|
Ellis Dee
Archangel



Registered: 06/29/01
Posts: 13,104
Loc: Fire in the sky
Last seen: 4 years, 10 months
|
Magic mushrooms lift severe depression in trial 1
#23868348 - 11/26/16 09:30 AM (7 years, 2 months ago) |
|
|
http://www.telegraph.co.uk/science/2016/05/17/magic-mushrooms-lifts-severe-depression-in-trial/
Magic mushrooms lift severe depression in trial
 Psilocybin, which is found in magic mushrooms, was administered to depression patients in a pill Credit: Alamy
By
Henry Bodkin
17 May 2016 • 1:17pm
A hallucinogenic chemical found in magic mushrooms has successfully lifted severe depression in previously untreatable patients.
Scientists at Imperial College London induced intense psychedelic trips in 12 people using high doses of the banned substance psilocybin.
A week after the experience all the volunteers were depression-free, and three months later five still had no symptoms of the condition.
"I wouldn’t want members of the public thinking they can treat their own depressions by picking magic mushrooms"Dr Robin Carhart-Harris, Imperial College London
Published in the Lancet Psychiatry Journal, the study welcomes the results as “promising, but not completely compelling".
Its authors are now seeking further funding from the Medical Research Council and other bodies to carry out fuller trials.
They conceded, however, that the use of a placebo control, a crucial component of thorough clinical trials, would be difficult as it would be obvious who was having a hallucinogenic experience and who was not.
The psilocybin is believed to cause relief from depression by targeting receptors in the brain and disrupting the Default Mode Network, which is responsible for sense of self and is overactive in depressed people.
However, the scientists did not rule out that the psychedelic trip could have caused an “awakening”, of the kind achieved by spiritual teaching, which also helped lift the depression.
 Professor David Nutt said current regulations made clinical trials extremely difficult Credit: UNIVERSAL NEWS AND SPORT
An estimated 350 million people worldwide are affected by the disease and the annual cost to the economy in England is thought to be around £7.5 billion, according to government figures.
About one in ten patients are resistant to treatment.
Despite the promising results, the researchers urged people not to try magic mushrooms themselves as a cure for depression.
Lead author Dr Robin Carhart-Harris, said: “Psychedelic drugs have potent psychological effects and are only given in our research when appropriate safeguards are in place, such as careful screening and professional therapeutic support.
“I wouldn’t want members of the public thinking they can treat their own depressions by picking their own magic mushrooms.
“That kind of approach could be risky.”
The volunteers in the trial had the psilocybin administered orally in capsules and were then closely monitored.
Professor David Nutt, who also took part in the research, criticised the “Kafkaesque” tangle of regulations and licencing requirements that had forced the team to wait 32 months before being allowed to conduct the trial.
“It cost £1,500 to dose each person, when in a sane world it might cost £30,” he said.
“It is important that academic research groups try to develop possible new treatments for depression as the pharmaceutical industry is pulling out of this field.
“Our study has shown psilocybin is safe and fast-acting, so may, if administered carefully, have value for these patients.”
Professor Nutt, who was sacked as the Government’s drugs advisor in 2009 for his outspoken views, urged the Home Secretary to re-designate psilocybin from Schedule 1 of the Misuse of Drugs Act to better enable further clinical trials.
Amanda Feiling, from the Beckley Foundation, which also took part in the research, said: “For the first time in many years, people who were at the end of the road with currently available treatments reported decreased anxiety, increased optimism and an ability to enjoy things.
“This is an unparalleled success and could revolutionise the treatment of depression.”
-------------------- "If the foundations be destroyed, what can the righteous do."-King Solomon And there was war in heaven: Michael and his angels fought against the dragon; and the dragon fought and his angels,
|
tyrannicalrex
Strange R



Registered: 04/24/03
Posts: 38,323
Loc: subtropics
|
Re: Magic mushrooms lift severe depression in trial [Re: Ellis Dee]
#23868367 - 11/26/16 09:35 AM (7 years, 2 months ago) |
|
|
wicked!
|
leschampignons
Biochemistry + Mycology


