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OfflineJohnRainy
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Registered: 07/09/19
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Re: Psilocin extraction internet recipe [Re: spiritlands] * 1
    #26387801 - 12/17/19 08:43 PM (4 years, 1 month ago)

Ethyl Acetate it is then.

Good stuff.


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InvisibleFeasoghorm

Registered: 10/24/18
Posts: 4,384
Re: Psilocin extraction internet recipe [Re: JohnRainy]
    #26387866 - 12/17/19 09:51 PM (4 years, 1 month ago)

Yeah i dnt understand much of all that chemistry speak, but get a vapor mask and a sweet pair of safety glasses while your at it.
MEK is really nasty shit. It'll mutate your sack.


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Offlinespiritlands
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Re: Psilocin extraction internet recipe [Re: Feasoghorm]
    #26387867 - 12/17/19 09:55 PM (4 years, 1 month ago)

Ha ha, my sack is already mutated. That's what I need the 1000x zoom microscope for. This isn't mek, it's mek substitute ethyl acetate. Any solvent fumes will be trapped in the water bucket for the most part. This won't be an issue as long as we're not evaporating large amounts of solvent.


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OfflineFailboat
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Re: Psilocin extraction internet recipe [Re: spiritlands]
    #26387882 - 12/17/19 10:16 PM (4 years, 1 month ago)

The final result would be insufflatable?


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InvisibleFeasoghorm

Registered: 10/24/18
Posts: 4,384
Re: Psilocin extraction internet recipe [Re: Failboat]
    #26387898 - 12/17/19 10:45 PM (4 years, 1 month ago)

Cud i smoke it? I like smoking things.


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OfflineJohnRainy
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Re: Psilocin extraction internet recipe [Re: Failboat]
    #26387907 - 12/17/19 11:03 PM (4 years, 1 month ago)

Quote:

in·suf·flate
/ˈinsəˌflāt/

verb
past tense: insufflated; past participle: insufflated
1.
MEDICINE
blow (air, gas, or powder) into a cavity of the body.
2.
THEOLOGY
blow or breathe on (someone) to symbolize spiritual influence.






That's a good question.  Could you snort crystal psilocin?  Would the product be suitable for that?

It can't be kept exposed to the air or it will oxidize and become inactive, so, practically, not really.  But right after you made it and before you mixed it in something, I guess you could snort it?


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Offlinespiritlands
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Re: Psilocin extraction internet recipe [Re: JohnRainy]
    #26387949 - 12/17/19 11:59 PM (4 years, 1 month ago)

I don't know but I can see if shulgin tried that when I get home. His book tihkal has hundreds of compounds he synthesized and then administered all sorts of ways with trip reports for each. He's done more psychedelics than anyone in the planet prob.


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OfflineJohnRainy
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Re: Psilocin extraction internet recipe [Re: spiritlands]
    #26387962 - 12/18/19 12:15 AM (4 years, 1 month ago)

Somehow Ive never heard of this guy until now.


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Offlinespiritlands
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Re: Psilocin extraction internet recipe [Re: JohnRainy]
    #26387971 - 12/18/19 12:30 AM (4 years, 1 month ago)

Alexander shulgin

Pihkal

Tihkal

Another good author is Otto snow

Uncle Fester and I were pen pals for a long time. His books have good info but he doesn't write in a step by step format so to the uninitiated it is easy to miss things that an experienced chemist would have an unspoken understanding of. He knows his shit though. All my books are autographed to 'spirit' and I still have his letters. Old school, hand written letters.


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InvisibleDigit
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Re: Psilocin extraction internet recipe [Re: spiritlands] * 1
    #26389215 - 12/18/19 05:29 PM (4 years, 1 month ago)

My advice as someone who has personally done a fair amount of synthesis and extractions is to take the time to learn the basics of acid/base extraction, the differences in solubility of your target compound in different solvents and basic lab safety. Playing around with solvents, acids and strong bases without the knowledge of what you're doing can seriously burn you, set your house on fire or poison you. At best you will end up wasting a lot of mushrooms and end up with a toxic, caustic goo that gets you more poisoned than high.
It's not rocket science, but it's definitely not like baking a cake.


