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OfflineAuroraBorealis88
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Lysergamides vs Ergolines vs Tryptamines (clarification)
    #23873142 - 11/27/16 07:13 PM (7 years, 2 months ago)

Hey so this question will probably be able to be answered pretty quickly but I figured I'd ask here instead of search myself because I just wanted a clear and relatively concise answer.

So I know LSD is technically an ergoline and a tryptamine alkaloid but my question is, how does this relate to lysergamides?
What is an ergoline alkaloid exactly? I know it's just implying that it's a derivative of ergot but are ergolines and lysergamides the same thing? If not then what's the difference?

And what is the difference between lysergamides and tryptamines? For a while there I thought they were totally different categories of psychedelics just like phenethylamines and tryptamines but I did a little bit of reading somewhere (can't remember where) and it almost seemed like lysergamides were tryptamines in a way...Is this true? Is lysergamide a type or tryptamine? How do these all relate?


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OfflineLogicaL ChaosM
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Re: Lysergamides vs Ergolines vs Tryptamines (clarification) [Re: AuroraBorealis88]
    #23873680 - 11/27/16 10:27 PM (7 years, 2 months ago)

Lysergamides and tryptamines are classes of chemicals based on their base form. For example, Al-Lad is a lysergamide and LSD is one too. There base form is an ergot amide.

Psilocybin is a tryptamine. LSD is not a tryptamine. 4-aco-dmt is also a tryptamine but not a lysergic amide.

Tryptamines are not related to Lysergamines. Different classes. Mescaline is another class, cant remember the name thou. Starts with a P.


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OfflineAuroraBorealis88
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Re: Lysergamides vs Ergolines vs Tryptamines (clarification) [Re: LogicaL Chaos]
    #23873805 - 11/27/16 11:25 PM (7 years, 2 months ago)

Quote:

LogicaL Chaos said:
Lysergamides and tryptamines are classes of chemicals based on their base form. For example, Al-Lad is a lysergamide and LSD is one too. There base form is an ergot amide.

Psilocybin is a tryptamine.
LSD is not a tryptamine. 4-aco-dmt is also a tryptamine but not a lysergic amide.

Tryptamines are not related to Lysergamines. Different classes. Mescaline is another class, cant remember the name thou. Starts with a P.




It's phenethylamine is the class that mescaline, 2C-B and MDMA are in.

Also you say LSD isn't a tryptamine but it is...
LSD is both a tryptamine and a lysergamide whereas mushrooms are just a tryptamine.


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OfflineLogicaL ChaosM
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Re: Lysergamides vs Ergolines vs Tryptamines (clarification) [Re: AuroraBorealis88]
    #23873953 - 11/28/16 12:35 AM (7 years, 2 months ago)

where does it say LSD is a tryptamine?


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OfflineLogicaL ChaosM
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Re: Lysergamides vs Ergolines vs Tryptamines (clarification) [Re: LogicaL Chaos]
    #23873958 - 11/28/16 12:38 AM (7 years, 2 months ago)



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OfflineYeOlde
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Re: Lysergamides vs Ergolines vs Tryptamines (clarification) [Re: LogicaL Chaos]
    #23874660 - 11/28/16 09:37 AM (7 years, 2 months ago)

I think the better way to put it is LSD is a lysergamide but it's structure is shaped like a Tryptamine but it isn't one.


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OfflineEclipse3130
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Re: Lysergamides vs Ergolines vs Tryptamines (clarification) [Re: YeOlde]
    #23874694 - 11/28/16 09:54 AM (7 years, 2 months ago)

it is neither a tryptamine nor a phenethylamine

LSD and its relatives belong to the so called group of the Ergolines.

Technically yes, however it does have the tryptamine back bone, and its actions on 5-ht 2a are from mimicking serotonin but LSD is neither fully a tryptamine or phenethylamine it's a hybrid of the two, an ergoline


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OfflineAuroraBorealis88
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Re: Lysergamides vs Ergolines vs Tryptamines (clarification) [Re: AuroraBorealis88]
    #23874914 - 11/28/16 11:18 AM (7 years, 2 months ago)

But how is it not a tryptamine?

It has the structure for it right there and the guy who made that post on the Nexus incorrectly highlighted the "phenethylamine structure" even though that was a different part of the molecule, the part that essentially makes it a tryptamine.

He brought up the myth that LSD is both a phenethylamine and a tryptamine but that's just a myth, it's an ergoline and a tryptamine or I guess you could also say a lysergamide and a tryptamine right..?

Now I get that ergolines are just lysergamides that are simply derived from ergot so ergolines are essentially certain kinds of lysergamides which are I guess are completely different and not related to tryptamines at all except in LSD's case.

I mean I get full on tryptamine effects from LSD as well, nothing like what I've experienced on 2C-B or 2C-I or even ecstasy. It seems other worldly and alien just like the tryptamines and seems to give extreme perceptual and temporal distortions like tryptamines as well as that shocking hyperreal kind of freakiness. Not to mention the very spiritual almost heavenly themes present.
Now of course it doesn't feel like a pure true tryptamine like mushrooms or something but it does feel similar just qualitatively different and kind of basic in a way.


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