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OfflineNorthernerM
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Neurogenesis and repair of damaged brains calls and pathways with psychedelics? * 3
    #26358357 - 12/03/19 04:24 AM (4 years, 1 month ago)

I've been thinking about this recently. So here's a few questions I thought of that I hope some people here can answer, maybe even some with anecdotes and/or first hand experience.

How effective are psychedelics for repairing damaged brains to you think?

Whether the damage has been chemically induced, like for example by alcohol abuse, or by an actual physical injury would this have a significant effect on the possibility of healing effects?

Which psychedelics would be most effective for stimulating repair and rewiring to heal damaged brains?

What sort of dosage and dosage schedule would be most effective for reaping the positive neural effects?

Has anyone seen any actual studies on these effects?

Thank you shroomy people  :peace:


--------------------
The nearest we ever come to knowing truth is when we are witness to paradox.


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OfflineCujllickduo
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Northerner]
    #26358391 - 12/03/19 05:08 AM (4 years, 1 month ago)

:whathesaid:


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OfflineVP123
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Cujllickduo]
    #26358516 - 12/03/19 06:31 AM (4 years, 1 month ago)

There have been some studies out there. Mostly with animals that show some limited potential for neurogenesis (limited because only certain regions of the brain show the effect). Because of the prohibition the available research data is limited.

Here is a link to an interesting analysis to what has been done in this field

https://www.psymposia.com/magazine/do-psychedelics-trigger-neurogenesis-heres-what-we-know/

As new research emerges, we should keep in mind that the published research tends to focus on the successful results obtained in the lab more than the failures one often has to work through when doing research.


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InvisiblefeeversM
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: VP123] * 3
    #26358578 - 12/03/19 07:05 AM (4 years, 1 month ago)

I have lots of thoughts, but the research on humans just isn't there yet.

They do increase neurogenesis by their activity on 2a receptors and triggering bdnf release, but that doesn't automatically equate into anything functionally noticeable. It just means it triggers nerve growth... somewhere. My gut tells me it's doing something useful, and by the research that seems probable, but we don't know yet, and don't know the most effective regimens and whether any gains are long term.

When an area of the brain is damaged, often over time other areas begin adapting to take over the role of the damaged area. In theory psychedelics could increase that ability due to the way they increase communication between brain areas through new pathways, helping to more quickly compensate. With repetition, those pathways of communication could grow stronger and solidify.

The reseaech is promising for sure, but too early to know exactly what's going on and how to do it right. There's a new app microdose.me that's designed to get some of this data on how different microdosing regimens effect cognition and mental health over time, so those results will be interesting.

Also lions mane is a non-psychedelic mushroom that's been studied for years for its neurogenesis properties, and would seemingly go well with any psychedelic neurogenesis routine.
https://www.ncbi.nlm.nih.gov/m/pubmed/24266378/


Edited by feevers (12/03/19 07:30 AM)


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InvisiblefeeversM
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: feevers] * 3
    #26358609 - 12/03/19 07:27 AM (4 years, 1 month ago)

Kinda funny to see things that some of us have always considered "mind expanding" to in a way literally/physically be just that.


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OfflineSocrateshroom
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: feevers] * 1
    #26358992 - 12/03/19 12:12 PM (4 years, 1 month ago)

Quote:

feevers said:
I have lots of thoughts, but the research on humans just isn't there yet.

They do increase neurogenesis by their activity on 2a receptors and triggering bdnf release, but that doesn't automatically equate into anything functionally noticeable. It just means it triggers nerve growth... somewhere. My gut tells me it's doing something useful, and by the research that seems probable, but we don't know yet, and don't know the most effective regimens and whether any gains are long term.

When an area of the brain is damaged, often over time other areas begin adapting to take over the role of the damaged area. In theory psychedelics could increase that ability due to the way they increase communication between brain areas through new pathways, helping to more quickly compensate. With repetition, those pathways of communication could grow stronger and solidify.

The reseaech is promising for sure, but too early to know exactly what's going on and how to do it right. There's a new app microdose.me that's designed to get some of this data on how different microdosing regimens effect cognition and mental health over time, so those results will be interesting.

