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OfflineOOISI
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Dying patients to be given psilocybin * 1
    #25907096 - 03/31/19 01:47 AM (2 months, 18 days ago)

The controversial trial aims to reduce anxiety about death among terminally ill patients.
Updated Updated 16 January
By Maani Truu
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Dying patients at a Melbourne hospital will be treated with magic mushrooms in a controversial trial aimed at reducing anxiety about death among terminally ill patients.

Under the St Vincent's Hospital trial, which has taken more than a year to be approved by the ethics committee and federal and state authorities, the 30 patients will be treated in April this year.

Clinical psychologist Dr Margaret Ross said patients would be given a single dose of synthetic psilocybin, the psychoactive ingredient in mushrooms, which can unlock a section of the brain, giving people an altered outlook on their situation as they approach death.

One dose can last for six months or more.

Late last year, researchers from Johns Hopkins University in the United States found that a majority of people suffering from cancer-related anxiety or depression had significant relief after taking a single, large does of psilocybin.

Six months after the study, 80 per cent of the 51 patients analysed showed significant decreases in depressed mood and anxiety, while about 60 per cent showed symptoms in the normal range.

The trial also found that participants had an increased quality of life, with 83 per cent reporting increases in wellbeing and 67 per cent reporting that the experience was one of the top five meaningful experiences in their lives.

During the trial, the drug was only given in controlled environments and under the observation of two clinically-trained monitors and the researchers did not recommend using the drug in an outside setting.

According to St Vincent's Hospital, three in every 10 palliative care patients can experience extreme distress in their final months.

https://www.sbs.com.au/news/dying-patients-to-be-given-magic-mushrooms-at-melbourne-hospital


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Edited by Alan Rockefeller (04/01/19 11:07 PM)


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OfflineKonyap

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Re: Dying patients to be given Psilocybes [Re: OOISI]
    #25907122 - 03/31/19 02:28 AM (2 months, 18 days ago)

It goes on and on forever man:yesnod:


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OfflineMikeTesserect
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Re: Dying patients to be given Psilocybes [Re: OOISI]
    #25907225 - 03/31/19 05:33 AM (2 months, 18 days ago)

U are just returning to prenatal nothingness. how fucking hard is it lol


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Offlinetacodude
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Re: Dying patients to be given Psilocybes [Re: MikeTesserect]
    #25907345 - 03/31/19 08:31 AM (2 months, 18 days ago)

I really think they would be better off using LSD for this...


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Re: Dying patients to be given Psilocybes [Re: tacodude]
    #25907348 - 03/31/19 08:34 AM (2 months, 18 days ago)

Quote:

One dose can last for six months or more




Poorly worded much...


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OfflineO_Dweeds
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Re: Dying patients to be given Psilocybes [Re: tacodude]
    #25908005 - 03/31/19 02:52 PM (2 months, 18 days ago)

LSD is incredibly similar to intense, long duration stimulants in addition to its psychoactive effects. That's what is was originally developed for, and is still great for in proper dosage.(what many here would call micro-dosing). Methamphetamine like stimulation with psychoactive effects lasting 12+ hours better for a dying patient?

Nah I have to strongly disagree with you on that. Natural psilocybin is wayyy more beneficial, especially under these circumstances. And in all uses for medical benefits in my opinion.


--------------------
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  Dave Chappelle

"There ain't no revolution, only evolution, but every time I'm in Georgia I eat a peach for peace."
Gregg Allman


Edited by O_Dweeds (03/31/19 02:52 PM)


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OfflineKonyap

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Re: Dying patients to be given Psilocybes [Re: O_Dweeds]
    #25908284 - 03/31/19 05:38 PM (2 months, 18 days ago)

anyone can get fucked up on any drug they want

they probably give these people like a gram at most and they do it so much the person builds up a tolerance but they have these "hallucinations" for weeks which is really just code for dreams

people used to take 300ug in a session but you know theres a lot less chance of them freaking out if there's a real doctor in the room.
source: my father was an alcoholic


Edited by Konyap (03/31/19 05:39 PM)


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Offlinetacodude
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Re: Dying patients to be given Psilocybes [Re: Konyap]
    #25908378 - 03/31/19 06:40 PM (2 months, 18 days ago)

LSD is not like meth or a stimulant... It does have dopamine activity, but that makes it more like mescaline or other phenethylamine compounds. Really if you want to nitpick mescsline probably would work too, but I haven't experienced mescaline so I can't honestly say.


