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Guy1980
Registered: 09/11/12
Posts: 723
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Re: Viral outbreak in China - COVID 19 aka. SARS-CoV-2 aka Wuhan Coronavirus [Re: pslyke]
#26575122 - 04/03/20 11:45 AM (3 years, 9 months ago) |
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I plotted the numbers for the UK (deaths Vs cases confirmed 14 days prior). It's not a lot of data to go on I admit, but after an initial period where the small samples skew the data, the correlation is pretty strong.

So I naturally did the same for the US. The correlation is there, but the two plots diverge about 4 days prior (18 days prior for testing).

Either the testing of positives ramped up 14 days ago, or the US has staved off a few deaths/delayed/under reported them. Looking forwards, I'd expect a big jump in deaths (versus deaths 10 days prior) before the US starts moving in the right direction.

Either way, both countries are infecting at a rate of higher than 1, so this situation isn't improving massively. Hopefully we'll all be able to stay below capacity of the healthcare systems.
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koods
Ribbit



Registered: 05/26/11
Posts: 106,049
Loc: Maryland/DC Burbs
Last seen: 7 minutes, 59 seconds
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Re: Viral outbreak in China [COVID 19 aka. SARS-CoV-2 aka "Wuhan Coronavirus"] [Re: Guy1980]
#26575138 - 04/03/20 11:53 AM (3 years, 9 months ago) |
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Chris Cuomo “the beast comes out at night”
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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morrowasted
Worldwide Stepper


Registered: 10/30/09
Posts: 31,377
Loc: House of Mirrors
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Re: Viral outbreak in China [COVID 19 aka. SARS-CoV-2 aka "Wuhan Coronavirus"] [Re: koods] 5
#26575166 - 04/03/20 12:06 PM (3 years, 9 months ago) |
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qman
Stranger

Registered: 12/06/06
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Re: Viral outbreak in China [COVID 19 aka. SARS-CoV-2 aka "Wuhan Coronavirus"] [Re: morrowasted]
#26575182 - 04/03/20 12:15 PM (3 years, 9 months ago) |
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Guy1980
Registered: 09/11/12
Posts: 723
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Re: Viral outbreak in China [COVID 19 aka. SARS-CoV-2 aka "Wuhan Coronavirus"] [Re: morrowasted]
#26575188 - 04/03/20 12:24 PM (3 years, 9 months ago) |
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Quote:
morrowasted said:
Wish me luck
Good luck champ, this is good work you're doing
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Herbologist
Grrratata



Registered: 05/09/10
Posts: 7,471
Loc: Casa Bonita
Last seen: 3 years, 1 month
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: qman] 1
#26575197 - 04/03/20 12:29 PM (3 years, 9 months ago) |
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Is there any evidence that UV light will kill covid-19?
Wondering if a cordless UV light would be beneficial if sanitizing items are running low.
-------------------- Shroomery Law: Don't piss off the leftist mods & their friends!
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falcon



Registered: 04/01/02
Posts: 8,005
Last seen: 3 hours, 10 minutes
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: Herbologist]
#26575237 - 04/03/20 01:10 PM (3 years, 9 months ago) |
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I read somewhere it's a specific wavelength and it's time consuming, the light has to be on the surface for a while. They are using UV robots to sanitize some hospital surfaces. Can't find a good link right now.
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morrowasted
Worldwide Stepper


