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Amanita86
OTD Keymaster


Registered: 09/26/12
Posts: 89,464
Loc: hades
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Re: Kratom [Re: deadwk]
#26445090 - 01/21/20 07:45 PM (4 years, 7 days ago) |
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What is the proper ‘application’ of Loperimide’ when using it to counter opiate wd’s?
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Orange clock, pencil "They threw me off the hay truck about noon..."
*Mark 15:34  Gam zeh ya’avor...
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TheUltimateBohab
Fat and Slobby


Registered: 09/05/18
Posts: 319
Loc: LV-426
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Quote:
Amanita86 said: What is the proper ‘application’ of Loperimide’ when using it to counter opiate wd’s?
Yeah I was wondering that too I've never even heard of it....
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theRealrollforever
I DID-DENT



Registered: 08/31/13
Posts: 12,736
Loc: Bada-Bing!
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You take it so you aren’t chained 5 feet from a bathroom with the shits lol. It makes your digestive tract not be in knots and physically hurt.
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metalfaith
Moron



Registered: 03/30/11
Posts: 1,842
Loc: FL
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I started using kratom occasionally. Then regularly. The daily.
And you know, I knew it was an opioid, whereas you seem to he hiding that fact. Even knowing all that I still ended dependent. Took over a year, but it did happen.
Never had real opiate withdrawl but dang the insomnia makes it very difficult to quit. Who has 3-5 days to throw away?
With infrequent use, it is beautiful. If you lose diligence though, you will be dependent and not even catching a buzz.
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PatrickKn


Registered: 07/10/11
Posts: 20,562
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I had 300 grams last me about 2 years. I wouldn't take it too often though, and wouldn't usually take more than 2-5 grams. I'd almost never take it more than once in a week or two either. I think the key to managing anything is to follow similar patterns of moderate usage, but you're not always in the right mindset to do so either.
Had I discovered kratom when I was a teenager I'd probably be scarfing down ounces. Kratom is nice in small amounts though, and I would pack gel capsules by hand the day of dosing, seriously limiting my desire to even bother most of the time.
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deadwk
00101011


Registered: 06/17/09
Posts: 8,890
Loc: Canada, eh?
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So the issue with loperamide is that in large doses it can back you up, but in low doses it can alleviate symptoms of opiate withdrawal effects. It will not cure them, nor will it stop severe nausea but it will alleviate symptoms. In my case it would alleviate the clammy skin, and depending on the severity of the WD's it has reduced the dizzines a bit.
I'm not even sure there's 100% conclusive evidence about it, but there's a lot of anecdotal reports, so it could very well be real and unstudied, or placebo. You can search for the keyword `loperamide` on shroomery, google, and other drug forums and you will get a lot of results.
DYOR+YMMV. Taking too much loperamide will cause issues, and potentially death.
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deadwk
00101011


Registered: 06/17/09
Posts: 8,890
Loc: Canada, eh?
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Quote:
metalfaith said: I started using kratom occasionally. Then regularly. The daily.
And you know, I knew it was an opioid, whereas you seem to he hiding that fact. Even knowing all that I still ended dependent. Took over a year, but it did happen.
Never had real opiate withdrawl but dang the insomnia makes it very difficult to quit. Who has 3-5 days to throw away?
With infrequent use, it is beautiful. If you lose diligence though, you will be dependent and not even catching a buzz.
This 100%. I find it pretty easy to forgot that kratom really is an opiate, and you can get dependent on it just like any other opiate, albeit to a significantly less degre. One of the things I think that makes kratom WD's slightly different than typical opiates is that they also activate abunch of other receptors than your opiod ones, seratonin, dopamine, and perhaps norenepherine.
I have a sneaking suspicion that because of this, long-term use gets receptor dependency on more than just opiate receptors, mostly seratonin. When I took kratom every day for a year and stopped I got symptoms that felt like when I dont take my anti-depressants for a week and go into SSRI withdrawal.
Personally speaking once a month I'll grab some kratom on a friday, and spend the weekend getting kratted the fuck out. Seems to keep the magic there, and dependency at bay.
Edited by deadwk (01/22/20 10:48 PM)
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Amanita86
OTD Keymaster


Registered: 09/26/12
Posts: 89,464
Loc: hades
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Re: Kratom [Re: deadwk]
#26447370 - 01/22/20 11:29 PM (4 years, 6 days ago) |
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I’ve been reading up on it since you posted earlier and turns out it is an opioid, commonly sold as Immodium.
From Wikipedia: It is an opioid with no significant absorption from the gut and does not cross the blood–brain barrier when used at normal doses
I’ve heard of heroin addicts taking Immodium before but didn’t know that connects to Loperimide until looking it up. I want to say in some places, stores have had to resort to keeping it behind the counter. I think in addition to helping with wd’s people try to get high off it as well. Taking too much is bad news like you said.
So I guess it just plugs into your opiate receptors. I never knew Immodium was an opioid..
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Orange clock, pencil "They threw me off the hay truck about noon..."
*Mark 15:34  Gam zeh ya’avor...
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deadwk
00101011


Registered: 06/17/09
Posts: 8,890
Loc: Canada, eh?
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Yea its actually really cool, my mind was blown for when I found out. I think you can even take a combination of 2 different substances + loperamide that will make it cross the blood brain barrier, except it will probably kill you due to the potency.
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gopher
Coffee Bean Extraordinaire



Registered: 11/22/17
Posts: 12,996
Loc: Canada
Last seen: 2 seconds
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Re: Kratom [Re: deadwk]
#26450456 - 01/24/20 06:08 PM (4 years, 5 days ago) |
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I found a great sourdce of kratom information can be had by a user named azulkat on reddit, like twice a month I read through his posts, he only posts in the kratom sub-reddit and he is pretty smart and posts like everyday
https://www.reddit.com/user/Azulkat
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Tight Lunchbox
Drunk cat


Registered: 11/06/16
Posts: 2,116
Last seen: 4 months, 7 days
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Quote:
metalfaith said: I started using kratom occasionally. Then regularly. The daily.
And you know, I knew it was an opioid, whereas you seem to he hiding that fact. Even knowing all that I still ended dependent. Took over a year, but it did happen.
Never had real opiate withdrawl but dang the insomnia makes it very difficult to quit. Who has 3-5 days to throw away?
With infrequent use, it is beautiful. If you lose diligence though, you will be dependent and not even catching a buzz.
I've noticed that withdrawal from kratom varies greatly from person to person.
With frequent use the worse symptoms of withdrawal I've experienced include lethargy and loose dumps. I take Imodium and coffee and am normal in 36 hours. This is from taking 7.5 to 10 grams a day for usually 1 to 3 months at a time.
I have some pretty intense craving for it whenever I quit, which is weird considering how mild it is relative to other drugs.
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TheUltimateBohab
Fat and Slobby


Registered: 09/05/18
Posts: 319
Loc: LV-426
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Yeah I started realizing after a couple of times trying this that I didn't like it very much it increase is my heart rate and gives me panic attacks and sweat only from small amounts so I stopped really doing it
-------------------- *DISCLAIMER* Everything I say on here is BULLSHIT!! I lie so I can kick it...
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