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theRealrollforever
I DID-DENT



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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: DJ Ed] 1
#26426909 - 01/10/20 04:55 PM (4 years, 19 days ago) |
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Nah you will not get dependent on tryotamines. You’ll lose your mind first. Source: eating lsd 7 days in a row in high school and getting a psychosis No withdrawals in the mental ward
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sunshine said: The order has to be secret and no one is sure.
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Buckomcdoogle
Atypical obsessive.


Registered: 11/27/19
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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: nooneman]
#26426915 - 01/10/20 04:57 PM (4 years, 19 days ago) |
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"Ketamine is a dissociative, not a psychedelic"
I can't speak from personal experience, but they way people describe the K hole, it seems pretty psychedelic.
-------------------- "Nothing is more dangerous to your creativity than comfort and familiarity" "Nihilism is the most basic truth in existence, the only consistency throughout the world, and the universe is chaos and decay" "Logic leads to nihilism"
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theRealrollforever
I DID-DENT



Registered: 08/31/13
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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: Buckomcdoogle]
#26426917 - 01/10/20 05:00 PM (4 years, 19 days ago) |
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U should do the drug u are gonna speculate about first K is super addicting and almost abusable like opiates to some ppl L and mush are not they are not anxiolytics or enjoyable to ‘abuse’
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sunshine said: The order has to be secret and no one is sure.
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BabylonRuleDem
Dude... I'm so liQuiD



Registered: 06/15/12
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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: Buckomcdoogle]
#26426924 - 01/10/20 05:04 PM (4 years, 19 days ago) |
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Quote:
Buckomcdoogle said: "Ketamine is a dissociative, not a psychedelic"
I can't speak from personal experience, but they way people describe the K hole, it seems pretty psychedelic.
Quote:
InfiniteDreams said: Tryptamine is a chemical classification. Ketamine is not a tryptamine.
Psychedelic is a broader drug classification that relates to the user's experience. Ketamine is definitely psychedelic, but its chemical/biological action is much different from tryptamines.
So to the original question, no it is not possible to become dependent on tryptamines from a chemical standpoint. Some people, however, are addicted to altered mind states in general, and tryptamines may be included in their pursuit of an ever altered perception.
Ketamine is psychedelic and addictive, but it is not a tryptamine.
-------------------- When we all get strange, and we know it, but we're cool with it
Trade List(WIP)
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Buckomcdoogle
Atypical obsessive.


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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: theRealrollforever]
#26427018 - 01/10/20 06:15 PM (4 years, 19 days ago) |
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Oh no, botanicals only for me.
I never said it was a tryptamine
Someone earlier in the thread said "You cannot get withdrawals from psychedelics"
SUPER SIZED ME (WITH INDOLES)
Id imagine itd turn out something like this, but more crazy, dysfunctional and incoherent.
-------------------- "Nothing is more dangerous to your creativity than comfort and familiarity" "Nihilism is the most basic truth in existence, the only consistency throughout the world, and the universe is chaos and decay" "Logic leads to nihilism"
Edited by Buckomcdoogle (01/10/20 06:17 PM)
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InfiniteDreams


Registered: 10/25/19
Posts: 1,224
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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: Buckomcdoogle]
#26427073 - 01/10/20 06:39 PM (4 years, 19 days ago) |
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Maybe more relevant to the drug in question (Lost in the K Hole):
(Did like that 30 day whisky challenge though, hilarious!)
Edited by InfiniteDreams (01/10/20 07:05 PM)
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mu5h13
Counsellor