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OfflineLemonfist
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Re: Dying patients to be given Psilocybes [Re: tacodude]
    #25909042 - 04/01/19 06:39 AM (2 months, 17 days ago)

It would be so fun to take part in this research. Not as a patient, I would prefer not to die yet.


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Offlinegandalfe
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Re: Dying patients to be given Psilocybes [Re: OOISI]
    #25909457 - 04/01/19 12:07 PM (2 months, 17 days ago)

Its so great that the effects can last a whole six months.If they only live for three months it works good.If they live for 7 months they are getting scared again, so they might think of a euthanasia right at the 5 month mark.This stuff seems to mean more and more to me, as I become  like the rest of the perishing hordes of old,feeble,sick,depressed, and dying.This life cycle is great until we reach the end and start reaching for the mushrooms.


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Re: Dying patients to be given Psilocybes [Re: gandalfe]
    #25909480 - 04/01/19 12:23 PM (2 months, 17 days ago)

The whole point is a positive mindset can turn something like cancer around... It's about easing end of life anxiety to not suffer in the end and not specifically making sure they die happy. There's no reason they can't dose again


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Re: Dying patients to be given Psilocybes [Re: OOISI]
    #25909562 - 04/01/19 01:21 PM (2 months, 17 days ago)

So, are they giving 4-ho-met?


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Re: Dying patients to be given Psilocybes [Re: tyrannicalrex]
    #25909670 - 04/01/19 02:27 PM (2 months, 17 days ago)

??? Where did it say that. I'm pretty sure I remember another company working with a similar compound.


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OfflineKonyap

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Re: Dying patients to be given Psilocybes [Re: tacodude]
    #25909678 - 04/01/19 02:31 PM (2 months, 17 days ago)

No.

Isn't it like a dmt variant??


Edited by Konyap (04/01/19 02:32 PM)


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Re: Dying patients to be given Psilocybes [Re: Konyap]
    #25909774 - 04/01/19 03:23 PM (2 months, 17 days ago)

"single dose of synthetic psilocybin"


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Re: Dying patients to be given Psilocybes [Re: tyrannicalrex]
    #25909781 - 04/01/19 03:25 PM (2 months, 17 days ago)

Then that's what they're getting not otherwise it would say what psilocybin/psilocin prodrug it was


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Re: Dying patients to be given Psilocybes [Re: bodhisatta]
    #25909788 - 04/01/19 03:27 PM (2 months, 17 days ago)

Quote:

bodhisatta said:
Then that's what they're getting not otherwise it would say what psilocybin/psilocin prodrug it was



Could you please put this less cryptically.


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Re: Dying patients to be given Psilocybes [Re: tyrannicalrex] * 1
    #25909793 - 04/01/19 03:30 PM (2 months, 17 days ago)

They're getting a single dose of synthetic psilocybin" not something else otherwise it would say what that something else was instead...

Are you like a million grams per cubic centimeter?


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Re: Dying patients to be given Psilocybes [Re: bodhisatta]
    #25909799 - 04/01/19 03:33 PM (2 months, 17 days ago)

So 4-aco-dmt then?


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Re: Dying patients to be given Psilocybes [Re: tyrannicalrex] * 1
    #25909836 - 04/01/19 03:50 PM (2 months, 17 days ago)

No
4-po-ho-dmt


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OfflineO_Dweeds
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Re: Dying patients to be given Psilocybes [Re: tacodude]
    #25910655 - 04/01/19 10:55 PM (2 months, 16 days ago)

Quote:

tacodude said:
LSD is not like meth or a stimulant... It does have dopamine activity, but that makes it more like mescaline or other phenethylamine compounds. Really if you want to nitpick mescsline probably would work too, but I haven't experienced mescaline so I can't honestly say.




It's stimulation properties are most certainly equivalent in strength. Obviously it has as intense psychoactive effects as strong as the user wishes to delve into. Try sleeping even 5-6 hours after taking LSD; no dice.

If you really believe psychoactives don't give one control over your mind to allow for release of naturally produced dopamine/ serotonin, some people at minute levels some at near full control (depending on mental strength and natural levels of the individual), then you haven't explored enough.


