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Offlinechibiabos
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: psi]
    #26557451 - 03/25/20 05:01 PM (3 years, 9 months ago)

Quote:

psi said:
Quote:

chibiabos said:
Quote:

LeningradCowboy said:
https://nextstrain.org/ncov

known mutations of SARS-NCoV-2

Asante or Morrowasted or somebody with knowledge about these kind things please translate this in english.



They're basically comparing genomes of novel coronaviruses causing covid-19 in order to figure out how similar they are to each other.  You'd expect mutants, because that just how things work, but aside from figuring out how quickly certain genes mutate they can also figure out which mutants are most likely to have evolved directly from which ancestor and construct the phylogeny that you see (which helps them figure out how the virus has been spreading).



Cool site.



https://rosalind.info has some neat projects that let you dip your toe into the field a little bit.


Edited by chibiabos (03/25/20 05:08 PM)


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OfflineLeningradCowboy
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: chibiabos]
    #26557457 - 03/25/20 05:04 PM (3 years, 9 months ago)

Thank you chibiabos!


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Offlinechibiabos
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: morrowasted]
    #26557462 - 03/25/20 05:07 PM (3 years, 9 months ago)

Quote:

morrowasted said:
Quote:

chibiabos said:
Quote:

morrowasted said:
Just heard the infectious disease guy on MSNBC admit this will probably be seasonally and geographically variable for the first time



Could be, but those sort of predictions are more or less contingent on the bleeding edge of science and the data is changing day by day (if not more often).


feel free to share a single study suggesting this does not vary seasonally and geographically



Just because I'm not validating your statement it doesn't mean that I'm arguing with you.  There's a lot that's unknown and all that any experts in any aspect of this crisis can do is work with a rapidly changing body of knowledge.  Nobody's going to be able to give you definitive statements about this crisis because their knowledge has limits.  They'll do their best to communicate what they do know, but what they know is also changing very rapidly.  At this point all that they can really tell you with any certainty is to stay home and do your best to avoid transmitting this thing, in large part because they need to catch up with the outbreak and figure out how to get it under control.


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Offlinemorrowasted
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: chibiabos]
    #26557471 - 03/25/20 05:09 PM (3 years, 9 months ago)

They just projected that houston cases would have been about 10x as high had social distance measure not been taken. Guy on TV said they are predicting a total of about 1200 cases this year in Houston based on current models


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Offlinemorrowasted
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: chibiabos]
    #26557475 - 03/25/20 05:12 PM (3 years, 9 months ago)

Not arguing that we ought to change recommendations about social distancing just yet. Just being realistic. If anyone is in a position to be seriously worried about this,it's me. Dont mean to sound like a jackass but er workers tend to be the most exposed to endemic diseases


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Invisiblepsi
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: chibiabos] * 3
    #26557481 - 03/25/20 05:17 PM (3 years, 9 months ago)

Quote:

chibiabos said:
http://rosalind.info has some neat projects that let you dip your toe into the field a little bit.




Was unable to connect until I changed the https to http, looks cool though. A lot of my programming background is with python.


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InvisibleballsalsaMDiscord
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: psi] * 1
    #26557502 - 03/25/20 05:42 PM (3 years, 9 months ago)

Italy reporting 683 deaths today, a significant 1 day decline if it holds.
over the last 4 days, deaths in italy declined 2 in a row, spiked for a day and declined again for a day.  The next few days will tell us a lot about how the virus is likely to play out in the states that responded more like italy.


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Offlinemorrowasted
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: psi]
    #26557508 - 03/25/20 05:46 PM (3 years, 9 months ago)

I'm seeing a lot of nurses saying they had pts with s&s of covid but negative influenza since beginning of last November. If it turns out that this was lurking around disguised as an unknown resp. Illness for a couple months then we would have to assume that either the series interval is even higher presently estimated or the global r0 is lower than estimated


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InvisibleInfiniteDreams
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: morrowasted] * 2
    #26557566 - 03/25/20 06:09 PM (3 years, 9 months ago)

Quote:

morrowasted said:
I'm seeing a lot of nurses saying they had pts with s&s of covid but negative influenza since beginning of last November. If it turns out that this was lurking around disguised as an unknown resp. Illness for a couple months then we would have to assume that either the series interval is even higher presently estimated or the global r0 is lower than estimated




I have anecdotes that support this.  Likely this has been around longer than supposed and just took time to work its way into the fragile.

