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Offlinetopdog82
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Why does Alprazolam have such a short effect?
    #24021209 - 01/18/17 07:56 PM (7 years, 1 month ago)

So I took about 2mg a few nights ago because I pulled an all nighter. I was full of caffeine and just needed to get knocked out. I was out of melatonin and valerian. I do benzos a few times a year

Supposedly, the half-life for xanax is about 11.2 hours. 2mg is a lot, esp for me. I was barred out as fuck. I watched an ep on netflix and forgot a significant chunk of it.. If I slept at 12:30am and woke at 9am for class, why was I not barred out for class? I woke up completely fresh and full of energy/normal. not even the grogginess that I get from valerian or high dose melatonin

In general, when I stay up after taking xanax, I feel it has a sort of 2-4 hour effect. Keep in mind I always take xanax alone. I never mix depressants. How the fuck is the half life 11.2 hours? That makes 0 sense?

Am I a fast metabolizer?


from webmd:
The level of drug reaches a peak in the bloodstream after one to two hours, and its felt effects last on average about 5 hours. However, Xanax remains in the bloodstream long after its anti-anxiety effects have worn off. Xanax's average half-life is 11 hours.

So it can't just be me. What causes this? Please let me know. thanks

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Offlinekoods
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Re: Why does Alprazolam have such a short effect? [Re: topdog82]
    #24021396 - 01/18/17 09:00 PM (7 years, 1 month ago)

It's probably shorter than that. But, if you take a single dose, the amount in your blood peaks in a half hour or so, by the timely wake up half the dose or more is gone. if you are not a regular user, you also will develop some tolerance during this time so that the 2mg concentration at mid night feels more than twice as potent as the 1mg at 8am.


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OfflineCrave
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Re: Why does Alprazolam have such a short effect? [Re: topdog82]
    #24021729 - 01/18/17 11:55 PM (7 years, 1 month ago)

Whenever I take xannax I'll be dopey the next morning. I think it lasts ages myself. But then again I got a pretty low tolerance and a .5mg is enough to put me to sleep. I only take it to comedown or sleep as well though.


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InvisibleMidnight_Toker
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Re: Why does Alprazolam have such a short effect? [Re: topdog82]
    #24021936 - 01/19/17 04:21 AM (7 years, 1 month ago)

Half-life is not necessarily indicative of how long a drugs physiological effects are felt, only of how long (on average) it takes for half to be fully metabolized by your body.  It's the plasma concentration, not necessarily the amount  still tickling your receptors.

Your body also works pretty hard to maintain homeostasis, so it could also be that elevated levels of GABA are still present in your synapses, but your brain has temporarily down-regulated your GABA receptors due to that increased amount.  This leaves less places for it to be taken up and used (hence the rebound effects when one stops using benzos or alcohol).

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OfflineSeriously_trippin
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Re: Why does Alprazolam have such a short effect? [Re: Midnight_Toker]
    #24021958 - 01/19/17 04:43 AM (7 years, 1 month ago)

Not at all I know the real half life of diluadid but my doses get me a peak high for about 20-30mins now.


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OfflineAmericanPsycho
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Re: Why does Alprazolam have such a short effect? [Re: Crave]
    #24022237 - 01/19/17 08:27 AM (7 years, 1 month ago)

Quote:

Crave said:
Whenever I take xannax I'll be dopey the next morning. I think it lasts ages myself. But then again I got a pretty low tolerance and a .5mg is enough to put me to sleep




Same for me, but my tolerance is also low because I don't use it that often.  I'll sometimes take 1mg and I'll feel it for most of the day and into the next morning.


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OfflineMorel Guy
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Re: Why does Alprazolam have such a short effect? [Re: AmericanPsycho]
    #24022309 - 01/19/17 08:52 AM (7 years, 1 month ago)

Benzo's hardly slow me down and I don't feel a buzz at all.  Quaaludes on the other hand are awesome.  Valium, ativan, kolonopin all are weak tranquilizers.  Sometimes I only feel the after effects of detox.  Which is odd cause it's a complete surprise due to not feeling any intoxication.


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InvisibleModestMouse
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Re: Why does Alprazolam have such a short effect? [Re: Morel Guy]
    #24022323 - 01/19/17 08:58 AM (7 years, 1 month ago)

Benzo detox can sometimes be really nice, especially if the binge or habit wasn't very long.
The rush of emotions after feeling nothing for so long... ahhh.


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InvisibleMalcolm_Xtasy
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Re: Why does Alprazolam have such a short effect? [Re: ModestMouse] * 4
    #24022344 - 01/19/17 09:06 AM (7 years, 1 month ago)

No thanks.


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OfflineMorel Guy
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Re: Why does Alprazolam have such a short effect? [Re: Malcolm_Xtasy]
    #24022432 - 01/19/17 09:35 AM (7 years, 1 month ago)

I had a script of kolonipin leaving norcal.  The detox messed me up for a bit.  Too much emotion.  Don't remember ever having a buzz but it helped the flight home.

