|
Some of these posts are very old and might contain outdated information. You may wish to search for newer posts instead.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Been "microdosing" daily for over a month AMA 1
#23899828 - 12/06/16 12:40 PM (7 years, 1 month ago) |
|
|
I've been "microdosing" on a 3rd of a gram of cubes (daily) for a little over a month. Since then I have been able to retain more information, have more self confidence, my anxiety is turned way down and I've had the motivation to work out whenever. More people should be doing this! So ya ask me anything that's on topic.
Edited by ichugwindex (12/06/16 12:43 PM)
|
sunshine
Sin18DwireWuTang


Registered: 04/03/04
Posts: 43,592
Loc: higher plane of sex
Last seen: 5 years, 22 hours
|
Re: Been "microdosing" daily for over a month AMA [Re: ichugwindex]
#23899840 - 12/06/16 12:44 PM (7 years, 1 month ago) |
|
|
I used legal herbs a lot which is like microdosing, for the most part, expect for a few of the herbs that really work wonders.
-------------------- One Love True Indeed. Have Good Trips. Mike/sunshine's mom.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Re: Been "microdosing" daily for over a month AMA [Re: sunshine]
#23899848 - 12/06/16 12:46 PM (7 years, 1 month ago) |
|
|
Herbs? Yerbamate? Ganja?
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
sunshine
Sin18DwireWuTang


Registered: 04/03/04
Posts: 43,592
Loc: higher plane of sex
Last seen: 5 years, 22 hours
|
Re: Been "microdosing" daily for over a month AMA [Re: ichugwindex]
#23899856 - 12/06/16 12:49 PM (7 years, 1 month ago) |
|
|
HAHA. Ganja is a legal herb now. I tried over 150 herbs to find the good ones. I almost died a few times. I have heard they are mainly outlawed in parts of Europe now.
-------------------- One Love True Indeed. Have Good Trips. Mike/sunshine's mom.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Re: Been "microdosing" daily for over a month AMA [Re: sunshine]
#23899888 - 12/06/16 01:06 PM (7 years, 1 month ago) |
|
|
My question is which herbs
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
Thayendanegea
quiet walker



Registered: 02/20/12
Posts: 7,596
Loc: 7 Lodges Nation
|
Re: Been "microdosing" daily for over a month AMA [Re: ichugwindex]
#23899927 - 12/06/16 01:23 PM (7 years, 1 month ago) |
|
|
Been thinking about doing this ...I have tried microdosing on occasion, just not on a daily basis though....do you dose more than once a day?
-------------------- Look Deep Into Nature,and Then You Will Understand Everything Better. Albert Einstein
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Re: Been "microdosing" daily for over a month AMA [Re: Thayendanegea]
#23899938 - 12/06/16 01:28 PM (7 years, 1 month ago) |
|
|
Just 1 time a day. I take 0.33 of a gram with breakfast. You should try it man! Especially if you have lots of cubes just sitting around.
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
Edited by ichugwindex (12/06/16 01:29 PM)
|
sunshine
Sin18DwireWuTang


Registered: 04/03/04
Posts: 43,592
Loc: higher plane of sex
Last seen: 5 years, 22 hours
|
Re: Been "microdosing" daily for over a month AMA [Re: ichugwindex]
#23899977 - 12/06/16 01:49 PM (7 years, 1 month ago) |
|
|
It's too dangerous. You're better off not trying herbs. If you read a lot about drugs, you will find something. Some of them are very dangerous. Some people died of kidney failure at some type of clinic using herbs and they banned most of them in parts of Europe, I understand!
-------------------- One Love True Indeed. Have Good Trips. Mike/sunshine's mom.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Re: Been "microdosing" daily for over a month AMA [Re: Thayendanegea]
#23899988 - 12/06/16 01:53 PM (7 years, 1 month ago) |
|
|
I feel like the background noise of life is turned down. Like it lifts the cloud of stress/self doubt thats lingering in the back of my mind. Really my only concern is if prolonged consumption of the alkaloids could be bad for my physical health. I have no idea if thats a legit concern to have or not.
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
Thayendanegea
quiet walker