Registered: 08/30/13
Posts: 1,583
Loc: NY/NJ/ME
Last seen: 4 days, 8 hours
|
Re: Magic mushrooms lift severe depression in trial [Re: Ellis Dee] 2
#23868409 - 11/26/16 09:55 AM (7 years, 2 months ago) |
|
|
A link to the actual paper here
Sample size is small (n=12) There is no control group. Psilocybin mushrooms are almost certainly medically valuable, but this study is not very robust.
|
nice1returns
I am the Holy Shit



Registered: 09/04/14
Posts: 2,303
Loc: miwuaki
|
Re: Magic mushrooms lift severe depression in trial [Re: leschampignons] 1
#23868526 - 11/26/16 10:39 AM (7 years, 2 months ago) |
|
|
Yer no shit any chemical/drug/plant/extract/food will lift depression from surpression and oppression by your own fucking government, its about time we fight the fuck back?
Or keep getting raped in the ass and mind fucked by the system and paying for their guys in white coats to feed us more pills?
We are sick of being force fed and sold beliefs by a corrupt governemnt of egoism that (no shit) ego maniacs rise to power in the domainate the good people. I can put a suit on a monkey and get him to read anything, it doesn't make it legitimate. We all know its bullshit. Its about time we fucking start the revolution - the empire of SHIT is collapsing and we all know it. Study history.
Nothing can stop us now. Nothing can stop growth or evolution. The old way is dying. Their kind are dying out. Those who seek to manipulate and control others via emotion and ego - its game set n match - look at whats happening. Bye your big ego'ed bastards - we have evolved, we have united, the light shines through the darkness, this is growth, this is evollution, nothing can stop it, no human mind can stop life and progression itself, you are finished.
The UK is the EPITIMAY of people with no self belief - looking to men in lab coats to study them and feed them chemicals for cash. Fuck that. Wake up. Fight back. Use their system against them. We are already in position to checkmate now. Don't ever if you yourself know better than your "gov" ofc you do. Loo0k at what they have done to you.. https://www.theguardian.com/politics/2002/apr/21/uk.medicalscience ; Thats what you pay for. Thats where your tax money goes ffs don't defend it?
Nobody shud ever let a cash hungry governement or family or school tell them what to think and do. These guys are the darkness, the represent the control system of corruption. We don't want it, we don't need it. WE ARE GOOD PEOPLE. We know they are corrupt. Fight back in every possible way - USE THEIR SYSTEM AGAINST THEM.
They use divide and conquer - the good/bad angel devil complex to control you via shame and reward like an animal. Make people believe in good/bad and judge others. We need to educate and use their system against them. That is how you can end the depression.
The UK gov lied to you to control you via fear and harvest your work energy. FIGHT THE FUCK BACK NOW, don't use terror, these are the beings of fear and terror, use their system against them
Edited by nice1returns (11/26/16 11:10 AM)
|
LeeHarvOz
Homie



