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PocketLady



Registered: 01/18/10
Posts: 1,773
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Re: Viral outbreak in China [Re: koods] 2
#26532801 - 03/13/20 01:51 PM (3 years, 10 months ago) |
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All of the big grocery stores in the nearest big town to me have completely bare shelves. If you don’t have food, please try and get some
-------------------- Love is from the infinite, and will remain until eternity. The seeker of love escapes the chains of birth and death. Tomorrow, when resurrection comes, The heart that is not in love will fail the test. ~ Rumi The day we start giving Love instead of seeking Love, we will have re-written our whole destiny. ~ Swami Chinmayanada Saraswatir
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Asante
Mage


Registered: 02/06/02
Posts: 86,795
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Re: Viral outbreak in China [Re: koods] 1
#26532808 - 03/13/20 01:56 PM (3 years, 10 months ago) |
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-------------------- Omnicyclion.org higher knowledge starts here
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Niffla



Registered: 06/09/08
Posts: 46,482
Loc: Texas
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Re: Viral outbreak in China [Re: PocketLady] 1
#26532811 - 03/13/20 01:58 PM (3 years, 10 months ago) |
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Quote:
PocketLady said: All of the big grocery stores in the nearest big town to me have completely bare shelves. If you don’t have food, please try and get some 
I got really just a minimal amount -- should've got more, but I should be good for a couple of weeks give or take. I'm wondering if waiting it out for the carnage that will take place this weekend, which will be on an epic scale -- and then going very early on Monday morning (like 6 am early) would work...assuming the stockers do well in replenishing the shelves on Sunday night.
I did go yesterday and today and filled the trunk both times
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HAIL OUR NEW OTD KING
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InfiniteDreams


Registered: 10/25/19
Posts: 1,224
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Re: Viral outbreak in China [Re: Asante]
#26532813 - 03/13/20 01:59 PM (3 years, 10 months ago) |
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We're all gonna die. If I can't buy food cause the supply chain breaks down, did I starve to death due to coronavirus?
Also, my neighbor's barking dogs are looking more edible by the hour.
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koods
Ribbit



Registered: 05/26/11
Posts: 106,049
Loc: Maryland/DC Burbs
Last seen: 4 hours, 6 minutes
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Re: Viral outbreak in China [Re: hummingbird] 2
#26532818 - 03/13/20 02:01 PM (3 years, 10 months ago) |
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Quote:
hummingbird said:
Quote:
koods said: Immunity is based on the amino acid sequence in the protein coating. You don’t know what you’re talking about
Take it how you want, but many more people are recovering than dying...which obviously hints at some kind of immunity.
Yes it is acquired immunity. When you get exposed to the virus you have an immune response. Antibodies are developed. Antibodies are proteins that attach to the virus then the immune system attacks those antibodies which kills the virus. Until you are exposed to the virus you have no acquired immunity and since this is a virus that evolved outside the human population there is likely no acquired immunity to any similar viruses. Now there is likely a small amount of the population who have an inate genetic immunity becasue the cells in their body have mutations that prevent the virus from attaching to and infecting these cells. It’s all about the amino acid sequences.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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koods
Ribbit



Registered: 05/26/11
Posts: 106,049
Loc: Maryland/DC Burbs
Last seen: 4 hours, 6 minutes
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Re: Viral outbreak in China [Re: koods] 4
#26532829 - 03/13/20 02:09 PM (3 years, 10 months ago) |
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Vaccines are essentially non infectious versions of viral protein coatings. Antibodies are created in the same manner as an actual infection. Once you have developed acquired immunity through exposure or vaccine, a virus with that protein coating or similar protein coating will immediately be attacked and deactivated by antibodies before causing infection.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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psi
TOAST N' JAM


Registered: 09/05/99
Posts: 31,456
Loc: 613
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I was under the impression that mutations happened more or less instantaneously. A single base pair changes due to a replication error and then that codon (often) codes for a different amino acid, perhaps resulting in an amino acid sequence never seen before by anyone's immune system. But does the immune system detect these proteins on the level of analyzing the exact sequence of amino acids (keeping in mind that the protein is no longer jut a chain but has folded into a tertiary structure), or is it more of a macro level thing of their overall chemical properties? My impression is that it is the latter, and that never having seen a protein with some exact sequence of amino acids before is the norm with any boring seasonal virus.
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audiophoenix
Find Peace


Registered: 08/28/09
Posts: 4,107
Loc: Upstate NY
Last seen: 2 years, 8 months
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Re: Viral outbreak in China [Re: koods] 1
#26532836 - 03/13/20 02:14 PM (3 years, 10 months ago) |
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Predicted cases vs what the actual number was and predictions going forward.
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spirit_shadow
Feature not a bug



Registered: 08/15/11
Posts: 25,665
Last seen: 25 minutes, 2 seconds
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Re: Viral outbreak in China [Re: koods]
#26532840 - 03/13/20 02:18 PM (3 years, 10 months ago) |
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Quote:
koods said: There’s no data showing firearms are effective against viruses
I'm pretty sure if used against everyone that has the virus it would be 100% effective
-------------------- ERROR 418 IM A TEAPOT.....(this account is automated, all posts related to illegal activities or advice thereof are strictly from numerous online sites and are for informational purposes only)- Circa 2011 Ban lotto
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koods
Ribbit



Registered: 05/26/11
Posts: 106,049
Loc: Maryland/DC Burbs
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Re: Viral outbreak in China [Re: psi]
#26532841 - 03/13/20 02:18 PM (3 years, 10 months ago) |
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It all has to do with the theee dimensional shape of the protein. Minor changes in genetic sequence may not change the shape of the protein significantly. It’s also important to understand that a significant change in the protein coating will almost always render a virus non infectious since it can only infect a cell if it fits into the receptors on the cell.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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Asante
Mage


