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Offlinetregar
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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: breeg89]
    #26874833 - 08/11/20 10:59 AM (3 years, 5 months ago)

The Axe said:
Quote:

I've seen teks on the web for mushrooms that don't seem plausible at all, like lemon tek, but on the other hand I've seen other simple teks with lye or food grade lime seem like they do strip off part of a chain. I'm just wondering, other than subjectively, how to confirm whether there's an acetyl attached to the LSD-25 or whether something else is going on with acetyl during metabolism.



Well said The Axe, let's not forget the possibility that acetaldehyde could be adducting onto the NH group nitrogen of the ergoline indole of LSD "in vivo" in the liver to convert this to 1-acetaldehyde LSD. After all, the Aztecs and Mayans added the morning glory extract to wine/liquor, and the 1992 adducts paper is entitled:

"Tryptophan analogues form adducts by cooperative reaction with aldehydes and alcohols or with aldehydes alone: possible role in ethanol toxicity."

Note (2) Page 515 "Encyclopedia of Psychoactive Plants" Christian Ratsch: "The fresh or dried morning glory seeds normally are added to alcoholic drinks (sugarcane liquor; c. alcohol), tepache (maize beer, chicha), and balche' (Schultes 1941, 37)."

Here's an example: If you soak coca leaf tea bags in wine, and the wine drunk, the cocaine is converted into coca-ethylene in the liver...cocaethyelene is orally potent, it has a "higher like" rating than even cocaine when human tests were done in 1994. This was the basis behind the famous commerical "Vin Mariani wine" back in the 1860's popular with both Popes, Thomas Edison, and scores of other famous people. I don't see any cleavage taking place with this molecule but rather addition/transformation. This "in-vivo" liver transformation of the molecule was not even discovered till 1994 !

Perhaps this same "in vivo" transformation of LSD to 1-acetaldehyde LSD takes place in the liver via an enzymatic reaction that has not yet been discovered. I know the effects of LSD and 1-acetaldehyde LSD very well, as I have taken acid hundreds of times, and the 2 times I tried 1-acetaldehyde first at 300ug and 2nd time at 400ug were completely different, in fact I prefer the 1-acetaldehyde LSD by a long shot, it's the only way I will take acid for the rest of my life, I don't mind the extra expense of using 3 or 4 tabs at once for the conversion, it's cheap and plentiful in dreams. You have nothing to loose, my grocery store carried just one brand of Sherry wine, seen in the 1st pic of linked thread with 13 pics, "Taylor brand sherry" and the peppermint extract was right down a few isles.

Like I mentioned earlier, I've taken acid in all different amounts with 400g of fresh cactus tea (I grow lots of cactus under shade cloth) for over 15 years, and it always feels just like "acid + cactus", but when I took the 400ug of 1-acetaldehyde LSD with 400g of fresh cactus, for the 1st time in my life it felt like 700mg of mescaline, it was THE most profoundly infinitely beautiful and powerful trip of my entire life, I can't stop thinking about even 1 week later, big time life changing. I had complete control of my faculties, no tenseness or anxiety like with acid, no wandering thoughts, it was deep mentally, real gem, I would wave my hand and see not only tracers, but fractals inside the tracers, the beauty of the 2 women on screen from the new hulu movie "to the stars" was overwhelming, I was in heaven, the colors were out of this world impossible and breath-taking for hours on end...I thanked Heaven for this remarkable experience, the most profound of my life. Just my 2 cents.

Normalperson said:
Quote:

what's the worst that could happen? lose a couple of tabs and be stuck with a bottle of shitty wine? or maybe i would like the wine and become a wino? I'll try it out soon.



I laughed my ass off reading that.


Edited by tregar (08/13/20 08:04 PM)


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Offlinedownwardsfromzero
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Registered: 08/11/20
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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26878705 - 08/13/20 02:23 PM (3 years, 5 months ago)

Some of you may remember from my commentary at the Nexus my considerable scepticism that an aldehyde adduct on the nitrogen atom of a primary amide would form in any appreciable quantity simply by mixing the two ingredients in solution.

This reference:
Quote:

1. The condensation of aldehydes with amides
Rup Kishore Mehra, Kantilal C. Pandya; 1938; DOI 10.1007/BF03045405; Print ISSN 0370-0089



via here: Herbpedia
forces me to rethink my view in that respect.

That isn't particularly relevant to this thread, what with LSD-25 being a tertiary amide and all. Instead I respectfully will echo the point constructively made by breeg89 - the scientific value of anecdotal reports regarding qualitative differences in subjective experience resulting from a particular method of preparation serves only as a stimulus for investigating what is actually going on.

What if it were as simple as the fact that the LSD has gone into solution and is protected from oxidation by the sherry/mint tea components? And tregar, you've already noted the metabolic effect of menthol on the CYPxxx enzymes - what if that is what is making the trip smoother by preventing the formation of the more 'jangly' 13-OH-LSD, for example?

It would be most helpful to think through all the potential confounding possibilities and ways of controlling for them, because this effect seems to be pretty interesting. Preparing a sample of the putative 1-(1-hydroxy [or ethoxy]ethyl)LSD for analysis would be only one step for the scientific community. Working out what it does in the human body would be a whole other ball game.


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Writhing and groaning


Edited by downwardsfromzero (08/21/20 05:08 AM)


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OfflineSabnock
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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: downwardsfromzero]
    #26878795 - 08/13/20 03:20 PM (3 years, 5 months ago)

One must also take into consideration the influence of various compounds on the Psychedelic in question. It's not necessarily that a compound is turning into a different compound, it could just be that something that is being mixed with the compound is altering it's characteristics/flavor/feel, the quality/nature of the experience/effects. It's more easily done than one would think.


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Offlinetregar
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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: Sabnock]
    #26879016 - 08/13/20 06:08 PM (3 years, 5 months ago)

Downwardsfromzero and Sabnock so glad to see you both! What is gonna take for you guys to stop talking about it, and JUST TRY IT !!! So far, NO ONE has duplicated my experiment. Downwardsfromzero worked with me to draw up chemical diagrams at the Nexus in the fresh morning glory LSH thread before they suspended my account until the year 2294 for posting the current thread you are reading. :crazy2: Nexus. I just so happen to be a 220lb bodybuilder with 12% bodyfat, been lifting weights since age 22...and a bunch of pencil necks canned my post. They even deleted ALL THE PICS and study tables and graphs to all of my posts over there that belonged to me for the last 12 years, making all my posts useless.:mad2:

Dragonrider, we have proof a new product is being created...look at this from Vecktor (advanced chemist):
Quote:

Tregar you have probably rediscovered something that has long been a curiosity....the morning glory extract treated with acetaldehyde-methanol without the water showed a clear difference in the alkaloid profile, with a shift to several new non polar spots which couldn't be identified. IIRC Erhlichs was used to develop the plates so these were indole compounds.


So glad to hear Vecktor, thanks. It takes time for the new product to form when there is water involved--->the researchers achieved a 100% new product with or without the use of ethanol, it made no difference, you only need ph=4 acidified water and around a 0.1% acetaldehyde solution, with a 1.5 hour soak time with stirring. It just so happens that sherry wine is already at ph=4 just like the study calls for! Researchers said "the lower the PH, the faster the reaction."

Typerwritermonky said:
Quote:

Uhh tregar have you ever taken 1-acetylhyde-LSD on its own or only in combination with other substances?  This is interesting, but I still feel like 400ug of LSD-25 is a strong enough experience to question what in the world is going on.



Yes, I have taken this on it's own at 300ug, at 400ug and again tomorrow will be taking it at 400ug.

I have taken LSD hundreds of times over 15 years, and I am very familiar with acid vs this new alkaloid 1-acetaldehyde LSD, which I have found to be COMPLETELY different! You all have got to try this, it is one incredible substance at the 300 to 400ug level, not at all like LSD when taken at 300ug to 400ug.

I think this has to do with the possibility that 1-acetaldehyde LSD shifts the receptorome or radioligand binding of receptors "away from 5-ht2a" and towards the adrenal A2A, A2B, and A2C spectrum instead which is the dominance or habitat of mescaline & dmt & psilocin (see receptorome chart on post #1).

It feels more like mescaline or Ayahuasca at 400ug then 400ug of acid, way different, way more colorful, come up is relaxing like with cactus, profound visuals that look more like mescaline visuals than acid visuals, way more euphoric and beauty enhancing like with mescaline, not analytical at all like with LSD. Love, love, love this stuff, only way I will take acid for the rest of my life.

This has one more hydrogen molecule than ALD-52, so it's even different from ALD-52. This is one very beautiful substance.
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I have made 1-acetaldehyde LSD twice so far from 3 LSD blotters and then 4 LSD blotters the 2nd time, it is extraordinary, easy to do in one step and based on the 1992 adducts study with indole see below note (6).