Registered: 10/30/09
Posts: 31,377
Loc: House of Mirrors
Last seen: 3 days, 23 hours
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: Herbologist] 5
#26575242 - 04/03/20 01:16 PM (3 years, 9 months ago) |
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https://www.sciencedirect.com/science/article/pii/S0024320520303313
COVID-19: Melatonin as a potential adjuvant treatment
This article summarizes the likely benefits of melatonin in the attenuation of COVID-19 based on its putative pathogenesis. The recent outbreak of COVID-19 has become a pandemic with tens of thousands of infected patients. Based on clinical features, pathology, the pathogenesis of acute respiratory disorder induced by either highly homogenous coronaviruses or other pathogens, the evidence suggests that excessive inflammation, oxidation, and an exaggerated immune response very likely contribute to COVID-19 pathology. This leads to a cytokine storm and subsequent progression to acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) and often death. Melatonin, a well-known anti-inflammatory and anti-oxidative molecule, is protective against ALI/ARDS caused by viral and other pathogens. Melatonin is effective in critical care patients by reducing vessel permeability, anxiety, sedation use, and improving sleeping quality, which might also be beneficial for better clinical outcomes for COVID-19 patients. Notably, melatonin has a high safety profile. There is significant data showing that melatonin limits virus-related diseases and would also likely be beneficial in COVID-19 patients. Additional experiments and clinical studies are required to confirm this speculation.
This putative “cytokine storm” pathology associated with coronaviruses is also supported by experimental SARS-CoV models, one of which showed that the severity of ALI was accompanied by an elevated expression of inflammation-related genes rather than increased viral titers. In another case, the ablation of IFN-α/β receptor or the depletion of inflammatory monocytes/macrophages caused a marked rise in the survival rate of coronaviruses host without a change in viral load [19,20]. Both situations suggest a potential amplifying mechanism involved in CoV-induced ALI/ARDS regardless of the viral load. If a similar pathology also exists in COVID-19, the attenuation of the cytokine storm by targeting several key steps in the process could bring about improved outcomes.
Melatonin is not viricidal but it has indirect anti-viral actions [3] due to its anti-inflammation, anti-oxidation and immune enhancing features [[21], [22], [23], [24]]. There are situations in which melatonin suppresses the features of viral infections. In mice whose central nervous system is infected by virus (e.g., encephalitis), the use of melatonin caused less viremia, reduced paralysis and death, and decreased virus load [25]. In previous respiratory syncytial virus models, melatonin caused down-regulation of acute lung oxidative injury, pro-inflammatory cytokine release and inflammatory cell recruitment. These findings, along with those recently summarized by Reiter et al. [3], support a rationale for melatonin use in viral diseases. Also, melatonin's anti-inflammation, anti-oxidation, immune enhancing actions supports its potential attenuation of COVID-19 infection (Fig. 1)...
The anti-inflammatory effect of melatonin involves the suppression of NF-κB activation in ARDS [28,29]. Melatonin reportedly down-regulate NF-κB activation in T cells and lung tissue [30,31]. The stimulation of NF-E2-related factor 2 (Nrf2) is crucial in protecting lung from injury. In related studies, melatonin induces the up-regulation of Nrf2 with therapeutic effects in hepatoprotection, cardioprotection, etc. [32]. Whether Nrf2 is involved in the CoV-induced ALI remains unknown, but the close interaction of SIRT1, NF-κB and Nrf2 suggests their participation in the CoV-induced ALI/ARDS. As such, the data support the potential anti-inflammatory action of melatonin. Inflammation is commonly associated with an elevated production of cytokines and chemokines, while melatonin causes a reduction in the pro-inflammatory cytokines. TNF-α, IL-1β, IL-6, and IL-8, and an elevation in the level of anti-inflammatory cytokine IL-10 [33,34]. There may be, however, some concerns about the potential pro-inflammatory actions of melatonin when used in very high doses or under suppressed immune conditions where it may induce an increase production of pro-inflammatory cytokines, IL-1β, IL-2, IL-6, IL-12, TNF-α, and IFN-γ [35]. Conversely, in ALI infection models, melatonin presents with anti-inflammatory and protective action [6]....
In a randomized controlled trial, 8-week oral intake of 6 mg/d melatonin caused a significant decrease in serum levels of IL-6, TNF-α and hs-C-reactive protein (hs-CRP) in patients with diabetes mellitus and periodontitis [56]. In another trial of patients suffering with severe multiple sclerosis, orally 25 mg/d of melatonin for 6 months also promoted a significant reduction in serum concentrations of TNF-α, IL-6, IL-1β and lipoperoxides [57]. In the acute phase of inflammation, including during surgical stress [58], brain reperfusion [59], and coronary artery reperfusion [60], melatonin intake of 10 mg/d, 6 mg/d and 5 mg/d of melatonin for less than 5 days induced a reduced level of pro-inflammatory cytokines. A recent meta-analysis of a total of 22 randomized controlled trials suggested that a supplementary use of melatonin is associated with a significant reduction of TNF-α and IL-6 level [61]. This clinical evidence suggests that the use of melatonin as a supplement may effectively reduce the levels of circulating cytokines, and may potentially also lower pro-inflammatory cytokine levels in COVID-19 patients.
I personally wouldn't go downing large doses of melatonin prophylatically. I take small doses (750mcg), and if I get sick and develop shortness of breath, I intend to switch to large doses (5-10mg).
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feevers