Registered: 10/13/10
Posts: 2,339
Last seen: 1 year, 7 days
|
Re: Magic mushrooms lift severe depression in trial [Re: nice1returns] 2
#23868591 - 11/26/16 11:03 AM (7 years, 2 months ago) |
|
|
i've been depressed for years if not a decade. recently (last 6 to 8 months) it got really severe. i got to the point were i really hated myself, thought about suicide on a daily basis, woke up depressed an anxious every day, slept as much as i could and just had terrible thoughts running through my head all day every day.
a little more than a week ago i had a little bit of a break down and ate a bunch of xanax, it got so bad i wanted to hurt myself so i shot up heroin for the first time, something i claimed id never do, just to stab myself with something and do drugs in a more self destructive way that i know could kill me, sort of same mentality as playing russian roulette. i called my ex who was a big source of my depression after the shot mumbled incoherently with her for a while. after hanging up the conversation made me realized i needed to change or i was gunna kill myself one day. thats when i ate the first 3.5 grams, throughout the night i ate another 2-3 grams but by morning i couldn't eat any more because they were upsetting my stomach so i lemon tekd another 8th then sort of blacked out for a while till i came too naked in my bed. it was the most profound healing psychedelic experience I've had I'm my life. it truly was like taking a medicine to alleviate an illness like how some shamans consider psychs to be medicine in that capacity.
i learned a lot during this trip. i learned to be grateful for and happy about the relationships i have not depressed that they're not what they used to be. i learned to be a optimist rather than a pessimist which I've been my whole life. and i've learned to be happy, a sensation i haven't known in years if not longer, i forgot what it even felt like. i haven't been depressed, in fact i still feel happiness, no thoughts of suicide or harming myself, not even negative thoughts about my ex or my past with her since, and these thoughts would consume my days thinking a week and a half ago.
|
nice1returns
I am the Holy Shit



Registered: 09/04/14
Posts: 2,303
Loc: miwuaki
|
Re: Magic mushrooms lift severe depression in trial [Re: LeeHarvOz]
#23868604 - 11/26/16 11:06 AM (7 years, 2 months ago) |
|
|
PM me man <3
|
LeeHarvOz
Homie



Registered: 10/13/10
Posts: 2,339
Last seen: 1 year, 7 days
|
Re: Magic mushrooms lift severe depression in trial [Re: nice1returns]
#23868626 - 11/26/16 11:12 AM (7 years, 2 months ago) |
|
|
pm sent
|
Ellis Dee
Archangel



Registered: 06/29/01
Posts: 13,104
Loc: Fire in the sky
Last seen: 4 years, 10 months
|
Re: Magic mushrooms lift severe depression in trial [Re: LeeHarvOz]
#23868711 - 11/26/16 11:37 AM (7 years, 2 months ago) |
|
|
Quote:
LeeHarvOz said: i've been depressed for years if not a decade. recently (last 6 to 8 months) it got really severe. i got to the point were i really hated myself, thought about suicide on a daily basis, woke up depressed an anxious every day, slept as much as i could and just had terrible thoughts running through my head all day every day.
a little more than a week ago i had a little bit of a break down and ate a bunch of xanax, it got so bad i wanted to hurt myself so i shot up heroin for the first time, something i claimed id never do, just to stab myself with something and do drugs in a more self destructive way that i know could kill me, sort of same mentality as playing russian roulette. i called my ex who was a big source of my depression after the shot mumbled incoherently with her for a while. after hanging up the conversation made me realized i needed to change or i was gunna kill myself one day. thats when i ate the first 3.5 grams, throughout the night i ate another 2-3 grams but by morning i couldn't eat any more because they were upsetting my stomach so i lemon tekd another 8th then sort of blacked out for a while till i came too naked in my bed. it was the most profound healing psychedelic experience I've had I'm my life. it truly was like taking a medicine to alleviate an illness like how some shamans consider psychs to be medicine in that capacity.
i learned a lot during this trip. i learned to be grateful for and happy about the relationships i have not depressed that they're not what they used to be. i learned to be a optimist rather than a pessimist which I've been my whole life. and i've learned to be happy, a sensation i haven't known in years if not longer, i forgot what it even felt like. i haven't been depressed, in fact i still feel happiness, no thoughts of suicide or harming myself, not even negative thoughts about my ex or my past with her since, and these thoughts would consume my days thinking a week and a half ago.
That is the most inspirational story I've ever read on the shroomery. Second only to the greatest story, the story of Jesus Christ and redemption! Thank you so much for sharing!!!!!! And God bless you so much!!!!!!    
-------------------- "If the foundations be destroyed, what can the righteous do."-King Solomon And there was war in heaven: Michael and his angels fought against the dragon; and the dragon fought and his angels,
|
LeeHarvOz
Homie



