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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 - Unreal Numbers [Re: morrowasted]
    #26564281 - 03/28/20 10:15 PM (3 years, 10 months ago)

Press release arrest of man violating isolation order in Maryland

On March 27 at 10:53 p.m., officers responded to the 15000 block of Lukes Lane in Hughesville for the report of a large group of people at a single location in violation of Governor Hogan’s emergency order which prohibits planned gatherings of more than 10 people in response to the COVID-19 emergency. When officers arrived, they observed approximately 60 people at a bonfire. This is the second time officers have responded to this house for a large gathering: On March 22, officers were dispatched to the house for a similar complaint. At that time, the homeowner, Shawn Marshall Myers, 41, was advised of the emergency order and he agreed to disperse the crowd. During the second incident, Myers refused multiple requests to comply with the emergency order. After conferring with the Charles County State’s Attorney’s Office, Myers was subsequently charged with violating the Governor’s order. The CCSO is reminding citizens of the emergency order and urging everyone to comply for the safety, health and well-being of all communities.


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlinemorrowasted
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 - Unreal Numbers [Re: koods] * 1
    #26564292 - 03/28/20 10:29 PM (3 years, 10 months ago)



pittsburgh



https://www.youtube.com/watch?time_continue=12&v=e0G63uzhFP4

funny song called Stay the Fuck at Home


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Invisiblecannabinated
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Registered: 01/03/13
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 - Unreal Numbers [Re: morrowasted]
    #26564298 - 03/28/20 10:38 PM (3 years, 10 months ago)

im jeal of enlils folding at home stats


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Offlinemorrowasted
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 - Unreal Numbers [Re: morrowasted] * 1
    #26564299 - 03/28/20 10:40 PM (3 years, 10 months ago)

these docs are putting ponchos over patients when intubating to prevent aerosolizing of droplets




JCAHO's blood pressure is probably through the roof


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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods] * 1
    #26564301 - 03/28/20 10:40 PM (3 years, 10 months ago)

Quote:

koods said:
.




These were the actual numbers starting at around 100
3/2 105
3/3 125
3/4 159
3/5 227
3/6 331
3/7 444
3/8 564
3/9 728
3/10 1000
3/11 1267
3/12 1645
3/13 2204
314 2826
3/15 3505
3/16 4466
3/17 6135
3/18 8760
3/19 13229
3/20 18763
3/21 25740
3/22 34276
3/23 42663
3/24 52976
3/25 65273
3/26 82135
3/27 101295
Now 121176


Edited by koods (03/28/20 10:42 PM)


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InvisibleTexas Honey BadgerM
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods] * 7
    #26564305 - 03/28/20 10:43 PM (3 years, 10 months ago)

That count is growing way to fast


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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: Texas Honey Badger]
    #26564308 - 03/28/20 10:52 PM (3 years, 10 months ago)

Michigan, Florida, Maryland and Massachusetts are showing growth at that same rate .25

California and New York is now around .15

Washington and Texas are around .10


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlinemorrowasted
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: Texas Honey Badger] * 2
    #26564318 - 03/28/20 11:09 PM (3 years, 10 months ago)

https://www.ncbi.nlm.nih.gov/pubmed/21079686

Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture.

Increasing the intracellular Zn(2+) concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed to interference with viral polyprotein processing. In this study we demonstrate that the combination of Zn(2+) and PT at low concentrations (2 µM Zn(2+) and 2 µM PT) inhibits the replication of SARS-coronavirus (SARS-CoV) and equine arteritis virus (EAV) in cell culture. The RNA synthesis of these two distantly related nidoviruses is catalyzed by an RNA-dependent RNA polymerase (RdRp), which is the core enzyme of their multiprotein replication and transcription complex (RTC). Using an activity assay for RTCs isolated from cells infected with SARS-CoV or EAV--thus eliminating the need for PT to transport Zn(2+) across the plasma membrane--we show that Zn(2+) efficiently inhibits the RNA-synthesizing activity of the RTCs of both viruses. Enzymatic studies using recombinant RdRps (SARS-CoV nsp12 and EAV nsp9) purified from E. coli subsequently revealed that Zn(2+) directly inhibited the in vitro activity of both nidovirus polymerases. More specifically, Zn(2+) was found to block the initiation step of EAV RNA synthesis, whereas in the case of the SARS-CoV RdRp elongation was inhibited and template binding reduced. By chelating Zn(2+) with MgEDTA, the inhibitory effect of the divalent cation could be reversed, which provides a novel experimental tool for in vitro studies of the molecular details of nidovirus replication and transcription.



https://jech.bmj.com/content/67/6/533

Serum 25-hydroxyvitamin D3 and the risk of pneumonia in an ageing general population

These data suggest an inverse effect of serum 25(OH)D3 concentration on the risk of incident pneumonia in the general ageing population.


