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Invisibletdubz
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Registered: 02/26/12
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How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs
    #23955003 - 12/24/16 07:59 PM (7 years, 2 months ago)

https://www.theguardian.com/technology/2015/jul/11/hack-yourself-nootropic-drugs-upgrade-mind

Jesper Noehr, 30, reels off the ingredients in the chemical cocktail he’s been taking every day before work for the past six months. It’s a mixture of exotic dietary supplements and research chemicals that he says gives him an edge in his job without ill effects: better memory, more clarity and focus and enhanced problem-solving abilities. “I can keep a lot of things on my mind at once,” says Noehr, who is chief technology officer for a San Francisco startup.

The chemicals he takes, dubbed nootropics from the Greek “noos” for “mind”, are intended to safely improve cognitive functioning. They must not be harmful, have significant side-effects or be addictive. That means well-known “smart drugs” such as the prescription-only stimulants Adderall and Ritalin, popular with swotting university students, are out. What’s left under the nootropic umbrella is a dizzying array of over-the-counter supplements, prescription drugs and unclassified research chemicals, some of which are being trialled in older people with fading cognition.

Students used to take drugs to get high. Now they take them to get higher grades
Read more
There is no official data on their usage, but nootropics as well as other smart drugs appear popular in the Silicon Valley. “I would say that most tech companies will have at least one person on something,” says Noehr. It is a hotbed of interest because it is a mentally competitive environment, says Jesse Lawler, a LA based software developer and nootropics enthusiast who produces the podcast Smart Drug Smarts. “They really see this as translating into dollars.” But Silicon Valley types also do care about safely enhancing their most prized asset – their brains – which can give nootropics an added appeal, he says.

One drug class heavily associated with nootropics are racetams, of which there are about 20. The original nootropic, Piracetam, was first synthesised in 1964 by a chemist in Belgium who was struck by its apparent ability to boost mental functioning in even healthy individuals and its safety.

A key ingredient of Noehr’s chemical “stack” is a stronger racetam called Phenylpiracetam. He adds a handful of other compounds considered to be mild cognitive enhancers. One supplement, L-theanine, a natural constituent in green tea, is claimed to neutralise the jittery side-effects of caffeine. Another supplement, choline, is said to be important for experiencing the full effects of racetams. Each nootropic is distinct and there can be a lot of variation in effect from person to person, says Lawler. Users semi-annonymously compare stacks and get advice from forums on sites such as Reddit. Noehr, who buys his powder in bulk and makes his own capsules, has been tweaking chemicals and quantities for about five years accumulating more than two dozens of jars of substances along the way. He says he meticulously researches anything he tries, buys only from trusted suppliers and even blind-tests the effects (he gets his fiancée to hand him either a real or inactive capsule).

Not that everyone likes to talk about using the drugs. People don’t necessarily want to reveal how they get their edge and there is stigma around people trying to become smarter than their biology dictates, says Lawler. Another factor is undoubtedly the risks associated with ingesting substances bought on the internet and the confusing legal statuses of some. Phenylpiracetam, for example, is a prescription drug in Russia. It isn’t illegal to buy in the US, but the man-made chemical exists in a no man’s land where it is neither approved nor outlawed for human consumption, notes Lawler.

Nootroo and Nootrobox are two San Francisco nootropics startups that launched last year. Their founders come from the tech scene and their products are squarely aimed at the tech crowd seeking the convenience of not having to build their own combinations. Each claims big-name Silicon Valley entrepreneurs and investors among their users, though neither will name them.

I am trying to make a smarter, better populace to solve all the problems we have created
Nootroo founder Eric Matzner.
Nootrobox co-founder Geoffrey Woo declines a caffeinated drink in favour of a capsule of his newest product when I meet him in a San Francisco coffee shop. The entire industry has a “wild west” aura about it, he tells me, and Nootrobox wants to fix it by pushing for “smarter regulation” so safe and effective drugs that are currently unclassified can be brought into the fold. Predictably, both companies stress the higher goal of pushing forward human cognition. “I am trying to make a smarter, better populace to solve all the problems we have created,” says Nootroo founder Eric Matzner.

Barbara Sahakian, a neuroscientist at Cambridge University, doesn’t dismiss the possibility of nootropics to enhance cognitive function in healthy people. She would like to see society think about what might be considered acceptable use and where it draws the line – for example, young people whose brains are still developing. But she also points out a big problem: long-term safety studies in healthy people have never been done. Most efficacy studies have only been short-term. “Proving safety and efficacy is needed,” she says.