Regarding the Spanish flu we love to compare to, which caused an epidemic in 1918:

Quote:

In addition, the haemagglutinin glycoproteins of the virus suggest that it was around far prior to 1918 and other studies suggest that the reassortment of the H1N1 virus likely occurred in or around 1915.




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Invisibletrees
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: InfiniteDreams] * 4
    #26557570 - 03/25/20 06:12 PM (3 years, 9 months ago)

Look at this doctor guy talking about intraveinous 1500mg vitamin C In NYC hospitals for Corona

https://nypost.com/2020/03/24/new-york-hospitals-treating-coronavirus-patients-with-vitamin-c/amp/


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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: trees] * 3
    #26557602 - 03/25/20 06:29 PM (3 years, 9 months ago)

Quote:

trees said:
Look at this doctor guy talking about intraveinous 1500mg vitamin C In NYC hospitals for Corona

https://nypost.com/2020/03/24/new-york-hospitals-treating-coronavirus-patients-with-vitamin-c/amp/




Some docs in China did it too with apparent success

Never throw the baby out with the bathwater


I've been taking 3g vitamin c and 50mg zinc daily


Would be interested to do an autopsy on some of these athletes to see if they had low c levels. Some athletes eat a diet that is conducive to water soluble mineral deficiency

Also seeing some fairly convincing orthomelcular explanations for a connection between free heme and pathological macrophage activity in coronavirus infections


Edited by morrowasted (03/25/20 07:50 PM)


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OfflineLeningradCowboy
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: psi]
    #26557609 - 03/25/20 06:33 PM (3 years, 9 months ago)

Quote:

psi said:
Quote:

chibiabos said:
http://rosalind.info has some neat projects that let you dip your toe into the field a little bit.




Was unable to connect until I changed the https to http, looks cool though. A lot of my programming background is with python.




Same thing. the link just jumps to this thread.


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FREE HAMHEAD 2020!


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OfflineLeningradCowboy
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: LeningradCowboy]
    #26557614 - 03/25/20 06:37 PM (3 years, 9 months ago)

Same 1-2 g organically sourced C and zinc about 60-90mg day.
It´s nice to realize that my intuition was right about this one.

The amounts used in china in iv treatment are way higher than 1500mg. we are talking daily doses of 11000-21000mg.


--------------------
From tundra with love!


FREE HAMHEAD 2020!


Edited by LeningradCowboy (03/25/20 06:39 PM)


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InvisiblefeeversM
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: LeningradCowboy]
    #26557640 - 03/25/20 06:53 PM (3 years, 9 months ago)

Trump Wants To 'Reopen America.' Here's What Happens If We Do, In An Interactive Chart
https://www.nytimes.com/interactive/2020/03/25/opinion/coronavirus-trump-reopen-america.html


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Invisibletyrannicalrex
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: morrowasted] * 3
    #26557655 - 03/25/20 07:02 PM (3 years, 9 months ago)

You really paid attention in biology and microbiology!


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Offlinemorrowasted
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: tyrannicalrex] * 7
    #26557768 - 03/25/20 08:03 PM (3 years, 9 months ago)



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Invisiblepsi
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: morrowasted] * 1
    #26557774 - 03/25/20 08:05 PM (3 years, 9 months ago)

:meffz:


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OfflineSonicTitan
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: psi] * 1
    #26557821 - 03/25/20 08:30 PM (3 years, 9 months ago)

In 10 years they will make an overly dramatic movie about Corona virus. Michael Bay will direct it I bet.


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Offlinekoods
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: SonicTitan]
    #26557853 - 03/25/20 08:45 PM (3 years, 9 months ago)

We’re gonna be up to 100,000 cases and 2,000 deaths by Saturday


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InvisibleCrazy_Horse
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Re: Coronavirus 2020 aka Wuhan Coronavirus aka COVID-19 [Re: koods]
    #26557870 - 03/25/20 08:58 PM (3 years, 9 months ago)

That’s terrible.


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