Registered: 02/20/12
Posts: 7,596
Loc: 7 Lodges Nation
|
Re: Been "microdosing" daily for over a month AMA [Re: ichugwindex]
#23900025 - 12/06/16 02:06 PM (7 years, 1 month ago) |
|
|
I have a lot of wild ovoids (pretty potent) and have felt effects from just eating a single mushroom...just haven't strung any days together yet...I think I may give it a try tomorrow morning.
Do you think it affects your sleep habits at all?
-------------------- Look Deep Into Nature,and Then You Will Understand Everything Better. Albert Einstein
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
I'm all for micro-dosing psilocybin but daily seems too much even at such low doses. I have tried it for a few weeks with 0.3g once every 2-3 days so that eventually I could sustain myself without them.
I'm going to see if Prazosin(aplha blocker) helps because it acts in the same way as magic mushrooms by stimulating and inhibiting regions of the sympathetic nervous system.
Quote:
Psilocybin = sympathomimetic, (of a drug) producing physiological effects characteristic of the sympathetic nervous system by promoting the stimulation of sympathetic nerves.
Quote:
Prazosin = Prazosin is a sympatholytic drug used to treat high blood pressure, anxiety, and posttraumatic stress disorder (PTSD).
sympatholytic = (of a drug) antagonistic to or inhibiting the transmission of nerve impulses in the sympathetic nervous system.
Edited by sudly (12/06/16 02:39 PM)
|
flickedbic
Sojourner



Registered: 03/21/11
Posts: 4,673
Loc: Fractalic Fabric
Last seen: 16 hours, 42 minutes
|
Re: Been "microdosing" daily for over a month AMA [Re: ichugwindex]
#23900186 - 12/06/16 02:59 PM (7 years, 1 month ago) |
|
|
Quote:
Really my only concern is if prolonged consumption of the alkaloids could be bad for my physical health.
This is a valid concern. I like to microdose occasionally, 2x a week, but never daily; and never for an extended amount of time, as this may damage the heart valves:
https://www.reddit.com/r/DrugNerds/comments/2mqqww/psilocin_and_5ht2b_agonism_induced_cardiotoxicity/
-------------------- Favorite entheogen experiences in descending order: 1)Combo of oral DMT + smoked Bufotenine 2)Amanita (urine drank twice) 3)Mushrooms > Achuma 16"+cid(still need higher dose Achuma)> Cid (still need high dose) 4)Morning Glory-HBWR (+cumin, cinnamon aldehyde adducts) > Methyl chavicol (need more activators) 5)Salvia (need to try quid)
All readable matter in the above post is ficticious... any similarities to real life are purely coincidental. Blessing.
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
Re: Been "microdosing" daily for over a month AMA [Re: flickedbic]
#23900261 - 12/06/16 03:28 PM (7 years, 1 month ago) |
|
|
If it's microdosing it's probably not a concern.
Quote:
However, these drugs differ enormously in their half life. Psilocin has a half life of around 2.5 hours following oral psilocybin administration, while cabergoline has a half life of ~65 hours (from the prescribing information), so it will be exposed to cardiac fibroblasts for around 25X as long as psilocin. Extrapolating a very long stretch, a weekly mushroom trip is probably not going to cause cardiotoxicity.
Once every 2-3 days is so that you don't solely rely on psilocybin and can develop your own sense of comfort.
-------------------- I am whatever Darwin needs me to be.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Re: Been "microdosing" daily for over a month AMA [Re: flickedbic]
#23900316 - 12/06/16 03:42 PM (7 years, 1 month ago) |
|
|
I really could not summize anything conclusive from that link. Maybe I should stop doing DAILY though idk
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
flickedbic
Sojourner



