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Offlineagreedwitboardrule
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Different strains, different trip? Science?
    #23846786 - 11/18/16 09:23 PM (7 years, 2 months ago)

Yo

I wanted to ask,


Is there any scientific research showing that different strains of shrooms are different chemically?

The internet has people saying:

All strains are the same, they're all shrooms which all produce the same chems.

And some other people saying:

Different strains feel different, i tripped different.


I am more inclined to believe the first one, its all shrooms and all the same chems, the different trip is just peoples experience at that point in time/setting.


Thoughts?

I'd love to know 100% which is correct, if we have any scientists/100% knowing people here.

Thank you.


--------------------
I like you.


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OfflinePinPornProducer
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Re: Different strains, different trip? Science? [Re: agreedwitboardrule]
    #23846816 - 11/18/16 09:32 PM (7 years, 2 months ago)

Cube trip is a cube trip, some grows are heavy on the body and less visual. Some are hardly any body load and very visual. All depends on chemical make up of the fruits. But all in all the trips are basically the same other than mind set and setting obviously


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: PinPornProducer]
    #23847913 - 11/19/16 09:45 AM (7 years, 2 months ago)

There *are* a bunch of various tryptamines within the psilocybe family besides psilocin, psilocybin, and beacystine(sp?), however those are the main 3. Those three all feel indistinguishable from one another from any trip report you'll read of people who have taken the pure compounds. Now consider that beacystine(sp?) occurs at about 1% that of psilocin and psilocybin and you have to conclude that regardless how it feels it's definitely not contributing to the experience with the amounts present. By extension the other tryptamines in there are at even lesser amounts so regardless how active or different they are it's pretty safe to conclude they are not doing anything either.


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OfflineEclipse3130
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23847945 - 11/19/16 09:56 AM (7 years, 2 months ago)

Magic Mushrooms contain 3 main psychoactive compounds: Psilocybin, psilocin and less common and lower amounts of in dried cubensis baeocystin/norbaeocystin.

Psilocybin is the main component of magic mushrooms: Phosphoro-hydroxy-DMT
When Psilocybin passes through the liver and stomache when consumed it is dephosphorized, leaving Hydroxy-DMT otherwise known as Psilocin - this is the active drug which causes the trip.

Psilocybin, psilocin and baeocystin are found in their highest levels of fresh mushrooms. - When dried, almost to all psilocin is lost, due to the degradation in the presence of oxygen.

Baeocystin is usually unmentioned or unheard of, it's an active precursor to psilocybin but is usually found in low amounts and other species of Psilocybes.

Cubensis strains don't differ that vastly, with the exception of Penis Envy, a stable mutant hybrid cross. Set and Setting is what makes trips different, psilocybin and psilocin are always going to have the same mechanism of action in your body, certain strains aren't more visual than others, it's the amount you take, the way you consume it, your mind state and your physical surroundings which make the trip change.

:cheers:


--------------------
"In The Material World One seeks retirement and grows Old
In The Magical World One seeks Enlightenment and grows Wiser
In The Miraculous World One seeks nothing and grows Lighter
As we all tread the Homeward Path we will explore many Realms
And one day... we will all Realize that all experiences are Simply
Different ways in which The
All-That Is
Perceives Itself"


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OfflineAuroraBorealis88
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23848305 - 11/19/16 11:41 AM (7 years, 2 months ago)

Quote:

krypto2000 said:
There *are* a bunch of various tryptamines within the psilocybe family besides psilocin, psilocybin, and beacystine(sp?), however those are the main 3. Those three all feel indistinguishable from one another from any trip report you'll read of people who have taken the pure compounds. Now consider that beacystine(sp?) occurs at about 1% that of psilocin and psilocybin and you have to conclude that regardless how it feels it's definitely not contributing to the experience with the amounts present. By extension the other tryptamines in there are at even lesser amounts so regardless how active or different they are it's pretty safe to conclude they are not doing anything either.




Even if it's just 1% it still has an effect because the effects of the psilocybin make you more susceptible and receptive to the effects of other alkaloids, it's due to a synergy. This is how THC and cannabinoids work too, without THC the other terpenes don't have noticeable psychological effects.


Edited by AuroraBorealis88 (11/19/16 11:43 AM)


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23848322 - 11/19/16 11:50 AM (7 years, 2 months ago)

The other terpenes don't have a noticeable psychological effect. Just because people say they get a different high doesn't make it so. People say they get different types of drunk from different types of alcohol too, but that's also a bunch of BS.