This is absolutely no "pro-drug" it has effects all on it's own, COMPLETELY different from LSD from beginning to end of trip, see my 13 comments further below on how this is way different from LSD in profound ways, like an upgraded version of LSD.

I know that from now on this is the only way I will take 400ug of LSD for the rest of my life, as the "upgraded 1-acetaldehyde LSD cousin." My absolute favorite.

Don't bash me until you try this with 3 or 4 hits of acid yourself, it is based on pure science, and really works. With LSD, acetaldehyde will adduct onto the bottom indole NH group nitrogen of the LSD ergoline forming 1-acetaldehyde LSD, containing one more hydrogen at adduct than ALD-52.

The main recipe is based on the 1992 indole adducts study which creates a new 1-acetaldehyde (similar to ALD-52 but contains one more hydrogen molecule) alkaloid from LSD. The peppermint extract in the recipe contains menthol as the main ingredient which shuts off the cytochrome P450 enzyme inhibition in the liver, which is involved in the metabolism of exogenous chemicals. This has the potential effect in vivo of preventing the breakdown of 1-acetaldehyde LSD.

The same conversion described in this thread also works with the LSH (lysergic acid hydroxyethylamide) & penniclavine in morning glory seeds, converting them to 1-acetaldehyde LSH & 1-acetaldehyde penniclavine. As described below with supporting references in Notes, the ancient Aztec and Mayans and Priest at Eleusis for 2,000 years straight used this same conversion on LSH from the seeds, and LSH from the ground up claviceps paspali (ancient Greece) growing on the paspalum distichum grass adjacent to Eleusis to serve to hundreds of people at once, it has a low "freak out factor" (like with mescaline), so I can see why hundreds could take this at once. Fresh morning glory and fresh claviceps paspali ergot both contain the exact same alkaloid profile.

Researchers showed in 1961 that Claviceps paspali ergot produces high amounts of LSH in culture "Production of a new lysergic acid derivative (LSH or Lysergic acid hydroxyethylamide) by a strain of Claviceps paspali, Stevens & Hall".

See pics on how this also converts penniclavine (highest alkaloid in morning glory seeds) for example to the 1-(1-hydroxyethyl) penniclavine courtesy of downwardsfromzero (chemical genius) who drew up diagrams for all this stuff as he worked along with me, in 13 pics in the fresh morning glory LSH thread here at Shroomery.

Instructions:

Note (1): Make sure your sherry wine is cold before you use it, it contains 5 mg acetaldehyde per 15ml or 1/2 shot glass. Acetaldehyde boils off at 68 degrees F, or slightly below room temp, so keep 1/2 shot glass of it in fridge at all times until you consume.

Note (2): There is a less than ten dollar wine preservation canister available that will prevent oxidation of the wine, instead a bottle of sherry wine will last several months instead of just 7 days. This way the natural precious high levels of acetaldehyde in the sherry wine will not oxidize to acetic acid over time. The canister replaces the air that seeps into an open bottle with a balanced mixture of carbon dioxide, nitrogen and argon to keep wine fresh: just look up "private preserve wine preservation system", less than ten dollars. Seen it at amazon.

Note (3): Menthol is largest ingredient in peppermint extract and causes cytochrome P450 enzyme inhibition in the liver, which is involved in the metabolism of exogenous chemicals. This may have a potential effect in preventing the breakdown of 1-acetaldehyde LSD. Peppermint extract also contains 2mg water soluble acetaldehyde per 5 drops

1) Fill a shot glass up 1/2 way with dry sherry wine. Sherry wine is already at ph=4 which is what study calls for, and contains the acetaldehyde (5mg avg. per 15ml) we need like the study.

2) Drop 3 hits of 100ug acid into shot glass.

3) Put a foil cover on shot glass and let sit in fridge.

4) 1 hour later add 5 drops of Adam's peppermint extract.

5) Swirl the shot glass once per hour, the researchers used a stir mantel in the fridge, and achieved 100% new product creation in 1.5 hour, but since we are not using a stir mantle, swirl once per hour.

6) After 3 hours sitting in fridge, consume, sit back & enjoy the brand new experience of 1-acetaldehyde LSD, or what is similar to ALD-52 with one extra hydrogen at the bottom indole NH group.
--------------------------------------------------------------------
LSA (C16 H17 N3 O) + acetaldehyde (C2 H4 O) at bottom indole NH group = 1-acetaldehyde LSA
LSH (C18 H21 N3 O) + acetaldehyde (C2 H4 O) at bottom indole NH group = 1-acetaldehyde LSH
LSD (C20 H25 N3 O) + acetal (C2 H3 O) at bottom indole NH group = 1-acetal LSD (C22 H27 N3 O2) or ALD-52
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Note (6) 1992 adducts study: hxxps://www.ncbi.nlm.nih.gov/pmc/articles/PMC49935/ Page 8441 "Reaction of Indole with Acetaldehyde: A 0.2% solution of indole in equal amounts of water, ethanol, and acetaldehyde formed a product with 60% yield after 1 hour of reaction at ambient temperature. Omitting the ethanol (50% acetaldehyde in water mixture) had no effect. Decreasing the concentration of acetaldehyde to 0.1% increased the reaction rate and percent yield of product." See pic of the researchers's indole + acetaldehyde adduct product formed at bottom of this post ---> ie before (page 8439) and after (page 8441).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC49935/

The researchers achieved a 100% new product with or without the use of ethanol, it made no difference, you only need ph=4 acidified water and around a 0.1% acetaldehyde solution, with a 1.5 hour soak time with stirring.

Note (15) Breakdown of water soluble acetaldehyde & isovaleraldehyde (and their corresponding acids) in peppermint extract: 1mg standard is equivalent to .001ml, 5 drops used in recipe = .25ml, .25ml = 250mg identified compounds, alcohol percent of peppermint extract = 91% alcohol so then 250mg x 0.9% = 23mg leftover of compounds, assuming 9% of this is the acetaldehyde/isovaleraldehyde & their corresponding acids, [see paper "Chemical Composition and Biological Activities of Mentha Species by Brahmi"] then approximately 2mg exists in 5 drops.
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In conclusion, my personal observations, as I have taken acid hundreds of times in the past not only by itself, but in combination with 400g of fresh boiled cactus tea (I grow my own cactus under shade cloth) over 200 times in over 15 years, I keep a trip diary.

I also grow around 30 ipomoea tricolor heavenly blue morning glory plants, 15 to each 17" wide x 15" tall planter with 7 foot tall round welded wire fence (from garden store) in each, equivalent growing area of a 7 foot tall x 4 foot wide fence, grown in 3/4 miracle grow + 1/4 cow manure compost, produces extremely potent LSH & penniclavine containing seeds, that I pick when seeds are dark and hard and immediately vacuum pack and store in freezer to keep their high potency indefinitely. Each planter produces 3,000 seeds (5 seeds per pod), 6000 seeds total divided by 400 seeds per trip = 15 high potency trips. Even just small amounts of these seeds also potentiate normal LSD in combination, producing outstanding visions and transcendence beyond just normal LSD.

1) You know how acid has that sudden drop off then you are back to sobriety? Instead, this lasts longer than acid and has a warm gentle transition back over a longer period.

2) 1-acetaldehyde LSD is way more colorful than acid, similar to mescaline.

3) 1-acetaldehyde LSD does not have the "visual choppiness" of acid, but is flowing in the visuals.

4) LSD produces tracers with multiples of shadows of the hand, this produces not only tracers, but colored fractals and mosaics inside the tracers.

5) LSD produces "colored specs that flow in front of everything", this produces instead "fine colored rainbow reflections" that surround everything.

6) Music sounds good on acid, but music sounds great on this, like a whole nother world, similar to mescaline.

7) With 1-acetaldehyde LSD, everything was indeed alive and magical. Patterns were forming everywhere, the shifting of textures is magical. I could lose myself so easily as the visuals seemed to drag my focus in without any effort. As a result, ego death was basically spontaneous. Taking this 2 times already, made it feel like the first time I've ever tripped. My 2nd trip with 400ug 1-acetaldehyde LSD in combination with 400g fresh cactus tea was the most infinitely beautiful & powerful trip I have ever experienced in my life.

8] Sometimes LSD causes my mind to wander uncontrollably unless I take my own drive to focus, but with 1-acetaldehyde LSD there is no wandering thoughts, no tenseness or anxiety like with acid, this is deep mentally, a real gem, pure psychedelic bliss.

9) 400ug of 1-aceteldehyde LSD makes 400g of fresh boiled cactus pieces (no core, approximately 400mg mescaline) feel instead like 700mg of mescaline. I think this has to do with the possibility that 1-acetaldehyde LSD shifts the receptorome or radioligand binding of receptors "away from 5-ht2a" and towards the adrenal A2A, A2B, and A2C spectrum instead which is the dominance or habitat of mescaline & dmt & psilocin (see color chart post #1 of old long thread).

