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psysearch
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LSD and SSRI/Prozac
#26685938 - 05/21/20 03:16 PM (3 years, 8 months ago) |
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I have a friend that wants to try LSD and he is currently taking Prozac. I've researched this a lot and it generally seems to be that it might weaken the dose a bit and it's best to come off the meds for a while first, although others say to not come off as then it could make for tripping with a depressed mindstate. Some others say being on an SSRI increases the strength, others that it makes little difference.
I'm just fishing for more opinions really as looking to help my friend have the best possible experience. He's familiar with altered states and think that LSD could really help him.
Thanks for any input (:
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alephdog
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Re: LSD and SSRI/Prozac [Re: psysearch]
#26687350 - 05/22/20 06:19 AM (3 years, 8 months ago) |
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He's probably better off smoking weed and SMALL amounts of salvia alongside you guys.
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psysearch
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Re: LSD and SSRI/Prozac [Re: alephdog]
#26687682 - 05/22/20 09:10 AM (3 years, 8 months ago) |
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He's more than acquainted with weed, I have no experience with salvia so couldn't recommend it to anyone personally.
He's taken MDMA and had decent effects and also had 2C-B which he definitely tripped off and even got a good afterglow the next day. Although we did insufflate quite a lot lol. I just think that psychs could really help him, possibly even get off SSRIs in the long-term if he wanted to, with the help of his doctor of course.
I hear shrooms have less interaction with Prozac in particular so maybe that's a good option.
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alephdog
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Re: LSD and SSRI/Prozac [Re: psysearch]
#26688312 - 05/22/20 02:27 PM (3 years, 8 months ago) |
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Don't know if there's anything specific between prozac and shrooms, I would try it another time he's likely to have little effect.
Salvia is great in low doses. A lot of people fall prey to the thinking you need a full blown trip, but I don't recommend this especially the first few times or as a general habit. The weakly dopamine effects kick in at a surprisingly low dose. I have small measuring spoons tad/dash/pinch, the pinch is 1/16 tsp or 40mg and I find that mixing a pinch of 10x in with a bowl or a joint is nice. You can SLOWLY take hits off it every few minutes, and you end up with a very mellow body high and zen-like feeling with zero visuals or minimal mindfuck. It's an interesting drug all to itself, and in my experience one of the few out there that sits well with psychiatric patients.
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psysearch
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Re: LSD and SSRI/Prozac [Re: alephdog]
#26694974 - 05/25/20 01:04 PM (3 years, 8 months ago) |
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Interesting, thanks for the info.
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DJ Ed
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Re: LSD and SSRI/Prozac [Re: psysearch]
#26695106 - 05/25/20 02:17 PM (3 years, 8 months ago) |
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Prozac is an SSRI. It works on the 5HT-2a serotonin receptors. Psilocin also works on the 5HT-2a receptors. Of the receptors are currently blocked by h]the SSRIs , they will not accept the psilocin. Poor trip, that’s if you trip at all. You need to be clear of SSRIs before you trip
-------------------- “It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.” Michael Pollan: How To Change Your Mind “The problem is not to find the answer, it’s to face the answer.” Terence McKenna

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clack3rz
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Re: LSD and SSRI/Prozac [Re: DJ Ed]
#26695698 - 05/25/20 08:23 PM (3 years, 8 months ago) |
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Quote:
DJ Ed said: Prozac is an SSRI. It works on the 5HT-2a serotonin receptors. Psilocin also works on the 5HT-2a receptors. Of the receptors are currently blocked by h]the SSRIs , they will not accept the psilocin. Poor trip, that’s if you trip at all. You need to be clear of SSRIs before you trip
I think this is my issue. I gave shrooms a go recently and I ate quite a bit 3-3.5 and had basically no affect or effect whatsoever. I take Lexapro, so I think this blocked my trip. I'm going to see about stopping for a period and see what happens on my next 'trip' but will speak to a Dr first about stopping the meds
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DJ Ed
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Re: LSD and SSRI/Prozac [Re: clack3rz]
#26695978 - 05/25/20 11:45 PM (3 years, 7 months ago) |
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It is always worth chatting to your doctor; the withdrawal will depend on many factors, notable the dose you have taken and for how long. Ultimately, I failed with my doctor, on numerous occasions - the tapering down was just too slow, and I wanted it over with. So in the end weaned myself off from 100mg sertrline per day to zero within about 3 weeks! But that was all at my risk, don’t do as I did without advice from a professional
-------------------- “It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.” Michael Pollan: How To Change Your Mind “The problem is not to find the answer, it’s to face the answer.” Terence McKenna

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clack3rz
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Re: LSD and SSRI/Prozac [Re: DJ Ed]
#26698460 - 05/27/20 02:52 AM (3 years, 7 months ago) |
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Quote:
DJ Ed said: It is always worth chatting to your doctor; the withdrawal will depend on many factors, notable the dose you have taken and for how long. Ultimately, I failed with my doctor, on numerous occasions - the tapering down was just too slow, and I wanted it over with. So in the end weaned myself off from 100mg sertrline per day to zero within about 3 weeks! But that was all at my risk, don’t do as I did without advice from a professional 
Thanks mate, appreciate the advice from experience.
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DJ Ed
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Re: LSD and SSRI/Prozac [Re: clack3rz]
#26698699 - 05/27/20 06:38 AM (3 years, 7 months ago) |
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Also should have noted, I’d been on the SSRIs for 7 years. In all my attempts to taper off under medical supervision, I never got past day 9 (must have been when the withdrawal started to get really soul destroying). That’s why I did it myself, I mean I wasn’t in hospital when under medical supervision, the doctor just told me what to do then sent me home. 9 f=days later I’d be back for a new prescription.
When I set my own timetable, I knew the end was in sight, so it made it more bearable. And during the 5 months abstention it took me before I could trip fully, I focussed my attention on learning to grow.
My timetable was;,week 1 half dose, week 2 quarter dose, week 3 quarter dose every other day, week 4 clear
-------------------- “It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.” Michael Pollan: How To Change Your Mind “The problem is not to find the answer, it’s to face the answer.” Terence McKenna

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clack3rz
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Re: LSD and SSRI/Prozac [Re: DJ Ed]
#26699851 - 05/27/20 04:11 PM (3 years, 7 months ago) |
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Yep - I've been on them for a few years myself now I know that feeling when these meds are missed for several days in a row - been there before. I've committed to weening off them to see how I react first after discussions with the Dr. Then I'll see how I go from there. I was also looking into growing as well.
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