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OfflineDH888
Stranger
Registered: 08/26/18
Posts: 18
Last seen: 3 years, 2 months
A question about microdosing while on SSRI's
    #26979859 - 10/11/20 11:23 AM (3 years, 3 months ago)

Hello, I am interested in trying the Stamets stack protocol of psilocybin, niacin, and lions mane. But I am currently on cymbalta for depression. I realize that SSRI's basically blunt the psychoactive effects of mushrooms (at least in my case they did), but on a microdose I'm not expecting to trip anyway. Would I still get other non-psychoactive benefits from psilocybin? My ideal goal is to get off of SSRI's and use microdosing for depression. Thanks.


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InvisibleRhizomorph
Psychedelic Researcher
Other


Registered: 04/24/20
Posts: 785
Re: A question about microdosing while on SSRI's [Re: DH888]
    #26996867 - 10/21/20 07:04 PM (3 years, 3 months ago)

As a student of psychedelic science, I'm of the belief that the psychoactive effects themselves are what provides the therapeutic effects. Some companies are trying to make non-psychoactive psychedelics that provide the same benefits but I just don't think that is possible.

Even though you may not feel the effects consciously, microdosing can have sub-perceptual psychoactive effects that I believe are what cause their purported benefits.

Unfortunately there is not a lot of research on this yet though - most microdosing studies are currently focusing on the effects of microdosing in the average population, without testing the influence of other factors, such as other drugs (SSRI's) thrown into the mix. And even these aren't conclusive.

You can give it a try and see if it works for you. I can't recommend going off of SSRI's, but you could consider it with your doctor if you really wanted.

I'm of the belief that mild to moderate depression is better treated by macro-dosing in a controlled setting(e.g. with a therapist or trusted loved one), but further research on microdosing may prove this otherwise. SSRI's don't really solve the root of the issue, they just alter neurotransmitters, namely serotonin, so that symptoms of depression (but oftentimes mood in general) is blunted.

Psychedelics actually increase the brain's sensitivity to emotions and blunt the ego, causing the lines between the conscious and unconscious to be less strict. This allows one to explore and address the deep roots of depression that exist within the unconscious part of the psyche. However, microdoses generally don't have a great enough effect size to allow for this. As such, they usually just speed up the nervous system which increases the speed of thinking, focus, etc. which can be helpful for some, but don't really address the deeper issue, similar to SSRI's.

As I said this isn't tested true, it is just my hypothesis based on what I know as a student. I'm no expert however. I know this doesn't directly answer your question but I hope it helps somehow.


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:cookiemonster: Major Issues in the Psychedelic Movement: Why 'Psychedelic People' and the Psychedelic Movement Sucks:elmo:

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Offlinerustygrape
the great perhaps
Female User Gallery

Registered: 12/20/10
Posts: 229
Last seen: 1 year, 2 months
Re: A question about microdosing while on SSRI's [Re: Rhizomorph]
    #27004475 - 10/26/20 11:39 AM (3 years, 3 months ago)

Hi Rhizomorph , are there universities or programs one can get involve with to be a student of psychedelic science? That kind of work sounds really interesting and beneficial for society


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InvisibleRhizomorph
Psychedelic Researcher
Other


Registered: 04/24/20
Posts: 785
Re: A question about microdosing while on SSRI's [Re: rustygrape]
    #27004580 - 10/26/20 12:41 PM (3 years, 3 months ago)

Hey rustygrape,

There are graduate programs available to do psychedelic science, but they are somewhat limited. Most of them require you to get some more generalized undergraduate training such as in psychology, neurochemistry, or even social work could get you into similar fields (the main difference between them is the extent you want to be working with people directly versus conducting research. Each has implications for psychedelic science & therapy though). Medicine could even get you a role working with psychedelics, but I'd say psychology and neurochemistry tend to be the focus of psychedelic science today.

I also recommend you read this article by MAPS, although it might be a bit dated by now. The psychedelic renaissance is growing fast and psychedelic science is becoming more widely available & accepted - you probably don't need to take so much of a "lay low & infiltrate the system" approach as recommended in the article. It's still a good read nonetheless:

https://maps.org/resources/students/181-so-you-want-to-be-a-psychedelic-researcher

Are you a US citizen/Canadian citizen? I may be able to point you towards more specific programs if I know which country you're from.

It's definitely a very interesting & emerging field with lots of opportunity. I'm glad to see others are interested in it as well :grin:


--------------------

:cookiemonster: Major Issues in the Psychedelic Movement: Why 'Psychedelic People' and the Psychedelic Movement Sucks:elmo:

:awesomenod: Easiest No-Pour Agar Method: Alien's Holy Grail No pour Agar unmodified containers:awesomenod:


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