Also lions mane is a non-psychedelic mushroom that's been studied for years for its neurogenesis properties, and would seemingly go well with any psychedelic neurogenesis routine.
https://www.ncbi.nlm.nih.gov/m/pubmed/24266378/




:whathesaid:

From my own anecdotal data, Psilocybin has returned to me my memories of my past which, for a long time, seemed lost. Now whether that is because they are neuro-regenerative or because they helped undo blockages from psychological trauma is unknown to me.

If you consider psychological trauma to be "damage" then there seems to be more than enough of a sample size to prove that it does, indeed, aid in healing. Furthermore, it alleviates depression and anxiety (especially in micro doses). These effects are long lasting and some may even be permanent.


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OfflineDJ Ed
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Northerner]
    #26359015 - 12/03/19 12:25 PM (4 years, 1 month ago)

All of the above!

What a fantastic question, and what excellent responses guys. Give yourselves a pat on the back.

I watched a Joe Rogan podcast with Paul Stamets, about 1 to 2 years ago (not the one that came out a couple of weeks back). So approximately 2017.

In it he discusses the neurogenesis properties of pysilocybin mushrooms, but also about Lions Mane mushrooms.

Once these are legal again hopefully the research will expand exponentially.

From personal experience, using mushrooms for depression reduction, I have noted a few things:

1. I definitely feel like a decent 3.5g+ dried dose wipes and resets my brain. All the negative thinking patterns are wiped, and for up to a week, things go over my head and don’t phase me. I am taking 3.5+ doses at fortnightly intervals.

2. My depression has reduced massively. I no longer hit rock bottom, and when I do become low, I can think my way out of it much more quickly and easily.

3. We humans are genetically approx. 70% mushroom. I recently posted some thoughts from a recent trip, questioning whether that feeling of oneness is akin to a mycelial network. Who knows, one day we may have scientific data....

Thanks all for posting.

And hey, northerner; whereabouts in the north? I’m Lancs. By all means pm me.

Take care y’all,
DJ Ed


--------------------
“It’s like when you see a mountain lion,” he suggested. “If you run, it will chase you. So you must stand your ground.”
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Offlinetrippleblack
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: DJ Ed]
    #26359028 - 12/03/19 12:36 PM (4 years, 1 month ago)

No way to know if it was the mushrooms..

but i had brain damage from carbon monoxide poisoning..  didn't think i would ever heal from the chronic poisoning. it was life threatening. The constant use of psychedelics especially mushrooms makes me think it repaired the portions of my brain which became inactive from carbon monoxide.

i still get headaches when exposed to low levels of carbon monoxide, but its at a progressive reduction of pain by about 80 - 90%


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Offlineindividualist
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: trippleblack]
    #26359205 - 12/03/19 02:16 PM (4 years, 1 month ago)

These are strong arguments for microdosing, but not necessarily for full on tripping.


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Offlinepixelpopper
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Socrateshroom]
    #26359224 - 12/03/19 02:23 PM (4 years, 1 month ago)

Quote:

Socrateshroom said:
From my own anecdotal data, Psilocybin has returned to me my memories of my past which, for a long time, seemed lost. Now whether that is because they are neuro-regenerative or because they helped undo blockages from psychological trauma is unknown to me.

If you consider psychological trauma to be "damage" then there seems to be more than enough of a sample size to prove that it does, indeed, aid in healing. Furthermore, it alleviates depression and anxiety (especially in micro doses). These effects are long lasting and some may even be permanent.




Psychological trauma causes brain damage in kids in that it actually shuts down certain areas from developing. So trauma can cause literal brain damage, as well as psychological


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OfflineKorean Jesus
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: pixelpopper]
    #26359534 - 12/03/19 04:31 PM (4 years, 1 month ago)

I have no doubt that psychedelics are neurogenic, as they change the way one appreciates many things in life. Their neurogenic effects are probably limited only to these regions, but I could definitely see someone with brain damage that affects their sense of smell or their ability to connect different abstract ideas being helped by them.


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OfflineSocrateshroom
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: pixelpopper]
    #26360591 - 12/04/19 08:18 AM (4 years, 1 month ago)

Quote:

pixelpopper said:
Quote:

Socrateshroom said:
From my own anecdotal data, Psilocybin has returned to me my memories of my past which, for a long time, seemed lost. Now whether that is because they are neuro-regenerative or because they helped undo blockages from psychological trauma is unknown to me.