--------------------
Question everything.
Believe nothing.
Think for yours3lf.


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OfflineJohnRainy
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Re: Psilocin extraction internet recipe [Re: Digit]
    #26389666 - 12/18/19 09:42 PM (4 years, 1 month ago)

An acid-base extraction is a type of liquid-liquid extraction. It typically involves different solubility levels in water and an organic solvent. The organic solvent may be any carbon-based liqiuid that does not dissolve very well in water; common ones are ether, ethyl acetate, or dichloromethane.


The intrigue with this is very strong for me.

While I appreciate the warning, I find it hard to heed.

It doesn't seem like that crazy of a process to me.  It's not like Im trying to make LSD from some sketchy internet posts or something.  That would be silly, but this? 


I know that ethyl acetate is in the same league as gasoline when it comes to flammability, and to be fucking careful with something called concentrated ammonium hydroxide.  Im planning on wearing a respirator with activated carbon cartridges to absorb any organic vapours from the organic solvent, safety glasses, and have an exhaust fan running.

I will cut my teeth on this with a small batch involving a few hundred milliters of solvent.  I expect to see a green residue as the authors have said.  I will test a very small amount of it at first.

Should be good.  Im looking forward to the other guy who is interested in this too and more knowledgable about chem than I am to give us an update.


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Offlinespiritlands
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Re: Psilocin extraction internet recipe [Re: JohnRainy]
    #26389778 - 12/18/19 10:42 PM (4 years, 1 month ago)

Safety and proper knowledge of the properties of all chemicals involved is key. It's good to have a healthy respect for chemicals. I think that ppl have unnecessary fear of chemicals bc most of the chemicals ppl encounter are fairly benign. There are only a few chemicals that scare me, formic acid and methylamine are extremely powerful. I refuse to work with hydrofluoric acid. Nothing good comes from fluorine. I will be using household ammonia and household vinegar, same thing you clean with, nothing to fear. I need to pick up some pH strips before I concentrate the acetic acid in the vinegar. Before I start anything I'll post the chemspider links to chemicals involved. Gonna try to get that done and posted by the weekend. Fresh flush went in the dehydrator this morning. I'll be doing a ten gram batch as the document calls for.


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Offlinespiritlands
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Re: Psilocin extraction internet recipe [Re: spiritlands]
    #26394974 - 12/22/19 04:30 AM (4 years, 1 month ago)


Acetic acid data sheet
Looking everywhere for pH strips. Gonna have to order them. With the holidays who knows when they'll get here. Moving on. Household white distilled vinegar. Put in the refrigerator for a few hours. The water is still liquid but the acetic acid that wasnt bound to water froze and can easily be filtered. I just put the vinegar in a bottle and poked holes in the lid for when it comes time to drain and filter crystals. At this point I flipped the bottle upside down in a cup and left it in the fridge for another couple hours. This allows water to drain but acetic acid is solid and it's trapped in the bottle. This process is done in the fridge bc acetic acid quickly melts and will run off remixing with the water which is what we don't want. What we are doing is called fractional crystallization/ fractional freezing.