10) You can take this more often as it does not have the "extreme tolerance" of normal LSD which mainly works thru the 5-ht2a receptor (see color chart post #1), just like with cactus which you can take more often.

11) It is not a sacrilege to convert LSD to 1-acetaldehyde LSD cause Albert Hofmann also discovered ALD-52 at Sandoz labs. This is different from ALD-52 cause it has one extra hydrogen on the acetaldehyde adduct at the bottom indole NH group nitrogen. The table from Sandoz suggested that ALD-52 might actually have advantages over LSD, reducing any side effects but achieving a stronger trip. Measurements of brain waves while people were taking the two drugs showed that while LSD produced brain waves associated with intense concentration and anxiety, ALD-52 produced brain waves showing a more relaxed mental state. It also has "twice the anti-serotonin or serotonin blocking power" of normal LSD.

12) Before falling to sleep, I saw closed eye colored visions of architecture and gardens like those in Versailles, France.

13) LSD is more "analytical" and not as aesthetic, this feels more natural and is extremely aesthetic (beauty enhancing) like with mescaline.
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Final notes when working with mg seeds instead of LSD:

Penniclavine is found in extremely high amounts in the mg seeds & in claviceps paspali infected wild grass Paspalum distichum L, with the labile LSH a close second in both of them and binds to 5-ht1a, 5-ht2a, 5-ht6, 5-ht7, adrenal A2A, A2C, A2D, and most of the dopamine receptors.

We don't have radioligand binding data for LSH, we only know it is similar to LAE-32 in TIHKAL, in which human experiments were done, at 1.5mg it was stimulating & "LSD like".

LSD only binds to A2A in comparison (when in comes to adrenal receptors, note 11). When Yui & Takeo injected penniclavine & agroclavine into lab animals in 1958 they noticed the animals became stimulated like with LSD. Penniclavine is a metabolite of agroclavine. Glasser in 1961 noticed animals also became stimulated when injected with LSH. Dr. Glasser said some of the mice even stood on their hine legs and pressed on the noses of the mice in front of them, very peculiar.

Animal tests all point to LSH being an active psychedelic and it is indeed the closest thing to LSD found in nature, far closer than d-ergine (LSA). Owsley claims Hoffman himself told him that LAOH is very LSD-like. I totally agree.

As everyone knows, 2 drugs combined is more potent than just one.

A 2014 forensics paper from Paulke found no LSH in HBWR seeds, but only found LSA & iso-LSA (83-84%) & ergometrine (10-17%) & rest: lysergol, elymoclavine & chanoclavine. We know that MG has centuries of Shamanic use, while HBWR has no history of Shamanic use. HBWR only has history of medicinal use.

Sandgrease: "HBWR has more of a sedative effect compared to MG."

Nogal: "HBWR is more body related while MG seeds have effects more similar to LSD."
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I did not discover this conversion, it was given to me by an ancient spiritually prominent Shaman in a vision, true story, see here:

Discovered 1992 adducts study the same week after receiving a 20 minute visit or "schooling" from an ancient powerful and spiritually prominent Aztec Shaman who appeared out of the shadows on a wall cast by a Christmas tree, this after girl and I both took 10 hits each of 15 year old decomposed acid given to me by a dear friend, true story. The acid had a sick feeling for the 1st two hours, but then it worked and skyrocketed us to higher divine plane.

The Shaman sat on a throne made of spirit animals (birds, otters, Jaguars, macaws, toucans) that morphed into other spiritual animals continuously. The Shaman stared intently into my eyes as if downloading information to me. What's even more amazing, is that the girl who was with me also saw the EXACT same vision on the wall.

The Shaman wore a huge beautiful headdress made of feathers, to the left and right of him stood female centaurs, half naked female above, half animal below. He showed me the rise and fall of several civilizations throughout time. I saw the great pyramid of the Aztec empire in the distance. The animated vision was beyond 4k, and highly detailed.

Behind the female centaurs were snakevines growing out of the ground. Before the Shaman left, he motioned to me with his eyes to look out the window in the living room to the patio, where I had an empty garden plot, he was trying to tell me to plant entheogenic plants. His point in showing me the rise and fall of the different civilizations was I believe he was trying to tell me "that if humanity is survive, the only hope is a Spiritual solution."

Don't forget that to the Aztecs, the morning glory plant was more important to them then their other 2 classical plants, peyote and mushrooms. Two sources given for this comment below.

Note (2) Page 515 "Encyclopedia of Psychoactive Plants" Christian Ratsch: "The fresh or dried morning glory seeds normally are added to alcoholic drinks (sugarcane liquor; c. alcohol), tepache (maize beer, chicha), and balche' (Schultes 1941, 37)."

Note (4) Psychotomimetics of the Convolvulaceae pg 93: "This particular plant seems to have been more important to the Aztecs in divinity then Peyotl or Teonanacatl, two of their other classical sacred plants."

Note (5) Jonathan Ott "Pharmacotheon": "Ololiuhqui was far more prominent as an entheogen here in Mesoamerica than those mushrooms; the mushrooms are mentioned only here and there by a few competent chroniclers; yet almost an entire book was devoted to denouncing mainly the ololiuhqui idolatry. The annals of the Inquisition contain many times more autos de fe for ololiuhqui than for mushrooms."

Note (22) The sources were clear that the kykeon's other ingredient, mint (menthe pulegium) was fresh mint. Mint appears to have played a symbolic role in Eleusinian myth; being Hades' concubine, Mint was "dismembered by the jealous wife Persephone." See Wasson, "The Road to Eleusis", 111.

In Ipomoea Tricolor vine: from Tryptophan-->chanoclavine-->agroclavine-->elymoclavine-->lysergic acid-->ergometrine-->LSH, which then decomposes over time into LSA.

2016 Polish morning glory study found 3x higher amounts of LSH in MG seeds direct from grower/producer vs retail:
Quote:

fresh black seeds from vine: likely 5.00 LSH to 5.00 penniclavine ratio
seeds direct from growers: 1.71 LSH to 5.08 penniclavine ratio
seeds off retail racks: 0.54 LSH to 4.75 penniclavine ratio



Vacuum pack & freeze freshly picked seeds to preserve potency indefinitely.

LSH (lysergic acid hydroxyethylamide) decomposes in neutral water solutions, and quickly in alkaline solutions, and also if heated, but it is quite stable in acidic environments (just like the solution recipe I give). Traditionally (e.g. as reported from Wasson) they only soaked the mushed seeds briefly in water, then strained and immediately drank. Even Hermes and Nogal (both extracted 400 to 500 seeds into cold acidic water using a squirt of lemon juice) both reported EXTREMELY VISUAL MG trip reports:

(1) Hermes (the Lycaeum):
Quote:

Cold water extract with squirt of lemon juice: Saw strong 4D lattice-like open eye visuals and warping and melting of furniture with only 400 seeds. There are around 32 to 36 seeds to a gram. I see amazing three and seemingly four-dimensional shapes morphing and bifurcating. Often I get religious and esoteric themed visuals, like fractal cherub wings and winged eyes like those in some of Alex Grey's work. Eyes are all over everything. I see pyramids and sphinxes and Gigeresque biomechanical forms. I see amazing geometric lattice structures. I watch mathematical space-filling algorithms doing their thing, all of this with nothing more than 500 seeds.



(2) Nogal (the Nook):
Quote:

Yes I know of someone who tried the CWE method with the Heavenly Blue variety, except with the substitution of a coffee grinder in place of a stone metate (I think that's what is called but I could be wrong), and a squirt of lemon in the water, with around 400-500 seeds. Closed and open eyed visuals were extremely breath taking. Some of the most prominent visions were of Aztec/Mayan glyphic patterns, a menacing and demonic technicolor nymph made of light who tried to seduce the viewer, and this bizare trail of energy spheres which each contained a different stylized animal form (again definately of Aztec/Mayan origin).



(3) Erowid report:
Quote:

400 older dried seeds is similar to a little less than one hit LSD. 400 fresh off vine is like about 2 or three hits.



Myself: 500ml cold spring water acidified to Ph=4 with DL tartaric acid extract on 400 fresh off the vine dark hard heavenly blue morning glory seeds that I grew in 3/4 miracle grow + 1/4 cow manure compost, fed 1 tablespoon miracle grow crystals dissolved into 1 gallon watering can w/spout once per month only, 22 years ago, added 1 shot of sherry & 5 drops peppermint extract, let sit in fridge 3 hours with swirling once per hour:
Quote:

Saw geometric patterns on the surface of everything, with closed eyes, colored vectors spun 360 degrees while traveling from left to right across visual plane. Sounds were not only amplified & music heavenly but audio hallucinations were produced, heavy euphoria component & very strong appreciation for beauty. Remember watching Scarlett Johansson interview on a small television and melting into the seat from her beauty amidst all the breath taking geometrics. Tripped hard as hell.



