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OfflineNOUS333
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Registered: 12/26/15
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Microdosing and seizures
    #26385096 - 12/16/19 12:54 PM (4 years, 2 months ago)

Got a pretty straightforward question.  Have a friend who has a history of seizures. Wants to try microdosing.    Should they abstain or is this something that wouldnt be a problem and may even help prevent seizures?


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OfflineShroomhunts
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Re: Microdosing and seizures [Re: NOUS333]
    #26385131 - 12/16/19 01:12 PM (4 years, 2 months ago)

What kind of seizures? Epilepsy is frequently caused by masses in the brain in which case I would advise against psychedelic use.


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OfflineThe Mycologist
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Re: Microdosing and seizures [Re: Shroomhunts]
    #26385169 - 12/16/19 01:30 PM (4 years, 2 months ago)

I would avoid LSD if you have history of seizures. Thats only because the other LSD analogs are seizure causing. (The ones that are not LSD-25) So it makes me wonder the relationship.


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"That you are here—that life exists, and identity;
That the powerful play goes on, and you will contribute a verse.”
― Walt Whitman, Leaves of Grass
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OfflineNOUS333
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Re: Microdosing and seizures [Re: The Mycologist]
    #26385401 - 12/16/19 03:43 PM (4 years, 2 months ago)

Im talking microdosoing mushrooms and i think they are epileptic seizures.


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OfflinePandemoon
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Re: Microdosing and seizures [Re: NOUS333]
    #26386573 - 12/17/19 07:35 AM (4 years, 2 months ago)

I think a microdose won't cause any seizure. A microdose is not tripping.
Tripping hard can cause seizures, though, I now from experience.

-


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OfflineNOUS333
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Re: Microdosing and seizures [Re: Pandemoon]
    #26386712 - 12/17/19 09:26 AM (4 years, 2 months ago)

I wish i could find solid research or evidence that it might help prevent seizures. Ive found indovidual accounts online but im still worried about friend trying to microdose and having a seizure


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Invisibleopenmind
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Re: Microdosing and seizures [Re: NOUS333]
    #26387449 - 12/17/19 04:29 PM (4 years, 1 month ago)

Quote:

NOUS333 said:
I wish i could find solid research or evidence that it might help prevent seizures....





There is a member here on the shroomery that has epilepsy of sorts...They say that having a trip with LSD or mushrooms seems to prevent or at least lessen their occurrence of seizures. I forget the #'s they spoke about, but after having a trip on LSD they said they experienced a big decrease in the amount of seizures they usually experienced.

So much so that they are actually a part of a case study.



At the very least...even tho that person has epilepsy, they still trip and work with psychedelics in full doses and they do not experience any seizures from psychedelics/tripping :shrug: .





-OM

.


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Offline330ci
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Registered: 11/22/19
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Re: Microdosing and seizures [Re: openmind]
    #26387995 - 12/18/19 01:33 AM (4 years, 1 month ago)

idk If I were prone to having seizures I wouldn't touch them, I've seen too many people seiz out at concerts and shit. I actually snuck into the vip section of a show while someone was getting carried out by the guards while they were having a seizure, I usually am a "send it" kinda guy, but in this case, i'd very much encourage you or whoever to "not send it"


if said person wants to avoid seizures, I'd look into the cbd therapies that seem to show significant improvement in the case of epileptic and i'm sure other forms of seizures. not conducting my own psudo-trial into psilocybin induced anti seizure medications.


Edited by 330ci (12/18/19 01:37 AM)


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OfflineNOUS333
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Re: Microdosing and seizures [Re: 330ci]
    #26388225 - 12/18/19 07:15 AM (4 years, 1 month ago)

Quote:

330ci said:
idk If I were prone to having seizures I wouldn't touch them, I've seen too many people seiz out at concerts and shit. I actually snuck into the vip section of a show while someone was getting carried out by the guards while they were having a seizure, I usually am a "send it" kinda guy, but in this case, i'd very much encourage you or whoever to "not send it"


if said person wants to avoid seizures, I'd look into the cbd therapies that seem to show significant improvement in the case of epileptic and i'm sure other forms of seizures. not conducting my own psudo-trial into psilocybin induced anti seizure medications.



Yeah ill probably tell them its not a good idea and to try at own risk.


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Invisibleredgreenvines
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Re: Microdosing and seizures [Re: NOUS333]
    #26388301 - 12/18/19 08:19 AM (4 years, 1 month ago)

worth a go lysergic or psilocybin
when seizures happen or don't happen - they are not predictable enough to make a policy on it for psychedelics - especially in microdoses, which are only a very tiny bit speedy like a coffee or 3.

this is not like the neural storms you can get with cocaine or speed (meth) which I would steer away from with a history of seizures.