Registered: 10/13/10
Posts: 2,339
Last seen: 1 year, 7 days
|
Re: Magic mushrooms lift severe depression in trial [Re: Ellis Dee] 1
#23868729 - 11/26/16 11:40 AM (7 years, 2 months ago) |
|
|
thanks for the kind words, I'm really glad it effected you like that. there is hope for everyone after all i guess.
|
LeeHarvOz
Homie



Registered: 10/13/10
Posts: 2,339
Last seen: 1 year, 7 days
|
Re: Magic mushrooms lift severe depression in trial [Re: LeeHarvOz]
#23868736 - 11/26/16 11:42 AM (7 years, 2 months ago) |
|
|
lets hope it lasts, research suggests these effects may fade in 2weeks to 3 months.
|
thehighking
Shaman

Registered: 11/04/16
Posts: 63
Last seen: 6 years, 11 months
|
Re: Magic mushrooms lift severe depression in trial [Re: LeeHarvOz]
#23869445 - 11/26/16 03:46 PM (7 years, 2 months ago) |
|
|
Psychedelics are BAD! The widespread use of psychedelics will lead to loss of profts of massive pharmaceutical companies. If you are cured of your illness then how will they make money? What about the taxes? If these medicines can grow for free in nature then how will these companies make money at your expense?
-------------------- "Reality is merely an illusion, albeit a very persistent one" Albert Einstein
|
Eywa_devotee
Goddess Worshiper


Registered: 10/04/10
Posts: 1,088
Loc: State of Confusion, Arkan...
Last seen: 3 years, 7 months
|
Re: Magic mushrooms lift severe depression in trial [Re: thehighking]
#23870380 - 11/26/16 08:19 PM (7 years, 2 months ago) |
|
|
Lifts depression, but if the circumstances you have that are making you depressed don't change, back into the despair you go. Would be best as a tool to crack the head open so therapy can work.
-------------------- "Love one another." "To Love is to know me." "Love is the Law, Love under Will." "In Compassion, all sorrows end." Regardless of the Master, the message is the same- Choose love and you shall live, Choose Fear and you shall die. Help bring peace to this Earth: Love one another, and serve others before yourself.
|
LSDollar


Registered: 02/09/15
Posts: 2,361
Loc: Up Up and Away
|
Re: Magic mushrooms lift severe depression in trial [Re: Eywa_devotee] 1
#23871185 - 11/27/16 06:33 AM (7 years, 2 months ago) |
|
|
It helped me cure my SEVERE depression 2 years ago. It was constant, for years on end. It took me a few trips, but when the shrooms went away, I really felt like a better, happier person. Its been 2 years since I last dosed, and the deperession comes and goes, this last month it has been fairly bad, but thats because I am trying to get off this 1-4MG/day xanax binge I been on for the past month.
|
LeeHarvOz
Homie



Registered: 10/13/10
Posts: 2,339
Last seen: 1 year, 7 days
|
Re: Magic mushrooms lift severe depression in trial [Re: LSDollar]
#23871992 - 11/27/16 12:58 PM (7 years, 2 months ago) |
|
|
Quote:
mirraco said: It helped me cure my SEVERE depression 2 years ago. It was constant, for years on end. It took me a few trips, but when the shrooms went away, I really felt like a better, happier person. Its been 2 years since I last dosed, and the deperession comes and goes, this last month it has been fairly bad, but thats because I am trying to get off this 1-4MG/day xanax binge I been on for the past month.
How often did you take those few trips? did you wait for the depression to be in all swing again or id you take it at the first signs before it had a chance to manifest further? i don't know what my plan is yet if i fall bak into my "normal" depressed state of mind in a few weeks or months. I'm not sure if i should take a bunch when the depression first statrs and try to nip it in the bud, or keep trying to fight it untill it becomes unbearable again then take another massive trip.
|
PumpJackTeX
livin life