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I am not a shaman, but I have been thru alot of the stuff Shaman's have gone thru, I have lost both my twin girls at birth, so I have no children, my beloved pet Shitzu died at only age 4 from continuous bladder stones for 6 months, he was unable to pee so many times, we had to rush him to vet, where he was put down. He visited both of us in a dream 2 days later to tell us he was alright in Heaven with a big smile on his face.

I have nearly died several times, once I was hit head on by a truck when driver ran a yield sign, I barely survived with numerous injuries.

I once took alot of acacia bark with Ayahuasca instead of the normal hawaiian psychotria I use, and went into a serious serotonin syndrome shock, for 1.5 hours I sweated my ass off sitting in the bathtub, I told my wife goodbye while my dog watched in a sad state..by some miracle I pulled out of it, I believe it was the high levels of maoi's in the acacia that interacted with the rima's in the Ayahuasca, bad combination. My forehead was pouring sweat for 1.5 hours, I was in severe shock and trembling, and knew I was gonna die.

Lost everything in a 100 year severe flood, my home and all my belongings, I had just gotten married and all the newlywed gifts perished...right after that I moved to an apartment complex, and 5 months later all my belongings again burnt to the ground after a dude had threw a lit blunt into the apartment complex after his girlfriend dumped him.

Had it not been for the policeman banging on the door of the apartment, we would have surely burned in the flames, as we were on the 3rd floor & asleep as I worked 2nd shift at the time. We ran down the steps in only our bare feet and suffered smoke inhalation.

Have been thru some %!%%, similar to a Shaman, who lives on the outskirts of society. Lifting weights, walking in nature with my dog, going to the waterpark with a season pass every summer, and reading the bible is all that keeps me sane some days.
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Stay true to yourself, Peace, Love & Music.

https://www.friskyradio.com/


Edited by tregar (09/04/20 04:42 AM)


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Offlinetregar
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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26879045 - 08/13/20 06:27 PM (3 years, 5 months ago)

I will leave you with this...by the way I will be taking 1-acetaldehyde LSD again at 400ug this Friday for the 3rd time, this time in combination with 400g of fresh boiled cactus tea, as it's been 2 weeks.

This conversion also works on morning glory and HBWR seed extracts as explained earlier in this thread, the Mayans and Aztecs added the fresh or dried morning glory seed extracts to a drink containing wine or liquor, see notes section of this thread.

Downwardsfromzero:
Quote:

As I've mentioned, my most successful plant-derived lysergamide experience - in dreams, of course - albeit with HBWR, coincided with intake of a fairly large quantity of brandy which, in all likelihood, produced a significant level of acetaldehyde within my body, exposing the plant lysergamides to the correct conditions (as reported in the Austin & Fraenkel-Conrat PNAS paper) within my stomach for the putative 1-(1-hydroxyethyl) or, rather, it seems, the 1-(1-ethoxyethyl) derivative to be formed. In this case, the effects were clearly stimulating, unlike the sedative effects usually reported for HBWR. I see that brandy weighs in fairly well on the acetaldehyde content scale as well.

The neon-electric zingyness of LSD was all but absent, although there was a fractal overlay with eyes open. The overall feel was more earthy and organic. A wise, stern-but-kind voice within gave me most useful advice for several hours. This also contrasted with the 8 hours solid 'LMAO' that LSD so often provides. The divinatory use of this type of material makes absolute sense. I count this among the more significant entheogenic experiences of my life.



Norman at mycotopia also mentioned his powerful and very enjoyable experience when he extracted HBWR with wine and consumed. He said it was better then any other kind of extraction method by far.

And don't forget the comments by 69ron and Kash further up in this thread who combined the seed extracts with peppermint extract which contains 2mg acetaldehyde per 5 drops, they said the experiences turned into stimulating instead of sedating experiences, and were profoundly visual compared to normal extracts.

Krystle Cole from the book "Lysergic":
Quote:

"Isn't Ergot what Socrates used to take at Eleusis?" I thought it was kind of cool to be taking something that the founders of our democracy used to take, but that our current democracy has made illegal.

LSD chemist Todd Skinner replied "Yes, except for he did a water infusion of the ergot, instead of alcohol." Todd had prepared 6 jugs of ergot wine and stored them for many years.

Krystle Cole's "ergot wine" experience (several pages long) in the book "Lysergic", reported that she saw constantly rotating holographic Sanskrit or Arabic & Zodiac symbols, floating in a circle around Todd's head.



It was so powerful that it was the only time Krystle said Todd would say a Prayer before ingesting, he never said a Prayer with any other substance.

How is this for alchemy? The Greek Priest & ancient Aztec & Mayans were not the only ones to transform their brews. Dr. Shulgin in an issue of the "Entheogen Review" in the "Questions to Dr. Shulgin section" describes how harmaline gains 2 hydrogen atoms from Vitamin C doner (same way Santo Daime brew their Ayahuasca for long periods with added vitamin C) transforming all the sleepy dreamy harmaline in their brews into the stimulating, euphoric & colorfully visual anti-serotonin alkaloid tetrahydroharmine, via an Alchemy process, Note (27). All of their brews shown in table 1 had zero mg harmaline left.

In a similar way LSH & LSA & LSD in the thread's recipe brew are transforming to their stimulating doubly anti-serotonin, highly visual + audial, very euphoric + more colorful, zero anxiety, tenseness & wandering thoughts, more aesthetic beauty enhancing cousins 1-acetaldehyde LSH & 1-acetaldehyde LSA & 1-acetaldehyde LSD via the donation of acetaldehyde under proper acidic conditions.

Remember ALD-52 was shown by Sandoz labs to have "double the anti-serotonin power of LSD" and the more serotonin blocking, the more stimulating. The liver-produced Coca-ethylene from cocaine in coca leaf tea bags (5mg per tea bag) soaked in wine (and the wine drunk) is another example of a powerful anti-serotonin alkaloid which is highly stimulating. Cocaethylene has a higher affinity for the dopamine transporter than does cocaine. Cocaethylene produces euphoria and has a longer duration of action than cocaine.

Note (27) Callaway, James C. (June 2005). "Various alkaloid profiles in decoctions of Banisteriopsis caapi." See wikipedia page on tetrahydroharmine in references at bottom, Page 154: "The average ratio of THH to harmine in the Santo Daime brews was consistently near 1:1, from all sources (Table 2), while the ratio was closer to 1:5 in a large survey of the source plant material (B. caapi)." Page 154 describes the process of conversion under acidic conditions with chemical diagrams.

Here are just a few of the other topics I have posted about:

1) How to convert the research chemical 4-aco-dmt (which I don't like) to 4-ho-dmt (actual psilocin)

2) Was the first to show how to complex the nbome's with the super cheap HPBCD (hydroxy propyl beta cyclodextrin) to create a bioavailable form of the drug that could be absorbed readily under tongue. HPBCD is the basis behind the highly popular "Febreze" to trap odors and dispose of them as well. Nearly all the suppliers of nbome's in the world took my idea and marketed them as such. I regret that decision as I hate the man-made drug 25i-nbome. I flushed all mine down the toilet.

3) How to create a 100% nausea free Ayahuasca brew to the stomach & intestines using cotton ball in a funnel filtering. The cotton ball and funnel are the best invention since the toothbrush. Yes, Coffee filters are useless as they allow nothing through.

What I'm trying to say is that I would not post about this 1-acetaldehyde LSD if it did not work. Why would I invest so much time and effort to convey this discovery if it had no merit?

Vecktor:
Quote:

Tregar you have probably rediscovered something that has long been a curiosity....the morning glory extract treated with acetaldehyde-methanol without the water showed a clear difference in the alkaloid profile, with a shift to several new non polar spots which couldn't be identified. IIRC Erhlichs was used to develop the plates so these were indole compounds.




Edited by tregar (08/13/20 06:30 PM)


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InvisibleInfiniteDreams
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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26879203 - 08/13/20 08:23 PM (3 years, 5 months ago)

:eek:


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Invisiblebreeg89
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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: Sabnock] * 1
    #26879292 - 08/13/20 09:52 PM (3 years, 5 months ago)

Quote:

Sabnock said:
One must also take into consideration the influence of various compounds on the Psychedelic in question. It's not necessarily that a compound is turning into a different compound, it could just be that something that is being mixed with the compound is altering it's characteristics/flavor/feel, the quality/nature of the experience/effects. It's more easily done than one would think.




Very true. It could also be purely placebo -- it could be the ritual of the preparation itself that's altering the experience.  Without analytical data and blinded dosing, it's all just speculation. The blinded dosing is critical because even if analytical data confirm the formation of the indole N-adduct, chemistry principles suggest the product is a prodrug, so without a blinded study, you can't rule out the possibility that perceived differences in the effects are entirely subjective.


Edited by breeg89 (08/13/20 09:59 PM)


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: breeg89]
    #26881399 - 08/15/20 10:24 AM (3 years, 5 months ago)

namaste said:
Quote:

Might have a go this weekend, all depends on my fragile mental health.  Been eating doses 25+ years.  Lots of work drama, we shall see.



