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InvisibleRevok
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FDA Warns of 'Serious' Respiratory Problems With Gabapentin * 1
    #26391857 - 12/20/19 06:13 AM (2 years, 7 months ago)

Life-threatening breathing difficulties can occur in patients who use gabapentin or pregabalin with opioids or other drugs that depress the central nervous system, as well as those with underlying respiratory impairment and the elderly, the US Food and Drug Administration (FDA) warned in a drug safety communication issued today.


"Reports of gabapentinoid abuse alone, and with opioids, have emerged and there are serious consequences of this co-use, including respiratory depression and increased risk of opioid overdose death," Douglas Throckmorton, MD, deputy director for Regulatory Programs at the FDA's Center for Drug Evaluation and Research, said in a statement.

https://www.medscape.com/viewarticle/922932


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Invisibletyrannicalrex
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: Revok]
    #26392026 - 12/20/19 09:15 AM (2 years, 7 months ago)

Well, as a nurse in pain management I expect to see more meds cut for the work comp people and the regular ones. WOW!


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InvisibleRevok
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: tyrannicalrex] * 1
    #26392036 - 12/20/19 09:21 AM (2 years, 7 months ago)

I've been prescribed Gabapentin and quit taking it due to its ineffectiveness towards any pain management. Frankly I was shocked when I discovered that there was a recreational market for it...

All these stories of abuse have made it harder for people who are fighting issues with pain.


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InvisiblePenroc3
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: tyrannicalrex]
    #26392198 - 12/20/19 11:59 AM (2 years, 7 months ago)

its not gabapentin the warning is for lyrica


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Invisibletyrannicalrex
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: Penroc3] * 1
    #26392223 - 12/20/19 12:14 PM (2 years, 7 months ago)

...may occur in patients taking gabapentin (Neurontin, Gralise, Horizant) or pregabalin (Lyrica, Lyrica CR) who have respiratory risk factors.


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Offlinemorrowasted
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: tyrannicalrex]
    #26392821 - 12/20/19 07:25 PM (2 years, 7 months ago)

"Taking Cns depressants increases your risk of respiratory failure"

Got it:rolleyes:


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InvisibleRevok
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: morrowasted]
    #26392828 - 12/20/19 07:32 PM (2 years, 7 months ago)

Your welcome!!!


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InvisibleRevok
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: Revok]
    #26392830 - 12/20/19 07:32 PM (2 years, 7 months ago)

You're*


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OfflineK3yBoardC0WBoy
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: Revok] * 1
    #26393509 - 12/21/19 07:29 AM (2 years, 7 months ago)

Not surprised and expected this to come after experiencing gabapentin, Thought it worked great for nerve pain but tolerance builds up faster with that then opioids, or least that is my belief. Seeing Europes issues with these things, knew it'd bleed over at some point.

Good post op!


Edited by K3yBoardC0WBoy (12/21/19 07:31 AM)


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InvisiblePsychoReactive
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: K3yBoardC0WBoy]
    #26393560 - 12/21/19 08:38 AM (2 years, 7 months ago)

All FDA approved drugs are dodgy.


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OfflineHamHead
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: PsychoReactive]
    #26393580 - 12/21/19 09:03 AM (2 years, 7 months ago)

Quote:

PsychoReactive said:
All FDA approved drugs are dodgy.




This is, so far today, the dumbest statement I've read.


--------------------
The Italian researchers’ findings, published by the INT’s scientific magazine Tumori Journal, show 11.6% of 959 healthy volunteers enrolled in a lung cancer screening trial between September 2019 and March 2020 had developed coronavirus antibodies well before February.

https://www.reuters.com/article/us-health-coronavirus-italy-timing-idUSKBN27V0KF

This online first version has been peer-reviewed, accepted and edited,  but not formatted and finalized with corrections from authors and proofreaders

https://www.icandecide.org/


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OfflinePumpJackTeX
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: HamHead]
    #26393617 - 12/21/19 09:36 AM (2 years, 7 months ago)

1 of the 3 looney bins that I had the honor of visiting prescribed me that shit.

Guess what motherfuckers?!

I was fucking right. I did not need ANY prescriptions.

I had a fucking autoimmune disease assholes.

All I had to do was quit eating gluten.

I have 0 trust in Modern American Healthcare.

I turned to them for help & got misdiagnosed & destroyed mentally.