Registered: 03/21/11
Posts: 4,673
Loc: Fractalic Fabric
Last seen: 16 hours, 42 minutes
|
Re: Been "microdosing" daily for over a month AMA [Re: sudly]
#23900317 - 12/06/16 03:43 PM (7 years, 1 month ago) |
|
|
Quote:
Alright, final data review on known 5-HT2b agonists causing cardiopathies vs psilocybin. I've been trying to find a drug closer to psilocin in terms of its dosage and resulting plasma concentration relative to its EC 50 for the 5-HT2b receptor, and also one that's only a partial agonist. Bromocriptine (...) (shows) a strong relationship between cumulative dose and risk of developing valvular heart disease.
How do these dosages correlate to the pharmalocologically relevant plasma concentrations? A 7.5 mg dose of bromocriptine results in a maximal plasma concentration of 1.3 ug/L, which equates to 2 nM. 25 mg peaks at 2.4 ug/L, or 3.7 nM. Its half life is 4.83 hours, 2-fold longer than psilocin.
Bromocriptine appears to be able to induce cardiac valvulopathies at concentrations far below the EC 50 (around 50x lower). This would suggest that a 5-HT2b agonist of similar efficacy would also be able to induce valvulopathies at similarly low concentrations. Psilocin's EC-50 of 58 nM means that it could be cardiotoxic at chronic concentrations 1nM. Psilocin shows a peak serum concentration of 8.2 ng/ml, or 40 nM after administration of 15.7 mg (/70kg) psilocybin. Assuming linear dose vs plasma concentration, 0.5 mg of psilocybin would reach the equivalent plasma concentration of bromocriptine in the high dosage study, that's equivalent to 100mg dried P. cubensis assuming 0.5% concentration.
People who report microdosing with mushrooms take more than this much.
If he's right you should definitely stop doing it daily IMO, ichugwindex.
-------------------- Favorite entheogen experiences in descending order: 1)Combo of oral DMT + smoked Bufotenine 2)Amanita (urine drank twice) 3)Mushrooms > Achuma 16"+cid(still need higher dose Achuma)> Cid (still need high dose) 4)Morning Glory-HBWR (+cumin, cinnamon aldehyde adducts) > Methyl chavicol (need more activators) 5)Salvia (need to try quid)
All readable matter in the above post is ficticious... any similarities to real life are purely coincidental. Blessing.
Edited by flickedbic (12/06/16 03:48 PM)
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Re: Been "microdosing" daily for over a month AMA [Re: flickedbic]
#23900358 - 12/06/16 04:02 PM (7 years, 1 month ago) |
|
|
If he is right this is sad news indeed. I've been the happiest I've been in my whole life from daily microdosing and I would hate to have to stop. I've never been so motivated/energized/perceptive so this makes me sad to have to end it.
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
Quote:
'Acute psychological and physiological effects of psilocybin in healthy humans: a double-blind, placebo-controlled dose–effect study'
"Despite the possibility of a short-lasting moderate elevation of blood pressure, in healthy humans without pre-existing medical conditions, no cardiovascular complications must be expected from administration of PY(psilocybin)" http://www.maps.org/research-archive/w3pb/2004/2004_Hasler_20465_2.pdf
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Re: Been [Re: sudly]
#23900466 - 12/06/16 04:37 PM (7 years, 1 month ago) |
|
|
Wait so..Im having trouble seeing where you stand on the subject. I'm not trying to be an ass or anything.
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
BANANA.MAN
Turd Ferguson


Registered: 01/11/15
Posts: 7,474
Loc: Ontario Canada
Last seen: 6 months, 3 days
|
Re: Been [Re: sudly]
#23900472 - 12/06/16 04:40 PM (7 years, 1 month ago) |
|
|
Quote:
sudly said: I'm all for micro-dosing psilocybin but daily seems too much even at such low doses. I have tried it for a few weeks with 0.3g once every 2-3 days so that eventually I could sustain myself without them.
I'm going to see if Prazosin(aplha blocker) helps because it acts in the same way as magic mushrooms by stimulating and inhibiting regions of the sympathetic nervous system.
Quote:
Psilocybin = sympathomimetic, (of a drug) producing physiological effects characteristic of the sympathetic nervous system by promoting the stimulation of sympathetic nerves.
Quote:
Prazosin = Prazosin is a sympatholytic drug used to treat high blood pressure, anxiety, and posttraumatic stress disorder (PTSD).
sympatholytic = (of a drug) antagonistic to or inhibiting the transmission of nerve impulses in the sympathetic nervous system.
Psychedelics are serotonin receptor agonists. The drug You are talking about is an antagonist. Agonists activate receptors and antagonists block them.
|
flickedbic
Sojourner