You will find that your mental health will thank you after trying this at 300ug, just yesterday (Friday night) again took 400ug of the 1-actealdehyde LSD with 400g of fresh boiled cactus tea, once again, was blown away by the power of this.

Namaste, thanks for trying this out...you will find this is easy on your mental health...There is Zero anxiety, zero tenseness, zero wandering thoughts, no "neural overload" feeling like with normal LSD...deep mental space, pure psychedelic bliss. Replacing the "electricity" of LSD with calm, profound beauty enhancement to the nth degree and visuals way beyond normal LSD.

The comeup is smooth and relaxing like with cactus, no sudden drop off like with acid as it lasts much longer than acid with a warm gentle transition back to reality over a long period of time. Like a long warm hug and embrace.

With closed eyes, high speed movies played in color in the visual plain, flowers, animals, beautiful people, vast meadows and gardens, grand architecture including palaces and interior decorations within them. I climbed the steps of one of these palaces surrounded by art carvings of animals to the left and right of all the steps leading up to the entrance. Mind blowing visions.

With open eyes, colors were once again out of this world and impossible for hours on end, the beauty was infinite as patterns formed everywhere and inside the tracers when I moved my hand I once again saw colored fractals inside them, extremely powerful visuals and transcendence. I never see fractals inside tracers on normal LSD, just shadows of the hand.

This is the only way I will take acid from now on till I die. Extremely beautiful experience with none of the side effects of normal acid.


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26881508 - 08/15/20 11:36 AM (3 years, 5 months ago)

namaste said:
Quote:

Might have a go this weekend, all depends on my fragile mental health.  Been eating doses 25+ years.  Lots of work drama, we shall see.



You will find that your mental health will thank you after trying this at 300ug, just yesterday (Friday night) again took 400ug of the 1-actealdehyde LSD with 400g of fresh boiled cactus tea, once again, was blown away by the power of this.

Namaste, thanks for trying this out...you will find this is easy on your mental health...There is Zero anxiety, zero tenseness, zero wandering thoughts, no "neural overload" feeling like with normal LSD...deep mental space, pure psychedelic bliss. Replacing the "electricity" of LSD with calm, profound beauty enhancement to the nth degree and visuals way beyond normal LSD.

The comeup is smooth and relaxing like with cactus, no sudden drop off like with acid as it lasts much longer than acid with a warm gentle transition back to reality over a long period of time. Like a long warm hug and embrace.

With closed eyes, high speed movies played in color in the visual plain, flowers, animals, beautiful people, vast meadows and gardens, grand architecture including palaces and interior decorations within them. I climbed the steps of one of these palaces surrounded by art carvings of animals to the left and right of all the steps leading up to the entrance. Mind blowing visions.

With open eyes, colors were once again out of this world and impossible for hours on end, the beauty was infinite as patterns formed everywhere and inside the tracers when I moved my hand I once again saw colored fractals inside them, extremely powerful visuals and transcendence. I never see fractals inside tracers on normal LSD, just shadows of the hand.

This is the only way I will take acid from now on till I die. Extremely beautiful experience with none of the side effects of normal acid.

Hey Traeger
Quote:

Got a good mindset going.  300 sounds reasonable, 400 excessive as I usually go with 100-200.  Just picked up a bottle of cooking Sherry and a bottle of peppermint extract.  Blast off at 7pm central time. These are the Ric and Morty blotters, pretty confident that they're at least 100mcg.


Yes, Namaste! Thanks for trying this...300ug is PLENTY! My calculations are off, 400ug is not necessary, this I discovered after my 3rd experiment with this. Mine are extremely pure 100ug, they were run thru the purification chromatography column twice according to where they came from.


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: downwardsfromzero]
    #26882779 - 08/16/20 05:14 AM (3 years, 5 months ago)

Quote:

What is gonna take for you guys to stop talking about it, and JUST TRY IT !!!


Thanks to you, I've located my I tricolor seeds and they're sprouting as best they can (a bit old). Fingers crossed I'll be testing the Eleusinian formula later this year.

As for trying this specific version relevant to this thread - obtaining actual LSD is out of the question for me at the moment although I do have a small amount of a closely related 1-acylated ergoloid that I'm willing to put through the process as some kind of active control.

That boils down to a question of time scheduling.

I wonder how this method might impact the effects of other things - that is to say, what would happen if DMT or psilocin was dissolved in peppermint sherry (and how about Crème de Menthe?), or even a non-indole such as mescaline?

Gathering of experiential data is a bit of a minefield - some minds are more forgiving of persistent alteration than others - and appropriate tolerance and integration breaks, out of necessity, have their place.

I'm eager to contribute my own experiential data to this question but the actual process is heavily constrained by logistical factors. In the meantime, my ongoing output of questions and nuances is done in the hope of inspiring directed experimentation in those with the opportunity to do so.


--------------------
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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: downwardsfromzero]
    #26882863 - 08/16/20 07:04 AM (3 years, 5 months ago)

namaste said:
Quote:

The Love is soaking, got a little zesty, overswirled and spilt a tiny bit.  Have you considered sending to EC for a MC/GS?  I think it's the only way to actually prove the molecular structure has been altered.


Yes, be careful, just swirl lightly, and put a saran wrap or foil on cover of shot glass to prevent spill over.

We have proof already that the conversion is happening with morning glory seed extract, see here:

Vecktor (advanced chemist):
Quote:

Tregar you have probably rediscovered something that has long been a curiosity....the morning glory extract treated with acetaldehyde-methanol without the water showed a clear difference in the alkaloid profile, with a shift to several new non polar spots which couldn't be identified. IIRC Erhlichs was used to develop the plates so these were indole compounds.


So glad to hear Vecktor, thanks. It takes time for the new product to form when there is water involved--->the researchers achieved a 100% new product with or without the use of ethanol, it made no difference, you only need ph=4 acidified water and around a 0.1% acetaldehyde solution, with a 1.5 hour soak time with stirring. It just so happens that sherry wine is already at ph=4 just like the study calls for. Researchers said "the lower the PH, the faster the reaction."

Breeg89 said:
Quote:

the finding that ALD-52, 1P-LSD, and 1B-LSD show 5-10-fold reduced 5-HT2A binding affinity compared to LSD in vitro.

the finding that giving rats ALD-52 or 1P-LSD produced high concentrations of LSD in the blood.

the finding that giving rats ALD-52, 1P-LSD, or 1B-LSD initiated the characteristic psychedelic head-twitch response (despite dramatically reduced 5-HT2A binding affinity in vitro).



1. Like I said, 1-acetaldehyde LSD does not work thru the 5-ht2a receptor, but rather shifts the receptorome or radio ligand binding "away from 5-ht2a" and towards the adrenal A2A, A2B & A2C receptor binding which is the dominace or habitat of mescaline, dmt, and psilocin, see color chart on page 1. That's why 1-acetaldehyde LSD is more colorful, zero anxiety & tenseness, more visual, amazing mental headspace.

2. This is not an experiment done with rats, this is a human experiment. We are not giving a rat a shot of sherry wine with LSD dissolved with 5 drops of peppermint extract, did you forget to read my post earlier which shows that menthol is the highest ingredient in peppermint extract, which shuts down the cytochrome P450 enzyme in the liver which is involved in the metabolism of external chemicals? This has the potential effect of preventing the breakdown of 1-acetaldehyde LSD.

3. This works, I have taken acid HUNDREDS of times in 15 years, there is no mistaking 1-acetaldehyde LSD with acid, completely different, see my 13 comments on how this is different from LSD further up.

downwardsfromzero said:
Quote:

Thanks to you, I've located my I tricolor seeds and they're sprouting as best they can (a bit old). Fingers crossed I'll be testing the Eleusinian formula later this year.

As for trying this specific version relevant to this thread - obtaining actual LSD is out of the question for me at the moment although I do have a small amount of a closely related 1-acylated ergoloid that I'm willing to put through the process as some kind of active control.

That boils down to a question of time scheduling.

I wonder how this method might impact the effects of other things - that is to say, what would happen if DMT or psilocin was dissolved in peppermint sherry (and how about Crème de Menthe?), or even a non-indole such as mescaline?

Gathering of experiential data is a bit of a minefield - some minds are more forgiving of persistent alteration than others - and appropriate tolerance and integration breaks, out of necessity, have their place.

I'm eager to contribute my own experiential data to this question but the actual process is heavily constrained by logistical factors. In the meantime, my ongoing output of questions and nuances is done in the hope of inspiring directed experimentation in those with the opportunity to do so.



Thanks downwardsfromzero! I'm so glad to see you back with another post!

Typewritermonkey said:
Quote:

Tregar is it the same potency as LSD, or less potent?  Because 300-400ug of LSD-25 to me is a very huge dosage.



