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Offlineazramb
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Registered: 06/16/18
Posts: 505
Last seen: 3 years, 9 months
Re: Why Chronic Microdosing Might Break Your Heart [Re: Korean Jesus]
    #26404585 - 12/28/19 12:06 PM (4 years, 1 month ago)

Quote:

Korean Jesus said:
Quote:

Bill_Oreilly said:
Quote:

Korean Jesus said:
Quote:

PrimalSoup said:
:lol:  Uhm, really you just do it.  Kind of like swimming.



I'd trip more if I weren't concerned about my vision





dude youre fine, stop with that. You are very new to tripping and if you REALLY had eye problems from tripping just a few times, i would never trip again and go to a doctor.

its all in your head



hopefully bro :smile:



Honestly I do think it's highly likely that your visual distortions are being caused by your anxieties about it. Not true hppd. Anxiety can cause visual distortions to.


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OfflineKorean Jesus
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Registered: 11/13/19
Posts: 554
Loc: United States Flag
Last seen: 2 years, 6 months
Re: Why Chronic Microdosing Might Break Your Heart [Re: azramb]
    #26404646 - 12/28/19 12:48 PM (4 years, 1 month ago)

Then why do they slowly subside over time and why does weed, which reduces anxiety unless taken in high doses, exacerbate them massively while high?

No way “anxiety” is causing a vivid recognizeable afterimage of my laptop screen when I close my eyes after looking at it when I wake up.


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:rastamon::getstoned::rastamon:


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Invisibleredgreenvines
irregular verb
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Registered: 04/08/04
Posts: 37,531
Re: Why Chronic Microdosing Might Break Your Heart [Re: Korean Jesus]
    #26404721 - 12/28/19 01:28 PM (4 years, 1 month ago)

how did they explain that lsd is bad for heart valves, while serotonin is not bad for heart valves and both bind to the same sites, and we always have some serotonin.

How tightly molecules bind to the receptor site, and how frequently the receptor site is maintained (replaced by the cells that produce them) relates a lot to tolerance and activity, I guess fenfluramine bound very tightly and blocked receptor maintenance leading to dangerously enlarged valve tissue.

I think there are problems with this kind of research, fenfluramine is a whole other ball of wax, and I never believed that full on stimulants are heart healthy anyway, BP goes too high regardless of binding sites.


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:confused: _ :brainfart:🧠  _ :finger:


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OfflinePrimalSoup
hyperspatial illuminations
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Registered: 11/17/09
Posts: 13,568
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Re: Why Chronic Microdosing Might Break Your Heart [Re: NOUS333]
    #26404858 - 12/28/19 02:49 PM (4 years, 1 month ago)

Quote:

NOUS333 said:
Quote:

PrimalSoup said:
:lol:  Uhm, really you just do it.  Kind of like swimming.




Well. Maybe its different for you.  I get really attached to thoughts and very ‘involved’ with what goes on in my head even when im just sober but especially tripping.  Out of all my trips maybe 1 or 2 were cognitively light and fun experiences. The rest have all been deeply spiritual and transition points in my life that had me processing shit for months if not years.   

The last trip i had was so powerful, 6 years ago, when i thought of tripping again 2 years ago all i had to do was go out and buy a strainer and stuff to make tea, i think i made the tea and took one sip and realized i was fooling myself. I knew what i had to do in my life and i knew the mushrooms were just going to tell me the same thing. I got serious with my self, got serious about listening my higher intuitions and ive really come a long way since. All because i only thought about tripping. 

I kinda wish i could just trip recreationally but whatever spiritual associations ive made in my brain with tripping whether they are false or not have really helped me get my shit together and take life seriously.      I kinda wish i could talk to you in person though, ive never met anyone who has tripped that much....feel like we could have some interesting conversations. 

.




Ya know the more experience you have, in many ways the easier it gets to not get screwed up, but there's always some risk.  The difference is learning how to let go completely when needed, let go of all of it, all the preconceptions, all the associations, and just be.  When they show you what has to be worked on (and they will) then you gotta go work on it.  That's why "like swimming" - it's still dangerous (you COULD drown) and you have to work through your fear (you WON'T drown) and you have to lose any fear that saps your strength to do it well...

