krypto2000 said:

That study seems highly suspect. They can't write in english and start off by calling mushrooms an addictive substance. Their test consists of giving a well below threshold dose to rats, 10-30 times less than the average recreational dose, and then claiming it is cardiotoxic. If it were so cardiotoxic at a dose equivalent to about 100mg of mushrooms fruit bodies then everyone here would all be long dead.

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krypto2000 said:

This argument's kind of dumb, 'safe' is subjective, the question should be safe/dangerous in what way? Most drugs are pretty safe when compared to the slew of activities people do every day, few drugs are actually toxic in any way at all, few even have the potential to kill you at even very high doses, opiates and alcohol are the only exceptions that come to mind. Dissociatives, benzos, alcohol, and amphetamines, including mdma, are the only ones I can think of that are neurotoxic and the average user of any of those is far from mentally handicapped, you really have to abuse any of them to cause much damage. You're probably killing more brain cells by pumping gas.

If it weren't for death from respiratory suppression heroin would be extremely safe for all the hate it's getting here, and most people that do die it isn't directly bc of the heroin, but because the purity is not controlled since it's stepped on so much so they overshoot their dose when a stronger batch comes around, not to mention all that fentanyl going around.

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