--------------------
Life. 2008

Ascension Energy | UFOs | 2021


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Invisiblesh4d0ws
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: morrowasted]
    #26394010 - 12/21/19 03:04 PM (2 years, 7 months ago)

Quote:

morrowasted said:
"Taking Cns depressants increases your risk of respiratory failure"

Got it:rolleyes:




I know, why is the journalist (and doctors I guess too) acting like we just figured this one out

:flowstone:


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Invisiblesh4d0ws
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: PsychoReactive]
    #26394014 - 12/21/19 03:06 PM (2 years, 7 months ago)

Quote:

PsychoReactive said:
All FDA approved drugs are dodgy.




:archiebunker:


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Invisibletyrannicalrex
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: morrowasted]
    #26395537 - 12/22/19 02:21 PM (2 years, 7 months ago)

LOL, I just click the 1st search mostly and post. :shrug: I consider myself very lucky to not have to take these drugs nor any of my friends and family.


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Offlinemorrowasted
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: tyrannicalrex]
    #26396398 - 12/22/19 11:23 PM (2 years, 7 months ago)

Pregabalin gets a lot of negative press for being abused and gabapentin for "zombifying" people but it's actually a very safe drug in comparison to other options. It's certainly not for everyone, and probably is overprescribed, but for some people it works wonders. Also, it's not necessarily the stupefying drug people claim it is.

α2δ Ligands Act as Positive Modulators of Adult Hippocampal Neurogenesis and Prevent Depression-Like Behavior Induced by Chronic Restraint Stress

Effects of single and combined gabapentin use in elevated plus maze and forced swimming tests

Many many people are benefiting from the use of pregabalin and gabapentin and we should not be quick to stigmatize them.

All the article in the OP says is that gabapentinoids increase risk of respiratory failure. Anyone who works in healthcare already knew this. Only people who already have seriously compromised respiratory systems for other reasons are at risk of respiratory failure from gabapentinoids alone.


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Invisibletyrannicalrex
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: morrowasted]
    #26396905 - 12/23/19 09:34 AM (2 years, 7 months ago)

Yep!


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InvisibleHolybullshit
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: tyrannicalrex] * 1
    #26397144 - 12/23/19 12:26 PM (2 years, 7 months ago)

I am so sick of the FDA targeting gabapentin, especially as it may end up effecting me personally.

For one, gabapentin is hardly recreational(lyrica a bit more so I am told)....but it does help with opioid withdrawals, A LOT, and potentiates the opioid high a little. It also helps with a slew of co-occuring mental problems which lead people to seek out drugs of abuse in the first place...and is prescribed off label in this way about as much as it is prescribed for its FDA approved purposes.

Quote:

I've been prescribed Gabapentin and quit taking it due to its ineffectiveness towards any pain management.




I don't know what kind of pain you were taking it for, but its really only effective for nerve pain and even then you often have to manage your use of it for it to stay effective for any length of time.

Personally I take gabapentin(and fairly large amounts of it) for sciatica and neuropathy, and without it I won't say my life would be unbearable...but my quality of life would drop considerably as I would be completely unable to carry on the same lifestyle and would no longer be able to do any strenuous work or many physical activities...currently hiking, bowling, biking are pretty high up on my list of hobbies and I am a DIYer in the middle of rehabbing a house built in 1900 and there is no way in hell I would be able to accomplish this without gabapentin(excluding opiates of course).

It's honestly like the FDA just does not give one single fuck about people's pain...if a few of the wrong people take a certain drug the wrong way, they are perfectly content to have everyone else suffer because of it.


Edited by Holybullshit (12/23/19 12:27 PM)


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Invisibletyrannicalrex
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: Holybullshit] * 1
    #26397153 - 12/23/19 12:31 PM (2 years, 7 months ago)

It's honestly like the FDA just does not give one single fuck about people's pain.

BINGO! And I might add "life" to that statement. I'm seeing all kinds of prior authorizations needed for people who have obviously been on these and other meds for 10-20 plus years, and they need these meds just to function daily.


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Edited by tyrannicalrex (12/24/19 10:23 AM)


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Offlineprettyhatemachine
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Re: FDA Warns of 'Serious' Respiratory Problems With Gabapentin [Re: tyrannicalrex]
    #26398726 - 12/24/19 09:01 AM (2 years, 7 months ago)

The FDA is garbage, they ban sports supplements at the first sign of issues... but leave alcohol and tobacco legal :facepalm:


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