If you consider psychological trauma to be "damage" then there seems to be more than enough of a sample size to prove that it does, indeed, aid in healing. Furthermore, it alleviates depression and anxiety (especially in micro doses). These effects are long lasting and some may even be permanent.




Psychological trauma causes brain damage in kids in that it actually shuts down certain areas from developing. So trauma can cause literal brain damage, as well as psychological





I figured as much but I'm not a neurologist so I didn't want to assume so. But yes, I know that from the psychological trauma I've had parts of my brain that either "under-developed" or developed "incorrectly" manifesting in various neuroses. Mushrooms have and continue to help me correct these problems. (But it isn't immediate and life changes must be made in conjunction with the substance. I would definitely say that shrooms catalyze neurological and psychological healing.)


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Offlinepixelpopper
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Socrateshroom] * 1
    #26360975 - 12/04/19 12:12 PM (4 years, 1 month ago)

Quote:

Socrateshroom said:
I would definitely say that shrooms catalyze neurological and psychological healing.




In this recent podcast interview I just listened to with an underground psychedelic therapist, he comments how shrooms are unique in therapy, compared to LSD, because they somehow act on their own to heal psychological trauma - as if the mushroom is doing its own thing totally apart from the user. He mentions how mushrooms will naturally produce whatever is needed for healing, including even physical reactions like bodily shaking - I've read a great book about healing trauma and its origins, and one of the key points it makes is that you can avoid repressing/internalizing trauma when experiencing a traumatic event, if you allow your body to shake it out in convulsions. So it was interesting to hear this point about mushrooms sometimes healing trauma by producing this same bodily reaction (that book being In an Unspoken Voice: How the Body Releases Trauma and Restores Goodnessby Peter A. Levine )


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OfflineSocrateshroom
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: pixelpopper]
    #26361008 - 12/04/19 12:34 PM (4 years, 1 month ago)

Quote:

pixelpopper said:
Quote:

Socrateshroom said:
I would definitely say that shrooms catalyze neurological and psychological healing.




In this recent podcast interview I just listened to with an underground psychedelic therapist, he comments how shrooms are unique in therapy, compared to LSD, because they somehow act on their own to heal psychological trauma - as if the mushroom is doing its own thing totally apart from the user. He mentions how mushrooms will naturally produce whatever is needed for healing, including even physical reactions like bodily shaking - I've read a great book about healing trauma and its origins, and one of the key points it makes is that you can avoid repressing/internalizing trauma when experiencing a traumatic event, if you allow your body to shake it out in convulsions. So it was interesting to hear this point about mushrooms sometimes healing trauma by producing this same bodily reaction (that book being In an Unspoken Voice: How the Body Releases Trauma and Restores Goodnessby Peter A. Levine )




Radical! Thank you for the new book suggestion :heart: I've been meaning to dive into the psychotherapy of healing traumas.

But I would definitely agree on this notion that mushrooms "do their own thing". I think they can be directed but their healing power has always come from left field when imbibing. Not that I wasn't expecting or wanting the healing to occur but what I wanted to heal was usually not what I was shown needed healing.

I wonder if this power can in fact be directed with utmost prejudice to obliterate the neuroses and traumas that ail me.


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OfflineNorthernerM
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Socrateshroom]
    #26361739 - 12/04/19 07:54 PM (4 years, 1 month ago)

Thanks heaps guys for your valuable input, it's given me loads to think about and more leads to follow and read about than I anticipated. The subject has opened up before me like a chasm.

I also wondered how the every switch on, all lights lit, trip like DMT breakthrough compares to a mid range, warping shapes and unusual thought, mushroom trip. Both of them are clearly lighting up different pathways in the brain and especially when combined with MAOIs last a significant amount of time and can have an extended effect on mood. Whether or not these modes of thinking and newly burned pathways in the brain continue to fire is a question that itches.

I've got my anecdotes, things that I think about how they effect me. But I'm unable to tell truth from my perceived reality with this.