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OfflineAuroraBorealis88
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23848394 - 11/19/16 12:11 PM (7 years, 2 months ago)

Quote:

krypto2000 said:
The other terpenes don't have a noticeable psychological effect. Just because people say they get a different high doesn't make it so.




I honestly have no idea what you're talking about. What I said wasn't up for debate lol that's simply how alkaloids and terpenes work when it comes to these various natural hallucinogens.


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23848404 - 11/19/16 12:14 PM (7 years, 2 months ago)

Can you give me a reference then? Science has shown that some terpenes have psychological effects, eg a high. It has *not* shown that the minute levels within cannabis do this. It *has* shown that cannabis potentiates the high of terpenes, or more so vice versa. It has, again however, *not* shown this to happen with the minute amounts present within cannabis. The same goes for every other cannabinoid besides THC and CBD. It has shown that without CBD the high is measureably more anxious, psychedelic, etc. I don't think measuring these supposed minute differences is even within the realm of science currently, I mean how would you do that short of asking people? They don't appear to act differently, it's entirely subjective. As such it's entirely open for debate at present. Show me a reference otherwise and I'll admit I'm wrong. Do you think that different types of alcohol provide different types of drunkeness short of the potency and perhaps things that contribute to a hangover? Different types of yeast and fermentation mediums *do* provide a different range of alcohols, ketones, etc. Is the trace amounts of acetone in my beer contributing to the high because it is potentiated by the alcohol?


Edited by krypto2000 (11/19/16 12:20 PM)


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OfflineAuroraBorealis88
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23848430 - 11/19/16 12:25 PM (7 years, 2 months ago)

It's called the entourage effect and, this stuff has been known since the 90s.
Pure THC gives different effects than what you would get from the smoked cannabis buds. Even if you had some pure CBD along with the THC it still wouldn't feel like how it would to smoke the actual cannabis plant. 
The other terpenes aren't "unlocked" by the THC necessarily it's just they add to the qualitative effects of the high which is why different strains with different cannabinoid and terpene profiles have slightly different qualitative effects, the dosage of THC matters far more than the strain and so does the method of administration but the strain does make some small differences. In a way THC really just turns your mind into a cannabinoid detector, I'm sure even tea could change the quality of your high due to it also having cannabinoids I believe not just caffeine.

Also different kinds of alcohol do give different kinds of drunk. There's no science out there right now to confirm or debunk this I've already done the research looked into it however there are some theories. It really just comes down to different chemicals.


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23848495 - 11/19/16 12:47 PM (7 years, 2 months ago)

So if there's no science to back it up it hasn't been 'known' since the 90's and it's far from a fact as you previous said, it's been speculated and speculation does not make something true. Until it's proven it's my belief vs yours. My belief, which is based on my personal experience, as I'm sure yours is based on your personal experience, is that there is no difference. I don't think most people can even tell a difference between a sativa and indica based on the high alone, much less trace terpenes and cannabinoids. This happens with every drug. Look at blind taste tests with wines, you can't argue that they do most certainly taste differently, that *is* a fact, yet under a blind test people often can't even tell the difference between a white and a red a lot of the time, much less more specific differences. You should at least be open to the possibility that subjectively there really is no difference.


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Invisibleopenmind
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23848996 - 11/19/16 03:32 PM (7 years, 2 months ago)

Quote:

krypto2000 said:
....My belief, which is based on my personal experience, as I'm sure yours is based on your personal experience, is that there is no difference. I don't think most people can even tell a difference between a sativa and indica based on the high alone, much less trace terpenes and cannabinoids....







I certainly do notice a difference between some strains from personal experience. Lots of strains are middle of the road hybrids these days with similar effects and genetics...and I also feel if a strain isn't grown well, and isn't dried & cured nice and proper (rather important), it's just going to produce a generic high/buzz....but there are strains out there that consistently have the same distinct effects for me over all the years I've been smoking, and/or are at way different ends of the spectrum for me (like how can one smoke green crack and say it's the same exact high as something like Purple Kush...?...two completely different highs for me)


I notice all sorts of variables, from how quickly or slowly a high comes on, how long it lasts, if I'm left feeling burnt out/cloudy minded a while after smoking or if I simply come back down to being "sober" again. Some strains make my mind race and keep me up/stimulated so much so that I can't smoke them before bed (like Green Crack), but they are great to wake up to as it's like a cup of coffee for me...Others silent my mind and relax me, so much so that I don't like to smoke them during the day much. Some strains induce anxiety, others have a powerful distinct anxiolytic effect (sunset sherbet is one strain that has a distinct anxiolytic and mood up lifting aspect for me)....and lots of other subtle differences in the way some strains influences my mind.

