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OfflineYugambeh
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Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis
    #26878187 - 08/13/20 10:00 AM (3 years, 5 months ago)



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I am like a white cloud with no destination, I place goals to trick myself in believing I have somewhere to arrive, everything is a successful goal when I realise I have already arrived.


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InvisibleAsante
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Yugambeh]
    #26878191 - 08/13/20 10:03 AM (3 years, 5 months ago)

Cause the tiiiimes they are a-changin' :raisemyglass:

Kilogram scale pilot batch of scalable PHARMACEUTICAL PSILOCYBIN synthesis.


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Omnicyclion.org
higher knowledge starts here


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Offlinespirit_shadow
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Registered: 08/15/11
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante]
    #26878235 - 08/13/20 10:34 AM (3 years, 5 months ago)

Wtf...how do you synthesize psilocybin? What do they synth it from?


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ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011
Ban lotto


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Offlinechristopera
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: spirit_shadow]
    #26878243 - 08/13/20 10:39 AM (3 years, 5 months ago)

Yeah, this seems like an advertisement not a proof of process.


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Enjoy the process of your search without succumbing to the pressure of the result.

A Dorito is pizza, change my mind.

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InvisibleAsante
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: spirit_shadow]
    #26878259 - 08/13/20 10:47 AM (3 years, 5 months ago)

Quote:

spirit_shadow said:
Wtf...how do you synthesize psilocybin? What do they synth it from?





Good question but logically, 4-hydroxyindole with the hydroxy group protected.

I know the old synth was an explosive hazard.

My guess is something modern and innovative.


--------------------
Omnicyclion.org
higher knowledge starts here


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Offlinespirit_shadow
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante]
    #26878371 - 08/13/20 11:42 AM (3 years, 5 months ago)

Oh now it all makes sense :p.....where does 4-hydroxyindole come from?


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ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011
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InvisibleAsante
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: spirit_shadow]
    #26878401 - 08/13/20 12:02 PM (3 years, 5 months ago)

If you heat a mixture of 3-hydroxyphenylhydrazine (regular catalog chem) with acetaldehyde you get a mixture of 4-hydroxyindole and 6-hydroxyindole which you can separate.

4-hydroxyindole can make psilocin analogs

6-hydroxyindole can make harmaline analogs


--------------------
Omnicyclion.org
higher knowledge starts here


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Offlinespirit_shadow
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante] * 1
    #26878609 - 08/13/20 01:46 PM (3 years, 5 months ago)

You are a genius.....you inspire me. If I survive this pandemic and persue my dreams and go back to college I want to learn chemistry BAD. I want to know HOW this reality works as best as I can.


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ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011
Ban lotto


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Invisiblebadchad
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Registered: 03/02/05
Posts: 13,372
Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: spirit_shadow] * 1
    #26878716 - 08/13/20 02:28 PM (3 years, 5 months ago)

The paper is linked, and describes the methodology.

Chemistry papers remind me why I pursued pharmacology.


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...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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Offlinespirit_shadow
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: badchad]
    #26879034 - 08/13/20 06:22 PM (3 years, 5 months ago)

So is the end result the EXACT chemical found in cubes?


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ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011
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OfflinePatlal
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante] * 1
    #26879105 - 08/13/20 07:05 PM (3 years, 5 months ago)

Quote:

Asante said:
If you heat a mixture of 3-hydroxyphenylhydrazine (regular catalog chem) with acetaldehyde you get a mixture of 4-hydroxyindole and 6-hydroxyindole which you can separate.

4-hydroxyindole can make psilocin analogs

6-hydroxyindole can make harmaline analogs




I love to condratict you but this time...

:ifyoucanawe:


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InvisibleThe Blind Ass
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Registered: 08/16/16
Posts: 26,657
Loc: The Primordial Mind
Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante]
    #26879355 - 08/13/20 10:53 PM (3 years, 5 months ago)

Quote:

Asante said:
Cause the tiiiimes they are a-changin' :raisemyglass:

Kilogram scale pilot batch of scalable PHARMACEUTICAL PSILOCYBIN synthesis.




:zomgzomgzomg:


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Give me Liberty caps -or- give me Death caps


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InvisibleAsante
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Patlal]
    #26879463 - 08/14/20 01:47 AM (3 years, 5 months ago)

Quote:

Patlal said:
Quote:

Asante said:
If you heat a mixture of 3-hydroxyphenylhydrazine (regular catalog chem) with acetaldehyde you get a mixture of 4-hydroxyindole and 6-hydroxyindole which you can separate.

4-hydroxyindole can make psilocin analogs

6-hydroxyindole can make harmaline analogs




I love to condratict you but this time...

:ifyoucanawe:





The Fisher Indole Synthesis bruh.

https://en.wikipedia.org/wiki/Fischer_indole_synthesis


--------------------
Omnicyclion.org
higher knowledge starts here


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Invisibledeucedbi9
Stranger

Registered: 10/24/06
Posts: 4,594
Loc: UK
Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante]
    #26879572 - 08/14/20 05:32 AM (3 years, 5 months ago)

Quote:

Asante said:
Quote:

Patlal said:
Quote:

Asante said:
If you heat a mixture of 3-hydroxyphenylhydrazine (regular catalog chem) with acetaldehyde you get a mixture of 4-hydroxyindole and 6-hydroxyindole which you can separate.

4-hydroxyindole can make psilocin analogs

6-hydroxyindole can make harmaline analogs




I love to condratict you but this time...

:ifyoucanawe:





The Fisher Indole Synthesis bruh.

https://en.wikipedia.org/wiki/Fischer_indole_synthesis




Oh well, time to give the ole saucepans a good scrub.


:lol:


--------------------
whether low pressure sucks or high pressure blows...
it's a bugger to cycle in.

even though I'm feeling good
Something tells me I'd better activate my prayer capsule


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