Registered: 03/21/11
Posts: 4,673
Loc: Fractalic Fabric
Last seen: 16 hours, 42 minutes
|
Re: Been [Re: sudly]
#23900481 - 12/06/16 04:42 PM (7 years, 1 month ago) |
|
|
The question is of cumulative, especially daily, dosage. That study you shared had only four doses given, all of which were spaced out at least two weeks apart. It does not address the issue.
-------------------- Favorite entheogen experiences in descending order: 1)Combo of oral DMT + smoked Bufotenine 2)Amanita (urine drank twice) 3)Mushrooms > Achuma 16"+cid(still need higher dose Achuma)> Cid (still need high dose) 4)Morning Glory-HBWR (+cumin, cinnamon aldehyde adducts) > Methyl chavicol (need more activators) 5)Salvia (need to try quid)
All readable matter in the above post is ficticious... any similarities to real life are purely coincidental. Blessing.
Edited by flickedbic (12/06/16 05:13 PM)
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
Agonist activate receptors(stimulation) which eventually leads to numbing(inhibition).
I'm advocating for a microdose of psilocybin once every 3 days. Psilocybin has a low toxicity(LD-50) and is physically safe in those regards.
@flickedbic Do you have anything better than a reddit blog to support the claim of cardiovascular risks associated with the use of psilocybin?
This is not an adequate reference.
Quote:
My concern is that frequent psilocybin use may result in slight valvular fibrosis which has not been detected yet in users.
-------------------- I am whatever Darwin needs me to be.
|
flickedbic
Sojourner



Registered: 03/21/11
Posts: 4,673
Loc: Fractalic Fabric
Last seen: 16 hours, 42 minutes
|
Re: Been [Re: sudly]
#23900585 - 12/06/16 05:14 PM (7 years, 1 month ago) |
|
|
The thread links a study done in mice using "every other day" dosing: Quote:
http://old.imp.lodz.pl/nowy_pttox/abstracts/streszcz07/Borowiak%20ABSTRACT.pdf (...) shows significant ECG abnormalities in rats (...) here's what hamilton morris had to say about this (above) study: "Like most animal tox studies the dosing regimen does not accurately reflect "normal" patterns of human use, it would be very unusual for anyone to ingest psilocin every other day for 12 weeks, though what is impressive about the study you linked is the very low dose of psilocin administered, which would actually be sub-psychedelic if dosed equivalently in humans.
I certainly do think it's possible for long term, frequent, or high dose use of some psychedelics and empathogens to cause heart valve damage. This is probably more of a concern for people who consume large quantities of 6-APB, DOB or similar high affinity full agonists of 5HT2B, but psilocin could also be a concern if it were used very frequently. So...yeah, don't ingest psilocin everyday would be the takeaway I suppose. "
-------------------- Favorite entheogen experiences in descending order: 1)Combo of oral DMT + smoked Bufotenine 2)Amanita (urine drank twice) 3)Mushrooms > Achuma 16"+cid(still need higher dose Achuma)> Cid (still need high dose) 4)Morning Glory-HBWR (+cumin, cinnamon aldehyde adducts) > Methyl chavicol (need more activators) 5)Salvia (need to try quid)
All readable matter in the above post is ficticious... any similarities to real life are purely coincidental. Blessing.
|
BANANA.MAN
Turd Ferguson


Registered: 01/11/15
Posts: 7,474
Loc: Ontario Canada
Last seen: 6 months, 3 days
|
Re: Been [Re: sudly]
#23900662 - 12/06/16 05:34 PM (7 years, 1 month ago) |
|
|
Quote:
sudly said: Agonist activate receptors(stimulation) which eventually leads to numbing(inhibition).
I'm advocating for a microdose of psilocybin once every 3 days. Psilocybin has a low toxicity(LD-50) and is physically safe in those regards.
@flickedbic Do you have anything better than a reddit blog to support the claim of cardiovascular risks associated with the use of psilocybin?
This is not an adequate reference.
Quote:
My concern is that frequent psilocybin use may result in slight valvular fibrosis which has not been detected yet in users.
What do you mean? When an agonist is bound to a receptor it also blocks it the way an antagonist does but it also stinulates the receptor. Once it is removed by the body the receptor is available again. Maybe i dont understand what you mean.
OP have you found that you need to take it eveyday to get the positive effects?
|
Bill_Oreilly
ANIMALS (the RAINBOW SERPENT)