I did a lot of mediation in and around the time I started tripping heavily.  The two go together IME.  You can look at whatever's happening and just think "sense impression" rather than allowing it to take control.  That can be helpful.

Anyway good tripping. :cookiemonster:


--------------------

if you stand too close to the machine it'll start to eat you
Primal's simple tested teks and projects: :awesomenod: Wheat Prep 2.0  Acidic Tea Tek  Potency Project! 


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Invisiblewombat66
####
Registered: 11/02/01
Posts: 40
Re: Why Chronic Microdosing Might Break Your Heart [Re: PrimalSoup]
    #26404979 - 12/28/19 04:01 PM (4 years, 1 month ago)

Dr. David Nichols, one of the foremost academic authorities on LSD, has also been warning microdosers of potential heart valve damage via the 5HT2b receptor. And one should remember that Sasha Shulgin, a close friend of Nichols, had heart valve replacement surgery in 2008.


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InvisibleBill_Oreilly
ANIMALS (the RAINBOW SERPENT)


Registered: 11/12/11
Posts: 26,370
Loc: Boston
Re: Why Chronic Microdosing Might Break Your Heart [Re: wombat66]
    #26405117 - 12/28/19 05:40 PM (4 years, 1 month ago)

So many people need heart valve replacements. Both my grandparents needed one and they are everything opposite of a psychedelic user.


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Something there is mysteriously formed,
Existing before Heaven and Earth,
Silent, still, standing alone, unchanging,
All-pervading, unfailing,
I do not know its name; I call it tao.
If forced to give it a name, I call it
Great (ta). Being great, it flows out;
Flowing out means far-reaching;
Being far-reaching, it is said to return.


It's just a shot away..


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OfflineBlabble40
Scorpio

Registered: 11/11/14
Posts: 1,182
Last seen: 1 year, 27 days
Re: Why Chronic Microdosing Might Break Your Heart [Re: Bill_Oreilly]
    #26405121 - 12/28/19 05:43 PM (4 years, 1 month ago)

All true. Smoking doesn't help either. I'd watch it. Peer pressure isn't your friend.


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Edited by Blabble40 (12/28/19 05:44 PM)


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OfflineBlabble40
Scorpio

Registered: 11/11/14
Posts: 1,182
Last seen: 1 year, 27 days
Re: Why Chronic Microdosing Might Break Your Heart [Re: Blabble40]
    #26405453 - 12/28/19 10:09 PM (4 years, 1 month ago)

I suspect it’s also where the phrase “You’re tuggin’ on my heart strings,” comes from.


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Offlinerandompsychedelic
Stranger
Registered: 07/18/23
Posts: 3
Last seen: 5 months, 24 days
Re: Why Chronic Microdosing Might Break Your Heart [Re: HamHead]
    #28406385 - 07/24/23 12:03 PM (6 months, 2 days ago)

Hi would you be interested to participate in a research study trying to answer this question? All data is de-identified and you'd get a free heart echo (ultrasound) and check-up, and you'd help other fellow users stay safe. Let me know.
Are you interested to participate in research study assessing the cardiac safety of traditional psychedelics which include LSD and psilocybin?
You may choose only one


Votes accepted from (07/24/23 09:03 AM) to (No end specified)
You must vote before you can view the results of this poll



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Invisibleredgreenvines
irregular verb
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Registered: 04/08/04
Posts: 37,531
Re: Why Chronic Microdosing Might Break Your Heart [Re: randompsychedelic] * 1
    #28406445 - 07/24/23 01:03 PM (6 months, 2 days ago)

I had an extensive 45 minute echocardiogram heart ultrasound (angiogram) because of an aberration on an ECG suggesting RBB.

My problem was not related to valvular heart disease, but to  excess iron accumulating and interrupting some bundle branch signals - leading to a laggy ventricle contraction.

my ticker still works fine, however, and I know how the iron got there (a medical doctor's wrong prescription which cost 1000's of dollars over several years - damn!)

I have been microdosing and minidosing at the maximum rate (in the shadow of thresholds) for at least 20 years.

no valve problem here.

the 45 minute angiogram involved several continuous efforts, a quart of lubricant smeared all over my upper body and keeping still in some very crampy positions.


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:confused: _ :brainfart:🧠  _ :finger:


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