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Shop: PhytoExtractum Maeng Da Thai Kratom Leaf Powder   Unfolding Nature Unfolding Nature: Being in the Implicate Order

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OfflineLogicaL ChaosM
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Can you Sacrifice 1 Hit for Science? (LSD Experiment)
    #26609830 - 04/18/20 08:21 AM (3 years, 9 months ago)

So, I have this transdermal experiment I would like to try with LSD.

The basis of the Experiment is to see if LSD is transdermally-active thru the skin. Theres stories that it is, but I wanna see if its actually a practical method to take LSD.

This article explains more about Transdermal absorption: https://ndnr.com/mindbody/dermal-absorption-of-essential-oils/

Some places of the body have higher-than-average transdermal absorption properties due the skin of the area:

Quote:

Regarding location of the skin application, areas with the thinnest epidermal layers, and areas rich in sebaceous glands, sweat glands, and hair follicles, prove to be the best areas of transdermal absorption. These locations include face, neck, scalp, and wrist.




My experiment is to:

Place 1 hit of LSD blotter on the skin, on either the face, neck, scalp or wrist
Place a Band-Aid soaked with purified water/spirit alcohol on top of it of the hit to hold it in place and to aid in LSD absorption.
See if the LSD hit is absorbed thru the skin

Can anyone provide a self-experiment trial to see if it works?

I plan on doing the experiment as well in the near future as well.


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OfflineSynKyd
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos] * 2
    #26610107 - 04/18/20 10:31 AM (3 years, 9 months ago)

I know someone who was involved in a spill while laying blotter and was permanently left with some issues as a result, many years later this person is still rather twitchy and spastic. I don’t think this experiment is really necessary, transdermal is very definitely proven ROA for lsd.

Recent article about someone getting very deep off some old music gear with lsd on it was also going around awhile back.

I don’t think water is a good idea though in your proposal, for what it’s worth won’t it break down the L?


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OfflineLogicaL ChaosM
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: SynKyd]
    #26610112 - 04/18/20 10:33 AM (3 years, 9 months ago)

Interesting.

I was also thinking of using a plant extract oil. Might be a better choice right?

The transdermal route experiment is also to better understand the effectiveness and if it works on everyone.


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Invisibleninja cat 09
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos] * 1
    #26610248 - 04/18/20 11:35 AM (3 years, 9 months ago)

I don't have access to it myself at the moment, but it sounds interesting! A good place is behind the ear since there's a bit of capillarity there. You can put a pinch of tobacco there and get a very mild stimulant effect (if you're not a smoker).

Water only breaks down LSD if it has chlorine in it, which distilled water won't.


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OfflineLogicaL ChaosM
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: ninja cat 09] * 1
    #26610257 - 04/18/20 11:37 AM (3 years, 9 months ago)

Very cool! Behind the ear, check :takingnotes:

Yes, use only distilled/purified water. NO TAP WATER. BAD.


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Invisibleopenmind
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos] * 2
    #26610497 - 04/18/20 12:55 PM (3 years, 9 months ago)

This should be common knowledge by now around here lol.....Your "experiment" has been done before, and commented on by doctors and legends within the LSD "scene"/historical figures.



Quote:

Dr. Dave Nichols

"I've made LSD in my lab on many occasions for research purposes, possibly in not so meticulous a manner as Albert Hofmann. Nothing ever happened. I had several graduate students who made LSD as an intermediate for projects. No accidental ingestion of LSD ever occurred. A technician in my lab makes it routinely because we use it as a drug to train our rats. He's learned by experience that he never gets high, nothing ever happens. And yesterday I was talking to Nick Sand, and Nick said, "I made a solution of LSD in DMSO…" DMSO (dimethyl sulfoxide) is a chemical that greatly enhances absorption of other chemicals through the skin -- he says, "…I painted it on my skin. Nothing happened." A concentrated solution and nothing happened!





Quote:


An esteemed underground LSD chemist arrested in '05, Donnie Shackelford, is quoted in an unfinished book on black market LSD production by Tim Scully. Here's an excerpt from the interview.

Tim Scully said, "Did you ever get dosed through your skin in the lab". Donnie Shackelford replied, "No, I have accidentally dosed myself while laying sheets, I either touched my eye, or mouth. But the answer to your question is no, you cannot be dosed through the skin. I never wore gloves in any procedure unless lye is used and it isn’t in this procedure. I learned the hard way dropping a flask with 20g of LSD in it. I was extremely upset. I’ve had it all over my hands many, many times. I was there when Dr. Nichols basically called bullshit on the good doctor at Mindstates 60th anniversary".







I've heard some quote from some other more modern/recent chemists that also had something to say about LSD not absorbing through skin, and that he never gets "dosed" when working in the lab and synthing LSD....Can't find that one though.



I too have heard lots of "stories" and folklore/myths about people getting a bunch of liquid on their hands and end up tripping, stories like that have been around for several generations now lol...There's always someone that knows a person who spilled a vial or got a bunch of liquid on their skin somehow and they ended up tripping, usually the story also goes on about the person going "insane" or tripping for multiple days or the person "never coming down" or the person was "never the same" (I've heard the same sort of story so many times from lots of different people/places over the years, I find them all very hard to believe)...Perhaps those people touched around their eyes/nose/mouth or any sort of mucous membrane, or perhaps they are just "stories"/myths that people repeat, but all of the figures/sources that I respect say that LSD does not absorb through the skin.





-OM

.


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OfflineLogicaL ChaosM
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: openmind]
    #26610531 - 04/18/20 01:13 PM (3 years, 9 months ago)

Good point. It has been done before.  But have you tried it personally? Have you tried to make it work?