--------------------
The nearest we ever come to knowing truth is when we are witness to paradox.


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Invisiblenooneman
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Northerner]
    #26361752 - 12/04/19 08:02 PM (4 years, 1 month ago)

I don't think they have much of an impact on the growth of new neurons.

But more broadly speaking, I think that LSD and psilocybin might allow the brain to route around damage and better reorganize following damage. The main thing that both psychedelics have been proved to do in the brain is to make tons of areas of the brain that don't normally talk suddenly start talking to each other. That just has to be an advantage in a case where someone has damage.

It might even be possible over a long enough period of time for new connections and pathways to form between distant regions that were separated by the damage as a result of the psychedelics allowing completely different regions to talk to each other.

But that's all just uneducated armchair speculation. What we need are actual scientific studies into people with brain damage. The problem is the moral and ethical problems involved in giving a person with brain damage psychedelics. You might temporarily make things worse for them, who knows what kind of things might happen in the mind of someone brain damaged who takes LSD.


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OfflineNorthernerM
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: nooneman]
    #26361880 - 12/04/19 09:39 PM (4 years, 1 month ago)

I'm pretty sure there's plenty of people who have suffered brain damage by various means that would be more than happy to sign away liability to be part of a study that can potentially show promise in restoring parts of what they have lost.

When we observe people who have lost particular senses we see that the ones that they have left often gain ability far in excess of average. Whether this is just through practice and attunement or whether or not their brains have compensated in ways to make them increasingly capable it would be really interesting to know.

When we look at someone who has suffered brain matter death from poisoning or concussion (just for example) it may be that the brain compensates and actually builds itself stronger around those damaged areas, in excess of average performance. In this way being both rewiring and neurogenesis simultaneously, of newly found neural pathways.


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InvisiblefeeversM
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Northerner]
    #26362738 - 12/05/19 10:39 AM (4 years, 1 month ago)

This study was with single dose 5-meo-dmt

"Our findings show that 5-MeO-DMT affects neurogenesis and this effect may contribute to the known antidepressant properties of DMT-derived compounds."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131656/


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OfflinePrimalSoup
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Northerner] * 1
    #26363354 - 12/05/19 04:33 PM (4 years, 1 month ago)

Quote:

Northerner said:
I've been thinking about this recently. So here's a few questions I thought of that I hope some people here can answer, maybe even some with anecdotes and/or first hand experience.

How effective are psychedelics for repairing damaged brains to you think?

Whether the damage has been chemically induced, like for example by alcohol abuse, or by an actual physical injury would this have a significant effect on the possibility of healing effects?

Which psychedelics would be most effective for stimulating repair and rewiring to heal damaged brains?

What sort of dosage and dosage schedule would be most effective for reaping the positive neural effects?

Has anyone seen any actual studies on these effects?

Thank you shroomy people  :peace:




IME they are very effective at repair of trauma induced damage.  They are also good for building new sorts of useful brain functions and just generally rewiring existing functions.  I only have experience with mushrooms.  The effects seem to go along with high dosages but I can't be 100% sure of that since I haven't successfully microdosed while working with either of those scenarios.

This poses problems for actual studies because they don't like to send people around the bend in clinical settings, SFAIK.  And I can't speak for what ancillary compounds may be involved in the process beyond psilocin and psilocybin.

Oh, and speaking from experience, the gains are all long term.  The things above are explained for me by neurogenesis and neuroplasticity.  Both of these can be extremely useful depending on what you're trying to do and how dedicated you are about doing it.  One trip isn't the ticket, many trips are. :awesomenod:


--------------------

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OfflineHappinessfeeling
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: PrimalSoup]
    #26365423 - 12/06/19 04:26 PM (4 years, 1 month ago)

Don't be such a drug addict.


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OfflinePrimalSoup
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Happinessfeeling]
    #26365499 - 12/06/19 05:06 PM (4 years, 1 month ago)

:laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2::laugh2:


--------------------

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OfflineLophophora
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: PrimalSoup]
    #26365829 - 12/06/19 08:02 PM (4 years, 1 month ago)

Not sure about the neurogenesis repairing anything but I can drop acid and subject myself to things that consistently trigger my seizures and I'll be completely seizure free, like I won't even have any auras or anything for the entire duration of the trip so something is happening.


