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Offlinedrinkkykeon
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Registered: 10/11/19
Posts: 113
Last seen: 3 months, 7 days
Johns Hopkins Bayview Medical Center smoking experiment used 30 gram psilocybin dosage?
    #26410381 - 01/01/20 02:56 AM (4 years, 28 days ago)

When I listened to this podcast the first time I wasn't aware of dosage details. Now that I've tripped a few times I can't understand why they used 30 grams as the dose. This seems obscenely high to me and in my personal experience most first timers should not approach anything over 10 grams.

https://www.npr.org/2019/10/01/766057380/how-magic-mushrooms-can-help-smokers-kick-the-habit

Am I missing something? Is the form of psilocybin they used drastically different than home grown golden teachers? I can't understand why such a high dose was used or how the participants managed to make it though without vomiting.


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OfflineDJ Ed
Mushroom Engineer
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Registered: 09/04/16
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Re: Johns Hopkins Bayview Medical Center smoking experiment used 30 gram psilocybin dosage? [Re: drinkkykeon]
    #26410386 - 01/01/20 03:06 AM (4 years, 28 days ago)

I haven’t listened to the podcast, simply read the web page, so I cannot fully respond to your query. But from the Roland GriffithsnTedX talks, the 30 g is not psilocin. It reconciles down to approx 5g dried cubensis. Check out the dosage calculator on the Shroomery where you can check how the figures work out for yourself.

Hope this helps,
DJ Ed


--------------------
“It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.”
Michael Pollan: How To Change Your Mind

“The problem is not to find the answer, it’s to face the answer.”
Terence McKenna



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InvisibleKaruna
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Registered: 08/02/17
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Re: Johns Hopkins Bayview Medical Center smoking experiment used 30 gram psilocybin dosage? [Re: drinkkykeon]
    #26410420 - 01/01/20 04:17 AM (4 years, 28 days ago)

I imagine it was 30 milligrams as they would've been using pure psilocybin rather than dried mushrooms.

In this smoking cessation study they used 20 and 30mg per 70kg body weight.


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OfflineKorean Jesus
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Re: Johns Hopkins Bayview Medical Center smoking experiment used 30 gram psilocybin dosage? [Re: Karuna]
    #26410543 - 01/01/20 07:37 AM (4 years, 28 days ago)

JOHNSON: I mean, it might look different after 30 milligrams of psilocybin.

SOFIA: Biologically, that's a safe dose for the average person. But to be clear - 30 milligrams is a lot of psilocybin.


Indeed, using .67% psilocybin in each gram of mushrooms (this is an average – it varies wildly), 30*100/.67 = 4477mg = almost 5g shrooms. This is basically the heroic dose, as they point out.


--------------------
:rastamon::getstoned::rastamon:


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Invisiblebadchad
Mad Scientist

Registered: 03/02/05
Posts: 13,372
Re: Johns Hopkins Bayview Medical Center smoking experiment used 30 gram psilocybin dosage? [Re: Karuna]
    #26410729 - 01/01/20 10:45 AM (4 years, 28 days ago)

Quote:

drinkkykeon said:


Am I missing something? Is the form of psilocybin they used drastically different than home grown golden teachers? I can't understand why such a high dose was used or how the participants managed to make it though without vomiting.




Yeah, your dosing information is off.  The post below has the correct info.

Quote:

Karuna said:
I imagine it was 30 milligrams as they would've been using pure psilocybin rather than dried mushrooms.

In this smoking cessation study they used 20 and 30mg per 70kg body weight.




--------------------
...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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Offlinedrinkkykeon
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Registered: 10/11/19
Posts: 113
Last seen: 3 months, 7 days
Re: Johns Hopkins Bayview Medical Center smoking experiment used 30 gram psilocybin dosage? [Re: badchad]
    #26410800 - 01/01/20 11:40 AM (4 years, 28 days ago)

Thanks guys I had the units wrong. 30 mg NOT grams.


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