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Mushrooms, Mycology and Psychedelics > The Psychedelic Experience
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Microdosing plus antidepressants
    #26142807 -

Does anyone microdose while still taking antidepressants (SSRI's)? What meds do you take? What do you microdose? Does one affect the other? Is microdosing still effective while in SSRI's? Any and all info would be great.

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Re: Microdosing plus antidepressants [Re: MrDudeMan2222]
    #26142914 -

Not a great idea.

SSRI's have a cross tolerance to actives and there could be aggression frustration issues.  SSRI's already make some people aggressive and violent.


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"in sterquiliniis invenitur in stercore invenitur"

In filth it will be found in dung it will be found

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Re: Microdosing plus antidepressants [Re: Morel Guy]
    #26143116 -

Morel Guy said:
Not a great idea.

SSRI's have a cross tolerance to actives and there could be aggression frustration issues.  SSRI's already make some people aggressive and violent.


This thread says it all, Mate.


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LSD Dosage Effects - Tolerance - FULL Version - Bluelight.org:alert:  :alien: :mushroom2:

SSRis + Psychedelics

Edited by heatlessbbq (08/19/19 03:55 PM)

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Re: Microdosing plus antidepressants [Re: heatlessbbq]
    #26143706 -

Quote:
More information found here <-------- CLICK HERE




Quote:
More information found here <-------- CLICK HERE


Edited by heatlessbbq (08/19/19 10:34 PM)

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Re: Microdosing plus antidepressants [Re: heatlessbbq]
    #26144213 -

I'm primarily referring to microdosing.

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Re: Microdosing plus antidepressants [Re: MrDudeMan2222]
    #26144216 -

Ssri are pretty much a microdose.


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"in sterquiliniis invenitur in stercore invenitur"

In filth it will be found in dung it will be found

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Re: Microdosing plus antidepressants [Re: Morel Guy]
    #26144218 -

It doesn't matter what dosage.

SSRIs mixed with psychedelic substances is dangerous. Period.


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LSD Dosage Effects - Tolerance - FULL Version - Bluelight.org:alert:  :alien: :mushroom2:

SSRis + Psychedelics

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Re: Microdosing plus antidepressants [Re: heatlessbbq] * 2
    #26144255 -

SSRIs don't make you trip longer or stronger, they dull the effects to almost non present.

Dosing while on a SSRI is a waste in most cases. No matter if you take a micro dose or a normal dose, you won't feel much.
With SSRIy you have to take abnormal high doses to get trippy, still dulled effects. -> A waste.

-


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.. long distance trip / are you shpongled? / ELDER / TUBER / Jordso / IAH / Sleeping Pandora ... / Thurnin / OPETH ...
.. essential psychedelic guide, by D.M.Turner
.. Tihkal .. / .. Pihkal .. / .. Psilohuasca ..

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Re: Microdosing plus antidepressants [Re: Pandemoon]
    #26145334 -

Pandemoon said:
SSRIs don't make you trip longer or stronger, they dull the effects to almost non present.

Dosing while on a SSRI is a waste in most cases. No matter if you take a micro dose or a normal dose, you won't feel much.
With SSRIy you have to take abnormal high doses to get trippy, still dulled effects. -> A waste.


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Re: Microdosing plus antidepressants [Re: nooneman]
    #26145368 -

What about body chemistry and behavior?


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LSD Dosage Effects - Tolerance - FULL Version - Bluelight.org:alert:  :alien: :mushroom2:

SSRis + Psychedelics

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Re: Microdosing plus antidepressants [Re: heatlessbbq]
    #26145373 -

SSRIs are cross tolerant with psychedelics. You know how you can get tolerance from taking mushrooms or LSD too often? SSRIs cause the same tolerance because they affect the serotonin receptors.

Imagine how much tolerance a person would build if they took 100ug of LSD every day. After a few weeks, they wouldn't feel almost anything.

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Re: Microdosing plus antidepressants [Re: Pandemoon]
    #26145415 -

SSRIs with psychs are not dangerous. My wife takes an SSRI and we trip together from time to time. She has a reduced sensitivity to them, but they still work for her.


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We are the music makers, the dreamers of dreams.