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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Lophophora]
    #26365959 - 12/06/19 10:06 PM (4 years, 1 month ago)

This is another interesting thing. I've heard that a few times from people.  :awesomenod:

I have a friend with familial peripheral neuropathy that's pretty bad and he's interested in trying mushrooms to see if it provides some relief.  Either short term or long term would be welcome.  And I'm growing again currently so pretty soon we'll find out.  I figure microdoses are probably the best idea, but I'll lay the dosages out for the PE I'll provide and let him try whatever he likes.


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OfflineNorthernerM
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: PrimalSoup]
    #26366189 - 12/07/19 02:19 AM (4 years, 1 month ago)

My tinnitus disappears on both mushrooms and lsd also. On sub-breakthrough doses of dmt it becomes very loud, often like clanging bells or chains, but if I break through it's silence. Glorious silence.


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OfflineLophophora
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: PrimalSoup]
    #26366193 - 12/07/19 02:22 AM (4 years, 1 month ago)

In my case I noticed total relief from seizures during lysergamide trips so I tried microdosing, and had slightly reduced seizures but not significant however if I'm taking over 50mcg I'll have absolutely none and yeah my wife has spoken to a scientist at MAPS about this and we're currently doing a case study maybe there can be some lysergamide derived anticonvulsant that builds less tolerance and doesn't impair functioning (at least any more than standard AEDs) with fewer side effects.


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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Northerner]
    #26366197 - 12/07/19 02:24 AM (4 years, 1 month ago)

Interesting, DMT is fucking loud for me sub breakthrough everything sounds so warped and distorted and broken through I'm surprised I'm not deaf from that shit.


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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Lophophora]
    #26366376 - 12/07/19 07:27 AM (4 years, 1 month ago)

stop being such a drug addict.
Drugs aren't the solution to your problems.


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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Happinessfeeling]
    #26366379 - 12/07/19 07:32 AM (4 years, 1 month ago)

Quote:

Happinessfeeling said:
stop being such a drug addict.
Drugs aren't the solution to your problems.




our problems are created by the bag of drugs that is our body and brain


Edited by feevers (12/07/19 03:39 PM)


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OfflineNorthernerM
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Happinessfeeling]
    #26366796 - 12/07/19 12:03 PM (4 years, 1 month ago)

Quote:

Happinessfeeling said:
stop being such a drug addict.
Drugs aren't the solution to your problems.



Should people seek help with Santa rather?
____________

Dear Santa,
For Christmas can you please reverse the brain damage I have experienced?
I was going to look more closely at a scientific approach using psychedelics as there is considerable evidence to suggest they may be able to assist if used correctly, but drugs are bad m'kay.
Love
Katie. X


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The nearest we ever come to knowing truth is when we are witness to paradox.


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OfflineLophophora
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Happinessfeeling]
    #26366861 - 12/07/19 12:38 PM (4 years, 1 month ago)

You referring to me as an addict? Only things I'm addicted to are caffeine and nicotine, and I'm tapering down my nicotine because I was told not to stop cold turkey by my doctors because withdrawal throws off homeostasis which is a massive seizure trigger. And in my case yeah drugs kinda are the solution to my problems since my brain is literally trying to kill me...just between September and October I went into the hospital in nonconvulsive status nearly 20 times and at the end of October I went into convulsive status epilepticus 6 times in one week, I have a brain injury and I can't just will that away as much as I wish I could. I have no choice but to take 2,750mg Keppra, 1,500mg Trileptal, 15mg Clobazam, 900mg ashwagandha, and 1mg of lorazepam daily when I found that LSD stopped my seizures completely I jumped on it, maybe the underlying mechanism can help to develop better anticonvulsants for drug resistant epilepsies. I'm reliant on drugs to live not addicted.


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Offlinepixelpopper
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Lophophora]
    #26366905 - 12/07/19 12:58 PM (4 years, 1 month ago)

dude is either a dumbass or a troll

only 2 posts in this thread have been clearly meant to provoke

either way :shrug:


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OfflineLophophora
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: pixelpopper]
    #26366929 - 12/07/19 01:04 PM (4 years, 1 month ago)

Shit didn't realize this was the second page, I got here late. Yeah, I'd have to agree with you pixel


Edited by Lophophora (12/07/19 01:05 PM)


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OfflineNorthernerM
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Lophophora] * 1
    #26366995 - 12/07/19 01:29 PM (4 years, 1 month ago)

You don't need to defend yourself Lophophora.