Registered: 12/28/10
Posts: 8,546
Loc:
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: falcon] 2
#26575249 - 04/03/20 01:25 PM (3 years, 9 months ago) |
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Mass's governor Baker was told by Trump that states should find their own ways to procure medical equipment. Baker then ordered millions of n95 masks through a private seller (like he was told), and the federal government seized them before the shipment reached MA along with repeatedly cancelling other orders.
He had to resort to getting the New England Patriots owner to fly the team jet to China and literally fill it with masks to bring home, some of which he's distributing to NYC and RI.
This shit is getting dystopian.
Quote:
At his daily press conference today, Gov. Baker said he managed to keep all those Chinese N95 masks out of federal hands by calling their shipment a "private humanitarian mission" and enlisting the help of the Kraft family, who sent their football team's jet over to China to pick them up.
Meanwhile, state officials said Massachusetts has yet to receive any of the 1,000 ventilators the feds had earlier promised Baker Massachusetts would get.
https://www.universalhub.com/2020/baker-got-krafts-involved-getting-those-masks-try
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tyrannicalrex
Strange R



Registered: 04/24/03
Posts: 38,323
Loc: subtropics
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: feevers] 1
#26575274 - 04/03/20 01:48 PM (3 years, 9 months ago) |
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Rich people profit with money, goods, and everything else as usual.
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Ovoidhunter
Buttery Crescent



Registered: 09/17/16
Posts: 2,016
Last seen: 2 years, 8 months
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: tyrannicalrex] 1
#26575358 - 04/03/20 02:51 PM (3 years, 9 months ago) |
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I know this is a little bit off topic but this is a big debate in my area right now. I grow cannabis ever year and usually the national guards eradication teams get about half of my crop. Do you guys think that they will be funded this year with the Covid-19 and all?
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InfiniteDreams


Registered: 10/25/19
Posts: 1,224
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: Ovoidhunter]
#26575387 - 04/03/20 03:10 PM (3 years, 9 months ago) |
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Thank you COVID-19 for preserving cannabis plantations!!!
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Ovoidhunter
Buttery Crescent



Registered: 09/17/16
Posts: 2,016
Last seen: 2 years, 8 months
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: InfiniteDreams] 1
#26575414 - 04/03/20 03:27 PM (3 years, 9 months ago) |
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I'll jump for joy if covid-19 means I get a full crop in this year I don't care. Would be a perk for me since I live out in the country in one of the least hard hit places. Obviously I'm not celebrating all the death and shit.. 
Just tryna make a small living like everyone else.
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deucedbi9
Stranger

