Yes serotonin syndrome is a serious thing, but I've yet to see any evidence it does any long-term damage to neurons (in itself). So back to my original objection.. Still no evidence that it would "damage receptor sites". Besides, receptors as such don't matter and the neuron can quickly replace them. Toxic Leukoencephalopathy is something different - it's the demyelination of neurons. A completely different type of toxicity.


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OfflineTyperwritermonky
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Adas]
    #27118819 - 12/31/20 04:47 PM (3 years, 28 days ago)

Let's get this straight, I'm trying to say 25i is neurotoxic and can damage receptor sites.

Yeah the removal of myelin sheaths which are critical for nerve connections and communications at the level and speeds they need to... i'd call that neurological damage.

Also, not 25i, but 25c which is pretty much similar in effects, but less neurotoxic than 25i even.  Read this article, about the severity of the NEUROTOXICITY of the nBOMEs.

https://pubmed.ncbi.nlm.nih.gov/30806983/


also I've had serotonin toxidrome - it left me with terrible effects lasting about 6-8 months, and I couldn't smoke weed or anything.  The effects were awful and very different, even sober I felt like a retarded zombie.  It was probably the worst experience of my entire life.  So yeah after 8 months it healed, but I had a light toxidrome.  Those suffering serotonin syndrome are going to undergo much worse.

Serotonin syndrome causes receptor damage dude.. just google it there's dozens on the first page.  Here is an article about CNS/neurological damage.

https://academic.oup.com/painmedicine/article/4/1/63/1816666

So there's articles showing it causes CNS/neuro damage, as well as exerts heavy amounts of neurotoxicity - the most out of any drug ever studied (50x worse then meth).

Also I don't know why you are trying to stand up for 25nBOME or are trying to help people from thinking something bad has happened to them without ostensible proof but you're digging and asking for evidence that studies may have not been done on, but I don't think a single respectable chemist in the psychedelic area would try and say 25i is not neurotoxic.  It was developed to push serotonin levels past where they ever should go.  But if you look at all the studies suggesting the dangers of it, if you look at the actual severe cases where people had severe toxicity/death, and even if you just ask the community at large whose had negative experiences with 25i and whether or not they felt it led to lasting changes you'll get a clear answer that it's bad stuff.

And yeah dude I'm experienced, I ordered a gram of it over a decade ago.  I remember figuring out with tregar on other forums that HPBCD complexing made oral doses more possible which revolutionized the market and fueled it.  He and I were at the forefront when there was NO information so trust me dude.  25 nbomes are fucked and cause neurotoxicity and cellular site receptor damage.


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InvisiblecoAsTal
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Typerwritermonky]
    #27118886 - 12/31/20 05:20 PM (3 years, 28 days ago)

So since the thread has absolutely nothing to do with those garbage chems, let me just get it back on track and say that I have an awesome plate of Ps. Cyan on agar right now-- and I can't wait to confirm OP's story with a live woody of my own :hug:

:mushroom2:


--------------------
I am certain of nothing but the holiness of the Heart's affections and the truth of Imagination--  John Keats

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OfflineAdas
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: Typerwritermonky]
    #27118920 - 12/31/20 05:43 PM (3 years, 28 days ago)

Quote:

Typerwritermonky said:
Let's get this straight, I'm trying to say 25i is neurotoxic and can damage receptor sites.

Yeah the removal of myelin sheaths which are critical for nerve connections and communications at the level and speeds they need to... i'd call that neurological damage.

Also, not 25i, but 25c which is pretty much similar in effects, but less neurotoxic than 25i even.  Read this article, about the severity of the NEUROTOXICITY of the nBOMEs.

https://pubmed.ncbi.nlm.nih.gov/30806983/


also I've had serotonin toxidrome - it left me with terrible effects lasting about 6-8 months, and I couldn't smoke weed or anything.  The effects were awful and very different, even sober I felt like a retarded zombie.  It was probably the worst experience of my entire life.  So yeah after 8 months it healed, but I had a light toxidrome.  Those suffering serotonin syndrome are going to undergo much worse.

Serotonin syndrome causes receptor damage dude.. just google it there's dozens on the first page.  Here is an article about CNS/neurological damage.

https://academic.oup.com/painmedicine/article/4/1/63/1816666

So there's articles showing it causes CNS/neuro damage, as well as exerts heavy amounts of neurotoxicity - the most out of any drug ever studied (50x worse then meth).

Also I don't know why you are trying to stand up for 25nBOME or are trying to help people from thinking something bad has happened to them without ostensible proof but you're digging and asking for evidence that studies may have not been done on, but I don't think a single respectable chemist in the psychedelic area would try and say 25i is not neurotoxic.  It was developed to push serotonin levels past where they ever should go.  But if you look at all the studies suggesting the dangers of it, if you look at the actual severe cases where people had severe toxicity/death, and even if you just ask the community at large whose had negative experiences with 25i and whether or not they felt it led to lasting changes you'll get a clear answer that it's bad stuff.

And yeah dude I'm experienced, I ordered a gram of it over a decade ago.  I remember figuring out with tregar on other forums that HPBCD complexing made oral doses more possible which revolutionized the market and fueled it.  He and I were at the forefront when there was NO information so trust me dude.  25 nbomes are fucked and cause neurotoxicity and cellular site receptor damage.




To get it straight (and get this debate over with), I'm by no means advocating NBOMe use, nor saying it is not neurotoxic in some way. Having bad lasting effects is of course possible.

Now I think I have to say this again since it looks like you misunderstood: "receptor damage" in and of itself is not only impossible with these compounds (they would have to physically destroy the receptor) - it also wouldn't be a big deal. Since receptors are always being replaced by new ones. What happens to the NEURON is a different thing. Yes excitotoxicity is a thing and can occur from many different causes. All I'm doing is correcting you on the terminology (I'm someone with a bit of a background in medicine so it makes me a bit nitpicky. I apologize if it sounds argumentative)

I hope this makes it clear :smile: Peace!


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Offline99.99
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Re: Psilocybe Cyanescens Surprisingly Potent? [Re: coAsTal] * 1
    #27119071 - 12/31/20 06:53 PM (3 years, 28 days ago)

Quote:

coAsTal said:
So since the thread has absolutely nothing to do with those garbage chems, let me just get it back on track and say that I have an awesome plate of Ps. Cyan on agar right now-- and I can't wait to confirm OP's story with a live woody of my own :hug:

:mushroom2:




😁
As do i


My grow log
https://www.shroomery.org/forums/showflat.php/Number/27012634/fpart/all


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