Registered: 02/06/02
Posts: 86,795
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Re: Viral outbreak in China [Re: koods] 2
#26532847 - 03/13/20 02:22 PM (3 years, 10 months ago) |
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I missed a word there in Trump's speech.
The tests will be there
FAST IN GREAT NUMBERS IN MANY LOCATIONS
I didnt catch him saying that they would be FREE like they are in the rest of the world.
-------------------- Omnicyclion.org higher knowledge starts here
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audiophoenix
Find Peace


Registered: 08/28/09
Posts: 4,107
Loc: Upstate NY
Last seen: 2 years, 8 months
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Re: Viral outbreak in China [Re: Asante] 2
#26532852 - 03/13/20 02:23 PM (3 years, 10 months ago) |
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I guess I didn't listen for that. I would think they have to be or else it won't be effective.
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koods
Ribbit



Registered: 05/26/11
Posts: 106,049
Loc: Maryland/DC Burbs
Last seen: 4 hours, 6 minutes
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Re: Viral outbreak in China [Re: koods] 1
#26532854 - 03/13/20 02:24 PM (3 years, 10 months ago) |
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The human population is exposed to billions of novel viruses from animals all the time. A huge majority (like 99.999999%) are non infectious because their protein coatings do not fit into the receptors coating human cells. This virus had simply evolved a protein through random mutations within an animal population that allowed it to infect human cells. And it took off. It was probably one animal that had a minor infection that infected a single human and that human had an infection that allowed the virus to replicate and spread to other people.
The reason this virus is dangerous is because it evolved to be infectious to humans within an animal population. For the most part, flu viruses evolve within the human population so it is hard for this evolution to drift away from the acquired immunity within a human population. The dangerous flus often jump from people back to animals and then back to humans again. They get to evolve away from humans for more time than other flus but they are still not completely novel.
What is important to remember is as a virus mutates WITHIN a human population, most of these mutations will render that virus less infectious faster than it will get around acquired immunity. It really takes a radical jump to get more infectious while defeating acquired immunity. It really takes evolution OUTSIDE a human population to both be highly infectious and be without any human immunity.
Edited by koods (03/13/20 02:37 PM)
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koods
Ribbit



Registered: 05/26/11
Posts: 106,049
Loc: Maryland/DC Burbs
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Re: Viral outbreak in China [Re: koods] 1
#26532888 - 03/13/20 02:45 PM (3 years, 10 months ago) |
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I should also point out that successful acquired immunity within an individual almost always requires that person to get exposed to billions of copies of a virus. So we arent taking about exposure that is defeated by the naive immune system that attacks unknown microbes. People can get exposed to a virus and not develop immunity. It generally requires that virus to replicate within the body, or in the case of a vaccine, enough particles to imitate an actual infection. That’s why people can feel slightly sick after a vaccine. The body THINKS there is an actual infection when in reality you have just been flooded with non infectious particles that the body thinks are due to an infection.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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Tripsurfer
Bring Back Asante!



Registered: 08/01/12
Posts: 7,129
Loc: West of Windward
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Re: Viral outbreak in China [Re: koods]
#26532899 - 03/13/20 02:50 PM (3 years, 10 months ago) |
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My local supermarket 20 minutes ago
-------------------- Ach en wee ben ik de klos, met mijn boog schoot ik een albatros... A philosopher is a person who knows less and less about more and more, until he knows nothing about everything.

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audiophoenix
Find Peace


Registered: 08/28/09
Posts: 4,107
Loc: Upstate NY
Last seen: 2 years, 8 months
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Re: Viral outbreak in China [Re: Tripsurfer]
#26532900 - 03/13/20 02:51 PM (3 years, 10 months ago) |
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Quote:
Tripsurfer said:

My local supermarket 20 minutes ago
NYS has the most cases, and our stores are able to keep up. I don't get it.
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Tripsurfer
Bring Back Asante!



Registered: 08/01/12
Posts: 7,129
Loc: West of Windward
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Here everybody panicked today. Our PM told people not to hoard. This obviously triggered massive hoarding
-------------------- Ach en wee ben ik de klos, met mijn boog schoot ik een albatros... A philosopher is a person who knows less and less about more and more, until he knows nothing about everything.

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audiophoenix
Find Peace


Registered: 08/28/09
Posts: 4,107
Loc: Upstate NY
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Re: Viral outbreak in China [Re: Tripsurfer] 1
#26532909 - 03/13/20 02:55 PM (3 years, 10 months ago) |
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Quote:
Tripsurfer said: Here everybody panicked today. Our PM told people not to hoard. This obviously triggered massive hoarding 
Oh I didn't realize you were overseas. But I've seen similar pics from down south.
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InfiniteDreams


Registered: 10/25/19
Posts: 1,224
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Re: Viral outbreak in China [Re: Tripsurfer]
#26532915 - 03/13/20 03:00 PM (3 years, 10 months ago) |
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Quote:
Tripsurfer said:

My local supermarket 20 minutes ago
So coronavirus does cause disintegration!
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koods
Ribbit



Registered: 05/26/11
Posts: 106,049
Loc: Maryland/DC Burbs
Last seen: 4 hours, 6 minutes
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trump shook everyone’s hands at the end of the news conference despite the fact that his own government recommendations state he should be in self quarantine due to his exposure to confirmed cases. It’s really hard to understate how stupid he is.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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