Registered: 10/24/06
Posts: 4,594
Loc: UK
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Re: Viral outbreak in China [COVID 19 aka. SARS-CoV-2 aka "Wuhan Coronavirus"] [Re: morrowasted]
#26575421 - 04/03/20 03:31 PM (3 years, 9 months ago) |
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Quote:
morrowasted said: The covid pts are starting to roll in here in houston
https://www.nbcnews.com/news/us-news/houston-hasn-t-reported-surge-coronavirus-cases-its-hospitals-tell-n1175291
Wish me luck
I wondered if your previously reported low Covid count was due to a higher than usual 'all American, independent of Government' type of ethic among the people in the southern states.
Turns out that 7/10 least insured (and assuming this list refers to medically uninsured) are in Texas:
the 10 large cities with the highest uninsured rates based on the analysis:
1. Dallas
2. Houston
3. El Paso, Texas
4. Miami
5. Fort Worth, Texas
6. Arlington, Texas
7. Corpus Christi, Texas
8. San Antonio
9. Tulsa, Okla.
10. Oklahoma City
https://www.beckershospitalreview.com/rankings-and-ratings/10-major-cities-with-the-highest-lowest-uninsured-rates-110419.html
Matbe it was just a matter of time before the shit hit the fan.
Good luck out there Morrow'. We're rooting for ya.
-------------------- whether low pressure sucks or high pressure blows... it's a bugger to cycle in. even though I'm feeling good Something tells me I'd better activate my prayer capsule
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larry.fisherman
shoulda died already


Registered: 11/03/12
Posts: 36,294
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: deucedbi9] 1
#26575425 - 04/03/20 03:32 PM (3 years, 9 months ago) |
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To my fellow Canadians, a petition about rent relief with almost 800,000 signatures.
http://chng.it/NqzRBXY5Jy
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koods
Ribbit



Registered: 05/26/11
Posts: 106,049
Loc: Maryland/DC Burbs
Last seen: 7 minutes, 59 seconds
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: larry.fisherman]
#26575432 - 04/03/20 03:36 PM (3 years, 9 months ago) |
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800,000 is twice the population 🤪
--------------------
NotSheekle said “if I believed she was 16 I would become unattracted to her”
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larry.fisherman
shoulda died already


Registered: 11/03/12
Posts: 36,294
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods] 3
#26575448 - 04/03/20 03:41 PM (3 years, 9 months ago) |
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morrowasted
Worldwide Stepper


Registered: 10/30/09
Posts: 31,377
Loc: House of Mirrors
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods]
#26575457 - 04/03/20 03:44 PM (3 years, 9 months ago) |
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It's largely cuz texas doesnt accept federal medicare funds for a lot of people that other states do.
You cant be denied emergency treatment on the basis of lack of insurance. If you show up to the ER in respiratory distress from COVID you will get admitted, insurance or no. A lot of people think they have to go to the public hospitals but they don't. Take your ass to the nicest ER in town. Yeah you may end up with a bill that leaves ya bankrupt but... you'll live.
Maybe some uninsured texans are avoiding the hospital because theyre afraid of being deported or ending up with a massive bill though.
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sh4d0ws
LSx


Registered: 02/26/08
Posts: 12,086
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: morrowasted]
#26575471 - 04/03/20 03:53 PM (3 years, 9 months ago) |
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I bet all the melatonin will be sold out soon, gone like toilet paper
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LogicaL Chaos
Ascension Energy & Alien UFOs




Registered: 05/12/07
Posts: 69,333
Loc: The Inexpressible...
Last seen: 30 minutes, 23 seconds
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Re: Viral outbreak in China - COVID 19 aka. SARS-CoV-2 aka Wuhan Coronavirus [Re: pslyke]
#26575475 - 04/03/20 03:55 PM (3 years, 9 months ago) |
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Quote:
pslyke said: What do my shroomy friends in the US think about the fact that Trump has prohibited 3M from shipping masks to Canada. Do you support such a decision, or do you think resources should be shared in a bilateral way?
I despise anything Trump says or does. I hate the guy. But, the US is in a crisis amd we are short on masks, so i guess it makes sense to not export. I dunno....its all fucked up either way.
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