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Offlinegrizzlyadams
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Registered: 09/10/16
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How does DMT hit so fast?
    #23759917 - 10/22/16 03:33 AM (7 years, 4 months ago)

I was wondering if anyone could tell me how does DMT hit so quickly?  Im kinda of in amazement of how quickly the chemical reaches your brain so fast.  I understand that DMT isn't exactly a molecule of this world in my experience, but how is it possible for the effects to set in so quickly.  Even blood can't pump that quickly! DMT is purely amazing!

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Invisiblepablokabute
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Registered: 11/22/11
Posts: 5,179
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Re: How does DMT hit so fast? [Re: grizzlyadams]
    #23759990 - 10/22/16 04:54 AM (7 years, 4 months ago)

DMT is purported to be one of the main building blocks (derivative of tryptophan) of life and therefore consciousness so 'it is a molecule of this world.'

if blood cant pump that fast then how do you think DMT gets in your brain?
DMT gets vaporized, or incinerated, then to your lungs, then to your 'bloodstream', then blood-brain barrier, then to your brain receptors...


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OfflineEggtimer
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Registered: 05/04/13
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Re: How does DMT hit so fast? [Re: grizzlyadams]
    #23760518 - 10/22/16 10:37 AM (7 years, 4 months ago)

Quote:

grizzlyadams said:
I was wondering if anyone could tell me how does DMT hit so quickly?  Im kinda of in amazement of how quickly the chemical reaches your brain so fast.  I understand that DMT isn't exactly a molecule of this world in my experience, but how is it possible for the effects to set in so quickly.  Even blood can't pump that quickly! DMT is purely amazing!




It is one of the few chemicals your brain expends energy to get it across the BBB.
You're smoking it too... that helps :lol:

https://www.researchgate.net/profile/Ede_Frecska/publication/236339046_A_possibly_sigma-1_receptor_mediated_role_of_dimethyltryptamine_in_tissue_protection_regeneration_and_immunity/links/02e7e52c6816e599bd000000.pdf
Quote:

In essence, DMT is passing through three barriers with
the help of three different active transport mechanisms to
be compartmentalized and stored within the brain. In this
manner, high intracellular and vesicular concentrations of
DMT can be achieved within neurons. The outlined stages
of uptake reveal that considerable physiological effort is
exerted for the accumulation and storage of DMT and
suggest that it has vital importance, since only a few
compounds such as glucose and amino acids are known to
be treated with similar priority. These extensive specialized
processes would not have evolved to target a toxic compound
or merely because of the psychedelic effects of
DMT.




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It's all for the :lol:s

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InvisibleDark_Star
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Registered: 08/20/04
Posts: 31,859
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Re: How does DMT hit so fast? [Re: grizzlyadams]
    #23760595 - 10/22/16 11:02 AM (7 years, 4 months ago)

It's the ROA. You're inhaling the vapors into your lungs, where it's absorbed into your bloodstream & pumped throughout your body....the process of which is very rapid. Smoking/vaping actually hits a bit quicker then IV, as the blood has two paths; it's pumped to the heart > lungs to expel carbon dioxide & become oxygenated > back to the heart & then throughout the body to deliver the oxygen & nutrients to your cells. Once the DMT crossed the BBB it's readily accepted, then rapidly broken down.


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Offlinedankbark
Stranger
Registered: 10/19/16
Posts: 32
Last seen: 7 years, 4 months
Re: How does DMT hit so fast? [Re: Dark_Star]
    #23761051 - 10/22/16 02:01 PM (7 years, 4 months ago)

quicker "than" IV

like smoking something.  It goes into the lungs.

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Offlineomnifarious
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Registered: 02/14/11
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Last seen: 6 years, 9 months
Re: How does DMT hit so fast? [Re: dankbark]
    #23786316 - 10/30/16 05:14 PM (7 years, 3 months ago)

smoking is the fastest route to a spiritual place but I do think IV gets in the blood quicker. Maybe smoking goes through the blood brain barrier quicker?

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OfflineEch0
Stranger

Registered: 10/18/16
Posts: 163
Last seen: 5 years, 9 months
Re: How does DMT hit so fast? [Re: grizzlyadams]
    #23790436 - 11/01/16 04:50 AM (7 years, 3 months ago)

same as when you smoke anything?

weed, tobacco etc, all hit as fast


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[gradient:#FF009D,#]PEACE[/gradient]

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