Registered: 05/26/08
Posts: 3,951
Loc: California
Last seen: 10 months, 30 days
|
Re: Magic mushrooms lift severe depression in trial [Re: LeeHarvOz]
#23876830 - 11/28/16 11:24 PM (7 years, 2 months ago) |
|
|
It's been over 4 years since I tripped
I took LSD last weekend & it has helped my mentality so much.
My dad passed away a few month's ago and even before That I have been stressed and not been happy much.
After last weekend my entire mindset has changed & I hope it stays that way.
-------------------- Life. 2008 Ascension Energy | UFOs | 2021
|
no0bsawse
Yearnin' for Learnin'


Registered: 08/26/16
Posts: 104
Last seen: 5 years, 1 month
|
Re: Magic mushrooms lift severe depression in trial [Re: thehighking]
#23877329 - 11/29/16 06:03 AM (7 years, 2 months ago) |
|
|
Quote:
thehighking said: Psychedelics are BAD! The widespread use of psychedelics will lead to loss of profts of massive pharmaceutical companies. If you are cured of your illness then how will they make money? What about the taxes? If these medicines can grow for free in nature then how will these companies make money at your expense?
I literally get in a frustrating thought loop every time I think about this
-------------------- LF: Gourmet Strains
|
ShroomerInTheRye
Clit Commander



Registered: 01/12/12
Posts: 13,036
Loc: Themyscira
|
Re: Magic mushrooms lift severe depression in trial [Re: Ellis Dee] 1
#23878409 - 11/29/16 02:10 PM (7 years, 2 months ago) |
|
|
I have been clinically diagnosed with pretty severe, treatment resistant depression. I can verify that mushrooms really do help a lot with depression. I can't say I've been able to keep it off, though, as much as I use mushrooms, but I do feel a little less shitty each time I use them. I took some LSD a few days ago and actually had the energy to do stuff like the dishes and cook a meal.
Psychedelics are totally way better to treatment of mental health issues than any SSRI.
--------------------
<-- Clicky Clicky
|
no0bsawse
Yearnin' for Learnin'


Registered: 08/26/16
Posts: 104
Last seen: 5 years, 1 month
|
Re: Magic mushrooms lift severe depression in trial [Re: ShroomerInTheRye] 1
#23878887 - 11/29/16 04:54 PM (7 years, 2 months ago) |
|
|
Quote:
ShroomerInTheRye said: I have been clinically diagnosed with pretty severe, treatment resistant depression. I can verify that mushrooms really do help a lot with depression. I can't say I've been able to keep it off, though, as much as I use mushrooms, but I do feel a little less shitty each time I use them. I took some LSD a few days ago and actually had the energy to do stuff like the dishes and cook a meal.
Psychedelics are totally way better to treatment of mental health issues than any SSRI.
Hell yeah man, fuck big pharma, doctors hardly understand what they are doing when they are trying to prescribe medication to treat physical symptoms, let alone mental ones.
One year of pharmacology is not enough to educate a person who otherwise has known nothing about psychoactive substances into a "Doctor"
-------------------- LF: Gourmet Strains
|
CLIT
Stranger
Registered: 01/23/12
Posts: 2,758
Last seen: 1 year, 11 days
|
Re: Magic mushrooms lift severe depression in trial [Re: no0bsawse]
#23879254 - 11/29/16 06:32 PM (7 years, 2 months ago) |
|
|
They should study the more legal amanitas effect on depression!
|
LeeHarvOz
Homie



Registered: 10/13/10
Posts: 2,339
Last seen: 1 year, 7 days
|
Re: Magic mushrooms lift severe depression in trial [Re: CLIT]
#23885290 - 12/01/16 05:37 PM (7 years, 1 month ago) |
|
|
still not really depressed, only for two days and not too bad. I've been experiencing anxiety tho and felt i was slipping back. i just attempted a .4g micro dose today but it made me trip a little and was and wasn't a micro dose. well see if that helps at all, i do feel happy now that I've come down.
|
|