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BANANA.MAN
Turd Ferguson


Registered: 01/11/15
Posts: 7,474
Loc: Ontario Canada
Last seen: 6 months, 3 days
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Re: Are mushrooms safe for my co worker to ingest? [Re: AuroraBorealis88]
#23885167 - 12/01/16 04:53 PM (7 years, 1 month ago) |
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AuroraBorealis88 said: Ya I saw the link and see how it is a little more complex but even then are you sure it's really that black and white? Why do you think all Serotonin receptor agonists would have the same effect on blood pressure?
Theoretically can't there be a serotonin receptor agonist that lowers BP and another one that heightens it? I mean the fact that they're both serotonin receptor agonists is really the only physiological thing that they inherently have in common.
I always thought LSD heightened blood pressure and mushrooms lowered it  I always thought it was just that simple, I mean apparently it's not that simple and like you stated it's a little complex but roughly speaking I still find it to be true enough most of the time.
We have another thread going on right now where people are talking about the up and down nature of mushroom trips and how dynamic they seem, maybe during different stages of the trip it can have different effects on blood pressure?
Im not saying that at all.
they are both serotonin receptor agonists but that is not the only thing they have in common.
not only are they both serotonin receptor agonists they are both 5-HT2 receptor agonists and even more specifically than that they are both 5-HT2a receptor agonists.
But they do effect other serotonin receptors as well so that could alter the effect on BP im not saying it couldnt. im pretty sure LSD affects more receptors than psilocin so they could have a different effect on BP.
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The Blind Ass
Bodhi



Registered: 08/16/16
Posts: 26,658
Loc: The Primordial Mind
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Re: Are mushrooms safe for my co worker to ingest? [Re: BANANA.MAN]
#23885244 - 12/01/16 05:23 PM (7 years, 1 month ago) |
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BANANA.MAN said:
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The Blind Ass said: To put it simply, there is a risk. Beyond that I cannot tell you. This is something he should discuss with his family physician in the privacy of the confidential patient/doctor relationship.
First of all most doctors dont know about the method of action of psychedelic drugs. Only people with an interest in psyches ASWELL as a knowledge of pharmacology know.
And just so you know. A family docor is a jack of all trades and a master of none. Thats why we have specialists. They have to study everything in 7 years. They cant focus on one area. Someone who studies just chemistry and pharmacology for 7 years knows their shit (about those 2 topics) better than a family physician.
Second if he is ignorant and doesnt understand that psyches are different than other drugs in many ways then he may be less likely to prescribe you abusable medication that you may have a legitimate medical need for at some point.
I told my doctor that i smoke weed and drink occasionally because he asked. I wouldnt tell him about any drug that is less socially acceptable than weed or alcohol unless i had a problem.
I honestly think i know more about the chemistry and pharmocology of most family physicians who are not into psyches.
I linked a paper that OP can get his info from.
Thats just my 2 cents.
-------------------- Give me Liberty caps -or- give me Death caps
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Get Shwifty
I love you guys



Registered: 10/14/15
Posts: 167
Last seen: 8 months, 18 days
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Re: Are mushrooms safe for my co worker to ingest? [Re: ergoticmandala]
#23886327 - 12/02/16 12:06 AM (7 years, 1 month ago) |
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Quote:
ergoticmandala said: you should get him to vape some dmt instead. thats a trip condensed into 15 mins
Dr. Rick Strassman said in his book DMT: The spirit Molecule that the only noticeable health concern he had noticed when performing the DMT trials in the 90s is that some patients experienced elevated blood pressure. This is one of the main reasons I'm not going to allow an older family member to try it. The family member in question is also on blood pressure medication.
Edited by Get Shwifty (12/02/16 12:07 AM)
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