If anything HF needs to explain why he keeps pointing the addict blame and shame stick in this thread, the topic is not about about addictive drugs and it is not about drug abuse either. He's just acting like a fuckhead.

Anyhow...

Reading more about this topic I've been surprised how much research has actually been and is currently being done. It's somewhat given me hope that I can overcome a lot of the difficulties I experience due to my own brain problems. Short term results with low and regular dosing of psychedelics have given me relief and returned some of my previous mental acuity. I have questions about the sustainability of such a regimen though and also am hesitant to eat psychedelics at all times. It may sound funny to some folks, but I rarely want to take psychedelics. I'm not in a romance period and I don't find psychedelics particularly wonderful at the moment. But the ongoing positive effects are noticeable. I was supposed to dose this morning but unable to bring myself to do it, maybe later in the day I guess. A journal to map how these things effect me might be in order.


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OfflineLophophora
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Northerner]
    #26367094 - 12/07/19 02:26 PM (4 years, 1 month ago)

Totally get the not particularly wonderful in the moment bit, I trip frequently myself but almost any of the trips that have helped me have been complete and utter hell to go through though in the end I survived and had a new appreciation for life and a new outlook/perspective.


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OfflineLophophora
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Northerner]
    #26367110 - 12/07/19 02:39 PM (4 years, 1 month ago)

And say taking LSD for my seizures, no it's not sustainable but if there's something I really need or want to do where I WILL encounter triggers I'm on 50-100mcg, but if the underlying mechanism is figured out one drugs that don't have the same tolerance issue or impairment of being in a psychedelic state could be created...though the anticonvulsants currently available cause impaired cognition, bone mineral depletion, short and long term memory loss, sedation, long term fatigue, electrolyte imbalances, liver problems, with the exception of Keppra (levetiracetam) and Brivlera (brivaracetam) which cause bone mineral loss, rage, psychosis, agitation, anaphylaxis without allergy, sudden organ failure. Used to be on Dilantin (phenytoin sodium) and would literally walk across the house to do something and have no clue what I was doing or how I got there.


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OfflinePrimalSoup
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Happinessfeeling] * 2
    #26367196 - 12/07/19 03:32 PM (4 years, 1 month ago)

Quote:

Happinessfeeling said:
stop being such a drug addict.
Drugs aren't the solution to your problems.




Bring something to the thread or STFU.  Adults are talking here. :lamastare:


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OfflineHappinessfeeling
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: PrimalSoup]
    #26368755 - 12/08/19 10:10 AM (4 years, 1 month ago)

That's funny, I'm probably older than you are.
But anyways, I'll reiterate what I said earlier but in a different way.
Looking to drugs to solve your degenerative neurological condition is absolutely not the answer.
I know that people want to hail psychedelics as cure alls and the answer to a million and one problems, but psychedelics are not panaceas.
the more sensible answer is usually the correct one.
In this case, changing diet, exercising, meditating, hatha yoga practice, creative hobbies, these things will cure your damaged brain cells, not more drugs.
I hope I made my point clear now.


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OfflinePrimalSoup
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Re: Neurogenesis and repair of damaged brains calls and pathways with psychedelics? [Re: Happinessfeeling] * 2
    #26368970 - 12/08/19 12:22 PM (4 years, 1 month ago)

That's funny, hmm?  I'm 64 so I really doubt you're "older than me".

Age doesn't bring wisdom, but you've made it obvious you don't express yourself well and are painfully ignorant of what's actually being discussed in this thread, and the subject of medical research.

But if you'd said that earlier rather than complain about "drug addicts" you wouldn't earn the animosity that you received and feel the need to defend yourself earlier.


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if you stand too close to the machine it'll start to eat you
Primal's simple tested teks and projects: :awesomenod: Wheat Prep 2.0  Acidic Tea Tek  Potency Project! 


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