People drink on them.  That seems to make people all goofy and not really know they are at risk.

I like drugs that I know are acting.


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"in sterquiliniis invenitur in stercore invenitur"

In filth it will be found in dung it will be found

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InvisibleMalcolm_Xtasy
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Re: Why does Alprazolam have such a short effect? [Re: Morel Guy]
    #24022459 - 01/19/17 09:42 AM (7 years, 1 month ago)

i really like k-pins. Pretty mellow with a long half life. Xanax just kicks me in the face and makes me want to keep popping em like candy


--------------------
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Offlinegoldcaphunter
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Re: Why does Alprazolam have such a short effect? [Re: Malcolm_Xtasy]
    #24022522 - 01/19/17 10:04 AM (7 years, 1 month ago)

Xanax is weird for me. If say at 6pm I take 5mg I won't feel it all that night. But the next morning I can't walk in a straight line. At least the last 2mg bars I bought off of someone did that to me.

Klonopin I agree feels nice for a couple days then nothing. Ativan I like because it relaxes my muscles.


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OfflineCrave
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Re: Why does Alprazolam have such a short effect? [Re: goldcaphunter] * 1
    #24023101 - 01/19/17 02:32 PM (7 years, 1 month ago)

If I took 5mg I would be in hibernation for 10 hours. How do you even function on that kind of dose? You're probably too high to realise that you're high


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InvisibleMalcolm_Xtasy
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Re: Why does Alprazolam have such a short effect? [Re: Crave] * 2
    #24023111 - 01/19/17 02:36 PM (7 years, 1 month ago)

I took 4 mg last night and don't remember shit.


--------------------
I'm stupid, Enlil is smart.
I'm ugly, Enlil is beautiful.
I'm a loser, Enlil is a winner.
Someday, I hope to be like Enlil but secretly know I never will.

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Offlinekoods
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Re: Why does Alprazolam have such a short effect? [Re: goldcaphunter]
    #24023186 - 01/19/17 03:08 PM (7 years, 1 month ago)

Quote:

goldcaphunter said:
Xanax is weird for me. If say at 6pm I take 5mg I won't feel it all that night. But the next morning I can't walk in a straight line. At least the last 2mg bars I bought off of someone did that to me.

Klonopin I agree feels nice for a couple days then nothing. Ativan I like because it relaxes my muscles.



Wtf? 5mg should knock someone completely out.


--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”

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OfflineDTCharlieB
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Re: Why does Alprazolam have such a short effect? [Re: koods]
    #24023401 - 01/19/17 04:32 PM (7 years, 1 month ago)

I like the long half life of k pins but I can only take very small amounts or it will knock me completely out.  One time I fell asleep sitting outside a bar while on 2 mg.  I didn't even make it inside the bar sat down waiting for my friends then got woke up 6 hours later confused as hell. It sucked because I wanted to bang like 10 bitches that night.  In a row.


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InvisibleBoomer The Great
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Re: Why does Alprazolam have such a short effect? [Re: DTCharlieB]
    #24023405 - 01/19/17 04:34 PM (7 years, 1 month ago)

Your friends didn't notice you outside the bar? Or not care where you were if you were meeting them? LOL they just left you there for 6hrs.

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Onlinepslyke
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Re: Why does Alprazolam have such a short effect? [Re: Boomer The Great] * 2
    #24023467 - 01/19/17 05:09 PM (7 years, 1 month ago)

His friends were there taking care of the 10 bitches he was going to bang that night....


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"What appears impenetrable to us does exist, manifesting itself in the deepest wisdom and the most radiant beauty" Einstein

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Offlinetopdog82
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Re: Why does Alprazolam have such a short effect? [Re: koods]
    #24024041 - 01/19/17 08:16 PM (7 years, 1 month ago)

Quote:

Malcolm_Xtasy said:
I took 4 mg last night and don't remember shit.



surprised. I figure you would have higher tolerance than that

But anyways, I took 2mg again last night due to my inability to sleep. I was fluish and feeling all shitty. I took it at 9pm and remember 0 past 9:30-9:45ish. barred out af again

I felt barred out this morning and throughout the day I was really tired and generally demotivated. I think I didn't get that fogginess because I that previous day I wasn't up to anything particularly exicting
Quote:

koods said:
It's probably shorter than that. But, if you take a single dose, the amount in your blood peaks in a half hour or so, by the timely wake up half the dose or more is gone. if you are not a regular user, you also will develop some tolerance during this time so that the 2mg concentration at mid night feels more than twice as potent as the 1mg at 8am.



damn thats pretty crazy. I didn't know it was that significant of a difference in tolerance. This makes a lot of sense

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