Both nootropics startups provide me with samples to try. In the case of Nootrobox, it is capsules called Sprint designed for a short boost of cognitive enhancement. They contain caffeine – the equivalent of about a cup of coffee, and L-theanine – about 10 times what is in a cup of green tea, in a ratio that is supposed to have a synergistic effect (all the ingredients Nootrobox uses are either regulated as supplements or have a “generally regarded as safe” designation by US authorities)

The Nootroo arrives in a shiny gold envelope with the words “proprietary blend” and “intended for use only in neuroscience research” written on the tin. It has been designed, says Matzner, for “hours of enhanced learning and memory”. The capsules contain either Phenylpiracetam or Noopept (a peptide with similar effects and similarly uncategorised) and are distinguished by real flakes of either edible silver or gold. They are to be alternated between daily, allowing about two weeks for the full effect to be felt. Also in the capsules are L-Theanine, a form of choline, and a types of caffeine which it is claimed has longer lasting effects.

I can’t try either of the products myself – I am pregnant and my doctor doesn’t recommend it – but my husband agrees to. He describes the effect of the Nootrobox product as like having a cup of coffee but not feeling as jittery. “I had a very productive day, but I don’t know if that was why,” he says. His Nootroo experience ends after one capsule. He gets a headache, which he is convinced is related, and refuses to take more. “It is just not a beginner friendly cocktail,” offers Noehr.

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Offlinemusiclover420
psychonaut
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Re: How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs [Re: tdubz]
    #23956558 - 12/25/16 02:17 PM (7 years, 2 months ago)

Can't wait to see more research into many of these new RC nootropics. Some sound very promising but personally I am wary of possible side effects.

The brain is so complex I imagine most have at least some downside even if it isn't immediately apparent or possibly restricted to certain people :shrug:


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Don't worry about me, I've got all that I need. And I'm singing my song to the sky

You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by

I've got all and more, My smile, just as before. Is all that I carry with me

I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free


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Invisibleellomello
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Registered: 08/11/08
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Re: How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs [Re: musiclover420]
    #23957306 - 12/25/16 08:57 PM (7 years, 2 months ago)

walnuts are a classic nootropic, and oatmeal is a good adaptogen :cookiemonster:


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PAY NO ATTENTION TO THE MAN BEHIND THE CURTAIN get back to the garden

some came singing, some come to play, some come for keeping the dark away

Edited by ellomello (12/25/16 08:58 PM)

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InvisibleAmanita86
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Registered: 09/26/12
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Re: How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs [Re: musiclover420]
    #23957315 - 12/25/16 09:04 PM (7 years, 2 months ago)

That's kind of my view on it.  I'd like to know who/where this stuff is being made too and whether or not a 'sketchy' vendor might tamper/mix something with the final product or if they come from reputable companies.  I've never paid much attention to them until now.


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:mushroom2:Orange clock, pencil:bouncysmoke:
"They threw me off the hay truck about noon...":fishing:
:mushroom2:*Mark 15:34:levitate::mushroom2::blueninja:
Gam zeh ya’avor...:sunny:

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Invisiblepablokabute
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Re: How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs [Re: Amanita86]
    #23957869 - 12/26/16 08:53 AM (7 years, 2 months ago)

half a gram of psilocybin mushrooms gives you 'spirit' and sharpness...

half a gram would be more than 'microdosing' and I find it really really 'stimulating'...

synthetic drugs should have some sorta 'recoil' in the long run... if you know what I mean.

Stick to bacopa monniera and ginseng. xD


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Fermented Mushrooms!!
--- https://www.shroomery.org/forums/showflat.php/Number/23378638/fpart/1/vc/1

'The second seal: “All CONTAMINATED things and events are unsatisfactory.”'



"I envy you. You North Americans are very lucky. You are fighting the most important fight of all - you live in THE HEART OF THE BEAST."

--Anonymous Guerilla, or is he..

Edited by pablokabute (12/26/16 10:08 PM)

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OfflineBlabble40
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Registered: 11/11/14
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Last seen: 1 year, 1 month
Re: How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs [Re: pablokabute]
    #23958141 - 12/26/16 11:37 AM (7 years, 2 months ago)



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Invisibledurian_2008
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Registered: 04/02/08
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Re: How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs [Re: Blabble40]
    #23960215 - 12/27/16 10:51 AM (7 years, 2 months ago)

I read several books on genius, which are to the effect of going into trances and channeling your muse. So, in short, science comes from potions and witchcraft.

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Invisibledurian_2008
Cornucopian Eating an Elephant
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Registered: 04/02/08
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Re: How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs [Re: durian_2008]
    #23960271 - 12/27/16 11:17 AM (7 years, 2 months ago)

Quote:

Users semi-annonymously compare stacks and get advice from forums on sites such as Reddit.

:feelsgoodman:





And, I've just received a psychic message, about how to get ahead, in Silicon Valley --

Go to the fountainhead of all specious virtue signalling and arrested development, for market research. 

:wizard:

Pander to the emotional insecurities of the bourgeois, American Psycho.

Make him feel like god -- for a price.

Edited by durian_2008 (12/27/16 11:25 AM)

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OfflinePezam
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Registered: 01/01/17
Posts: 97
Last seen: 6 years, 10 months
Re: How To Get Ahead in Silicon Valley: Take Nootropic Brain Drugs [Re: durian_2008]
    #23974094 - 01/01/17 08:07 PM (7 years, 1 month ago)

^^haha


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