Registered: 06/06/19
Posts: 67
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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: Buckomcdoogle] 1
#26427823 - 01/11/20 10:15 AM (4 years, 18 days ago) |
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Quote:
Buckomcdoogle said: "Ketamine is a dissociative, not a psychedelic"
I can't speak from personal experience, but they way people describe the K hole, it seems pretty psychedelic.
I can see why people would class the hole as a psychedelic experience but it's nothing like serotonergic psychedelics. It's about as psychedelic as muscimol.
Because its a kind of anaesthetic, the (true) k-hole is basically like a sensory void. Like imagine LSD but with total sensory deprivation and without the drug having it own "character". It just you in an eternal nothingness, and for some people (myself included in previous years) that nothingness can be as comforting as it is terrifying.
Back to the original question, I think everyone's dependent on tryptamines (serotonin etc..), but the tryptamine psychedelic experience is like a tolerance break from the standard tryptamines (by replacing them with different tryptamines). So then you can come back to your endogenous tryptamines with a new-found appreciation for the lens they give you in normal life.
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pepe the frog
Stranger



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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: Buckomcdoogle] 1
#26427893 - 01/11/20 11:00 AM (4 years, 18 days ago) |
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I dose daily sometimes for weeks typically. Have not noticed any tolerance building just that the entities get fed up with seeing me so often, but they learn to deal and are aware of the neo-shamanism path I currently travel. Also I do it daily for spiritual purposes rather than “enjoyment” as daily use is far from enjoyable.also tryptamines are built into humans. Dmt is endogenous as are many other variations of tryptophan. One could certainly become psychologically addicted to the rush, blissful euphoria, but the psychotropic effects make this rather difficult. Also I am totally sane, never even had a question in my mind otherwise. Depends on the reasons for partaking in the spice, the person taking it as well. I hope I was helpful. Thanks fren!
-------------------- The English biologist, Dawkins , invented the word MEME. Do you all know what a MEME is? It's the smallest unit of an idea. It's like what a gene is to biology, a MEME is to ideology. Our task is to create MEMES.....Shadilay frens
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PrimalSoup
hyperspatial illuminations



Registered: 11/17/09
Posts: 13,568
Loc: PNW
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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: DJ Ed]
#26428316 - 01/11/20 03:03 PM (4 years, 18 days ago) |
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Quote:
DJ Ed said: Personally speaking, obviously the tolerance build up is a problem (relevant when I was 20 and wanted to trip every week), but I think for me the limiting factor that is anti-addictive, is the anxiety.
My hypothesis is that unless there are people who do not actually get the before-dosing anxiety and the come-up anxiety, then this anxiety will stop anybody getting “addicted”.
Just my half-baked not well researched thoughts, Take care, DJ Ed
Anxiety of the come-up is not a problem at all if you're dosing daily. I've done OEV level trips 3-5 days on mushrooms for months at a time while writing and for research into the effects of the tripping (unitary) mind on local reality, and the come-up (from acidified tea) is just saying hi to an old friend after a while.
Tolerance peaks after about a week when the fresh dose has gone from 35-50 g to 200-250 g. I find it requires 50% more each successive day (so 50 - 75 - 110 - 170 - 250) but that's all it takes. Obviously you want to be doing tea at those levels, and I can brew it so that I get 250 g fresh into 125 cc of tea - 3 easy chugs with a chaser and done.
I've never found any dependency or addiction from mushrooms, other than the usual love of hyperspace. I've gone from tripping heavily to a 10 year break, and recently had about 3 years off. But I'm growing for a summer of full on experimentation again. 
A lot of the research is written up in my journals.
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if you stand too close to the machine it'll start to eat youPrimal's simple tested teks and projects: Wheat Prep 2.0 Acidic Tea Tek Potency Project!
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DJ Ed
Mushroom Engineer


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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: PrimalSoup]
#26428414 - 01/11/20 03:56 PM (4 years, 18 days ago) |
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I can see where you’re coming from, with that discussion. I have started to embrace it as “an old friend”. Funny that.
There’s some fascinating reads in your journal 👍🏻👍🏻👍🏻
-------------------- “It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.” Michael Pollan: How To Change Your Mind “The problem is not to find the answer, it’s to face the answer.” Terence McKenna