Edited by spiritlands (12/22/19 04:42 AM)


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InvisibleDigit
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Re: Psilocin extraction internet recipe [Re: spiritlands]
    #26400629 - 12/25/19 04:16 PM (4 years, 1 month ago)

There is no reason to concentrate the acetic acid from vinegar to use for this purpose. The point is to do the acid side of the extraction with dilute acetic acid at pH4. Vinegar IS dilute acetic acid and is normally at around pH4 straight from the bottle.
Furthermore, ethyl acetate has extremely different properties from ethyl ether. I'd be very, very surprised if freebase psilocin will dissolve in it, since it is a much more polar molecule than ethyl ether. Instead you'd probably be better off using naptha, xylene or toluene. However remember that if you evaporate store-bought solvents any impurities in them will be concentrated. This can include heavy metals and various toxic hydrocarbons that do not evaporate with the solvent.
Most importantly, you're dealing with a highly unstable molecule that likes to degrade into inactive shit under light, heat and oxygen. That's why you need to evaporate it under a vacuum, which I can guarantee you will not be able to create any kind of proper vacuum using a ball point pen. Sorry, but if you've ever seen a real vacuum aspirator it's not that simple.
Above all, mushrooms are not meth, they're natural medicine from our earth and they're just fine as is, there is no reason on earth to use a bunch of chems and make a bunch of fumes and/or hazardous waste when you could just make tea instead.


--------------------
Question everything.
Believe nothing.
Think for yours3lf.


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Offlinespiritlands
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Re: Psilocin extraction internet recipe [Re: Digit]
    #26401096 - 12/26/19 01:14 AM (4 years, 1 month ago)

The reason I am concentrating it is bc I already have acetic acid in the way but I have a bottle of 5% white distilled vinegar which is no where near 4ph. The acetic acid stays bound to water and freezing the mixture yeilds some of both on each side. I'm concentrating it to get an idea how much water CAN be removed through fractional freezing. I'm also waiting on pH strips nowhere had them locally it's not pool season.

About the ethyl acetate.. you're right. This isn't like manufacturing meth. Although technically the psilocin is a free base bc were not making a salt out of it, it has no issues dissolving in polar solvent or else tea and water extraction would not work. This isn't a case of polar vs non polar like many a/b extractions, this is a case of which solvent has a higher affinity for psilocin.

Aspirator
Lastly I have had expensive lab grade vacuum pumps and I can do the same thing with a bucket of ice water without having to regulate how much pressure my pump is pulling. This is an actual water aspirator and as you can see it's a very basic concept. I can pull 18-25 psi of vacuum in minutes using a ball point pen and a 't' fitting. Ppl use them everyday for cleaning fishtanks.

I was gonna wait for my things to come in the mail but I think I'll do a test run right now. Seems like we all want less talking about it, more being about it, right? Let's see what we get from 6.8g


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OfflineJohnRainy
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Re: Psilocin extraction internet recipe [Re: Digit]
    #26401100 - 12/26/19 01:20 AM (4 years, 1 month ago)

Hi.

Thank you for the criticism.  You raise some valid points.

I am not a chemist, and I wish someone could just authoritatively tell me if psilocin would extract into ethyl acetate using this method.  I don't have anything to indicate that it would not.  Ethyl acetate is named as a suitable replacement for diethyl ether in things Ive read online not specifically about psilocin extraction.

I did find something about alkaloid extraction, which is a pretty precise descriptor.  Psilocin is an alkaloid.  This is a very similar process

Quote:

To isolate alkaloids from plants, the dried and powdered plant material is extracted with pet ether (or hexane, colemans etc.) first. This removes fats, oils, terpenes, waxes etc. This extract is discarded.
The material is now subjected to an alcohol extraction, eg with methanol or ethanol. The extract is evaporated to leave the crude alkaloids mixture.
This extract is partitioned between an diluted aq. tartaric acid solution and ethyl acetate. Other acids like citric acid can be used, and other solvents may substitute here. The ethyl acetate layer contains neutral and weakly basic alkaloids. Evaporate the solvent to isolate them.
The aq. layer is neutralised with NH3 or Na2CO3 and again extracted with ethyl acetate. The organic layer now contains basic alkaloids, while the aq. layer contains quarternary ammonium ions.
Many alkaloids can be isolated directly from the alkoholic extract by chromatographic methods. This is a separation which works well for tropane alkaloids (atropine, cocaine, scopolamine).





https://www.researchgate.net/post/which_is_the_best_method_for_the_extraction_of_alkaloids_from_medicinal_plant_specially_from_leaves_what_are_best_solvents_for_the_extraction

I think that is big indication that psilocin dissolves in ethyl acetate.