Even when I write up a review of a strain before reading about what other folks have to say about it, more often than not other folks that have written reviews of the same strain note the same exact characteristics in the high that I noticed.


I don't feel that smoking/vaping a combo of isolated/pure THC & CBD is going to be exactly the same as smoking/vaping a bowl of super resinous terpy flower. I think there's far more at work than just THC & CBD modulating the high....There's even a difference in the high between dabbing oils/wax/shatter versus smoking flower....And vaporizing weed versus smoking it also produces a different high.


As for alcohol...I've never noticed a difference in the buzz from different types of alcohols, at all....but super hoppy IPA beers do tend to make me rather sleepy and sedated (assuming from all the hops in the beer), a plain ol' shot or two of vodka won't make me feel relaxed/sedated like a hoppy IPA beer or two will.







Anyway...with all that said, I personally haven't noticed any difference between strains or species of active mushrooms besides potency. I've mostly been working with ps cyans and ps allenii over the past few years and don't notice any differences between the two, or differences compared to my trips with cubes years ago....But since I've been working with these two wood-lover species for so long I am interested in taking a comparable dose of cubes just to see if there's any subtle/noticeable differences, any of which I should certainly notice since I haven't ate any cubes in several years....And I've always wanted to have the opportunity to try various strains of cubensis from around the world, just to see if there's any differences that some folks talk about.


The biggest, actually the only, difference in effects that I've noticed with mushrooms, and it's pretty pronounced, is eating them when they're still fresh versus eating them when they've been dried...Don't know if it's just because of the higher levels of psilocin when they're fresh, and/or because of traces of other alkaloids that oxidize/break down easily upon drying, but I find there's quite a difference between fresh and dried mushrooms....It's more than them merely being more potent, the visual component is much more pronounced for me with fresh fruits, the entire experience is richer/cleaner/clearer/fresher feeling, I can't explain it, they just have a certain "zing" and quality to them when fresh that is not present when dried.

First time I nommed down just a single 10g fresh cyan mushroom, I was awe-mazed....and now I look forward to this time of year because it's the only time I get the chance to eat fresh fruits :smirk: .







-OM


.


--------------------


Edited by openmind (11/19/16 03:38 PM)


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OfflineAuroraBorealis88
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23849236 - 11/19/16 04:57 PM (7 years, 2 months ago)

Quote:

krypto2000 said:
So if there's no science to back it up it hasn't been 'known' since the 90's and it's far from a fact as you previous said, it's been speculated and speculation does not make something true.




When did I say it was speculated? It's not speculated.

Quote:

Until it's proven it's my belief vs yours. My belief, which is based on my personal experience, as I'm sure yours is based on your personal experience, is that there is no difference.




Are you talking about the alcohol thing? Because you're right there's no proof for that but there's obviously proof for cannabis..
We can see the cannabinoids bro they exist, this stuff is already known. We already know different terpenes have different and unique psychoactive effects.
There's Alpha Pinene, Myrcene, Limonene, Linalool, ect..
And that's not to mention stuff like CBN and THCV which also poise variations on the psychological effects on cannabis.
For example oxidization causes CBN to be formed which is why resin (that black shit) typically has a lot of CBN which is why resin makes you tired because that's what CBN does.

Quote:

I don't think most people can even tell a difference between a sativa and indica based on the high alone, much less trace terpenes and cannabinoids. This happens with every drug.




What do you mean "much less trace terpenes and trace cannabinoids" as oppose to different strains? That IS different strains, that's what makes different strains is different cannabinoid and terpene profiles, G13 has more myrcene than most strains just like how strains such as Jack Herer have more pinene. Sativas having more THCV than indicas, ect.

Also you're probably not going to be very good at telling indica from sativa unless they're absolutely pure and not crossed at all because the vast majority of weed is hybrid and pure sativa is just not easy to get at all.
Regardless different strains have nothing to do with this because I'm talking about the obvious difference between pure THC and the whole cannabis plant. Cannabis isn't just a drug it's a group of drugs just like shrooms and mescaline containing cacti.

And no this does not happen with every drug...
This happens with cannabis, alcohol, mescaline, ayahuasca, Ibogaine mushrooms and things like that not cocaine, or LSD or ketamine or any of these single molecule drugs.