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Re: Microdosing plus antidepressants [Re: nooneman]
    #26145474 -

nooneman said:
SSRIs are cross tolerant with psychedelics. You know how you can get tolerance from taking mushrooms or LSD too often? SSRIs cause the same tolerance because they affect the serotonin receptors.

Imagine how much tolerance a person would build if they took 100ug of LSD every day. After a few weeks, they wouldn't feel almost anything.



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LSD Dosage Effects - Tolerance - FULL Version - Bluelight.org:alert:  :alien: :mushroom2:

SSRis + Psychedelics

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Re: Microdosing plus antidepressants [Re: heatlessbbq]
    #26145605 -

Not all SSRi's are the same, many target different receptor groups, and not all people are the same chemically so results will vary.

Apart from the danger of wasting perfectly good drugs there's virtually no increased danger by mixing the two.

Studies on possible interactions have shown a negligible negative reaction possibility, so low it could be statistical anomaly.

Edit: Taking high doses of SSRIs and psychedelics could be an issue though. It's just in controlled doses that there is very little chance of any harm. The effects of the substances are after all not synergistic.


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We are the music makers, the dreamers of dreams.

Edited by Northerner (08/21/19 04:53 AM)

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Re: Microdosing plus antidepressants [Re: Northerner]
    #26145634 -

which ssri is your wife using?


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:brainfart: _ :finger:

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Re: Microdosing plus antidepressants [Re: redgreenvines]
    #26145643 -

Escitalopram.


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We are the music makers, the dreamers of dreams.

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Re: Microdosing plus antidepressants [Re: Northerner]
    #26145763 -

Northerner said:
Not all SSRi's are the same, many target different receptor groups, and not all people are the same chemically so results will vary.

Apart from the danger of wasting perfectly good drugs there's virtually no increased danger by mixing the two.

Studies on possible interactions have shown a negligible negative reaction possibility, so low it could be statistical anomaly.

Edit: Taking high doses of SSRIs and psychedelics could be an issue though. It's just in controlled doses that there is very little chance of any harm. The effects of the substances are after all not synergistic.


SSRIs stands for Selective serotonin reuptake inhibitors.

Serotonin is NOT something to be fucking with.
And yes, Northerner... They ALL target the same receptor group, actually.


--------------------
LSD Dosage Effects - Tolerance - FULL Version - Bluelight.org:alert:  :alien: :mushroom2:

SSRis + Psychedelics

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Re: Microdosing plus antidepressants [Re: heatlessbbq]
    #26145797 -

As well as they can be synergistic.  It depends at what point in ssri exposure the psycadelic is taken.  First two weeks I know for experience that it's a strong trip.

5ht2a is serotonin hence the 5ht.  That is where most controlled rec drugs that cause hallucinations function.


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"in sterquiliniis invenitur in stercore invenitur"

In filth it will be found in dung it will be found

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Re: Microdosing plus antidepressants [Re: Morel Guy] * 1
    #26146411 -

heatlessbbq said:
SSRIs stands for Selective serotonin reuptake inhibitors.

Serotonin is NOT something to be fucking with.
And yes, Northerner... They ALL target the same receptor group, actually.


Yes I know what they are exactly how they work. Different SSRIs have varying affinities for different receptors within the group also. 2 minutes of Google Fu can confirm that for you.

Many drugs fuck with seratonin, there is a chance of seratonin syndrome just by taking mdma or other amphetamines, or even an SSRI by itself. Everyone's chemistry is different.

Morel Guy said:
As well as they can be synergistic.  It depends at what point in ssri exposure the psycadelic is taken.  First two weeks I know for experience that it's a strong trip.



Didn't know that.

Taking an SSRI even a year after taking psychedelics can lead to strong flashbacks as well. It's a weird relationship between the two.


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We are the music makers, the dreamers of dreams.

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Re: Microdosing plus antidepressants [Re: Northerner]
    #26147551 -

:yinyangtrip:

A lot of mixed information in the bag. :nyan:


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LSD Dosage Effects - Tolerance - FULL Version - Bluelight.org:alert:  :alien: :mushroom2:

SSRis + Psychedelics

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Mushrooms, Mycology and Psychedelics > The Psychedelic Experience
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