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InvisibleGaspard
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Could the antidepressant mirtazapine decrease dopaminergic drug reward?
    #23968403 - 12/30/16 03:15 PM (7 years, 1 month ago)

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Edited by Gaspard (12/30/16 03:36 PM)


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Offlinexzylocybin
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Re: Could the antidepressant mirtazapine decrease dopaminergic drug reward? [Re: Gaspard]
    #23968556 - 12/30/16 04:10 PM (7 years, 1 month ago)

It sure did for me, I took it for over a year and during that time and about 6 months after I stopped taking it I couldn't enjoy mdma/mushies/L/or opiates nearly as well. I did notice however that Mirtazapine had synergistic effects with cannabis, for me it would increase the minor hallucinations I get from cannabis to almost shroom like proportions, and I would experience deeper and more creative thoughts while mixing the substances than I ever did while on either one alone.


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InvisibleGaspard
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Re: Could the antidepressant mirtazapine decrease dopaminergic drug reward? [Re: xzylocybin]
    #23968604 - 12/30/16 04:35 PM (7 years, 1 month ago)

Quote:

xzylocybin said:
It sure did for me, I took it for over a year and during that time and about 6 months after I stopped taking it I couldn't enjoy mdma/mushies/L/or opiates nearly as well. I did notice however that Mirtazapine had synergistic effects with cannabis, for me it would increase the minor hallucinations I get from cannabis to almost shroom like proportions, and I would experience deeper and more creative thoughts while mixing the substances than I ever did while on either one alone.




That's what I suspected, I also can not feel pleasure with a lot of things that used to give me pleasure.

And I only take it casually as sleep aid. I'm never taking it again. It hits too many brain receptors.

It also took all my motivation, since motivation is linked to dopamine, I guess it decreases dopamine release too.


Edited by Gaspard (12/30/16 05:52 PM)


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