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Yugambeh
Stranger



Registered: 02/18/20
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Loc: England/Peak District
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Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis
#26878187 - 08/13/20 10:00 AM (3 years, 5 months ago) |
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-------------------- I am like a white cloud with no destination, I place goals to trick myself in believing I have somewhere to arrive, everything is a successful goal when I realise I have already arrived.
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Asante
Mage


Registered: 02/06/02
Posts: 86,795
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Yugambeh]
#26878191 - 08/13/20 10:03 AM (3 years, 5 months ago) |
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Cause the tiiiimes they are a-changin' 
Kilogram scale pilot batch of scalable PHARMACEUTICAL PSILOCYBIN synthesis.
-------------------- Omnicyclion.org higher knowledge starts here
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spirit_shadow
Feature not a bug



Registered: 08/15/11
Posts: 25,665
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante]
#26878235 - 08/13/20 10:34 AM (3 years, 5 months ago) |
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Wtf...how do you synthesize psilocybin? What do they synth it from?
-------------------- ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011 Ban lotto
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christopera
Stranger


Registered: 10/13/17
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: spirit_shadow]
#26878243 - 08/13/20 10:39 AM (3 years, 5 months ago) |
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Yeah, this seems like an advertisement not a proof of process.
-------------------- Enjoy the process of your search without succumbing to the pressure of the result. A Dorito is pizza, change my mind. Bank and Union with The Shroomery at the Zuul on The internet - now with %'s and things I’m sorry it had to be me.
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Asante
Mage


Registered: 02/06/02
Posts: 86,795
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: spirit_shadow]
#26878259 - 08/13/20 10:47 AM (3 years, 5 months ago) |
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Quote:
spirit_shadow said: Wtf...how do you synthesize psilocybin? What do they synth it from?
Good question but logically, 4-hydroxyindole with the hydroxy group protected.
I know the old synth was an explosive hazard.
My guess is something modern and innovative.
-------------------- Omnicyclion.org higher knowledge starts here
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spirit_shadow
Feature not a bug



Registered: 08/15/11
Posts: 25,665
Last seen: 1 hour, 49 minutes
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante]
#26878371 - 08/13/20 11:42 AM (3 years, 5 months ago) |
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Oh now it all makes sense :p.....where does 4-hydroxyindole come from?
-------------------- ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011 Ban lotto
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Asante
Mage


Registered: 02/06/02
Posts: 86,795
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: spirit_shadow]
#26878401 - 08/13/20 12:02 PM (3 years, 5 months ago) |
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If you heat a mixture of 3-hydroxyphenylhydrazine (regular catalog chem) with acetaldehyde you get a mixture of 4-hydroxyindole and 6-hydroxyindole which you can separate.
4-hydroxyindole can make psilocin analogs
6-hydroxyindole can make harmaline analogs
-------------------- Omnicyclion.org higher knowledge starts here
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spirit_shadow
Feature not a bug



Registered: 08/15/11
Posts: 25,665
Last seen: 1 hour, 49 minutes
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante] 1
#26878609 - 08/13/20 01:46 PM (3 years, 5 months ago) |
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You are a genius.....you inspire me. If I survive this pandemic and persue my dreams and go back to college I want to learn chemistry BAD. I want to know HOW this reality works as best as I can.
-------------------- ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011 Ban lotto
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badchad
Mad Scientist

Registered: 03/02/05
Posts: 13,372
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: spirit_shadow] 1
#26878716 - 08/13/20 02:28 PM (3 years, 5 months ago) |
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The paper is linked, and describes the methodology.
Chemistry papers remind me why I pursued pharmacology.
-------------------- ...the whole experience is (and is as) a profound piece of knowledge. It is an indellible experience; it is forever known. I have known myself in a way I doubt I would have ever occurred except as it did. Smith, P. Bull. Menninger Clinic (1959) 23:20-27; p. 27. ...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely. Osmond, H. Annals, NY Acad Science (1957) 66:418-434; p.436
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spirit_shadow
Feature not a bug



Registered: 08/15/11
Posts: 25,665
Last seen: 1 hour, 49 minutes
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: badchad]
#26879034 - 08/13/20 06:22 PM (3 years, 5 months ago) |
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So is the end result the EXACT chemical found in cubes?
-------------------- ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011 Ban lotto
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Patlal
You ask too many questions



Registered: 10/09/10
Posts: 44,797
Loc: Ottawa
Last seen: 4 hours, 33 minutes
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante] 1
#26879105 - 08/13/20 07:05 PM (3 years, 5 months ago) |
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Quote:
Asante said: If you heat a mixture of 3-hydroxyphenylhydrazine (regular catalog chem) with acetaldehyde you get a mixture of 4-hydroxyindole and 6-hydroxyindole which you can separate.
4-hydroxyindole can make psilocin analogs
6-hydroxyindole can make harmaline analogs
I love to condratict you but this time...
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The Blind Ass
Bodhi



Registered: 08/16/16
Posts: 26,657
Loc: The Primordial Mind
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante]
#26879355 - 08/13/20 10:53 PM (3 years, 5 months ago) |
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Quote:
Asante said: Cause the tiiiimes they are a-changin' 
Kilogram scale pilot batch of scalable PHARMACEUTICAL PSILOCYBIN synthesis.
-------------------- Give me Liberty caps -or- give me Death caps
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Asante
Mage


Registered: 02/06/02
Posts: 86,795
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Patlal]
#26879463 - 08/14/20 01:47 AM (3 years, 5 months ago) |
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Quote:
Patlal said:
Quote:
Asante said: If you heat a mixture of 3-hydroxyphenylhydrazine (regular catalog chem) with acetaldehyde you get a mixture of 4-hydroxyindole and 6-hydroxyindole which you can separate.
4-hydroxyindole can make psilocin analogs
6-hydroxyindole can make harmaline analogs
I love to condratict you but this time...

The Fisher Indole Synthesis bruh.
https://en.wikipedia.org/wiki/Fischer_indole_synthesis
-------------------- Omnicyclion.org higher knowledge starts here
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deucedbi9
Stranger

Registered: 10/24/06
Posts: 4,594
Loc: UK
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Re: Usona Institute Publishes Breakthrough Development in Scalable Psilocybin Synthesis [Re: Asante]
#26879572 - 08/14/20 05:32 AM (3 years, 5 months ago) |
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Quote:
Asante said:
Quote:
Patlal said:
Quote:
Asante said: If you heat a mixture of 3-hydroxyphenylhydrazine (regular catalog chem) with acetaldehyde you get a mixture of 4-hydroxyindole and 6-hydroxyindole which you can separate.
4-hydroxyindole can make psilocin analogs
6-hydroxyindole can make harmaline analogs
I love to condratict you but this time...

The Fisher Indole Synthesis bruh.
https://en.wikipedia.org/wiki/Fischer_indole_synthesis
Oh well, time to give the ole saucepans a good scrub.
-------------------- whether low pressure sucks or high pressure blows... it's a bugger to cycle in. even though I'm feeling good Something tells me I'd better activate my prayer capsule
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