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gopher
Coffee Bean Extraordinaire



Registered: 11/22/17
Posts: 13,173
Loc: Canada
Last seen: 1 hour, 2 minutes
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All diabetes drugs suck
#26925073 - 09/08/20 06:02 PM (3 years, 5 months ago) |
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Any drug that raises insulin sucks, because they will make you fat when you need to lose weight while increasing insulin resistance making your diabetes worse, so sulfonylurea's and insulin itself is out (I wonder why insulin is a last resort drug, they know it dosnt work, but they are so focused on treating the symptom of high blood sugar, when its a dietary disease )
sglt2 inhibitors sound ace to me in theory, they block the reabsorption of glucose in the kidneys and you piss it out, I started wondering why they arnt the first choice in treatment till I looked up the side effects and holy shit, I like having my toes
so I was left thinking metformin is the best one,because I didnt understand how it lowered glucose, and it dosnt have horrible side effects, and there is probably a reason its the first choice of treatment, but just now I found out it works by blocking gluconeogenesis (your liver turning proteins into glucose) so you are 100% dependant in getting your glucose from food if you are on metformin, I would assume if you forgot to eat for about 36 hours on metformin you would burn through all your glycogen and then go hypoglycemic cause you cant produce any glucose internally
I think all diabetes drugs suck, I really want to like sglt2 inhibitors because of their mode of action, but I would never take them myself due to the serious side effects
-------------------- For most of the normies out there, an operating system is just a bootloader for Google Chrome. Since Disney has obtained tremendous value from the public domain, knows how important the public domain is, and is firmly determined to never contribute anything to it. My pronouns are He and Him, and my adjectives are Fat and Jazzy
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CookieCrumbs
Fucked off to the pub


Registered: 12/10/11
Posts: 14,151
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Re: All diabetes drugs suck [Re: gopher]
#26925141 - 09/08/20 06:37 PM (3 years, 5 months ago) |
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Dude any disease where the digestive system essentially gives up fucking sucks.
Trying to treat that fucking sucks. It's the most complicated system in the human body excepting maybe the nervous system and it's real hard to fuck with it without fucking it.
Ask my dead gallbladder and my half dead liver and my hysteria prone guts.
Took me about 20 years of smaller issues, bad diet, and drugs to completely fuck them and it's pretty certain I'm never gonna unfuck them. Only thing I can do is try to deal with their shortcomings.
Which is largely what diabetes management tries to do.
I think you're better off losing a limb than seriously fucking your digestive system.
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Free time is the only time
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PumpJackTeX
livin life



Registered: 05/26/08
Posts: 3,951
Loc: California
Last seen: 11 months, 17 days
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Celiac got me good.
-------------------- Life. 2008 Ascension Energy | UFOs | 2021
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gopher
Coffee Bean Extraordinaire



Registered: 11/22/17
Posts: 13,173
Loc: Canada
Last seen: 1 hour, 2 minutes
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Im not even celiac, but I got pissed off when the pepperoni I bought contained wheat when I read the ingredients when I got home
-------------------- For most of the normies out there, an operating system is just a bootloader for Google Chrome. Since Disney has obtained tremendous value from the public domain, knows how important the public domain is, and is firmly determined to never contribute anything to it. My pronouns are He and Him, and my adjectives are Fat and Jazzy
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Ice9
3X Ban Lotto Champion



Registered: 03/20/14
Posts: 11,320
Loc: daterapeville,USA
Last seen: 19 minutes, 56 seconds
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Re: All diabetes drugs suck [Re: gopher] 1
#26925317 - 09/08/20 08:50 PM (3 years, 5 months ago) |
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Quote:
gopher said: Any drug that raises insulin sucks, because they will make you fat when you need to lose weight while increasing insulin resistance making your diabetes worse, so sulfonylurea's and insulin itself is out (I wonder why insulin is a last resort drug, they know it dosnt work, but they are so focused on treating the symptom of high blood sugar, when its a dietary disease )
sglt2 inhibitors sound ace to me in theory, they block the reabsorption of glucose in the kidneys and you piss it out, I started wondering why they arnt the first choice in treatment till I looked up the side effects and holy shit, I like having my toes
so I was left thinking metformin is the best one,because I didnt understand how it lowered glucose, and it dosnt have horrible side effects, and there is probably a reason its the first choice of treatment, but just now I found out it works by blocking gluconeogenesis (your liver turning proteins into glucose) so you are 100% dependant in getting your glucose from food if you are on metformin, I would assume if you forgot to eat for about 36 hours on metformin you would burn through all your glycogen and then go hypoglycemic cause you cant produce any glucose internally
I think all diabetes drugs suck, I really want to like sglt2 inhibitors because of their mode of action, but I would never take them myself due to the serious side effects
Emphasis mine. It's well established fact that giving a patient a pill, or a shot everyday will have a much higher rate of compliance than asking them to make drastic lifestyle changes. It's sad but it's true.
-------------------- The reasonable man adapts himself to the world; the unreasonable one persists in trying to adapt the world to himself. Therefore, all progress depends on the unreasonable man. -- George Brenard Shaw
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jerrymor
Stranger
Registered: 01/20/22
Posts: 45
Last seen: 1 year, 23 days
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Re: All diabetes drugs suck [Re: gopher]
#28110961 - 12/24/22 10:51 AM (1 year, 1 month ago) |
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Diabetes is sucks, not the meds
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trees


Registered: 02/08/09
Posts: 9,202
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Re: All diabetes drugs suck [Re: jerrymor] 1
#28110979 - 12/24/22 11:10 AM (1 year, 1 month ago) |
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People refuse to understand that eating bread and wheat based and starchy foods is worse for insulin resistance and poor metabolic health than eating straight spoonfulls of table sugar. They just do not have the neurological facilities to comprehend that fact.
And so they will express praise for miracle pills like metformin allowing them to rationalize subsisting on pure glucose.
No change in lifestyle, only magic pills.
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Smellyhobbit
Actual Retard



Registered: 04/01/22
Posts: 11,429
Loc: Hole
Last seen: 1 minute, 4 seconds
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Re: All diabetes drugs suck [Re: gopher]
#28111407 - 12/24/22 07:17 PM (1 year, 1 month ago) |
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Simple carbohydrates metabolize rapidly into glucose. Bread, pasta, baked goods - anything with flour.
Eat Whole Foods. Cook things for yourself.
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Anahata


Registered: 02/25/12
Posts: 2,399
Last seen: 21 days, 4 hours
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Re: All diabetes drugs suck [Re: gopher]
#28111571 - 12/24/22 10:20 PM (1 year, 1 month ago) |
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I think you just need a hug.
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pepz
Stranger


Registered: 12/20/22
Posts: 68
Last seen: 1 year, 1 month
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Re: All diabetes drugs suck [Re: Anahata]
#28111577 - 12/24/22 10:26 PM (1 year, 1 month ago) |
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Im reading hashimoto protocol right now, stupid siblings suffer from autoimmune so Im trying to stay ahead of it. Might help though. Of course I couldnt imagine them reading it though(too busy being fake).
-------------------- Eluding is run by dumb nazis that work for the state, I know cause I was there when they stole my software. If I know who they are, than so does the state.
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