The impurities in the solvent could be minimized by evaporating it through a condenser before using it for the extraction, if there are any impurities there at all.  And I was planning on using a real vacuum chamber anyways.

As for nature, the human mind is conditioned to want to constantly refine and further purify good things, no?  Im very curious to see what this is like.  Nearly pure psilocin.  Wouldn't that be so cool?
It still came from a mushroom...


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OfflineJohnRainy
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Re: Psilocin extraction internet recipe [Re: spiritlands]
    #26401112 - 12/26/19 01:43 AM (4 years, 1 month ago)

Cant wait to hear the results.  I hope there's pics.

Have you got a scale good enough to weigh the milligrams you'll get?


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Offlinespiritlands
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Re: Psilocin extraction internet recipe [Re: JohnRainy]
    #26401681 - 12/26/19 02:27 PM (4 years, 1 month ago)

I'll have a full write up tonight when I run the rest of the procedure. Got pH strips, got 30% acetic acid, got the last bits of tube for the aspirator. I did the main part of the extraction last night but I haven't tested the pH of the vinegar yet. I'll prob run it again now that my chemicals are in and compare the results. I have a scale with good resolution but I don't have a micro gram scale so I'll be making up for this by using larger extraction sample. I placed enough ethyl acetate to cover the bottom of a graduated cylinder and left it over night. It evaporated without leaving any residue. It's been 12 hrs. The aspirator will make quick work of this.

This is the solution in the beginning of the extraction. I left this on the stirplate for an hour. After the heating and filtration I'm left with this solution.

I've tried to capture the iridescent blue green tint. All color has come from the mushrooms, all solvents im using are clear.


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Edited by spiritlands (12/26/19 02:44 PM)


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OfflineJohnRainy
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Re: Psilocin extraction internet recipe [Re: spiritlands]
    #26401828 - 12/26/19 04:03 PM (4 years, 1 month ago)

Very nice.  So that's the acetic acid portion of this.

Can I ask how you filtered it?  Did you do the glass wool suction filtration? 

I was going to place the crushed mushrooms in a large fine mesh bag when they go into the acetic acid.  Thought that would make for a much easier filtration process.

Im dying to see what the ethyl acetate extraction yields...and if it's nice and active.

Also, if this is freebase psilocin, doesn't that mean it could be smoked?  That would be something alright.  What about vaped?  Holy shit that would rock.


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Offlinespiritlands
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Re: Psilocin extraction internet recipe [Re: JohnRainy]
    #26401883 - 12/26/19 04:58 PM (4 years, 1 month ago)

I just used two coffee filters and gravitaty filtration. The less you force through the filter the better product you will have. Vacuum filtration does help a lot but slow and gentle is the way to go with filtration. I had to pick up new tubes for the aspirator this morning. I usually use 10+ filters and vacuum filtration. I use the same jar for vacuum filtration that I do for evaping but I add an extra hole. I'll show that tonight when I set up. I imagine there are spores that made it through the filtration but I don't see any sediment. Ideally I would centrifuge the solution to remove and particulates that would interfere with crystallization.

The fine mesh bag would work (assuming you have bubble bags for hash) but I avoid using any glassware or filters with excessive surface area. The more surface your solution touches the more you will lose in the process. I keep things small and concentrated and I use as little solvent as possible.

As far as how to ingest I can't recommend anything, I'm not a doctor, I haven't tried smoking or vaping it. This is the first time I've tried extracting mushrooms. I do think this would be a good way to extract pans and use the extract to dose a batch of gummies or chocolate without all the mush material left in the batch. Well see what we have in the morning.


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