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OfflineEnkidu
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Zoloft swap to microdosing mushrooms
    #26582197 - 04/06/20 05:12 PM (3 years, 9 months ago)

So my gf is on zoloft

We want to try swapping it out to mushrooms

Ive microdosed a lot, but not too familiar with zoloft

I was thinking she needs a certain amount of time to ween off zoloft while slowly introducing mushrooms

Anyone have specefics on how much or how long it takes to ween off the zoloft in a healthy way while introducing mushrooms?

She takes 150mg zoloft daily right now

Gracias amigos


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Within You , Without You


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InvisibleThe Blind Ass
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Re: Zoloft swap to microdosing mushrooms [Re: Enkidu]
    #26582222 - 04/06/20 05:20 PM (3 years, 9 months ago)

Fucking hold your horses.


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OfflineEnkidu
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Re: Zoloft swap to microdosing mushrooms [Re: The Blind Ass]
    #26582347 - 04/06/20 06:06 PM (3 years, 9 months ago)

Valuable contribution


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OfflineDJ Ed
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Re: Zoloft swap to microdosing mushrooms [Re: Enkidu]
    #26583033 - 04/07/20 12:01 AM (3 years, 9 months ago)

There are many factors involved with SSRI use,,but apart from genetics are manly around the dose and duration. 150mg is a high dose. Basically SSRIs block the same 5ht-2a receptors that psilocin uses, so in the main, you can’t trip very well while SSRIs are still in your system; it took me 5 months off SSRIs before I successfully tripped, having been on 100mg sertraline (Zoloft) for 7 years.

I can’t tell you how to wean your girlfriend off, because that would be irresponsible of me; seek medical supervision. I tapered off half dose for 1 week, quarter dose for one week, then quarter dose every other day 3rd week. Nightmare withdrawal symptoms for about 6 months.

Good luck
DJ Ed


--------------------
“It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.”
Michael Pollan: How To Change Your Mind

“The problem is not to find the answer, it’s to face the answer.”
Terence McKenna



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OfflineNorthernerM
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Re: Zoloft swap to microdosing mushrooms [Re: DJ Ed]
    #26583162 - 04/07/20 02:37 AM (3 years, 9 months ago)

It really depends how long she has been using it for as well.

I'm not going to clog up your thread with my own family's horror stories, but I can assure you if she's been on it for years she may have to taper over years as well to actually get off the stuff. The problem is the med companies don't make the right sized doses once you start getting smaller, as the taper needs to be as little as 10% of the current dose reduction, per previous month, until it's finally so small that the person just takes the leap and stops. A period of hell is unavoidable but can be greatly reduced like this.

Hit me up anytime Enkidu. I'm always there for you my friend.


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The nearest we ever come to knowing truth is when we are witness to paradox.


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OfflineEnkidu
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Re: Zoloft swap to microdosing mushrooms [Re: Northerner]
    #26583445 - 04/07/20 08:25 AM (3 years, 9 months ago)

Appreciate it Northerner.

And thanks dj ed

Ill have to do some more research.

Shes mainly used it for seasonal depression and hasnt been on it super long.

She said in the past she just quit taking it cold turkey.


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OfflineThe Mycologist
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Re: Zoloft swap to microdosing mushrooms [Re: Enkidu]
    #26583458 - 04/07/20 08:37 AM (3 years, 9 months ago)

Good luck. Our understanding of psychology and neuroscience is so lacking. We just try stuff and use it if it works.

Hopefully the shrooms end up working once she gets tapered.


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"That you are here—that life exists, and identity;
That the powerful play goes on, and you will contribute a verse.”
― Walt Whitman, Leaves of Grass
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OfflineDJ Ed
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Re: Zoloft swap to microdosing mushrooms [Re: Enkidu]
    #26583679 - 04/07/20 10:37 AM (3 years, 9 months ago)

The only reason I tell you to use medical supervision, is because, apparently, some people can have bad reactions coming off SSRIs.

First thing you should be aware of, is there is no long term data on the effects SSRIs have on humans, only short term data sufficient to pass all the FDA regulations etc. So we don’t know how dangerous these things are coming on and coming off them.

I was once advised, the length of time of the withdrawal should match the length of time you’ve been on the medication. So for me that would have been 7 years....of withdrawals symptoms!

So I went cold turkey over three weeks, and told my doctor once I had reached 0mg.

Take care
DJ Ed


--------------------
“It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.”
Michael Pollan: How To Change Your Mind

“The problem is not to find the answer, it’s to face the answer.”
Terence McKenna



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OfflineEnkidu
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Re: Zoloft swap to microdosing mushrooms [Re: DJ Ed]
    #26584646 - 04/07/20 06:37 PM (3 years, 9 months ago)

You lowered the dose over the course of 3 weeks?