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individualist
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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: The Mycologist]
#26504776 - 02/26/20 12:14 PM (3 years, 10 months ago) |
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Quote:
The Mycologist said: Tolerance is so quick its pretty difficult. After sometime you are just eating shrooms for calories lol.
But this reminds me of True Hallucinations. Mckennas book about when he went to the Amazon. They were eating shrooms daily and got pretty spun so who knows.
Two summers ago I was having a gangbusters hunting season, bringing home 1-300 fresh grams of cubensis every day. I made myself virtually immune to psilocybin. I remember one night I ate 100 grams fresh and 4 to 5 grams dry and reached a mild level 1.
You just can't do it. They won't let you. You could probably reach a point where you are injecting IV psilocin and nothing happens.
-------------------- Question with boldness
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DJ Ed
Mushroom Engineer


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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: individualist]
#26505014 - 02/26/20 02:59 PM (3 years, 10 months ago) |
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Just a thought people on tolerance, bear with me!
There are many discussions on people failing to trip while they are on SSRIs. It is known that SSRIs work on the same 5-HT2a receptors as Psilocin; the SSRIs (selective serotonin reuptake inhibitors) are known to work by blocking serotonin from entering these 5-HT2a receptors. And yes, while they are blocking these receptors, psilocin cannot get in and do its magic.
Bear with me people, I’m getting there 😎
So now let’s reverse the situation; you’ve taken your mushroom tea, the psilocin has entered your brain and blocked the 5-HT2a receptors, and done their magic.
In fact it was so magic......you take another cup of mushroom tea the following day. But, those pesky 5-HT2a receptors are still completely, possibly partially, blocked from the previous night’s psilocin. So you don’t trip as hard.
Have I just stumbled on the answer to tolerance? Is the resident DJ Ed a genius?
Who knows though people, just a crazy stoned idea, but isn’t that where the best hypotheses come from?
Mush love all, DJ Ed
-------------------- “It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.” Michael Pollan: How To Change Your Mind “The problem is not to find the answer, it’s to face the answer.” Terence McKenna

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PrimalSoup
hyperspatial illuminations



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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: DJ Ed]
#26505054 - 02/26/20 03:34 PM (3 years, 10 months ago) |
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I think tolerance is a feature of altering homeostatic setpoints in the brain's production/use of neurotransmitters. This explains why the onset is so fast but the restoration is so much slower, much longer than the persistence of actives in the bloodstream.
Also, quick acting tryptamines like DMT don't result in appreciable tolerance - they get in and out before the brain would respond to the altered neurochemistry.
In any case IME there's a limit to tolerance and if you dose to that level (I found it around 250 g fresh ordinary cubes taken as tea) you can dose every day for as long as you like and still trip heavily. 
But when you stop there's a few days of markedly reduced reactions to normal stimulation - a blunted affect that dissipates rapidly. As close to a hangover as mushrooms can deliver.
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if you stand too close to the machine it'll start to eat youPrimal's simple tested teks and projects: Wheat Prep 2.0 Acidic Tea Tek Potency Project!
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DJ Ed
Mushroom Engineer


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Re: Is it actually possible to become depenent on Tryptamines?? Or would you just lose your mind first? [Re: PrimalSoup]
#26505772 - 02/27/20 01:16 AM (3 years, 10 months ago) |
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I knew it was just my stoned brain tricking me with easy answers! “Back in the day”, we used to call those days off after a few days on, as “having your head done in”. I remember feeling completely flat, with no motivation, no joy (a bit like depression, but not like an mdma come down), and fucked up thoughts playing with my mind for days, weeks, and at the end months!
These days, back to back tripping for me equates to once a week; I would only do this though if the previous trip had not “broken through”. Having a wife and family has given me responsibility that I didn’t have in my 20s.......
❤️ DJ Ed
-------------------- “It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.” Michael Pollan: How To Change Your Mind “The problem is not to find the answer, it’s to face the answer.” Terence McKenna

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