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Invisibleopenmind
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Re: Microdosing and seizures [Re: NOUS333]
    #26388877 - 12/18/19 02:32 PM (4 years, 1 month ago)

Quote:

330ci said:
...I've seen too many people seiz out at concerts and shit. I actually snuck into the vip section of a show while someone was getting carried out by the guards while they were having a seizure.





That says absolutely nothing about psychedelics causing seizures though.

Do you know for a fact that those people you've seen at concerts were having a seizure specifically because they took LSD or some other classic psychedelic? How do you know that those people were not on something like cocaine or some sort of RC stimulant or some other drug or a mix of several different drugs? And how do you know if those people were epileptic or not? People can have seizures while not on drugs.

I go to several festivals/gatherings every year, where lots of people (practically everyone) are very high on psychedelics and/or MDMA (far more than any typical "concert")....I've never seen or heard of anyone having a seizure in the 10+ years I've been going to festivals/gatherings (except back around 2010/2011, a few people seized up because they overdosed on 25i-nbome specifically, which is a research chemical).






Quote:

NOUS333 said:

Yeah ill probably tell them its not a good idea and to try at own risk.





I don't think it's a bad idea at all :shrug: .

I mean I'd certainly let him know he's approaching it at his own risk...but it doesn't seem like a huge risk to me and there are anecdotes of LSD and psilocin lessening the occurrence of seizures for some people, basically psychedelics acting as an anti-convulsant .

If I was in the situation of being epileptic I would still continue to work with psychedelics :shrug:...I would just approach cautiously and have someone around when ever I trip. Unless I started to experience seizures when I trip and it was obvious that tripping was the trigger, I would not stop working with psychedelics.




Like I mentioned in my previous post...There is a shroomery member that has epilepsy and still trips pretty regularly with full doses and they DO NOT experience any seizures, the contrary actually as it seems to help lessen the occurrence of seizures for them and their normal "triggers" do not trigger seizures.


Here are several quotes from em' on the topic>>>>>

Quote:

Lophophora said:
Ok so last night I was informed by my wife (a behavioural neuroscientist) that she is working with a prominent behavioural scientist with an extensive and respected background in psychology (not naming for obvious reasons, he's American) to write a case study on my use of LSD as an anticonvulsant or antiepileptic drug (AED). He has a friend in MAPS that they are submitting it to.

Moreover, it could help to identify the actual factors triggering the seizures and redirect the electricity or such just my thoughts on this one.


This accidental discovery came when I decided to begin tripping again after developing epilepsy as a result of brain damage, having upwards of 200 seizures a day. I take two standard AEDs (phenytoin sodium and oxcarbazapine) and cannabis which I responded to reasonably well but was still having nearly 100 seizures a week, after taking the acid I had no seizures for an entire week and dosing 10mcg via ethanolic tincture has served to cut clusters and even end active seizures within 10 minutes. I generally have seizures starting as focal which move into complex partials (look sort of psychotic and extremely violent) and ultimately unstopped ending in generalized (tonic-clonic and drop).






Quote:

Lophophora said:
I am an epileptic psychonaut, that is I continue to explore my consciousness via the use of psychedelic compounds and meditation.....

,....Now I know this will sound irresponsible but I never stopped my psychedelic use, I saw no reason to stop as this has been the most difficult period of my life to date I frequently felt like I've been hit by a train, crippled by depression and a period of agoraphobia (fear of a seizure in public in my case), and having absolutely no short term memory for nearly a year. I have the seizures mostly controlled via diet, two meds (phenytoin 5x daily and phenobarb as a rescue), cannabis and LSD.....

That's right, I use microdoses of LSD as an AED. If I start having breakthrough seizures I will drop 10ug and 80% of the time it will stop the seizures from clustering while still allowing me to be functional which phenobarb will not. Not entirely sure what action of LSD does this but it's been a surprisingly reliable discovery for myself without having to resort to sleeping for the next 6+ hours.





Quote:

Lophophora said:
....I can drop acid and subject myself to things that consistently trigger my seizures and I'll be completely seizure free, like I won't even have any auras or anything for the entire duration of the trip so something is happening.





Quote:

Lophophora said:
In my case I noticed total relief from seizures during lysergamide trips so I tried microdosing, and had slightly reduced seizures but not significant however if I'm taking over 50mcg I'll have absolutely none and yeah my wife has spoken to a scientist at MAPS about this and we're currently doing a case study maybe there can be some lysergamide derived anticonvulsant that builds less tolerance and doesn't impair functioning (at least any more than standard AEDs) with fewer side effects.









-OM

.


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