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OfflineTheBlindHarper
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Microdosing with Psilocybin analogues - 4-ACO-DMT etc
    #26869895 - 08/08/20 11:12 AM (3 years, 5 months ago)

Has anyone ever tried microdosing with Psilocybin analogues, and found effects similar to microdosing with real mushrooms?

I personally, in my uneducated mind, don't think they would have the same potential as true mushroom matter, but I'm interested to hear other peoples experiences.


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OfflineShroomhunts
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Re: Microdosing with Psilocybin analogues - 4-ACO-DMT etc [Re: TheBlindHarper]
    #26870586 - 08/08/20 08:04 PM (3 years, 5 months ago)

Anything that comes out a slab isn't going to contain the same blend of sacred psychedelic as psilocybin mushrooms.


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OfflineSabnock
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Re: Microdosing with Psilocybin analogues - 4-ACO-DMT etc [Re: Shroomhunts]
    #26870683 - 08/08/20 09:07 PM (3 years, 5 months ago)

4-ACO turns into Psilocin in the body, so it should have the same benefits, near about, as microdosing mushrooms or pure Psilocybin. Though with 4-ACO since it's in a pure powder form it'll likely last a little shorter in duration than consuming a capsule of microdosed mushroom powder, for example, though one could bake their 4-ACO microdose into an edible of some form like a cookie. One thing one could try, is taking a dose of Syrian Rue or B. Caapi or Harmala extracts, or Moclobemide, and then take the microdose of 4-ACO (or mushrooms) but a longer duration and potentiated effect (so be sure to account for the need to decrease one's microdose dosage). One thing i like about the 4-ACO and MAO-A inhibition combination, is that 4-ACO's metabolism into Psilocin is way more pronounced and noticeable, compared to 4-ACO on it's own, feels near identical to mushrooms with MAO-A inhibition to me personally, but i haven't yet investigated the microdosing thing yet.


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Invisibleredgreenvines
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Re: Microdosing with Psilocybin analogues - 4-ACO-DMT etc [Re: TheBlindHarper] * 2
    #26871595 - 08/09/20 01:04 PM (3 years, 5 months ago)

i think when you use Psilocybin analogues - 4-ACO-DMT etcyou are ahead of the game as regards measured dosage - it is much easier to accurately repeat the dosage that works best for you this way - leaving less up to the vagaries of chance as to whether you get too much noticeable effect or no benefit at all.


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Invisiblelarry.fisherman
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Re: Microdosing with Psilocybin analogues - 4-ACO-DMT etc [Re: Shroomhunts] * 1
    #26871781 - 08/09/20 03:16 PM (3 years, 5 months ago)

Quote:

Shroomhunts said:
Anything that comes out a slab isn't going to contain the same blend of sacred psychedelic as psilocybin mushrooms.



What is sacred? Is it symbolic or is it of utter importance? I think molecules are as basic as things get. They're essential and kind of timeless. They are the Lego blocks of our Lego world. Why can't a molecule be a god?


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OfflineShroomhunts
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Re: Microdosing with Psilocybin analogues - 4-ACO-DMT etc [Re: larry.fisherman]
    #26871811 - 08/09/20 03:35 PM (3 years, 5 months ago)

Our ancestors have been using these mushrooms for thousands of years. They have been here long before you were born and will be here long after you are dead. Sacred natural entheogens.


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InvisibleRhizomorph
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Registered: 04/24/20
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Re: Microdosing with Psilocybin analogues - 4-ACO-DMT etc [Re: TheBlindHarper] * 1
    #26871831 - 08/09/20 03:49 PM (3 years, 5 months ago)

I micro-dosed about 1mg of 4-Aco-DMT for a few months last year and found it to be almost identical to micro-dosing mushrooms.

This makes sense given that it is likely a prodrug for psilocin, which is what psilocybin also metabolizes into. Even if it is active on its own the effects of 4-Aco-DMT are extremely similar to psilocybin (4-HO-DMT) and hit all the same receptor sites as psilocybin. I can't see how there would be much difference that you or I could tell even if there are subtle pharmacological differences.

For anyone who decides to try it, I recommend volumetrically dosing since, unless you have a very expensive scale, most scales aren't very good at measuring below 10-15mg. My scale which can reliably measure 20mg if I want has a +/-5mg error at measurements below 10-15mg


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