Registered: 11/12/11
Posts: 26,370
Loc: Boston
|
Re: Been [Re: sudly]
#23900665 - 12/06/16 05:35 PM (7 years, 1 month ago) |
|
|
Quote:
sudly said: Agonist activate receptors(stimulation) which eventually leads to numbing(inhibition).
I'm advocating for a microdose of psilocybin once every 3 days. Psilocybin has a low toxicity(LD-50) and is physically safe in those regards.
@flickedbic Do you have anything better than a reddit blog to support the claim of cardiovascular risks associated with the use of psilocybin?
This is not an adequate reference.
Quote:
My concern is that frequent psilocybin use may result in slight valvular fibrosis which has not been detected yet in users.
Doesnt microdosing every 3 days defeat the purpose? doesnt that give the mushrooms time to exit the body thus wasting the drug and not doing anything for the mind in that situation?
-------------------- Something there is mysteriously formed, Existing before Heaven and Earth, Silent, still, standing alone, unchanging, All-pervading, unfailing, I do not know its name; I call it tao. If forced to give it a name, I call it Great (ta). Being great, it flows out; Flowing out means far-reaching; Being far-reaching, it is said to return. It's just a shot away..
|
nooneman


Registered: 04/24/09
Posts: 14,568
Loc: Utah
|
|
Microdosing is pointless and stupid.
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
That's better, although it is a light hearted critique. A faster heart rate and reduced blood flow may result from excessive use of psilocybin.
@BANANA.MAN Stimulation over time leads to a numbing effect. E.g. Working out
As for OP, once every three days is so that you don't rely on psilocybin to be productive or proactive. Imagine it like a spotter at the gym, it's helpful for a boost but you shouldn't rely solely on them to get you through it.
-------------------- I am whatever Darwin needs me to be.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
|
Quote:
BANANA.MAN
OP have you found that you need to take it eveyday to get the positive effects?
I'm not sure since I've been taking it daily and this is my first attempt at it. Im sure I'll find out in the coming days though since it would seem daily dosing is unhealthy
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
BANANA.MAN
Turd Ferguson


Registered: 01/11/15
Posts: 7,474
Loc: Ontario Canada
Last seen: 6 months, 3 days
|
Re: Been [Re: sudly]
#23900799 - 12/06/16 06:13 PM (7 years, 1 month ago) |
|
|
Im assuming you mean receptor down regulation (when receptors disappear) thats not why microdosing has benefits. It comes from the activation of the receptors not the downregulation of them. Everybody i have talked to says that microdosing has no effect on tolerence to full sized doses. Ive even heard people say they coild microdose and trip later that week. My friend also says he gets some positive effects from just one single microdose. Anyway thats not the point of the thread.
Op please update us if you experiment some more. I think ill try a .5 of cubes sometime because a .3 didnt seem to help me and im not willing to microdose more than 2 or 3 times a week because i would rather teip once in a while.
Edited by BANANA.MAN (12/06/16 06:14 PM)
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
|
I will report back. Tomorrow will be first day without dosing in a little over a month so it should be interesting. Haven't decided if I should slow down to every other day or maybe 2 times a week
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
I'm not talking about tolerance I'm talking about psilocybins inhibitory effects on the sympathetic nervous system which is responsible for regulating the fight or flight response.
It's a benefit because it allows us to act more human like without the distracting interference of gut feelings and intuition. Psilocybin allows us to take the time to focus on our experiences.
-------------------- I am whatever Darwin needs me to be.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
|
Quote:
nooneman said: Microdosing is pointless and stupid.
I would like to know why you feel this way. In the one month I have been doing this I feel like it has improved my life considerably
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
Kinshino
Restful Soul



Registered: 03/11/13
Posts: 1,122
Loc: 5th Dimension
Last seen: 8 months, 5 days
|
|
I've been planning on microdosing. Was thinking to do .2 of penis envies every three days. How do you consume them? You said with breakfast, do you blend it in a smoothie or somethin? Would you think it would help people who suffer from depression?
--------------------
|
BANANA.MAN
Turd Ferguson


