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OfflineSabnock
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Re: Increasing bioavailability of psilocybin or how to trip hard on less [Re: Cyrilion]
    #27008763 - 10/28/20 04:25 PM (3 years, 3 months ago)

Quote:

Cyrilion said: I have read in several places that MAOI can increase the negative effects of psychedelics, but i have no idea how prevalent that is or how true or all encompassing it is, and as i generally use mushrooms as a mood stabilizer for my mental health first and as a recreational activity second i'm not too keen to mix MAOI's into it personally, and so i would suggest leaving those till last, reading other peoples experiences and then slowly upping the amount you take to see how much you can handle without excessive negative consequences. Again, i am not experienced with MAOI, i only know what i know about them from reading, i have no first hand experience, but lots of people do and likely are willing to help you or anyone else out in finding a correct methodology with them.




The MAO-A inhibition definitely doesn't increase the negatives, if anything, it reduces the negatives. The only negative i can see is due to the potentiation of the Psychedelic dosage which can lead people into more of a mentally challenging trip, so due to potentiation, better to start lower on the dosage for the Psychedelic side. Harmalas actually have relaxant and anti-anxiety properties in higher dosages, and provides a more clearheaded/sober-ish kind of experience, which imo makes the Psychedelic more user-friendly and more positive. Ime with Ayahuasca and Psilohuasca, i find Psilohuasca to be a lot more relaxed/gentler/less intense than Aya, still as powerful as Aya, just that Psilocin is not as intense as the DMT. Trust me, i have plenty of experience with the Huasca's, it's nowhere near as bad as people think.


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