Quote:

Look at blind taste tests with wines, you can't argue that they do most certainly taste differently, that *is* a fact, yet under a blind test people often can't even tell the difference between a white and a red a lot of the time, much less more specific differences. You should at least be open to the possibility that subjectively there really is no difference.




Why would there be a difference between red wine and white wine? Lmfao and what are the odds that even if there was differences that human beings would even be able to consciously detect it? Human beings suck at noticing shit if you haven't noticed.


Edited by AuroraBorealis88 (11/19/16 05:01 PM)


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88] * 1
    #23849313 - 11/19/16 05:16 PM (7 years, 2 months ago)

That's a lot of talk and I don't see a reference anywhere in there. If this is so well known then it should be easy to provide something reputable to back it up as I originally asked for. If you can't then there's no need to discuss this anymore, something isn't a fact because you say so, that's not how it works.

Quote:

AuroraBorealis88 said:
Human beings suck at noticing shit if you haven't noticed.




Yes I've noticed.


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OfflineAuroraBorealis88
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23849330 - 11/19/16 05:20 PM (7 years, 2 months ago)

What do you mean reference??

The chemicals exist so I don't see what you're saying.


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InvisibleThe Blind Ass
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23849347 - 11/19/16 05:27 PM (7 years, 2 months ago)

Varying amounts of psilocin, psilocynin, beosyctin, and norbeosctin (sp?) is all that differs in cubensis.. Im pretty sure.  I do find Amazon Cubensis to be different though.  IDK why maybe its just in my head, but they seem...different, cant explain it ( subjective as trips are I do imagine it is probably just in my head).


--------------------
Give me Liberty caps -or- give me Death caps


Edited by The Blind Ass (11/19/16 05:32 PM)


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23849360 - 11/19/16 05:32 PM (7 years, 2 months ago)

Quote:

AuroraBorealis88 said:

And no this does not happen with every drug...
This happens with cannabis, alcohol, mescaline, ayahuasca, Ibogaine mushrooms and things like that not cocaine, or LSD or ketamine or any of these single molecule drugs.






And that shows what you don't know. People have had this argument about LSD decades now over how pure the LSD is and if the impurities have an effect on the trip. If it has other ergolines in it that contribute to the trip or if they're impotent enough for it not to matter. I don't think they matter, but by your logic they would. We don't know conclusively, it hasn't been studied. You left off opium from the natural ones btw, there's a slew of alkaloids in there. Cocaine also is not just cocaine, I'm sure the plant produces similar alkaloids just like every other plant, some or all of the make it into the 'cocaine' that you are buying. Do they contribute to anything? Beats me.

As for the synthetic drugs you rarely have a pure drug when it comes to street drugs. Meth and other amphetamines will always be a mixture of amphetamines and/or methamphetamines. If you buy methamphetamine then you can expect methamphetamine to be the primary constituent, but it likely *does* have other psychoactive compounds in there depending how it was made. Same with mdma, you'll likely have other MDX's in there. Heroin, well it comes from opium, when you acetylate opium, eg black tar heroin, the other alkaloids don't just dissapear and leave you with pure heroin. Even if you extract the heroin to a powder it will still have at least traces of other alkaloids. Ketamine has different stereoisomers with different effects, some users prefer one over the other. Depending how it is made it too will have different related compounds, although I assume most of it comes from the pharmaceutical industry so it will be quite pure, though probably a mixture of the stereoisomers. That's all the main drugs right there is it not?


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23849367 - 11/19/16 05:35 PM (7 years, 2 months ago)

Quote:

AuroraBorealis88 said:
What do you mean reference??

The chemicals exist so I don't see what you're saying.




A reference that says anything of the sort that people get different highs from the terpenes and cannabinoids, and I mean a study or some sort of hard evidence, not reprinted hearsay. Think about what you're saying and why it does not have scientific merit.


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OfflineAuroraBorealis88
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23849457 - 11/19/16 06:03 PM (7 years, 2 months ago)

Quote:

krypto2000 said:
And that shows what you don't know. People have had this argument about LSD decades now over how pure the LSD is and if the impurities have an effect on the trip.




Of course it effects the trip, that is not even close to what I'm talking about. I'm talking about the entourage effect of certain drugs like cannabis, the term was coined from cannabis.




Quote:

You left off opium from the natural ones btw




It wasn't my intentions to list every drug with alkaloids or terpenes. Could've mentioned salvia too.