Registered: 01/11/15
Posts: 7,474
Loc: Ontario Canada
Last seen: 6 months, 3 days
|
|
Quote:
Kinshino said: I've been planning on microdosing. Was thinking to do .2 of penis envies every three days. How do you consume them?
Psilocin microdoses are best taken rectally imo
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
Quote:
The mechanisms of action of the hallucinogens lysergic acid (LSD) and psilocybin (magic mushrooms) are complex, with various effects on serotonergic, dopaminergic, and adrenergic receptors. These drugs have mild adrenergic effects, producing manifestations of sympathetic arousal such as dilated pupils, sinus tachycardia, hypertension, and hyper-reflexia. Cardiovascular complications are rarely serious, although the potential for arrhythmias and myocardial infarction exist. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1121066/
-------------------- I am whatever Darwin needs me to be.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
|
Quote:
Kinshino said: I've been planning on microdosing. Was thinking to do .2 of penis envies every three days. How do you consume them? You said with breakfast, do you blend it in a smoothie or somethin? Would you think it would help people who suffer from depression?
Rectally. Daily. Jk I just break them up a but like you would with some ganja and drink them down. It's really not too unpleasant with such a small amount or sometimes I do make a shake with some whey protein and toss em in the blender. Honestly if it was an option for me I would grind them to a powder and put it in gell capsules
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
I did gel capsules once and they're great for microdosing, they fit 0.2g in each. Otherwise a mouthful of fruit juice or cordial makes tiny pieces of shrooms easy to swallow.
-------------------- I am whatever Darwin needs me to be.
|
Kinshino
Restful Soul



Registered: 03/11/13
Posts: 1,122
Loc: 5th Dimension
Last seen: 8 months, 5 days
|
|
Quote:
ichugwindex said:
Quote:
Kinshino said: I've been planning on microdosing. Was thinking to do .2 of penis envies every three days. How do you consume them? You said with breakfast, do you blend it in a smoothie or somethin? Would you think it would help people who suffer from depression?
Rectally. Daily. Jk I just break them up a but like you would with some ganja and drink them down. It's really not too unpleasant with such a small amount or sometimes I do make a shake with some whey protein and toss em in the blender. Honestly if it was an option for me I would grind them to a powder and put it in gell capsules
Okay, thanks!
--------------------
|
ZacksJourney
STRANGLER



Registered: 05/02/16
Posts: 543
|
|
I always feel like microdosing has so much to offer and heal, and yet we barely speak of it.
--------------------
ALL MUSHROOMS ARE EDIBLE, some are just only edible once. Trade List
|
Get Shwifty
I love you guys



Registered: 10/14/15
Posts: 167
Last seen: 8 months, 18 days
|
|
I am also microdosing this week. Feels good man.
|
PlantManBee
undifferentiated



Registered: 11/17/16
Posts: 360
Last seen: 1 year, 6 months
|
|
Have you tried microdosing less often and it didn't work? Because I'd think the best thing to do, in any case, would be to aim for the smallest does that still had the positive effect.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
|
Quote:
ichugwindex said: I will report back. Tomorrow will be first day without dosing in a little over a month so it should be interesting. Haven't decided if I should slow down to every other day or maybe 2 times a week
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
|
Feeling pretty much the same today (great!) but its only been 1 day. I have a feeling I will need more tomorrow or the day after. Still open to answer any questions
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
I tried Prazosin last night and I didn't have a vividly lucid dream like usual 
Apparently it's good for (C)PTSD patients too.
-------------------- I am whatever Darwin needs me to be.
|
brainysmurf
Stranger
Registered: 12/05/16
Posts: 8
Last seen: 3 years, 9 months
|
Re: Been [Re: sudly]
#23919249 - 12/12/16 11:24 AM (7 years, 1 month ago) |
|
|
Would love more reports and data on microdosing if anyone has any good links. I'm hoping to utilize stones to experiment with microdosing. If anyone has more feedback experience they could share, I'd love to hear it.
I had my world rocked 18 years ago (havent tripped since) via shrooms and rue and than had some follow up WTF experiences with cannabis and no drugs a few years after.
I been afraid to revisit the "space" till now. I've felt "sticky" mentally/etc. for a few years now which I use to correct via tripping 1-4 times a year. Use to keep me fluid and moving in the right direction with good progress. Hoping the stones can help with that.
|
Apollop


Registered: 03/13/13
Posts: 752
Loc: Egypt
Last seen: 10 months, 13 days
|
|
microdosing every 4th day is way better and more beneficial. look up dr. fadiman, he's one of the experts on the subject of microdosing and he told me this himself.
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
I did micro dosing(0.3g) for about a month and found that 4 days is too big a gap in between doses, 2-3 days in between is my recommendation from personal experience.
-------------------- I am whatever Darwin needs me to be.
|
BANANA.MAN
Turd Ferguson