--------------------
Never Pass Up A Good Thing

"I'd like thank god almighty, for giving everybody else so much...and me so little."
  Dave Chappelle

"There ain't no revolution, only evolution, but every time I'm in Georgia I eat a peach for peace."
Gregg Allman


Edited by O_Dweeds (04/01/19 11:03 PM)


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OfflineO_Dweeds
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Re: Dying patients to be given Psilocybes [Re: Konyap]
    #25910661 - 04/01/19 11:01 PM (2 months, 16 days ago)

Quote:

Konyap said:
anyone can get fucked up on any drug they want

they probably give these people like a gram at most and they do it so much the person builds up a tolerance but they have these "hallucinations" for weeks which is really just code for dreams

people used to take 300ug in a session but you know theres a lot less chance of them freaking out if there's a real doctor in the room.
source: my father was an alcoholic



Obviously everyone has a choice in every endevour; that in no way negates the fact that naturally occurring psychs such as the one discussed above (psilocybin) posses much more medicinal effects and are far safer for the long run on ones mental health. I've met wayy to many fried out from lsd, mdma, man-made chemicals while those who've used naturals such as mushrooms and cannabis for identical duration and frequency had nowhere near the fried out over fired neurotransmitters on a significant level.

They all are tools that have their proper place.


--------------------
Never Pass Up A Good Thing

"I'd like thank god almighty, for giving everybody else so much...and me so little."
  Dave Chappelle

"There ain't no revolution, only evolution, but every time I'm in Georgia I eat a peach for peace."
Gregg Allman


Edited by O_Dweeds (04/01/19 11:11 PM)


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Re: Dying patients to be given Psilocybes [Re: O_Dweeds]
    #25910897 - 04/02/19 03:46 AM (2 months, 16 days ago)

4-po-dmt is psilocybin...bodhisatta has not been cryptic at all and straightforward explaining it. Not trying to be a dick, but offering constructive criticism here that you need to not read too much into a statement and just take it at face value. Many have that problem

Edit: If you can't sleep after a dose LSD you got some dirty LSD. Everyone reacts differently and it depends on the body chemistry. I think the direct dopamine activity would make a big difference in more reliable results and possibly longer lasting.

Edit 2 : Did those friends use responsibly or did they fry themselves over using as that can happen with anything


Edited by tacodude (04/02/19 03:57 AM)


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OfflineFractal420
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Re: Dying patients to be given Psilocybes [Re: bodhisatta]
    #25910904 - 04/02/19 03:55 AM (2 months, 16 days ago)

Quote:

bodhisatta said:
No
4-po-ho-dmt




Thats real? Psilocybincin?

I usually cant sleep well if i drop lsd after 5pm. Cause im tripping till 5am, at least 3am.
Its not a quality thing for me. If i drop early im all worn out and i sleep like a baby


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It's bright and blue and shimmering.
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Re: Dying patients to be given Psilocybes [Re: Fractal420]
    #25910908 - 04/02/19 03:59 AM (2 months, 16 days ago)

Where you get pailocybincin from?


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OfflineFractal420
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Re: Dying patients to be given Psilocybes [Re: tacodude]
    #25910909 - 04/02/19 04:01 AM (2 months, 16 days ago)

I made up the name but.

4-po-dmt is psilocybin. 4-ho-dmt is psilocin. 4-aco-dmt is Psilatacetin


--------------------
Dreaming of That face again.
It's bright and blue and shimmering.
Grinning wide
And comforting me with it's three warm and wild eyes.

Prying open MY third eye



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Re: Dying patients to be given Psilocybes [Re: Fractal420]
    #25910919 - 04/02/19 04:10 AM (2 months, 16 days ago)

Ok just making sure you know


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Re: Dying patients to be given Psilocybes [Re: Fractal420] * 1
    #25910949 - 04/02/19 05:03 AM (2 months, 16 days ago)

Quote:

Fractal420 said:
I made up the name but.

