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Offlinekuutar
bitchy moon goddess
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Registered: 09/08/20
Posts: 6
Last seen: 3 months, 10 days
shrooms after duodenal switch?
    #26931045 - 09/12/20 12:37 AM (3 years, 4 months ago)

Hi everyone! I am planning to have a bariatric procedure called a duodenal switch, it's like a gastric bypass except they bypass even more of the intestine so the reduction in nutrition absorbed is even greater.

Friends who have had a gastric bypass tell me that alcohol hits them several times harder and faster than before. i searched some of the comments here and folks seem to suggest that shrooms might be the same.

I was just wondering however if anyone has had the duodenal switch procedure.

It's still several months off for me and i should have my first grow and first "test pilot" trip (I am a comnplete n00b) done before then, and hopefully also a second trip during which i hope to try the "heroic dose" before such a thing might not be possible due to the modifications in my digestive system.

For my first grow I am planning to use the "gordo tek" method and will powder and capsulize my harvest. I figured it would be useful for a variety of methods of administration.

For after the procedure, do acidic soluitions of shroom powder (what I understand to be called "lemon tek") really do anything to enhance absorption of the psilocybin?

Someone in a post jokingly suggested administering a dose ummm... rectally. I actually have no issue with considering this (lol i'm queer so it sounds kinda fun to be honest) but has anyone actually done that, and how do rectally administered doses compare to oral? I would think it would be a bit less if you took it in your bum.

Anyhow, thanks for your insight! Kiitos! :smile:


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OfflineMentalPariah
Pariah of my mind


Registered: 03/18/18
Posts: 3,903
Last seen: 25 days, 22 hours
Re: shrooms after duodenal switch? [Re: kuutar]
    #26931306 - 09/12/20 07:19 AM (3 years, 4 months ago)

first of all, best of luck with your upcoming procedure!

Im gonna jump right into this.
So its true that nutrient absorption will be greatly decreased, so with that alcohol tolerance will be too. This is because a percentage of the alcohol will be bypassing the liver first pass and the "toxic" effects will be greatly increased... the liver is acting as a filter in this case. Now, with psilocybin its different. Psilocybin must be de-phosphorated in order to become bioavailable, it does this in the liver as well but using an enzyme group called alkaline phosphatase. Removing the phosphate from 4-HO-PO-DMT converts it to psilocin or 4-HO-DMT which is the hallucinogenic chemical.
This isn't the only way though, acids will remove the phosphate as well, Lemon juice is great at this. While it won't fully convert it will convert a large percent. If I was in your shoes I would probably make a strong tea using lemon juice or other weak acid and boil down to a small amount.


Want to add for accuracy. When I say the liver is acting as a filter with alcohol, I mean that alcohol dehydrogenase Converts it into non bioactive compounds...not physically only filtered out.


Edited by MentalPariah (09/12/20 07:24 AM)


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OfflinePrimalSoup
hyperspatial illuminations
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Registered: 11/17/09
Posts: 13,568
Loc: PNW Flag
Last seen: 1 year, 5 months
Re: shrooms after duodenal switch? [Re: kuutar]
    #26931908 - 09/12/20 02:08 PM (3 years, 4 months ago)

Quote:

kuutar said:
It's still several months off for me and i should have my first grow and first "test pilot" trip (I am a comnplete n00b) done before then, and hopefully also a second trip during which i hope to try the "heroic dose" before such a thing might not be possible due to the modifications in my digestive system.

For my first grow I am planning to use the "gordo tek" method and will powder and capsulize my harvest. I figured it would be useful for a variety of methods of administration.

For after the procedure, do acidic soluitions of shroom powder (what I understand to be called "lemon tek") really do anything to enhance absorption of the psilocybin?






I had part of my large intestine removed and a stomach valve bypass as well years ago due to cancer but aside from an intolerance to sucrose it never affected tripping.  So you'll probably be fine.

But the other part is if you grow them make tea instead, this will help to preserve the psilocin and if you make the tea acidified it improves the bio-availability of the actives by attaching citrate molecules to them (this is also what lemon tek does, those low levels of acidity are not capable of dephosphorlyzing psilocybin).  Also the tea will be easier to digest than the dried mushrooms and reduce nausea to negligible levels.  If you make a large batch from your grow it will homogenize it as well.  And you can freeze it for storage. :cookiemonster:


--------------------

if you stand too close to the machine it'll start to eat you
Primal's simple tested teks and projects: :awesomenod: Wheat Prep 2.0  Acidic Tea Tek  Potency Project! 


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