See below...

Thanks for trying this in the future Typewritermonky! Here is another trip report with ALD-52 vs LSD (not from me) which will help others understand the differences, and why a higher dosage is necessary:

Quote:

hxxps://www.reddit.com/r/LSD/comments/4yn8ou/highly_underestimated_ald52/

"Yes, I realize it's not technically LSD but really, it might as well be. I took 300ug thinking it would be mild if anything. Granted it wasn't as intense mentally as LSD can sometimes be, but conceptually and aesthetically it is beautiful beyond anything I ever anticipated. I feel perfect. At one. Better than I've felt in so long. I thought I could never trip again on anything but this is honestly paradigm changing for me. ALD-52 should be considered just as powerful as LSD-25 although it's a lot more relaxed and somewhat forgiving. As it is probably apparent I'm still very deep into this experience and I hope this to be an open discussion to anyone who would like to be involved.

My god, I just went through multiple ego death experiences beyond anything I've ever experienced from LSD before. There are no words. I mean there are plenty of "words" but none of them mean a single thing compared to any of THAT. Dear GOD. I never expected anything like this, but I sure as hell needed it. Even if I'm the only one here to express it to, as that's realistically the truth of nature anyhow. However, anyone who felt compelled to actually read through all this insanity, I just want you to know you're beautiful and you are everything. All things are right and they always will be.

Anyway, as far as the ALD-52, I took 300ug as I said. It was amazing and stronger than I expected, however I don't think 100ug would be very eventful to be perfectly honest. If you're concerned about it being too strong 200 might be worth it but 300 was really a great amount if you ask me. Even if you haven't taken any lysergamides before ALD-52 is rather calm compared to LSD or even mushrooms for the most part. Visually though, at least for me, it was absolutely breathtaking. Colors and textures were shifting like crazy.

Everything was alive and magical. Patterns were forming everywhere. I could lose myself so easily as the visuals seemed to drag my focus in without any effort. As a result, ego death was basically automatic and I reached that point multiple times. The first time I ever experienced ego death on LSD it left me with this beautiful feeling, like a deep inner glow that lasted for months afterwards. It eventually faded and I hadn't felt anything quite like it in years, but ALD-52 brought it back, and I feel like I've awakened from a spiritual coma.

Another thing is LSD sometimes causes my mind to wander uncontrollably unless I take my own initiative to focus, especially during the come up which can also sometimes fill me with restless confusion. Once I peak everything usually evens out, but ALD-52 put me in a state of perfect clarity from beginning to end. The come up was so smooth and comfortable.

I didn't notice the come down because I actually went to sleep when I felt like it was time to do so, which was an interesting surprise. Every time I've taken LSD I've had to let it run its entire course before even attempting to sleep. Often I would have to stay up for the entire day after which is obviously physically and mentally exhausting. But once I felt like the ALD-52 had made its point I went to sleep just like any other day, and woke up the next morning fully rested and mentally clear.

Overall, it felt very natural and I never had a single moment of uncomfortability or confusion. Just pure psychedelic bliss. I mean, I've had some amazing and extremely important experiences on LSD but honestly after the other night, think I prefer ALD-52. It felt like tripping for the first time again.




A few more comments from reddit, there are actual "fan clubs" devoted to ALD-52 over there, but keep in mind 1-acetaldehyde LSD has one more hydrogen atom on adduct than ALD-52, so it is even different from that:

Quote:


It's practically extinct! ALD52 is my favorite thing over even LSD and the site I used to get it from shut down.
-----------------------
ALD-52 is probably most similar to LSD relative to the other analogues (of which I have only tried ALD-52). The headspace is markedly psychedelic, it lasts 12 hours and the visuals are prominent enough. They seemed to take on a more flowing characteristic than LSD, to where I'd see objects form within the patterns.

I find it has a more mellow vibe than LSD, I'm more content to sit back and relax whereas 1p is supposedly closer to the electricity of LSD.

For what it's worth, I found the come down of ALD-52 to be better than LSD... it just felt more refreshing, like a warm hug and it tapers off gently whereas LSD is more of a sudden drop off into sobriety, but the actual peak of LSD feels more... alive to me. like my consciousness is oscillating at a super high vibration.
-----------------------
I find it's also less prone to creating anxiety. Becuase of this, I feel like I can take much higher doses and go much deeper. I took 5 tabs and experienced absolutely no anxiety at all. I don't think I would have been able to to do the same with LSD-25.
-------------------------
Hmmm. I seem to get much more euphoria from ALD over LSD or 1p. But yes, the anxiety levels are consistently low with this chemical. ALD is an absolute gem.
-------------------------
Agree. I feel like it's a subtle power, not as forceful as 1p. But there's genuine depth to it.
-------------------------
I'll be the first to admit it may be placebo, but I also favor ALD-52 for this reason.
-------------------------
I dosed ALD52 like 100+ times throughout the last 4 or 5 years, in doses between 25ug and 350ug.

While ALD52 is very similar to LSD25, I think I can still see a slight difference. To me the visuals are different, especially the tracers. I can clearly see a difference there.

With 200ug+ of ALD52, when I move my hand it shows some very colorfull spirals and fractals in the tracer /smearing.

While with LSD25 it is just a mirroring effect that shows several of my hands. Not nearly as colorfull, just a non colored shadow (or several) of the real hand.

With ALD52 it's much more colorfull and intense, like painting the air with rainbow colors.

100ug or even 150ug don't really show a difference at all to LSD25, but with 300ug and above (my highest dose was 350ug) the differences are even more intense.

With 350ug I can hardly see reality anymore due to all those colorfull reflections of anything I look at.

I think the higher the dose the clearer the differences.




namaste said:
Quote:

Might have a go this weekend, all depends on my fragile mental health.  Been eating doses 25+ years.  Lots of work drama, we shall see.


You will find that your mental health will thank you after trying this at 300ug, just yesterday (Friday night) again took 400ug of the 1-actealdehyde LSD with 400g of fresh boiled cactus tea, once again, was blown away by the power of this.

Namaste, thanks for trying this out...you will find this is easy on your mental health...There is Zero anxiety, zero tenseness, zero wandering thoughts, no "neural overload" feeling like with normal LSD...deep mental space, pure psychedelic bliss. Replacing the "electricity" of LSD with calm, profound beauty enhancement to the nth degree and visuals way beyond normal LSD.

The comeup is smooth and relaxing like with cactus, no sudden drop off like with acid as it lasts much longer than acid with a warm gentle transition back to reality over a long period of time. Like a long warm hug and embrace.

With closed eyes, high speed movies played in color in the visual plain, flowers, animals, beautiful people, vast meadows and gardens, grand architecture including palaces and interior decorations within them. I climbed the steps of one of these palaces surrounded by art carvings of animals to the left and right of all the steps leading up to the entrance. Mind blowing visions.

With open eyes, colors were once again out of this world and impossible for hours on end, the beauty was infinite as patterns formed everywhere and inside the tracers when I moved my hand I once again saw colored fractals inside them, extremely powerful visuals and transcendence. I never see fractals inside tracers on normal LSD, just shadows of the hand.

This is the only way I will take acid from now on till I die. Extremely beautiful experience with none of the side effects of normal acid.


Edited by tregar (08/16/20 10:15 AM)


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26885466 - 08/17/20 05:51 PM (3 years, 5 months ago)

We now have confirmation :thumbup: from another person here at Shroomery that this works (see other drug discussion or ODD part of forum):

Namaste said:
Quote:

I think you're on to something here.  It was extremely chill.  Soft around the edges.  When I started coming down, it felt like 10 years of therapy.

I remembered good times, felt compassion.  Listened to music I haven't listened to in years.  Thought about friends, was at peace in a way that I haven't felt before.

The stars formed into animated constellations.  My Bodhi statue began to juggle.  I saw the Perseidies meteors not just out of the corner of my eyes but right over my face while lying in a hammock.  Saw the entire movement from start to finish.  They looked like giant arrows.

Stayed awake all day, went out to visit friends.  It was very happy nostalgia.  Sometimes larger doses make me totally black out.  Not this time, I was awake and aware.  No primal fear or paranoia.

TWM
I used McCormick brand peppermint, not spearmint, and Holland House brand Sherry.  It did feel 'altered', seems to extend the duration too.  Felt like I was still peaking seven hours after dropping.  Sometimes I get a cracked out, confused feeling, not this time.

Haven't seen neon colors like that since the one and only time I was puddled.

Sunday's are generally filled with dread and depression for the following week.  Experienced none of that.  Just a long lasting afterglow.  Still in a great mood now.  I did get a pretty severe headache but I also drink like it's my job, and I am on a SSRI.

Been thinking about Ephesus and Pergamon, not sure if thats subliminal or coincidence.  :shrug:

Going to wait 3-4 months and repeat.

Give this a go!



Thank you Namaste!:smile: :smile: :smile: Namaste converted 300ug.