You think she should start the mushrooms now, like twice a week or something


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OfflineDJ Ed
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Re: Zoloft swap to microdosing mushrooms [Re: Enkidu]
    #26585312 - 04/08/20 12:03 AM (3 years, 9 months ago)

The only possible “bad” interaction is that the mushrooms will not work and she’ll get a washed out really weak trip. Varying reports on here where some report no differenc at all, ie, can trip fully while also taking SSRIs. So yes why not try mushrooms now. No risk of harming her health...


--------------------
“It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.”
Michael Pollan: How To Change Your Mind

“The problem is not to find the answer, it’s to face the answer.”
Terence McKenna



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OfflineKittlebean
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Re: Zoloft swap to microdosing mushrooms [Re: DJ Ed]
    #26586795 - 04/08/20 04:35 PM (3 years, 9 months ago)

Quote:

Nightmare withdrawal symptoms for about 6 months.




I was on Zoloft for around 12 - 18 months, whilst on it I found that even missing 1 to 2 days would produce some pretty horrible symptoms. Tingling fingers and lips, and "brain zaps" as people call them. Feeling like your head has electricity flowing through it when you move it.

I decided to come off it as I was going to be traveling for a year and couldn't get enough prescribed to last me whilst away. I would advise just coming off very gradually to minimise the withradwel symptoms. I dropped down my dose at slow and steady pace and it wasn't too bad, over the course of about 3-4 months if I remember correctly. I think just observing how she feels at each step, and being prepared to slow down further when weening off if necessary.


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InvisibleThe Blind Ass
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Registered: 08/16/16
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Re: Zoloft swap to microdosing mushrooms [Re: DJ Ed]
    #26586805 - 04/08/20 04:42 PM (3 years, 9 months ago)

Quote:

DJ Ed said:
The only possible “bad” interaction is that the mushrooms will not work and she’ll get a washed out really weak trip. Varying reports on here where some report no differenc at all, ie, can trip fully while also taking SSRIs. So yes why not try mushrooms now. No risk of harming her health...



That’s not the only potential interaction, nor is it the only potentially “bad one”.  At the very least a supervised medical taper by someone who’s actually qualified would be wise and in her best interests.    Messing with the interactions of chemicals that work on the CNS and other sites in the body that it’s dependent upon is regarded as high risk behavior.  Don’t mean to rain on anyone’s parade, but we know nothing of her medical history, why her physician rx’d sertraline and how long she’s been on it total and at what doses.  Even so, my point is, don’t rely on random people on the internet, especially the shroomery, when her physician could easily construct a taper to ween her off in a safe and reliable way.  I’m would say afterwards of it, that the idea of taking mushrooms could be revisited once she’s more stable and settled.

But what do I know.


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InvisibleD3_Myc
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Re: Zoloft swap to microdosing mushrooms [Re: The Blind Ass]
    #26586818 - 04/08/20 04:48 PM (3 years, 9 months ago)

Zoloft was one the worst medications I’ve ever been put on. So happy to be off it now, took me a couple miserable weeks to ween and feel right again.


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OfflineSugabearcrisp
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Re: Zoloft swap to microdosing mushrooms [Re: DJ Ed]
    #26586862 - 04/08/20 05:02 PM (3 years, 9 months ago)

Quote:

DJ Ed said:
The only reason I tell you to use medical supervision, is because, apparently, some people can have bad reactions coming off SSRIs.



A former SO of mine experienced brain zaps coming off of a 6 month stint on these drugs, micro seizures. It went away but took time and was very concerning


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InvisibleD3_Myc
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Re: Zoloft swap to microdosing mushrooms [Re: Sugabearcrisp]
    #26587172 - 04/08/20 07:44 PM (3 years, 9 months ago)

Quote:

Sugabearcrisp said:
Quote:

DJ Ed said:
The only reason I tell you to use medical supervision, is because, apparently, some people can have bad reactions coming off SSRIs.



A former SO of mine experienced brain zaps coming off of a 6 month stint on these drugs, micro seizures. It went away but took time and was very concerning




The zaps and brain splitting headaches are terrible


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OfflineInfraredRick
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Re: Zoloft swap to microdosing mushrooms [Re: D3_Myc]
    #26587755 - 04/09/20 12:28 AM (3 years, 9 months ago)

I've been on 150mg Zoloft for 15 years, and for good reason. Chronic major depression, unspecified. I'm stable, the drug works well for me, and last time I went off it I landed in a psych ward for a fucking week. I'm terrified of going off it again because it prevents suicidal ideation. For me. Other people experience different outcomes with Zoloft. As a SSRI it mutes LSD but if I double up on shrooms I trip just fine and feel great for a week. Everybody is different but my suggestion is to not go off the meds if they are working well. Last,150mg is 3/4 toward the top of the range for Setraline, max dose is 200mg/day. So she's on a heavy amount. It would be very reckless to expect psilocybin to replace Zoloft. She could end up crazy as fuck.


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