Registered: 01/11/15
Posts: 7,474
Loc: Ontario Canada
Last seen: 6 months, 3 days
|
Re: Been [Re: sudly]
#23921155 - 12/12/16 09:55 PM (7 years, 1 month ago) |
|
|
Quote:
sudly said: I did micro dosing(0.3g) for about a month and found that 4 days is too big a gap in between doses, 2-3 days in between is my recommendation from personal experience.
I find that a mushroom afterglow after a trip lasts the day after but LSD lasted two for me the one time i have done it so far. Maybe microdosing LSD allows you to take longer gaps.
|
sudly
Darwin's stagger


Registered: 01/05/15
Posts: 10,812
|
|
LSD is known to leave a strong physical sensation for 1-2 days which may be slightly distracting while psilocybin might leaves a pleasant 'hum' so as to say.
I haven't tried microdosing lsd either
-------------------- I am whatever Darwin needs me to be.
|
ichugwindex
Dex



Registered: 06/04/16
Posts: 4,613
Loc: ¯\_(ツ)_/¯
Last seen: 11 months, 2 days
|
Re: Been [Re: sudly]
#23925958 - 12/14/16 01:12 PM (7 years, 1 month ago) |
|
|
I agree every other day is still working quite fine. Might try every 3rd day or something.
-------------------- Only hope can give rise to the emotion we call despair. But it is nearly impossible for a man to try to live without hope, so I guess that leaves Man no choice but to walk around with despair as his companion.
|
showtime007
Noobie cultivator



Registered: 05/23/19
Posts: 156
Last seen: 1 year, 11 months
|
Re: Been "microdosing" daily for over a month AMA [Re: ichugwindex]
#26123773 - 08/06/19 07:56 AM (4 years, 5 months ago) |
|
|
Agreed. I've been taking 5-7 grams fresh daily and feel great. More self confidence, better sleep, memory has improved, and I just feel generally better.
|
showtime007
Noobie cultivator



Registered: 05/23/19
Posts: 156
Last seen: 1 year, 11 months
|
Re: Been "microdosing" daily for over a month AMA [Re: ichugwindex]
#26124840 - 08/06/19 08:22 PM (4 years, 5 months ago) |
|
|
Same here! I've felt the most normal me in a long time!
|
Nikanoru
Stranger



Registered: 02/02/19
Posts: 262
Last seen: 3 years, 7 months
|
Re: Been "microdosing" daily for over a month AMA [Re: showtime007]
#26129075 - 08/09/19 08:33 PM (4 years, 5 months ago) |
|
|
Just started micro-dosing myself. I plan on doing .2 every three days. Kind of went overboard...bought a pack of 1000 gell caps and made them all last night! My wife and best friend are joining in on the micro-dosing as well. Main goal is to reduce anxiety so that I can ween myself off of benzos.
Took my first dose yesterday, was very happy all day although had a bit of anxiety at first that quickly faded. Nothing noticeably different today, well see how tomorrow goes.
--------------------
|
showtime007
Noobie cultivator



Registered: 05/23/19
Posts: 156
Last seen: 1 year, 11 months
|
Re: Been "microdosing" daily for over a month AMA [Re: Nikanoru]
#26131906 - 08/12/19 07:41 AM (4 years, 5 months ago) |
|
|
Today's dose...
|
Shroomei
Even stranger



Registered: 10/02/18
Posts: 188
Loc: Germany
Last seen: 1 year, 29 days
|
Re: Been "microdosing" daily for over a month AMA [Re: showtime007]
#26133877 - 08/13/19 02:14 PM (4 years, 5 months ago) |
|
|
I thought microdosing might be a more interesting (Ok, spectacular) way to get hold of mild depression than SSRIs. So I tested 250-500mg dried GT. These low doses gave me a pleasant buzz. Mild intoxication is great to relax in the evening but nothing I want during the day while working. So I stayed with dosing after work. 500mg twice a week in the evening for about three weeks gave me profound anticipation for these relaxed evenings without a perceptible difference during the day. Overall, this dosing scheme did not work out for me.
|
|