Just add Sherry wine and peppermint extract (any brand will do, even McCormick's) to your wife's grocery list. Peppermint extract is found in the spices and extracts isle. Your wife will look at you like WTF? Just tell her you are doing an experiment like the ancient Aztecs and Mayans in South America and Greek Priest used to do at Eleusis in Greece for over 2,000 years. When she tells you "don't ever say that I don't do anything for you". Just tell her "thanks!"

Taylor brand sherry is virtually everywhere, it's the only brand of Sherry wine my grocery store carries. One bottle will last you a lifetime. It is at ph=4 like the 1992 adducts study calls for, and it contains average 5mg acetaldehyde per 15ml or 1/2 shot glass like we use in the experiment, just like what the study requires (around a 0.1% acetaldehyde solution).

There is a picture of the Sherry wine in pic #1 on post #1, right behind two of the home grown cactus I grew and cut from top of existing cactus. I have found out I like to take 300 to 400ug of the 1-acetaldehyde LSD with 400g fresh (no core) of the cactus (equivalent of 400mg mescaline) cause it makes it feel like 700mg of mescaline. Whereas LSD + cactus just feels like "acid + cactus" nothing too terribly special of a combination, but the 1-acetaldehyde LSD with cactus--->now that is something very special.

Below the pic of the Taylor brand sherry and cactus you will see "double morning glory planters". Each planter is 17" wide x 15" tall with 7 foot tall round welded fence, each contain 15 plants. When I first brought the planter and fence home, my wife looked at me like I was crazy, like the scene in "Close encounters of the 3rd kind" where Richard Dreyfus raids his neighbors's chicken coop for a piece of fence to build a replica of the "Wyoming Devil's Tower." This same experiment also works with cold water acidified extracts of morning glory seeds, transforming the LSH and penniclavine to 1-acetaldehyde LSH & penniclavine. I did this same thing over 22 years ago with mg seeds.

The ancient Aztec and Mayan also normally added the fresh or dried morning glory extract to wine or liquor as well, notes Shultes on page 515 of "Encyclopedia of Psychoactive Plants" by Ratsch. The ancient Greek Priest would add fresh mint to the entheogenic brew consisting of fresh claviceps paspali which contains high levels of LSH when fresh as well, transforming the LSH to 1-aceteldehyde LSH, as mint contains 2mg acetaldehyde per 5 drops mint or peppermint extract.

The ancient Aztec & Mayan & Greek Priest were not the only ones to transform their brews...Dr. Shulgin shows how the beta-carboline harmaline transforms into tetrahydroharmine when a vitamin C doner is added to long standing boiling brew...as it donates 2 hydrogen atoms at the indole "N" position, transforming to "NH" as the sleepy dreamy harmaline transforms to the stimulating, euphoric and colorfully visual alkaloid tetrahydroharmine or thh in an issue of "Entheogen Review" questions and answers section with Dr. Shulgin.

This is done by the Santo Daime vegetal group, as none of their brews contain any leftover harmaline (they brew for long periods with added vitamin C) see paper on this at bottom of references under wikipedia entry for tetrahydroharmine by Dr. Callaway 2005. See page 154 with chemical diagrams showing addition at indole N (nitrogen) position to "NH": https://catbull.com/alamut/Bibliothek/various%20alkaloid%20profiles%20in%20aya%20decoction.pdf

Notice the similarity of what is happening above at the nitrogen N position of the indole on the betacarboline harmaline --> transformation to tetrahydroharmine as what is theoretically happening at the nitrogen NH group position of the bottom indole of the ergoline LSD as well, via the donation of acetaldehyde under proper ph=4 acidic conditions over a several hour period with sitting/stirring once per hour.

From Sandoz Labs, where Albert Hofmann also discovered ALD-52:
Quote:

Sandoz labs suggested that ALD-52 might actually have advantages over LSD, reducing any side effects but achieving a stronger trip. Measurements of brain waves while people were taking the two drugs showed that while LSD produced brain waves associated with intense concentration and anxiety, ALD-52 produced brain waves showing a more relaxed mental state.

It was also found to display "twice the anti-serotonin or serotonin blocking power" of normal LSD.

ALD-52 is listed as having a lower (approximately 1/5) intravenous toxicity (in rabbits), a lower approximately one eighth pyretogenic effect, and double the "antiserotonin" effect as compared with LSD. Human experiments have not been well documented.




I have made 1-acetaldehyde LSD at the 300ug dosage, 400ug dosage, and again at the 400ug dosage, all spaced about 2 weeks apart...

There is Zero anxiety, zero tenseness, zero wandering thoughts, no "neural overload" feeling like with normal LSD...deep mental headspace, pure psychedelic bliss. Replacing the "electricity" of LSD with calm, profound beauty enhancement to the nth degree and visuals beyond normal LSD.

LSD feels "man-made" to me and is "analytical" and not very aesthetic, whereas 1-acetaldehyde LSD feels very natural, primitive and infinitely aesthetic (beauty enhancing) like with cactus.

The comeup is smooth and relaxing like with cactus, no sudden drop off like with acid as it lasts much longer than acid with a warm gentle transition back to reality over a long period of time. Like a long warm hug and embrace.

With closed eyes, high speed movies played in color in the visual plain, flowers, animals, beautiful people, vast meadows and gardens, grand architecture including palaces and interior decorations within them. I climbed the steps of one of these palaces surrounded by art carvings of animals to the left and right of all the steps leading up to the entrance. Mind blowing visions.

With open eyes, colors were once again out of this world and impossible for hours on end, the beauty was infinite as patterns formed everywhere and inside the tracers when I moved my hand I once again saw colored fractals inside them, extremely powerful visuals and transcendence. I never see fractals inside tracers on normal LSD, just shadows of the hand.

Appreciation of the beauty of the two on-screen actresses from "to the stars" (new movie on hulu) was euphorically over the top, similar to tripping on cactus. Like being in Heaven, beauty is perceived as being infinite and divine.

This is the only way I will take acid from now on till I die. Extremely beautiful experience with none of the side effects of normal acid.

I did not discover this study, I was directed to it via a vision from a spiritually prominent Shaman, see story further up in post #1. He wanted humanity to know about it.


Edited by tregar (08/18/20 04:10 AM)


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26887706 - 08/19/20 04:14 AM (3 years, 5 months ago)

Namaste said:
Quote:

I think you're on to something here.  It was extremely chill.  Soft around the edges.  When I started coming down, it felt like 10 years of therapy.

I remembered good times, felt compassion.  Listened to music I haven't listened to in years.  Thought about friends, was at peace in a way that I haven't felt before.

The stars formed into animated constellations.  My Bodhi statue began to juggle.  I saw the Perseidies meteors not just out of the corner of my eyes but right over my face while lying in a hammock.  Saw the entire movement from start to finish.  They looked like giant arrows.

Stayed awake all day, went out to visit friends.  It was very happy nostalgia.  Sometimes larger doses make me totally black out.  Not this time, I was awake and aware.  No primal fear or paranoia.

TWM
I used McCormick brand peppermint, not spearmint, and Holland House brand Sherry.  It did feel 'altered', seems to extend the duration too.  Felt like I was still peaking seven hours after dropping.  Sometimes I get a cracked out, confused feeling, not this time.

Haven't seen neon colors like that since the one and only time I was puddled.

Sunday's are generally filled with dread and depression for the following week.  Experienced none of that.  Just a long lasting afterglow.  Still in a great mood now.  I did get a pretty severe headache but I also drink like it's my job, and I am on a SSRI.

Been thinking about Ephesus and Pergamon, not sure if thats subliminal or coincidence.  :shrug:

Going to wait 3-4 months and repeat.

Give this a go!


Namaste thanks a million for your report, you are the 2nd person on the planet besides myself to give this a go.

So cool Namaste that you watched the meteor shower outside, as the Perseidies are active every year from July 14 to August 24, according to NASA. You also mention that you saw "neon colors like you have not seen in ages" and that "you did not experience the depression which sometimes follows days later".

That's another thing I love about this 1-acetaldehyde LSD, it is extremely colorful, way more colorful than acid, more similar to mescaline in that respect. For hours with open eyes I see impossible out of this world neon colors, reminds me of Ayahuasca or Mescaline with the colors. I have made this at 300ug, 400ug, and again at 400ug, all spaced around 2 weeks apart. I also do not experience the typical mood drop 2 days later, but still feel pretty darn good days later...I also like the fact that it last around double the time that acid does, I am also still peaking way past 4 hours later..I get "double the fun" out of this compared to acid. I never liked the way acid ended so abruptly, I prefer how this last way longer, just like cactus which lasts way longer than acid. I am taking this again for the 4rth time tonight, as I work all weekend, and today and tomorrow is my "weekend" as I work long shifts.