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Invisibleopenmind
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos] * 1
    #26610580 - 04/18/20 01:34 PM (3 years, 9 months ago)

Quote:

LogicaL Chaos said:
Good point. It has been done before.  But have you tried it personally? Have you tried to make it work?






I can't say I have tried it.

I have no reason to, putting it under my tongue works great lol.

Scientist/chemists/doctors that I respect & trust have mentioned it doesn't work, so I don't have much interest in trying it.

Even if it did work, I'd continue to place my dose right underneath my tongue.




But props for giving it a try :thumbup:






-OM

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OfflineLogicaL ChaosM
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: openmind] * 1
    #26610583 - 04/18/20 01:35 PM (3 years, 9 months ago)

Fair enough.

Im gonna dose my skin tomorrow, for science! :mushroom2:


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OfflineTyperwritermonky
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos]
    #26610771 - 04/18/20 02:57 PM (3 years, 9 months ago)

The way people get high when laying blotters or being around crystal L is that as soon as the crystal is exposed to the general air - slight currents will pick up very small amounts that will enter through the mouth and nostrils.  Remember it takes mcg to get one high.  When laying blotters with alcohol, the alcohol whence the crystal has been dissolved in it will evaporate slowly yet immediately, and then once again the LSD enters through the mouth and nostrils when accidentally inhaled.

It is not transdermally active, and openmind's post is written perfectly.


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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos] * 1
    #26611149 - 04/18/20 05:54 PM (3 years, 9 months ago)

I'd be interested to hear the results of someone actually trying this. Coaster claimed that it was active after he stuck his hand in some and claimed to trip balls as a result, but you never know. After all, there are lots of professionals like those mentioned in this thread who claim it isn't active through the skin. If it is, I suspect maybe it has to be in a solution of water or alcohol or something to be active.

I think the origin of this myth might even be from Hofmann claiming to have accidentally ingested some which there's good reason to believe he was lying about. If we could prove it can't be, then you could probably prove that Hofmann's claim about accidentally ingesting some is inaccurate.

Anyway, it'd be interesting if we got a bunch of people to try it so we could put the issue to rest. I wouldn't necessarily trust just one report from someone, we'd need to get a large variety of people to try it to say for sure.


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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: nooneman]
    #26611176 - 04/18/20 06:06 PM (3 years, 9 months ago)

I suggest the mouth: fast, efficient, obvious, already hanging open.

and what openmind quoted of Dave Nichols and Donnie Shackelford etc. etc. etc.


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OfflineLogicaL ChaosM
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: nooneman]
    #26612085 - 04/19/20 05:09 AM (3 years, 9 months ago)

Im going to try this right now.

My plan is one hit, on the inner forearm, soaked in Lemon Bitter liquid, then covered with medical tape.

T-minus 10 minutes for 4:19am PST.....


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OfflineLogicaL ChaosM
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos]
    #26612112 - 04/19/20 05:57 AM (3 years, 9 months ago)

I placed the 1 hit on my left forearm at 4:19AM with lemon bitters dripped onto the hit. Some of the lemon bitters ran around my arm, so I used my right hand to capture the liquid and rub into my forearm skin.

Its been 40mins and I definitely felt some come up feelings. Even had very minor physical nausea. I have that feeling of coming up energy, similar to eaten but much more subtle/gentle. It has a dreamy, subtle feeling to it. Its interesting. Might have to add another hit to my right arm....


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Offlinesporecap
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos] * 2
    #26612183 - 04/19/20 07:05 AM (3 years, 9 months ago)

I think you need a double blind test to rule out the placebo effect, you might actually be tripping harder from that than a possible transdermal absorption :wink:
Recent relevant study: Study Participants Experience Psychedelic Effects after Receiving Placebo
Someone else prepares the blotters, one with and one without LSD and gives you them in random order?


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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: sporecap] * 2
    #26612629 - 04/19/20 10:31 AM (3 years, 9 months ago)

I soaked my thigh (acidentally, which should go without saying...) in a solution containing approximately 4000ug and after a lot of saying prayers and freaking out and trying to get home as quickly as possible from a nearby friend's house... nothing happened.  Also a handful of times before and after got liquid on my fingers and nothing.  God... this forum makes me want to dose every time I get on here.


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OfflineLogicaL ChaosM
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: alaskappalachian]
    #26612636 - 04/19/20 10:35 AM (3 years, 9 months ago)

Really? interesting.

Well it is Bicycle day. Dose it! :lsd:


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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos] * 1
    #26612657 - 04/19/20 10:43 AM (3 years, 9 months ago)

Quote:

LogicaL Chaos said:
Really? interesting.

Well it is Bicycle day. Dose it! :lsd:




I just saw that! :trippinbawelz:  Nothing here at the house to dose lol.  I have a good friend in town proper that has some but he's an old guy with COPD so he's not taking any houseguests atm.  Don't blame him.  He sounds like somebody trying to drive a diesel underwater, God bless him.  But yeah... I was astounded that not only did I not have to go to the ER, I didn't feel ANYTHING (save for the pain of losing a...lot...of product).  Oh yeah, and happy Bicycle Day  :letyourspiritsoar:  you wonderful people!


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OfflineLogicaL ChaosM
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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: alaskappalachian]
    #26612662 - 04/19/20 10:45 AM (3 years, 9 months ago)

:lol:

:lolwut:


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Re: Can you Sacrifice 1 Hit for Science? (LSD Experiment) [Re: LogicaL Chaos] * 1
    #26612723 - 04/19/20 11:11 AM (3 years, 9 months ago)

Quote:

LogicaL Chaos said:
:lol:

:lolwut:




Nani


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