Quote:

As for the synthetic drugs you rarely have a pure drug when it comes to street drugs. Meth and other amphetamines will always be a mixture of amphetamines and/or methamphetamines. If you buy methamphetamine then you can expect methamphetamine to be the primary constituent, but it likely *does* have other psychoactive compounds in there depending how it was made. Same with mdma, you'll likely have other MDX's in there. Heroin, well it comes from opium, when you acetylate opium, eg black tar heroin, the other alkaloids don't just dissapear and leave you with pure heroin. Even if you extract the heroin to a powder it will still have at least traces of other alkaloids. Ketamine has different stereoisomers with different effects, some users prefer one over the other. Depending how it is made it too will have different related compounds, although I assume most of it comes from the pharmaceutical industry so it will be quite pure, though probably a mixture of the stereoisomers. That's all the main drugs right there is it not?




:facepalm3: again this has NOTHING to do with what I said about cannabinoids and terpenes having effects. You want me to give you a reference that these chemicals can effect the THC high? Why don't you just look up the molecules themselves and read?
I don't see why I need to tell you the moon exists and show you a source for it too. You can just Google it.


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23849497 - 11/19/16 06:13 PM (7 years, 2 months ago)

I wouldn't ask for a source if I could find one. I'm telling you one *does not exist*. You are trying to convince me of something, the burden of proof is on you. I can't find a source to prove it hasn't been studied for obvious reasons. You can find a ton of sources that say there's a difference, pop articles, forum posts, etc, half the people who smoke pot will probably say there's a difference, but that does not make it true. There is not one source that *shows* there is a difference. People hold a lot of popular beliefs that are not true.


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OfflineAuroraBorealis88
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23849717 - 11/19/16 07:40 PM (7 years, 2 months ago)

You're a wasting my time.

https://www.ncbi.nlm.nih.gov


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Offlinekrypto2000
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23849867 - 11/19/16 08:39 PM (7 years, 2 months ago)

:facepalm:


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OfflineDmt_psilocybin
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Re: Different strains, different trip? Science? [Re: agreedwitboardrule]
    #23849873 - 11/19/16 08:42 PM (7 years, 2 months ago)

Quote:

agreedwitboardrule said:
Yo

I wanted to ask,


Is there any scientific research showing that different strains of shrooms are different chemically?

The internet has people saying:

All strains are the same, they're all shrooms which all produce the same chems.

And some other people saying:

Different strains feel different, i tripped different.


I am more inclined to believe the first one, its all shrooms and all the same chems, the different trip is just peoples experience at that point in time/setting.


Thoughts?

I'd love to know 100% which is correct, if we have any scientists/100% knowing people here.

Thank you.



Varying levels of alkaloids, how they were grown, and setting. some strains of mushrooms lack certain alkaloids.


--------------------
MDMA is over rated


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OfflineAuroraBorealis88
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23849973 - 11/19/16 09:37 PM (7 years, 2 months ago)



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OfflineLogicaL ChaosM
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Re: Different strains, different trip? Science? [Re: agreedwitboardrule]
    #23850258 - 11/20/16 12:20 AM (7 years, 2 months ago)

i get subtle differen,ces in effects between strains. Its more obvious between species however.

There are no studies on it cause shrooms are illegal :sad:


--------------------
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InvisibleZymosis
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Registered: 10/17/15
Posts: 237
Re: Different strains, different trip? Science? [Re: LogicaL Chaos]
    #23850660 - 11/20/16 07:29 AM (7 years, 2 months ago)

Quote:

LogicaL Chaos said:
i get subtle differen,ces in effects between strains. Its more obvious between species however.

There are no studies on it cause shrooms are illegal :sad:




Until more scientific studies are done we will not know if the levels of actives in each strain will play a difference.  I have noticed differences in my trips from the different strains but I think this is all psychological.  My subconscious associates the strains as having certain attributes based on what the name of the strain evokes in my mind.  For example Amazonian shrooms give me a very primitive feeling trip with tribal visuals, Columbian seems like a stronger body load and is speedy, and Hawaiian is very happy and visual.  Your state of mind and subconscious contribute to your set and setting, including your thoughts on the strains.