I have a strong suspicion that  1-acetaldehyde LSD does not work thru the 5-ht2a receptor, but rather shifts the receptorome or radio ligand binding "away from 5-ht2a" and towards the adrenal A2A, A2B & A2C receptor binding which is the dominace or habitat of mescaline, dmt, and psilocin, see color chart on page 1. That's why 1-acetaldehyde LSD is more colorful, zero anxiety & tenseness, more visual, amazing mental headspace.

LSD feels "man-made" to me and is "analytical" and not very aesthetic, whereas 1-acetaldehyde LSD feels very natural, primitive and infinitely aesthetic (beauty enhancing) like with cactus. LSD induces "intense concentration" and "anxiety" whereas this produces "over the top" appreciation for beauty and profound visuals similar to how mescaline takes these same qualities to the nth level.

TWM said:
Quote:

Also tregar, please do not take my posts as "doubt".  I have followed your posts immanently since 2012 when you discovered HPBCD coupling with 25i's for oral.  And as an amazing discovery as that was, and revolutionzed the world - it was ended up being only a scientific discovery because those series were awful.

But regardless, here I am immanently following all your posts, and this one.  And I hope that if this legitimate, you will let me help you realize that with empirical and concrete evidence.  Empirical in the sense that I have a distinct gift for psychedelic sensitivity as well as many powers to concretely prove this if possible.

I am very excited to host this experiment as soon as possible.


I look forward to hearing your results, glad you have 500ug soaking (you said you were going to take 1/2 of it), just use 5 drops of the McCormick's brand peppermint extract or whatever you can find at grocery store.

Note (1): Make sure your sherry wine is cold before you use it, it contains 5 mg acetaldehyde per 15ml or 1/2 shot glass. Acetaldehyde boils off at 68 degrees F, or slightly below room temp, so keep 1/2 shot glass of it in fridge at all times until you consume. It is also at ph=4 which is what 1992 adducts study calls for, researchers said "the lower the ph, the faster the reaction."

Note (2): Menthol is largest ingredient in peppermint extract and causes cytochrome P450 enzyme inhibition in the liver, which is involved in the metabolism of exogenous chemicals. This may have a potential effect in preventing the breakdown of 1-acetaldehyde LSD. Peppermint extract also contains 2mg water soluble acetaldehyde per 5 drops.

See my comments above how Dr. Shulgin explains how the betacarboline harmaline converts to tetrahydroharmine via the donation of 2 hydrogen atoms from "vitamin C doner" via stirring and boiling for many hours, same way Santo Daime brew their Ayahuasca for long periods with added vitamin C, tables and charts & link to paper given above with chemical diagram explaining the chemical conversion process via the addition at the indole "N" position, changing to "NH".

See my story on Post #1 (page 1) about how a Shaman lead me to the 1992 adducts study in a 20 minute vision, He wanted all of humanity to know about this, as this is the way the Aztecs would prepare their morning glory seed extract, normally adding it to liquor for the conversion to happen either externally or "in vivo" in the liver.

Note (2) Page 515 "Encyclopedia of Psychoactive Plants" Christian Ratsch: "The fresh or dried morning glory seeds normally are added to alcoholic drinks (sugarcane liquor; c. alcohol), tepache (maize beer, chicha), and balche' (Schultes 1941, 37)."


Edited by tregar (08/19/20 04:44 AM)


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26888233 - 08/19/20 11:36 AM (3 years, 5 months ago)

If you don't hear from me again, it's because my other love is bodybuilding, been lifting weights since age 22, 220lbs, 12% bodyfat, competed in several competitions. I believe in physical, mental & spiritual health all working together. Better living thru chemistry. You may have seen me, been on cover of Twinlab's "Ironman" in my early 30's, posed with 2 women on the cover. Was a professional lifeguard for a decade.

Stay true to yourself, peace, love & music

http://friskyradio.com

Not me below, but showing Ironman magazine so you know what it looks like.


Edited by tregar (08/19/20 11:51 AM)


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26888776 - 08/19/20 04:33 PM (3 years, 5 months ago)

Once again, I overshot. 300ug is all you need of this, PLENTY STRONG for any occasion.


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26889250 - 08/19/20 10:14 PM (3 years, 5 months ago)

Namaste said:
Quote:

Haha

Thanks for sharing the recipe.  I really do believe that there is a conversion into a new substance, that it's acting on different receptors.  That was one of the best trips of my life and I dose several times/year.

Blessed be




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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26889461 - 08/20/20 05:25 AM (3 years, 5 months ago)

I go back and forth between shrooms and acid every month or two. I have been on an acid kick lately and have a three day camping trip next week. If I can get the supplies together before then, I will definitely give this a go. My tabs are supposedly 150 ug but I have sincere doubts so considering going with 2.5 tabs. Will definitely report back if I make it happen.


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: Sharp-Inflation]
    #26894867 - 08/23/20 07:16 AM (3 years, 5 months ago)

Thanks for trying this out Sharp-Inflation.

Before I leave, just wanted to say:

gannetsarewe said:
Quote:

So has anybody else tried this. I don't want to waste my scarce acid or have to drink the rest of my bottle of sherry wine, not sure which is worse.



You're acid will not be wasted, when dissolved into wine, it does not disappear or disintegrate. It will remain 100% active, only it will be converted to a completely different substance after 3 hours with far reaching different activity from normal LSD. 1 bottle of sherry wine will last a lifetime, as will the peppemint extract. Read again above what Dr. Shulgin saids happens at the indole N position of the betacarboline harmaline, converting to "NH" with the donation of 2 hydrogens from vitamin C doner, transforming into tetrahydroharmine over several hours in acidic conditions. Here we are doing the same thing, only using "acetaldehyde donor" at the indole NH position.

If you don't want to believe me then listen to Namaste (he took acid hundreds of times in the past, just like myself, his full trip report is below with 300ug of 1-acetaldehyde LSD):
Quote:

Thanks for sharing the recipe. I really do believe that there is a conversion into a new substance, that it's acting on different receptors. That was one of the best trips of my life and I dose several times/year.

Blessed be

I think you're on to something here. It was extremely chill. Soft around the edges. When I started coming down, it felt like 10 years of therapy.

I remembered good times, felt compassion. Listened to music I haven't listened to in years. Thought about friends, was at peace in a way that I haven't felt before.

The stars formed into animated constellations. My Bodhi statue began to juggle. I saw the Perseidies meteors not just out of the corner of my eyes but right over my face while lying in a hammock. Saw the entire movement from start to finish. They looked like giant arrows.

Stayed awake all day, went out to visit friends. It was very happy nostalgia. Sometimes larger doses make me totally black out. Not this time, I was awake and aware. No primal fear or paranoia.

TWM
I used McCormick brand peppermint, not spearmint, and Holland House brand Sherry. It did feel 'altered', seems to extend the duration too. Felt like I was still peaking seven hours after dropping. Sometimes I get a cracked out, confused feeling, not this time.

Haven't seen neon colors like that since the one and only time I was puddled.

Sunday's are generally filled with dread and depression for the following week. Experienced none of that. Just a long lasting afterglow. Still in a great mood now. I did get a pretty severe headache but I also drink like it's my job, and I am on a SSRI.

Been thinking about Ephesus and Pergamon, not sure if thats subliminal or coincidence. 🤷

Going to wait 3-4 months and repeat.

Give this a go!



Krystle Cole from the book "Lysergic":
Quote:

"Isn't Ergot what Socrates used to take at Eleusis?" I thought it was kind of cool to be taking something that the founders of our democracy used to take, but that our current democracy has made illegal.

LSD chemist Todd Skinner replied "Yes, except for he did a water infusion of the ergot, instead of alcohol." Todd had prepared 6 jugs of ergot wine and stored them for many years.

Krystle Cole's "ergot wine" experience (several pages long) in the book "Lysergic", reported that she saw constantly rotating holographic Sanskrit or Arabic & Zodiac symbols, floating in a circle around Todd's head.



Even LSD chemist Todd Skinner added ergot to wine, then consumed. He knew alkaloid conversion was taking place as well, years before I caught onto it.


Edited by tregar (08/23/20 07:34 AM)


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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: tregar]
    #26895230 - 08/23/20 11:19 AM (3 years, 5 months ago)

Just got my supplies ready for my camping trip this week. My girl got the only brand of sherry they had plus the peppermint extract. Will be using this tek on ~375 ug of acid (2.5 tabs of supposedly 150 ug acid) for my camping trip Thursday. Plan to just be in nature with my girl who will be on shrooms. Lots of good music and those cool little packets that make fire change colors. That combined with some nice weather should make for an excellent setting for this experiment. Looking forward to reporting back on how it goes.



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Re: Theoretical at-home conversion of LSD to ALD-52 (1-acetyl LSD) in 1 step [Re: Sharp-Inflation]
    #26895694 - 08/23/20 04:49 PM (3 years, 5 months ago)

Mods should consider locking this thread since it's double posted in ODD and entirely hypothetical.


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