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grizzlyadams
Trippy Hippy



Registered: 09/10/16
Posts: 187
Last seen: 7 months, 7 days
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How does DMT hit so fast?
#23759917 - 10/22/16 03:33 AM (7 years, 4 months ago) |
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I was wondering if anyone could tell me how does DMT hit so quickly? Im kinda of in amazement of how quickly the chemical reaches your brain so fast. I understand that DMT isn't exactly a molecule of this world in my experience, but how is it possible for the effects to set in so quickly. Even blood can't pump that quickly! DMT is purely amazing!
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pablokabute
Hari ng Amag



Registered: 11/22/11
Posts: 5,179
Loc: rural ghetto
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DMT is purported to be one of the main building blocks (derivative of tryptophan) of life and therefore consciousness so 'it is a molecule of this world.'
if blood cant pump that fast then how do you think DMT gets in your brain? DMT gets vaporized, or incinerated, then to your lungs, then to your 'bloodstream', then blood-brain barrier, then to your brain receptors...
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Eggtimer
HotSauce Lover

Registered: 05/04/13
Posts: 3,097
Last seen: 1 hour, 56 minutes
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Quote:
grizzlyadams said: I was wondering if anyone could tell me how does DMT hit so quickly? Im kinda of in amazement of how quickly the chemical reaches your brain so fast. I understand that DMT isn't exactly a molecule of this world in my experience, but how is it possible for the effects to set in so quickly. Even blood can't pump that quickly! DMT is purely amazing!
It is one of the few chemicals your brain expends energy to get it across the BBB. You're smoking it too... that helps 
https://www.researchgate.net/profile/Ede_Frecska/publication/236339046_A_possibly_sigma-1_receptor_mediated_role_of_dimethyltryptamine_in_tissue_protection_regeneration_and_immunity/links/02e7e52c6816e599bd000000.pdf
Quote:
In essence, DMT is passing through three barriers with the help of three different active transport mechanisms to be compartmentalized and stored within the brain. In this manner, high intracellular and vesicular concentrations of DMT can be achieved within neurons. The outlined stages of uptake reveal that considerable physiological effort is exerted for the accumulation and storage of DMT and suggest that it has vital importance, since only a few compounds such as glucose and amino acids are known to be treated with similar priority. These extensive specialized processes would not have evolved to target a toxic compound or merely because of the psychedelic effects of DMT.
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Dark_Star
train driver pervading a desktop


Registered: 08/20/04
Posts: 31,859
Loc: Uranus
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It's the ROA. You're inhaling the vapors into your lungs, where it's absorbed into your bloodstream & pumped throughout your body....the process of which is very rapid. Smoking/vaping actually hits a bit quicker then IV, as the blood has two paths; it's pumped to the heart > lungs to expel carbon dioxide & become oxygenated > back to the heart & then throughout the body to deliver the oxygen & nutrients to your cells. Once the DMT crossed the BBB it's readily accepted, then rapidly broken down.
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dankbark
Stranger
Registered: 10/19/16
Posts: 32
Last seen: 7 years, 4 months
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Re: How does DMT hit so fast? [Re: Dark_Star]
#23761051 - 10/22/16 02:01 PM (7 years, 4 months ago) |
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quicker "than" IV
like smoking something. It goes into the lungs.
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omnifarious
Stranger


Registered: 02/14/11
Posts: 43
Last seen: 6 years, 9 months
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Re: How does DMT hit so fast? [Re: dankbark]
#23786316 - 10/30/16 05:14 PM (7 years, 3 months ago) |
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smoking is the fastest route to a spiritual place but I do think IV gets in the blood quicker. Maybe smoking goes through the blood brain barrier quicker?
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Ech0
Stranger

Registered: 10/18/16
Posts: 163
Last seen: 5 years, 9 months
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same as when you smoke anything?
weed, tobacco etc, all hit as fast
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