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Offlineagreedwitboardrule
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Registered: 12/04/13
Posts: 317
Loc: Asia
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Re: Different strains, different trip? Science? [Re: PinPornProducer]
    #23850669 - 11/20/16 07:38 AM (7 years, 2 months ago)

Quote:

PinPornProducer said:
Cube trip is a cube trip, some grows are heavy on the body and less visual. Some are hardly any body load and very visual. All depends on chemical make up of the fruits. But all in all the trips are basically the same other than mind set and setting obviously



Thanks.


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Offlineagreedwitboardrule
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Re: Different strains, different trip? Science? [Re: krypto2000]
    #23850671 - 11/20/16 07:39 AM (7 years, 2 months ago)

Quote:

krypto2000 said:
There *are* a bunch of various tryptamines within the psilocybe family besides psilocin, psilocybin, and beacystine(sp?), however those are the main 3. Those three all feel indistinguishable from one another from any trip report you'll read of people who have taken the pure compounds. Now consider that beacystine(sp?) occurs at about 1% that of psilocin and psilocybin and you have to conclude that regardless how it feels it's definitely not contributing to the experience with the amounts present. By extension the other tryptamines in there are at even lesser amounts so regardless how active or different they are it's pretty safe to conclude they are not doing anything either.





Makes sense. thank you.


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Offlinekrypto2000
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Registered: 12/05/06
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Re: Different strains, different trip? Science? [Re: AuroraBorealis88]
    #23850736 - 11/20/16 08:25 AM (7 years, 2 months ago)

Quote:

AuroraBorealis88 said:
Quote:

krypto2000 said:
:facepalm:



Step 2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165946/




Did you read that study? In the very beginning it starts off by saying that the various cannabinoids have been shown to *not* produce a perceivable difference in a blind test and so they speculate that maybe terpenes have an effect. They go on to test isolated terpenes in mice and a few in humans, some present in cannabis, some not, and show what possible influence they have. They end by saying it warrants more study. That's exactly what I said from the very beginning. Most of the effects they reference are non psychosomatic as well so what effects they do have are not even related to the high.


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OfflineBANANA.MAN
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Registered: 01/11/15
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Re: Different strains, different trip? Science? [Re: Eclipse3130]
    #23852659 - 11/20/16 08:28 PM (7 years, 2 months ago)

Quote:

Eclipse3130 said:
Magic Mushrooms contain 3 main psychoactive compounds: Psilocybin, psilocin and less common and lower amounts of in dried cubensis baeocystin/norbaeocystin.

Psilocybin is the main component of magic mushrooms: Phosphoro-hydroxy-DMT
When Psilocybin passes through the liver and stomache when consumed it is dephosphorized, leaving Hydroxy-DMT otherwise known as Psilocin - this is the active drug which causes the trip.

Psilocybin, psilocin and baeocystin are found in their highest levels of fresh mushrooms. - When dried, almost to all psilocin is lost, due to the degradation in the presence of oxygen.

Baeocystin is usually unmentioned or unheard of, it's an active precursor to psilocybin but is usually found in low amounts and other species of Psilocybes.

Cubensis strains don't differ that vastly, with the exception of Penis Envy, a stable mutant hybrid cross. Set and Setting is what makes trips different, psilocybin and psilocin are always going to have the same mechanism of action in your body, certain strains aren't more visual than others, it's the amount you take, the way you consume it, your mind state and your physical surroundings which make the trip change.

:cheers:



Psilocin is 4-phosphoryloxy-N,N-dimethyltryptamine.

Psilocin is 4-hydroxy-N,N-dimethyltryptamine.

It is important to say the position the group is on. 3-OH-DMT wouldnt have the same effect as psilocin and it probably isnt even active.

5-OH-DMT is bufoteine and has different effects that psilocin so you cant just call both of them hydroxyDMT that would cause confusion.


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OfflineAuroraBorealis88
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Registered: 05/06/16
Posts: 5,871
Last seen: 5 years, 2 months
Re: Different strains, different trip? Science? [Re: krypto2000]
    #23863929 - 11/24/16 03:30 PM (7 years, 2 months ago)

Quote:

krypto2000 said:

Did you read that study? In the very beginning it starts off by saying that the various cannabinoids have been shown to *not* produce a perceivable difference in a blind test and so they speculate that maybe terpenes have an effect. They go on to test isolated terpenes in mice and a few in humans, some present in cannabis, some not, and show what possible influence they have. They end by saying it warrants more study. That's exactly what I said from the very beginning. Most of the effects they reference are non psychosomatic as well so what effects they do have are not even related to the high.




Smh I wasn't saying they were psychoactive on their own. They need THC to make any sort of conscious changes.


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