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CidAndShrooms
AcidAndShrooms

Registered: 03/14/20
Posts: 5
Loc: United States
Last seen: 3 years, 10 months
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Tripping 1
#26535457 - 03/14/20 08:04 PM (3 years, 10 months ago) |
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So I’m gonna be taking shrooms for the 2nd time tonight but it’ll be the first time since I started taking an SSRI(I’ve already checked for a dangerous interaction and there isn’t one so don’t mention it) and I was wondering if it’ll have a synergistic effect or a antagonist effect.
Edited by CidAndShrooms (03/14/20 08:05 PM)
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Shr00mEater
Strange


Registered: 10/17/18
Posts: 985
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If you say it isn’t dangerous, take the same amount you took last time and find out?
It seems like different people and different meds have different responses.
It will either be no different than before the meds, or you will need a lot more than usual. Meds never seem to make shrooms stronger. The exception being MAOIs.
Do a search on it, or, if you have the name of your specific SSRI someone else might also, and be able to give you their anecdotal reports.
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CidAndShrooms
AcidAndShrooms

Registered: 03/14/20
Posts: 5
Loc: United States
Last seen: 3 years, 10 months
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It’s sertraline probably should’ve mentioned that. I noticed that alcohol is much stronger so far.
-------------------- Total Trips : 2 LSD : 1 Mushrooms : 1 “I swear I’m not an alcoholic, I just like it.” - Me
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DJ Ed
Mushroom Engineer


Registered: 09/04/16
Posts: 2,326
Loc: UK
Last seen: 2 months, 15 days
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Unless you’re very lucky, sertraline will block the 5ht-2a receptors , ie the same ones psilocin works on. You may need twice the dose, or you may not trip at all, or you may trip. Toss of a coin dude, until you try. But as you say, not dangerous.
-------------------- “It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.” Michael Pollan: How To Change Your Mind “The problem is not to find the answer, it’s to face the answer.” Terence McKenna

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openmind
curious


Registered: 08/03/07
Posts: 13,876
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Quote:
CidAndShrooms said: So I’m gonna be taking shrooms for the 2nd time tonight but it’ll be the first time since I started taking an SSRI(I’ve already checked for a dangerous interaction and there isn’t one so don’t mention it) and I was wondering if it’ll have a synergistic effect or a antagonist effect.

SSRIs will block the effects of psychedelics.
Some folks claim they can still trip while on a SSRI but most folks only experience mild effects or nothing at all, and/or they need to take a large dose and they still don't experience the full spectrum of the experience & full potential of the dose.
If you want to work with mushrooms/psychedelics, you'll have to stop taking the SSRI.
My 2 cents...SSRIs are total garbage, not very helpful in the long run, and most people that are prescribed them shouldn't be on them. SSRIs block the effects of psychedelics which can actually help one work on their own issues/depression. I absolutely despise SSRIs, it's ridiculous how over prescribed they are and how many people are on them these days.
-OM
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Pandemoon
Ἧeẍeᾐmeḭsṫeŗ ͛


Registered: 01/28/14
Posts: 5,845
Loc: Europe
Last seen: 18 hours, 4 minutes
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What they said.
SSRIs block (or dull) any psychedelic effects. You will need a much higher dose than last time to get any effects.
You are going to take those two tiny shrooms shown in the picture? That's no real dose, man. It looks like less than a gram, which is like a quarter dose for people without medication.
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CidAndShrooms
AcidAndShrooms

Registered: 03/14/20
Posts: 5
Loc: United States
Last seen: 3 years, 10 months
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I weighed it and it came out to like 1.3 or 1.4. When I tripped on acid I had a 250ug tab that had definitely lost a good amount of it’s potency yet I still had complete ego loss and depersonalization and all that shit. Probably helps to mention I’m around 6’-6’1 and I weigh only like 130 or 140. Also I only take a 50mg Zoloft
-------------------- Total Trips : 2 LSD : 1 Mushrooms : 1 “I swear I’m not an alcoholic, I just like it.” - Me
Edited by CidAndShrooms (03/15/20 07:01 PM)
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