4-po-dmt is psilocybin. 4-ho-dmt is psilocin. 4-aco-dmt is Psilatacetin



Psilocybin is 4-ho-po-dmt aka 4-po-psilocin

psilocin is 4-ho-dmt


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OfflineGeinstein
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Re: Dying patients to be given Psilocybes [Re: bodhisatta]
    #25910954 - 04/02/19 05:08 AM (2 months, 16 days ago)

:threadmonitor:


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OfflineFractal420
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Re: Dying patients to be given Psilocybes [Re: Geinstein]
    #25910991 - 04/02/19 05:57 AM (2 months, 16 days ago)

You sir are correct, O-phosphoryl-4-hydroxy-N,N-dimethyltryptamine so yes, i actually didnt know it had both a phosphor and hydroxy group

For the person above, 4-aco-dmt is different, it is a synthetic analog but some say its a pro-drug to psilocin (it is O-Acetylpsilocin) while others think its active on its own and has effects very similar to just pure psilocybin crossed with a sort of oral dmt experience. Not the way people usually think of dmt, but def has some similiarities if you ask me.

But its a mushroom analog

So, as far as the article. Too bad this is several months after my friend passed away. I did end up visiting him and left some 4-ho-met. That was the last time i saw or heard from him.

It would be great if those few months ago he could just have regular psilo without me having to sneak a tryptamine to a cancer ward. At least he was able to dab in the bathroom (using one of those battery powered rigs like dr dabber or whatever)

With stomach cancer, if he didnt dab he would just projectile vomit. Even like 25% thc indica bud mixed with cbd was not fast enough to stop the vomiting

I dont know the details, but his gf said the tryptamine helped and he took it. Was like 20mg


--------------------
Dreaming of That face again.
It's bright and blue and shimmering.
Grinning wide
And comforting me with it's three warm and wild eyes.

Prying open MY third eye



Edited by Fractal420 (04/02/19 06:10 AM)


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Invisibletyrannicalrex
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Re: Dying patients to be given Psilocybes [Re: bodhisatta]
    #25911081 - 04/02/19 07:47 AM (2 months, 16 days ago)

Quote:

bodhisatta said:
No
4-po-ho-dmt



I actually thought this was a joke on poor whores,lol.

The more you know.....:grin:


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Re: Dying patients to be given Psilocybes [Re: tyrannicalrex]
    #25912511 - 04/02/19 11:18 PM (2 months, 15 days ago)

That's a new one for me too... That being said I'm beyond familiar with 4-aco-dmt. Even done 4-aco-dpt


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Re: Dying patients to be given Psilocybes [Re: tacodude]
    #25912981 - 04/03/19 07:13 AM (2 months, 15 days ago)

Out of DPT and analogs ive only touched NN-DPT. but ive tried pretty much every 4sub besides 4ho/aco-dpt and things like -eipt

I think 4hoMipt is king personally. Dipt too (ho not aco)

And 4acoDMT has an awesome beautiful depth to it. 4acoDET is similarly interesting but nowhere near as deep (just like -Met)

The only aco i truly* like is DMT, they come on so weird IMO. "Gentle?" Not neccesarily lol. I like the hydroxys, more like real psilo. Curious about 5-Aco-DMT


--------------------
Dreaming of That face again.
It's bright and blue and shimmering.
Grinning wide
And comforting me with it's three warm and wild eyes.

Prying open MY third eye



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Re: Dying patients to be given Psilocybes [Re: Fractal420]
    #25913082 - 04/03/19 08:12 AM (2 months, 15 days ago)

I have some 4-ho-mipt that I barely got before the king of RC's closed,lol. I might have 250mg or 500, IDK. I need to get that out soon....


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Re: Dying patients to be given Psilocybes [Re: tyrannicalrex]
    #25913345 - 04/03/19 10:25 AM (2 months, 15 days ago)

5-aco-dmt would just become 5-ho-dmt or act similarly, which is LD50 200-300 mg/kg...  Not a safe or even psychedelic compound. Only 5-meo-dmt, which I've heard is very different.

4-aco-dpt probably requires high doses so buy weight. Same with 4-ho-dpt


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Re: Dying patients to be given Psilocybes [Re: tacodude]
    #25918827 - 04/06/19 04:13 AM (2 months, 12 days ago)

^thats why ive never been interested in 4xxx-dpt

Mipt is powerful and trippy,  just with 10-20mg

The 4subs are still around, thankfully

Though i myself just use mushroom tea instead lately. I pretty much switched over


--------------------
Dreaming of That face again.
It's bright and blue and shimmering.
Grinning wide
And comforting me with it's three warm and wild eyes.

Prying open MY third eye



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Re: Dying patients to be given Psilocybes [Re: Fractal420]
    #25919234 - 04/06/19 10:45 AM (2 months, 12 days ago)

It's a really worthwhile compound to try if one can get it active


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