Probably wont hurt ya to supplement some extra D and Zinc for a bit. :shrug:

I may work in conventional medicine but I definitely dabble in other stuff (obviously). I've been using C, Zinc, D3+K2, N-Acetyl-Cysteine, melatonin and a glycyrrhizin extract. and eating an antisocial amount of garlic, onions, and leeks.


if nothing else I feel super healthy right now :lol:


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Offlinemorrowasted
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: morrowasted] * 3
    #26564332 - 03/28/20 11:30 PM (3 years, 10 months ago)

all of the goddamn science podcasts are talking about the same shit now


we get it, coronavirus is bad.


tell me something neat about dinosaurs or something :sad:

I swear I have barely been sleeping at all these days but not tired. cortisol must be going. stressed. not good for immune function :huxleyfacepalm:




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InvisibleballsalsaMDiscord
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: morrowasted] * 1
    #26564364 - 03/29/20 12:07 AM (3 years, 10 months ago)

bacopa, ashwagandha and magnesium to lower cortisol

also, look into pelargonium sidoides(for virus, not cortisol)


--------------------


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Invisiblecannabinated
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: ballsalsa]
    #26564365 - 03/29/20 12:10 AM (3 years, 10 months ago)

The one silver lining to this, so far, is that you can wear face shields now in public without being scolded


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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: cannabinated] * 1
    #26564388 - 03/29/20 12:33 AM (3 years, 10 months ago)

no that still looks ridiculous


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Invisiblecannabinated
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods]
    #26564391 - 03/29/20 12:37 AM (3 years, 10 months ago)

i already sank all my money into an order of face shields

back me up


theyre fasionable


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Invisiblecannabinated
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: cannabinated]
    #26564398 - 03/29/20 12:42 AM (3 years, 10 months ago)

a large portion of new yorkers are italian i wonder if genetics be playing a role again


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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: cannabinated]
    #26564411 - 03/29/20 01:07 AM (3 years, 10 months ago)

There may be something to that 🤷‍♂️


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods] * 1
    #26564447 - 03/29/20 02:15 AM (3 years, 10 months ago)

This video has a lot of insight into mitigation strategies based on computer modeling the epidemic.

Some upshots:

once the epidemic is widespread, travel bans are useless except in the case of cities with very few cases, isolation from the rest of the country might work.

Hygiene, maintaining proper distance, cleaning surfaces and not touching your face are the single most effective way to slow the rate of spread. Limiting the people you have contact with (social distancing) only works well if there’s is a high compliance rate, and reducing the number and amount time spent going to stores and other places where many random people gather, is effective but not as important as social distancing.

Key take away: Half assed stay at home orders are almost pointless. You need to just mandate stay at home isolation for a few weeks until new cases nearly dry up.

Once the number of cases is manageable and stable, widespread testing and mandatory isolation of those infected and their contacts will be required until either a large percentage of the population acquiress immunity. During this phase life can return to a fairly normal routine, aside for the immediate quarantine of the infected and their contacts.



Edited by koods (03/29/20 02:22 AM)


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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods]
    #26564464 - 03/29/20 02:53 AM (3 years, 10 months ago)

All about exponential growth



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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods]
    #26564488 - 03/29/20 03:58 AM (3 years, 10 months ago)

This is truly disturbing. Even the nature and existence of a pandemic is a political position now.



This one tweet was flooded with comments like these



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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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InvisibleShroomerInTheRye
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods]
    #26564576 - 03/29/20 06:27 AM (3 years, 10 months ago)

Last night right before I passed out, there were half as many recoveries as deaths in the USA according to the Johns Hopkins map.  This morning, there's more recoveries than deaths.  This is super great news, but what happened with the numbers there?


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InvisibleAsante
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: ShroomerInTheRye]
    #26564582 - 03/29/20 06:30 AM (3 years, 10 months ago)

Time passed.

Dead people have a faster recovery time (they die halfway through the disease) than recovered patients (who are only healed at the end of the disease.)


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